m*******3
发帖数: 25 | 1 刘春明在JIPB上发表的对APB1的commentary
http://www.jipb.net/pubsoft/content/2/10.1111/jipb.12339.pdf
Science is a global community enterprise. Collectively, we contribute to
building the
knowledge tower by using bricks and mortar that should be strong, solid, and
long
lasting. A brick with defects may lead this tower, or a part there of, to
collapse. When
that happens, the community suffers, laying waste countless dedicated hours
of work,
especially by students and postdoctoral scholars. This is the reason... 阅读全帖 |
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s***e
发帖数: 5242 | 2 "The Chinese team reported editing the genes of more than 80 embryos using a
technology called CRISPR-Cas9. While in some cases they were successful, in
others the CRISPR technology didn’t work or introduced unexpected
mutations. Some of the embryos ended up being mosaics, with a repaired gene
in some cells but not in others." |
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A******y
发帖数: 2041 | 3 The problem: "Huang's group successfully introduced the DNA they wanted in
only "a fraction" of the 28 embryos that had been "successfully spliced" (
they tried 86 embryos at the start and tested 54 of the 71 that survived the
procedure). They also found a "surprising number of ‘off-target’
mutations," according to Nature News." |
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l*******i
发帖数: 153 | 4 首先我明确自己的态度：反对现在做这样直接修饰human embryo的实验。
但是，如果大家还有印象的话，几周前，有人在版里贴了一个新闻，说是Church实验室
正在用CRISPR技术修饰human embryo，而且是一个中国女博后牵头的。当时外界的反应
似乎比现在要积极。为什么现在中国的实验室先做出来了，大家都一致批判了呢，质疑
伦理问题？Nature上的评论，有的说得很直接，而且与计划生育牵扯到一起。
另外，说这个价值不大的，那是低估了这项实验的巨大影响力。”设计婴儿“不久之前
还只是科幻电影中的桥段；再联想到去年谢晓亮与北大三院合作，运用单细胞测序技术
，”筛选“出健康婴儿的事实，大家难道还没意识到”设计婴儿“眼睁睁地几乎变成现
实了吗？
科学的发展，总是领先伦理一步。研究者不应忽视伦理，但是如果囿于伦理的限制，那
么科学也不会进步。特别是医学，总是在一次又一次突破当时的伦理限制中进步的。
这次，也不例外，也无法避免。 |
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s**2
发帖数: 1287 | 5 你说 “Jaenisch 是个跟风大王”，你大概是指他近几年在干细胞方面的工作吧？
我一点也不喜欢 Rudy Jaenisch 这个人。不过他早年的工作还是杠杠的。
以下是wiki上摘来的。希望不是象“张诺贝尔”那样，自己编录的。哈哈哈
Jaenisch’s first breakthrough occurred in 1974 when he and Beatrice Mintz
showed that foreign DNA could be integrated into the DNA of early mouse
embryos.[4] They injected retrovirus DNA into early mouse embryos and showed
that leukemia DNA sequences had integrated into the mouse genome and also
to its offspring. These mice were the first transgenic mammals in history.[5] |
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c*********r
发帖数: 1312 | 7 Xenopus细胞不同embryo之间以及同一个embryo之内的细胞的周期高度同步吗？ |
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r*s
发帖数: 2555 | 8 Want to enjoy bacon without the guilt? Scientists are using a gene-editing
tool to create low-fat pigs, so you can.
Chinese researchers recently conducted an experiment, published in the
Proceedings of the National Academy of Scientists, to determine how
genetically modified pigs can “improve pig welfare and reduce economic
losses,” the study said.
To do so, they used a tool called CRISPR to produce a gene that helps pigs
burn fat to stay warm. While other mammals, such as mice and rats, already... 阅读全帖 |
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l****z
发帖数: 29846 | 9 看看这个吧,应该更快更有疗效.
Embryonic Cloning Shows Promise in Diabetes Treatment
Healthy Stem Cells Extracted From Embryonic Clone and Changed Into Cells
That Produce Insulin
For the second time in recent weeks researchers said they used cloning
technology on adult tissue, rather than from a fetus or infant, to create
stem cells that potentially could be used to treat a range of diseases.
Researchers said Monday they created an embryonic clone of a 32-year-old
woman with diabetes, extracted healthy stem ce... 阅读全帖 |
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J*R
发帖数: 187 | 10 Dr. Zi Chen (currently at Washington University in St. Louis and will start
a tenure-track position at Dartmouth in 2015) is looking for prospective PhD
students to start in 2015. Visiting or postdoctoral positions may also be
available for highly qualified candidates. A successful candidate will work
on one or multiples of the following topics: mechanics of morphogenesis in
plants/embryos, fast motion of plants (e.g., the Venus flytrap's rapid
closure), mechanical self-assembly and instability ... 阅读全帖 |
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l*******8
发帖数: 290 | 11 和大家比，非常失败，96。
所以就把自己的教训总结一下，希望大家不要犯我的错误。
先转贴一个我最常参考的一个考经，这个对大家更有意义。
arsenal_vaibhav - 11/10/10 10:02 Hi guys! Thought I would post my exam
experience for everyones benefit...
Gave the exam on 9/11/10 expecting result by 1st dec...
My prep: All kaplan books (except patho and anat) approx twice
Goljan audio once
Goljan book approx twice
FA approx twice
HY Cell and molec bio once
100 cases in ethics once
Kaplan Q book full
Robbins patho question book full
UW 90% solved mixed timed 83%
UWSA 1&2 ... 阅读全帖 |
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l*******8
发帖数: 290 | 12 和大家比，非常失败，96。
所以就把自己的教训总结一下，希望大家不要犯我的错误。
先转贴一个我最常参考的一个考经，这个对大家更有意义。
arsenal_vaibhav - 11/10/10 10:02 Hi guys! Thought I would post my exam
experience for everyones benefit...
Gave the exam on 9/11/10 expecting result by 1st dec...
My prep: All kaplan books (except patho and anat) approx twice
Goljan audio once
Goljan book approx twice
FA approx twice
HY Cell and molec bio once
100 cases in ethics once
Kaplan Q book full
Robbins patho question book full
UW 90% solved mixed timed 83%
UWSA 1&2 ... 阅读全帖 |
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i*****s
发帖数: 15215 | 13 今年是第38届，优胜者将在一周后公布，建议看原帖大图，链接在下面。
What you looking at? This picture by Nikola Rahme from Budapest, Hungary,
shows a parasitic wasp peering into the lens of a microsope.
See no evil, speak no evil, detect the precise
location of evil using ultrasonic echoes: This image by University of
Cambridge researcher Dorit Hockman shows embryos of the black mastiff bat.
Spiky: Harold Taylor of Kensworth, Dunstable, entered this picture of a
house spider's face.
Baby love: This picture by Geir Drange shows a... 阅读全帖 |
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s*********e
发帖数: 36 | 14 这个是houston诊所的数据
Fresh Embryos From Non-Donor Oocytes <35岁
Number of cycles 132
Percentage of cycles resulting in pregnancies 54.5
Percentage of cycles resulting in live births 50.8
这个是我现在所在的诊所的数据
Fresh Embryos From Non-Donor Oocytes <35岁
Number of cycles 82
Percentage of cycles resulting in pregnancies 30.5
Percentage of cycles resulting in live births 29.3
我所在的诊所做的例数不算很少，只是成功率低了太多 |
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a**e
发帖数: 381 | 15 Without insurance, it's about 14k one cycle with fresh embryos.
I decide to take 2-cycle package that's about 24k with 2 cycle of fresh
embryos.
The two cycle package deal, you can choose money back if it fails the first
time, or continue to the second cycle. I'm not sure if every clinic has that
package. |
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a*******l
发帖数: 116 | 16 我的理解是，assisted hatching一般是岁数大一些的建议做，这里很多jms移植的是
day 5的blastocyst。但是这2个都是要听医生建议的，尤其blastocyst culture,我觉
得不是自己选择的，是医生根据当时embryo的情况决定做到什么stage.这就是医生一般
在ER以后并不能马上告诉你是第三天还是第五天ET,因为要看embryo的发展情况。
价钱方面不了解。 |
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a*********r
发帖数: 296 | 17 有的研究说Day 5 transfer blastocyst成功的可能性大一些。
我们诊所是这样，如果DAY 3时好的EMBRYO不多，就DAY 3 TRANSFER,因为外界的环境不
会比子宫更好。如果DAY 3时好的EMBRYO比较多，就推迟到DAY 5 TRANSFER。
但是我知道有的诊所只做DAY 3 TRANSFER，好像也挺好。 |
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k******3
发帖数: 41 | 18 要看个人具体情况,说说我的情况,仅供MM参考:我当时取了28个卵,20 matured,17
fertilized, 8 developed into blastocysts.IVF之前做过腹腔镜(后来给我做IVF的老美医生做的),发现左边卵巢有轻微子宫内膜异位,医生做了处理,告诉我无大碍...后来又做了三次IUI(Clomaid)未果,他才建议的IVF.
Stimulate用的Gon-F Pen,我的respond很强,两边卵巢都有10多个卵泡按同等速度生长,中途医生减了Gon-F药量,取卵的前一天晚上用Lupron instead of HCG to trigger ovulation to prevent OHSS (ovarian hyperstimulation syndrome).我自身反应并不大,有时觉得头有点晕,照常上班到取卵的前一天,取卵后没有吐,麻药的作用下我在路上睡着了,回到家麻药过了也不疼...第1次IVF fresh cycle移植了1 embryo,没成,但因为有frozen embryos,不用重新刺激卵巢.这次做frozen cycle怀上了...
谨慎 |
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a*********r
发帖数: 296 | 19 It's not worth doing it. PGD doesn't live up to its promise, statisticlly it
doesn't help with IVF success rate. Besides, the approach is invasive, it
took one cell out of the several cells the embryo has, it may harm the
embryo. |
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y**h
发帖数: 574 | 20 comfort.
I think you need to relax, although I knew that's difficult.
You are not old yet, so still a lot of opportunities. I guess Cornell might
be strict with the quality of the embryos, do they only transfer the top
quality embryo to ensure the high successful rate? That could eliminate your
chances too, since their judgement is highly subjective, not objective. |
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t*******e
发帖数: 912 | 21 我的这个DAY５ ET可不是什么好事。昨天他们说了，假如今天看见两个好的８CELL的
EMBRYO就是DAY３ ET，假如不清楚就等到DAY ５。今天没发现好的所以要继续观察。很
担心啊，别人DAY ５的都是因为有好的一大把EMBRYOS，我只有６个啊。 |
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t*********o
发帖数: 123 | 22 Westmore, hope you are doining well and not suffering too much from morning
sickness.
I have a question on Saizen．
You mentioned you started using it after follicles >14mm, so how many ml
have you used in your cycle? Do you think it helped to improve the egg and
embryo quality? From the outcome, it looks that it helped.
Also, may I ask you several "how many' questions?
How many eggs retrived, how many matured, and how many got ferterlized and
how many availble embryo numbers for transfer? Day 3 |
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A****y
发帖数: 337 | 23 tigerbaobao，
祝福你的6个embryos全都健康的发育成长！
关于assisted hatching，我在RMA-NJ的时候有做过，RMA是NJ最highly rated的IVF诊
所，他们的common practice是所有的DAY3 transfer都做assisted hatching，是为了
帮助embryos孵化，容易在子宫着床。我当时有问道是否是年龄大于35岁的卵子会有较
硬的zona，所有AH有帮助。其实医生告诉我，就算是年轻的卵子，在实验室的培养液也
有可能硬化zona，不利于着床。 我想你大可放心的做的！
你取卵后，今天感觉如何？希望你好好恢复，准备好周五的TRANSFER！
Lots of blessings！ |
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A****y
发帖数: 337 | 24 1）Beta HCG 简称 Beta 是指 "the pregnancy hormone" is produced by the cells
of the implanting egg and can be produced in the absence of an embryo。试管
后的怀孕检查就是查Beta HCG，所以也叫beta test。
2）E２= Estradiol level；是除了FSH以外重要的指标
3）ER = Egg Retrivel
4）ET = Embryo Transfer |
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k**a
发帖数: 1124 | 25 so mm did day 3 transfer even though you had so many embryos? now i think
day 3 transfer may not be a bad idea. i had 9 8-cell embryos on day 3 and 5
were all wasted. :(
憾，我当时没做记录，现在只能大体把能想起的都做出汇报吧。
要求十分准确。
医生了，手术是位男医生操作的，年龄比较大，很和蔼可亲，在推我去手术房前，又搂
搂又抱抱的，让我觉得很温暖。还问我感觉如何呢，我说肚子太涨了，大了好几圈呢，
他开玩笑说，这是我们让你这样的，我们希望更严重呢。清醒过来后，医生告诉我取卵
21颗，很成功，回家等电话吧。同时也安排了开始每天注射黄体酮。
（注意：这时开始一定注意便秘，我因为便秘吃了很大苦头，要多吃fibre，便秘一旦
发生就要用药物解决，以防用力伤害到卵巢）
密朋友，都建议我们植三个胚胎，好，就这么决定了，一路高歌到了医院，等了好久，
我的主治医生出现了，是位女医生，我觉得她是位很正直善良做事也很保守的医生，真
的很庆 |
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G*********a
发帖数: 328 | 26 Copied from a website:
Day transfer -
1dpt... Embryo is growing and developing
2dpt... Embryo is now a blastocyst
3dpt... Blastocyst hatches out of shell on this day
4dpt... Blastocyst attaches to a site on the uterine lining
5dpt... Implantation begins,as the blastocyst begins to bury in the lining
6dpt... Implantation process continues and morula buries deeper in the
lining
7dpt... Morula is completely inmplanted in the lining and has placenta cells
&
fetal cells
8dpt... Placenta cells begin t |
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t********y
发帖数: 18 | 27 这是第一次ivf (长周期protocol ,本人高龄>35，以前从未怀孕过，也未接受过iui）
，这次移植的是day3 的 2个 8-cell 的胚胎，day3 移植的姐妹们要有信心。
我在ivf之前的例行检查中查出有甲减，后开始服用 levothroxine，mock embryo
transfer 时查出有子宫内膜息肉，ivf 医生给我做了宫腔镜摘除了息肉，他说息肉会
影响到胚胎的。我觉的mock embryo transfer 挺重要的，否则一般的妇科检查是查不
出子宫内膜息肉的。
我是从11月中旬开始作stimulation,用的是lupron，gonal-f和menopur,12 天后取卵15
个，有6个受精卵，3天后移植2个8cell的胚胎（2个最好级别的胚胎），当时还郁闷没
有day5 transfer，现在想每个人的情况不同，day3 不一定就比day5的成功率低。
我从取卵后的当天就出现了ohss的症状（取卵时e2 是3000 多，hcg trigger shot 只
用了5000u），但是因为我事先没有重视，当天晚上就有明显的腹涨和腹痛，第二天打
电话给护士，又让 |
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b*******y
发帖数: 12791 | 28 谢谢你，希望我的egg能乖乖成embryo，然后embryo能很强壮，我从小吃的那些鱼啊，
肉啊，虾阿的不要浪费 |
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y********g
发帖数: 3 | 29 大家好，我是新会员。有一个问题想请教大家。谢谢啦。
我做过两次IVF,没有成功。有两个Embryos frozen。现在想做embryos transfer。医生
建议先做输卵管切除手术。原因是我有过一次宫外孕。当时作了内窥镜手术。输卵管虽
然保住了，但右侧输卵管留下了永久伤疤而且不通。输卵管不通会影响IVF的成功，所
以建议将两侧输卵管切除。我现在很忧郁。不知道该怎么办。我的左侧输卵管还好，但
医生不建议自然怀孕，害怕再会有一次宫外孕。IVF是我唯一的选择。但要切除输卵管
，我有一点忧郁。请教大家，我是否应该作这个手术？ |
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y********g
发帖数: 3 | 30 大家好，我是新会员。有一个问题想请教大家。谢谢啦。
我做过两次IVF,没有成功。有两个Embryos frozen。现在想做embryos transfer。医生
建议先做输卵管切除手术。原因是我有过一次宫外孕。当时作了内窥镜手术。输卵管虽
然保住了，但右侧输卵管留下了永久伤疤而且不通。输卵管不通会影响IVF的成功，所
以建议将两侧输卵管切除。我现在很忧郁。不知道该怎么办。我的左侧输卵管还好，但
医生不建议自然怀孕，害怕再会有一次宫外孕。IVF是我唯一的选择。但要切除输卵管
，我有一点忧郁。请教大家，我是否应该作这个手术？ |
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j*******7
发帖数: 6300 | 31 http://cclw.net/gospel/explore/mdjhl/htm/03.htm
每一个人的胚胎在发育过程中都有一个鱼的时期，外形跟鱼的胚胎相似到离奇的程
度呢？
生物学在自然科学中，是最复杂又是最年轻的一门学科。百多年来不断地成长，到
如今可以说达到突飞猛进的地步。每天在新闻报导中都可以听到有新的生物学发现。不
少人都认为廿一世纪肯定是生物学的世纪。在这成长的过程中，随著观察和实验的增加
，当然会修正过去的一些错误。
但是在1997年，生物学上有一个重大的发现，这个发现不是“修正”过往的错误，
而是揭开了生物学历史上最大的丑闻（注１），也可以说是最大的骗局－－科学家兼名
教授海克尔伪造图片、蓄意欺骗。
但是据我所知，在美国除了两家科普性的杂志（注2）（注3）对此做了简单报导之
外，各大城市的报章杂志都丝毫没有反应。偌大的事，就这样石沈大海吗？幸好有基督
徒的努力，在 1999年，才出现较详细和公允的报导（注4）（注5）。
。。。。。。
英国伦敦有一位医生李察逊（Richardson），他也是胚胎学家，花了一生的时间研
究人的胚胎，但他从来没有见过人胚胎有“鱼”的阶段！所... 阅读全帖 |
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o***s
发帖数: 42149 | 32 近日，美国一对白人夫妇Aaron和Rachel Halbert产下一对黑人三胞胎。这是基因变异还是喜当爹？然而夫妻二人却还很开心，原来两人是通过供精者的剩余胚胎体外受精的，也就是三胞胎是试管婴儿，跟这对父母没多大关系，因为两人并没有生育能力。
令人惊讶的是，这对夫妇目前已经收养了5个黑人孩子，其中包括刚产下的这对三胞胎。
Aaron和Rachel Halbert两人是基督教长老会会员，从两人相认开始，他们就决定领养非裔美国人（即美国黑人），而不是跟他们肤色一样的白种人。因为他们知道，白人孩子在很多方面都比黑人孩子受到优待，他们觉得，黑人孩子更需要得到关心和平等对待，每年都有太多的黑人孩子被无辜抛弃，甚至没人领养。
在这对福音派信徒夫妇领养了两个黑人孩子后，他们觉得这两个孩子的生活有了翻天覆地的变化，能给他们带来全新的生活是一件多么美好的事情。
Aaron和Rachel Halbert亲眼见证了领养的两个黑人孩子生活的感人变化，他们想要收养更多的黑人孩子，而且最好不是高加索血统的。因为两人没有生育能力，他们最终选择来到了National Embryo Donation Center，一家... 阅读全帖 |
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w*l
发帖数: 2550 | 33 http://somloquesembrem.files.wordpress.com/2010/07/arisleblanc2
该文检测两种除草剂（GLYP和GLUF)及其代谢物，以及一种CryAb1 Bt毒蛋白在母体及胎
儿血液的含量。
结果：
GLYP及其代谢物：未检测到。
GLUF未检测到。其代谢物3-MPPA普遍存在 （On the other hand,3-MPPA(the
metabolite of GLUF)was detected in 100% of maternal and umbilical cord blood
samples,and in 67% of the nonpregnant women’s blood samples），含量较高 （
8-417 ng/mL）。
GLUF对人的正常发育有不利影响 （Garciaetal. [37] investigated the potential
teratogenic effects of GLUF in humans found and increased risk of congenital
malforma... 阅读全帖 |
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d********a
发帖数: 3698 | 34
美国现在还没有转基因的小麦和水稻
转基因这种东西在科研上是必须要搞的，但远不到大规模普及的程度。中国来个大跃进
搞到水稻和小麦上让人吃有些急了。
以现在中国社会一切向钱看的风气，大规模搞转基因主食潜在的危险可能远远超过眼前
利益，况且还又是一小部分人的利益。
================================
人体内检测出多种转基因毒素，转基因核心谎言被戳穿
翻译评论：加拿大一个彻底戳穿转基因谎言的划时代重要研究
作者/译者：半解一知半解
评论：鉴于长期以来， 国内外转基因的讨论与推广已严重偏离科学的轨道，成了一个
利益和政治问题，所以， 有必要矫枉过正把这个问题还原回科学的轨道。
不可否认， 转基因技术本身是一种科学， 但同样不可否认，不是所有的科学技术都是
完美无缺、有益无害的，转基因是一种未经严格验证、其安全性还存在很多未知和不确
定性的技术，是一种存在巨大争议和巨大风险的技术，因为这项技术涉及到食品及食品
安全，所以，在实验室进行研究、完善无可质疑，但如果大面积推广，就应该受到质疑
乃至反对。这应该是目前大多数反转基因民众和仁人志士的基本共识。
而国内外转基因势... 阅读全帖 |
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i*****s
发帖数: 4596 | 35 http://www.nytimes.com/2013/02/15/science/studying-recent-human
East Asian Physical Traits Linked to 35,000-Year-Old Mutation
By NICHOLAS WADE
Published: February 14, 2013
Gaining a deep insight into human evolution, researchers have identified a
mutation in a critical human gene as the source of several distinctive
traits that make East Asians different from other races.
The traits — thicker hair shafts, more sweat glands, characteristically
identified teeth and smaller breasts — are the re... 阅读全帖 |
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e*****s
发帖数: 7359 | 36 观云图有感。
Every individual, no matter what species you are, is part of a larger game.
intra/interspecies competition, eating or being eaten, it's all about the
evolution of genetic information. You make it, you pass your copy of genetic
information to future generations which again will be playing the same game
, no guarantee for continuous winning. You lose; you still contribute to the
game by providing food, raw materials and lessens. The glory of any
advancement in this evolutionary process bear... 阅读全帖 |
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f***y
发帖数: 4447 | 37 The DNA methylation landscape of human early embryos
....Fuchou Tang & Jie Qiao
Affiliations
Contributions
Corresponding authors
Nature (2014) doi:10.1038/nature13544 Received 10 November 2013 Accepted
30 May 2014 Published online 23 July 2014
Alterations of the human gut microbiome in liver cirrhosis
.... S. Dusko Ehrlich, Shusen Zheng & Lanjuan Li
Affiliations
Contributions
Corresponding authors
Nature (2014) doi:10.1038/nature13568 Received 07 April 2013 Accepted 09
June 2... 阅读全帖 |
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g**a
发帖数: 2129 | 38 Those embryonic cells are engineered not to develop into a real embryo. 71/
86 survived, but only 28 with successful DNA repair who also have a lot of
unintended mutations in exomes.That is actually the main point of this paper
. The technique is not safe nor effective, period! |
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x********e
发帖数: 35261 | 40 你基因改造大部分情况下只能在体外做，做了要搞transgenic生物必须用克隆技术。虽
说现在直接往embryo里面注射CRISPR DNA/RNA也可以，但像猪这种大型动物，没办法用
成体去筛。 |
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g***j
发帖数: 40861 | 41 【 以下文字转载自 Biology 讨论区 】
发信人: SWJSJ (BC), 信区: Biology
标 题: 单开一贴，浙大范衡宇涉嫌更加严重的剽窃和学术不端！
发信站: BBS 未名空间站 (Thu Sep 17 23:38:04 2015, 美东)
靠，实在是看着不爽，凭啥清北撕逼就大家一致讨伐，浙大范衡宇更加恶劣的剽窃别人
成果却没人关注？下面转帖，是从张生家和谢灿那个帖子里看到的，其他几位ID不愿意
单开一贴，我实在看不下去，特开一贴。这个范衡宇据说还拿到了杰青，国内科研真是
尼玛无底线了啊。
如果有知道内情的，在此帖讨论吧，不然都被清北的刷屏了。当然，也许有其他隐情冤
枉了范衡宇，也可以内部人出来解释解释。如果确定是剽窃，这尼玛妥妥的应该上新语
丝头条啊。
以下转帖：
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发信人: forjoy (三分华盖), 信区: Biology
标 题: Re: 能拿炸药奖吗？
... 阅读全帖 |
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m**c
发帖数: 7349 | 42 “In my opinion, Crispr could in principle be used to boost the expected
intelligence of an embryo by a considerable amount,” said James J. Lee, a
researcher at University of Minnesota, one of the authors of that study. “
But "in principle" does a lot of work here.
One practical obstacle is that we still do not have a reliable means of
determining the causal site(s) responsible” for the association. In other
words, Lee cautioned me that just because a genetic variant is associated
with a quantita... 阅读全帖 |
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l*******1
发帖数: 16217 | 43 CRISPR 这个绝对该得，我刚才查了一下 中国和美国FDA 今年已经批准肺癌试验了，前
面英国的报道过治愈过白血病，
The Chinese trial will enrol patients who have metastatic non-small cell
lung cancer and for whom chemotherapy, radiation therapy and other
treatments have failed. “Treatment options are very limited,” says Lu. “
This technique is of great promise in bringing benefits to patients,
especially the cancer patients whom we treat every day.”
Leukaemia success heralds wave of gene-editing therapies
Lu’s team will extract immune cells called T... 阅读全帖 |
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s******g
发帖数: 437 | 44 Reddit 通俗易懂的说法：
Have you ever cracked open an egg and seen a small spot of blood? That small
spot contains thousands of cells (red blood cells, blood vessels, etc).
That small spot also contains the embryo of the chicken, as it is slowly
developing. Give that small blood spot enough time (assuming it hasn't died
because of the cold), and it will eventually develop into a chicken.
The whole chicken egg, as in the whole yolk and egg white, isnot a cell. A
cell that big would never actually work be... 阅读全帖 |
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n********d
发帖数: 7676 | 45 这个傻逼还有一项主要成就是 Dickey-Wicker Amendment (1995)， which prohibits
federal funds to be spent on research that involves the destruction of a
human embryo。共和党里的这些基督神棍们对做IVF的大妈们不是一般的恨啊。 |
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x****6
发帖数: 4339 | 46 看题目，都是学术前沿的工作，屁挨着地水平的。
以马公和千老领域为主。
Picoscale Mechanics of Atomically Engineered Materials
Optical Control of Protein Assembly and Activity in Cell-Like-Compartments
Cell Membrane-Coated Nanodevice for Anti-Virulence Therapy Against
Antibiotic Resistant Bacteria
Artemisinin as a Potential Parkinson's Disease Treatment via Alleviation of
α-Synuclein Mediated Neuronal Damage and Inflammation
Exploring Posterior Growth in D. rerio Using a Live Cell Cycle Biosensor
Modeling the Spatio-Temporal Dynami... 阅读全帖 |
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t**x
发帖数: 20965 | 47 A baby was born in China four years after the death of his parents, after
his grandparents were able to recover a frozen embryo implanted in a
surrogate mother, a Chinese media outlet reported.
The child, named “Tiantian” (“sweet-sweet” in Chinese), was born on
December 9, 2017, revealed last week the Chinese news outlet Xinjingbao. His
parents, Shen Jie and his wife Liu Xi, were on infertility treatment when
they died in 2013 in a car accident. The mom and the dad were the only
children of the... 阅读全帖 |
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w********2
发帖数: 632 | 48 Gene transfer refers to the movement of genes within or between individual
organisms. HGT is often used to refer to all forms of gene transfer that do
not involve parent- to-offspring transfer (sexual or asexual). It can occur
ei- ther naturally or by human intervention (e.g. gene tech- nology, embryo
rescue, in vitro fertilization, protoplast fusion, self-cloning). In some
cases, HGT may be tran- sient, and not perpetuated in the offspring. Each
form of HGT comes with different considerations o... 阅读全帖 |
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k**********4
发帖数: 16092 | 50 Most of the ethical discussions related to genome editing center around
human germline editing. This is because changes made in the germline would
be passed down to future generations. The debate about genome editing is not
a new one but has regained attention following the discovery that CRISPR
has the potential to make such editing more accurate and even "easy" in
comparison to older technologies.
Bioethicists and researchers generally believe that human genome editing for
reproductive purpose... 阅读全帖 |
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