c********r
发帖数: 189 | 1 【 以下文字转载自 Neuroscience 讨论区 】
发信人: coollester (生与死), 信区: Neuroscience
标 题: 神经领域做epigenetics的大牛都有谁啊？
发信站: BBS 未名空间站 (Wed Jun 20 08:44:37 2012, 美东)
各位畅谈一下？我知道的有宋红军，做DNA methylation&neurogenesis |
n********k
发帖数: 2818 | 2 what directions do you want, there are quite some, to name a few: Michael
Greenberg at HARVARD, Swatt at UAB; Eric nestler at Mount Sinai; Houda
Zoghbi at Baylor, Jin Peng @ emory is shooting up too; lihui Tsai in MIT,
【在 c********r 的大作中提到】
: 【 以下文字转载自 Neuroscience 讨论区 】
: 发信人: coollester (生与死), 信区: Neuroscience
: 标 题: 神经领域做epigenetics的大牛都有谁啊？
: 发信站: BBS 未名空间站 (Wed Jun 20 08:44:37 2012, 美东)
: 各位畅谈一下？我知道的有宋红军，做DNA methylation&neurogenesis
|
i**y
发帖数: 71 | 3 It's a messy field. Try Gerald Crabtree and Alexander Schier
【在 c********r 的大作中提到】
: 【 以下文字转载自 Neuroscience 讨论区 】
: 发信人: coollester (生与死), 信区: Neuroscience
: 标 题: 神经领域做epigenetics的大牛都有谁啊？
: 发信站: BBS 未名空间站 (Wed Jun 20 08:44:37 2012, 美东)
: 各位畅谈一下？我知道的有宋红军，做DNA methylation&neurogenesis
|
n********k
发帖数: 2818 | 4 I agree, in a way, the entire epigenetic field is messy...anyhow, why these
two? I know both of them are smart...
【在 i**y 的大作中提到】
: It's a messy field. Try Gerald Crabtree and Alexander Schier
|
i**y
发帖数: 71 | 5 No particular reasons... I feel their works are relatively more mechanistic
than most other "neuro-epigenetists". Schier doesn't even study epigenetics
in the nervous system. He just happens to study both Rudolf Jaenisch is good
too, although he doesn't seem to work as much on epigenetics as before.
these
【在 n********k 的大作中提到】
: I agree, in a way, the entire epigenetic field is messy...anyhow, why these
: two? I know both of them are smart...
|
n********k
发帖数: 2818 | 6 I c, I agree both are very good scientifically and have vision too...u also
said, Schier actually is not in anyway in epigenetic field; Jerry runs hard
core epigenetic lab and has done beautiful and systematic work on the field
but he is really not a neural guy, nor Jaenisch..., as well, Jerry's later
work is more hot than systematic i would say...
mechanistic
epigenetics
good
【在 i**y 的大作中提到】
: No particular reasons... I feel their works are relatively more mechanistic
: than most other "neuro-epigenetists". Schier doesn't even study epigenetics
: in the nervous system. He just happens to study both Rudolf Jaenisch is good
: too, although he doesn't seem to work as much on epigenetics as before.
:
: these
|
h******1
发帖数: 16295 | 7 我咋觉得epigenetics没啥前途呢？尤其是跟风做的那些人。 |
i**y
发帖数: 71 | 8 I really like his new paper in Cell, which really leads the epigenetics
field in the direction of addressing causality in vivo... Didn't Schier
publish a paper in Nature on the early establishment of epigenomes in embryo
? I think there is some effort in his lab to address the causative roles of
epigenetic modifications on transcription as well.
Most current neurobiologists who are interested in epigenetics are only
explaining transcriptional phenomena in the language of epigenetics. Very
few are really making any contribution to epigenetic mechanisms per se.
also
hard
field
【在 n********k 的大作中提到】
: I c, I agree both are very good scientifically and have vision too...u also
: said, Schier actually is not in anyway in epigenetic field; Jerry runs hard
: core epigenetic lab and has done beautiful and systematic work on the field
: but he is really not a neural guy, nor Jaenisch..., as well, Jerry's later
: work is more hot than systematic i would say...
:
: mechanistic
: epigenetics
: good
|
l******e
发帖数: 427 | 9 as always, i put a big question mark on Lihui Cai's work... |
n********k
发帖数: 2818 | 10 xu:)) we are not hiding behind network anymore:)))
【在 l******e 的大作中提到】
: as always, i put a big question mark on Lihui Cai's work...
|
n********k
发帖数: 2818 | 11 Are u a biochemistry/molecular biologist? I think some of the mechanistic
questions should not count on neurobiologists at all...I heard ys ago,
Schier's interests are more in behavior and circuitry...
embryo
of
【在 i**y 的大作中提到】
: I really like his new paper in Cell, which really leads the epigenetics
: field in the direction of addressing causality in vivo... Didn't Schier
: publish a paper in Nature on the early establishment of epigenomes in embryo
: ? I think there is some effort in his lab to address the causative roles of
: epigenetic modifications on transcription as well.
: Most current neurobiologists who are interested in epigenetics are only
: explaining transcriptional phenomena in the language of epigenetics. Very
: few are really making any contribution to epigenetic mechanisms per se.
:
: also
|
i**y
发帖数: 71 | 12 yes i am, so i'm very much biased =) though i do use the brain as an
experimental system from time to time
【在 n********k 的大作中提到】
: Are u a biochemistry/molecular biologist? I think some of the mechanistic
: questions should not count on neurobiologists at all...I heard ys ago,
: Schier's interests are more in behavior and circuitry...
:
: embryo
: of
|
y**i
发帖数: 78 | 13 which paper are you talking about? Can you please share the link or title of
the paper? Thanks
embryo
of
【在 i**y 的大作中提到】
: I really like his new paper in Cell, which really leads the epigenetics
: field in the direction of addressing causality in vivo... Didn't Schier
: publish a paper in Nature on the early establishment of epigenomes in embryo
: ? I think there is some effort in his lab to address the causative roles of
: epigenetic modifications on transcription as well.
: Most current neurobiologists who are interested in epigenetics are only
: explaining transcriptional phenomena in the language of epigenetics. Very
: few are really making any contribution to epigenetic mechanisms per se.
:
: also
|
i**y
发帖数: 71 | |
