p*******r
发帖数: 4048 | 1 The author seems to think that the track record has been good last decade
but going forward is quite bleak.
Maybe some change in the whole business model is needed?
http://www.nature.com/nbt/journal/v30/n8/full/nbt.2334.html
Can biotech spur job creation?
The report also notes, however, that in the drugs and pharmaceuticals
subsector there was an overall loss of 9,400 jobs between 2001 and 2010.
Indeed, since 2008, the bioscience industry as a whole has shed thousands of
jobs, with overall employment failing to rebound to the levels before the
credit crunch.
An industry starved of funding from the bottom up is not an industry that
will create jobs. And contrary to BIO and Battelle's rosy picture, past
performance in the sector is no guarantee of future results. The truth is,
outside Boston and the Bay Area, biotech does not seem like a good bet for
job growth. In fact, urging governments to bet limited public funding on the
sector with the promise of job creation might even be downright misleading. | d*****r
发帖数: 2583 | 2 maybe it's not only the business model, the whole research model needs to be
changed.
of
【在 p*******r 的大作中提到】
: The author seems to think that the track record has been good last decade
: but going forward is quite bleak.
: Maybe some change in the whole business model is needed?
: http://www.nature.com/nbt/journal/v30/n8/full/nbt.2334.html
: Can biotech spur job creation?
: The report also notes, however, that in the drugs and pharmaceuticals
: subsector there was an overall loss of 9,400 jobs between 2001 and 2010.
: Indeed, since 2008, the bioscience industry as a whole has shed thousands of
: jobs, with overall employment failing to rebound to the levels before the
: credit crunch.
| g********0
发帖数: 6201 | 3 根本原因在于传统的筛小分子的成功速度已经低于专利过期的速度，整个产业在向负面
发展，药厂也没法在实验室里养这么多吃干饭的闲人了。 | b******k
发帖数: 2321 | 4 筛选本身问题不大 问题是target出来的速度越来越慢吧。这个也不奇怪，low hanging
fruit都吃完了，下来的要么是根本没有单一target,要么是target很难被target(不再
是GPCR,kinase这种的了)。
【在 g********0 的大作中提到】
: 根本原因在于传统的筛小分子的成功速度已经低于专利过期的速度，整个产业在向负面
: 发展，药厂也没法在实验室里养这么多吃干饭的闲人了。
| g********0
发帖数: 6201 | 5 就是这个意思。
现在还搞单靶点药物就有点守株待兔的意思了。
而新兴的所谓系统生物学还基本上象算命的一样，解决不了什么实际问题。
hanging
【在 b******k 的大作中提到】
: 筛选本身问题不大 问题是target出来的速度越来越慢吧。这个也不奇怪，low hanging
: fruit都吃完了，下来的要么是根本没有单一target,要么是target很难被target(不再
: 是GPCR,kinase这种的了)。
| M*P
发帖数: 6456 | 6 这个比叶诗文事件还更应该抗议。Nature editorial office吃屎了？没有biotech的投
入，你们journal就要关门了。
of
【在 p*******r 的大作中提到】
: The author seems to think that the track record has been good last decade
: but going forward is quite bleak.
: Maybe some change in the whole business model is needed?
: http://www.nature.com/nbt/journal/v30/n8/full/nbt.2334.html
: Can biotech spur job creation?
: The report also notes, however, that in the drugs and pharmaceuticals
: subsector there was an overall loss of 9,400 jobs between 2001 and 2010.
: Indeed, since 2008, the bioscience industry as a whole has shed thousands of
: jobs, with overall employment failing to rebound to the levels before the
: credit crunch.
| u**********d
发帖数: 573 | 7 算命，系统生物学的人被一枪穿了7个洞
【在 g********0 的大作中提到】
: 就是这个意思。
: 现在还搞单靶点药物就有点守株待兔的意思了。
: 而新兴的所谓系统生物学还基本上象算命的一样，解决不了什么实际问题。
:
: hanging
| n******7
发帖数: 12463 | 8 我也觉得系统生物学现在就是搞笑的啊
花钱发paper而已
【在 u**********d 的大作中提到】
: 算命，系统生物学的人被一枪穿了7个洞
| x******m
发帖数: 736 | 9 你告诉我，生物基础领域，那个不是花钱发paper？
【在 n******7 的大作中提到】
: 我也觉得系统生物学现在就是搞笑的啊
: 花钱发paper而已
|
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