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全部话题 - 话题: viral
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z*****8
发帖数: 2546
1
来自主题: Family版 - 儿子的Viral video (转载)
【 以下文字转载自 Living 讨论区 】
发信人: zhang88 (david), 信区: Living
标 题: 儿子的Viral video
发信站: BBS 未名空间站 (Tue Nov 11 13:47:48 2014, 美东)
儿子的Viral video
l****o
发帖数: 8
2
来自主题: JobMarket版 - Job openings in Viral Immunology
Founded in 1957, Lanzhou Veterinary Research Institute http://www.chvst.com/English_web/Index.aspx, or http://www.chvst.com), Chinese Academy of Agricultural Sciences (LVRI, CAAS) is one of the most outstanding institutes in the field of preventive veterinary medicine in China. The research of our institute is mainly focusing on infectious diseases (viral and bacterial) and parasitic diseases of veterinary science, and zoonosis, specific to diagnosis, vaccinology, immunology, and preventive and... 阅读全帖
l****o
发帖数: 8
3
来自主题: JobMarket版 - Job openings in Viral Immunology
Founded in 1957, Lanzhou Veterinary Research Institute http://www.chvst.com/English_web/Index.aspx, or http://www.chvst.com), Chinese Academy of Agricultural Sciences (LVRI, CAAS) is one of the most outstanding institutes in the field of preventive veterinary medicine in China. The research of our institute is mainly focusing on infectious diseases (viral and bacterial) and parasitic diseases of veterinary science, and zoonosis, specific to diagnosis, vaccinology, immunology, and preventive and... 阅读全帖
m******8
发帖数: 2153
4
来自主题: QueerNews版 - Gay Marine’s homecoming kiss goes viral
http://news.yahoo.com/blogs/lookout/gay-marine-homecoming-kiss-
Five months after the military's ban on openly gay service expired, a photo
of a young gay Marine's homecoming kiss has gone viral.
Nearly 15,000 people have liked the picture on Facebook, which was posted in
a group for gay Marines on Saturday.
The Marine, Brandon Morgan, posted a response on his Facebook wall according
to the JoeMyGod blog. "To everyone who has responded in a positive way. My
partner and I want to say thank you. D... 阅读全帖
s***k
发帖数: 256
5
See how those people from those banned country would treat Americans. Hope
all lefts pay a visit to those countries and we will be so grateful.
http://www.foxnews.com/us/2017/02/10/marine-vet-speaks-out-about-viral-video-supporting-trump-travel-ban.html
z*****8
发帖数: 2546
z*****8
发帖数: 2546
7
来自主题: Living版 - 儿子的Viral video
儿子的Viral video
z*****8
发帖数: 2546
8
来自主题: Living版 - 儿子的Viral video
儿子的Viral video
z*****8
发帖数: 2546
J*****s
发帖数: 110
10
前两天应该是吃坏了东西,导致头痛,发烧和腹泻。
到ER,医生给我输液,抽血化验。结果是viral性的。
医生给我开了Vicodin止痛药和止泻的药。
这两天没啥好转,问题依旧。
我找到当天吃的食物,我的想法是,如果打电话到医院,把食物去化验,能不能找到解
药?
Thanks.
e********0
发帖数: 259
11
来自主题: Windows版 - problems after viral infection (转载)
【 以下文字转载自 Software 讨论区 】
发信人: enhancer00 (enhancer), 信区: Software
标 题: problems after viral infection
发信站: BBS 未名空间站 (Tue Dec 30 15:30:25 2008)
My system is currently infected with virus (malware), and I followed an
instruction to disinfect the virus
under safe mode, but now stuck in the following delima:
If I start the PC under safe mode (with F8), then it turned blue screen,
saying you have to disinfect the
virus first;
If I try to load windows regularly, it takes forever so I cannot get to t
z**m
发帖数: 50
12
本人生物菜鸟,请教版上牛人,万分感谢!!!
想检测老鼠体外培养细胞中病毒感染前期,病毒RNA是否和目标蛋白结合成RNP complex。
目标蛋白IP抗体available,想检测的viral RNA 为40-50 nt的leader sequence (
LeRNA)。
做了些homework,准备用目标蛋白pulldown,PK处理,纯化RNA组分,northern检测。
问题:
1)由于个人原因,不想用同位素标记探真做northern,不知可否用dig-probe做
northern,主要担心RNA量太少,不知道dig的灵敏度是否足够。
2)由于目标RNA只有40-50 nt,请问northern 的DNA或RNA probe是否只能是这40-
50nt的序列?如果probe只有40-50 nt,是否太短?尤其是用dig-UTP标记?可否适当
延长probe至200 nt-300nt(后续sequence是病毒的另外一个高表达基因,如果该基因
mRNA也和目标蛋白结合最好,如果不和目标蛋白结合,是否延长的probe检测不到40-50nt的leRNA?)
3)除了northern,
s*******e
发帖数: 1544
13
http://www.usnews.com/science/articles/2009/10/28/the-hidden-co
Contents Provided by National Science Foundation:
University Park, Pa.—Genetically modified squash plants that are resistant
to a debilitating viral disease become more vulnerable to a fatal bacterial
infection, according to biologists.
"Cultivated squash is susceptible to a variety of viral diseases and that is
a major problem for farmers," said Andrew Stephenson, Penn State professor
of biology. "Infected plants grow more slowly a... 阅读全帖
p*******r
发帖数: 59
14
Career Opportunities at JCVI Infectious Disease (8 Positions)
The PIs did not ask me to post here, I did this just in case someone is
looking for similar positions but did not see these, and I would be happy to
see some chinese fellows to come. All the PIs are very nice.
All listed at
https://careers.jcvi.org/careers/Careers.aspx
http://www.jcvi.org/
No. 1 & No. 2 Post-Doctoral Fellows
Job Responsibilities
JCVI is looking for two Post-Doctoral Fellows to join the Infectious Disease
Group in our ... 阅读全帖
C*I
发帖数: 4736
15
一直在误导,现在还在误导。 说说明corona virus 不可以从蝙蝠直接传染给人,必须
经过一个中间宿体性的其它动物才能传染给人。所以,病毒发生后,就故意误导全国人
民去海鲜市场找证据,找其它野生动物的麻烦。 而且还是病毒所去找的,找完了还装
模做样化验呀,分离呀什么的。最后把责任全部推给了海鲜市场的动物。可是那种动物
,一直不敢说,说了其它相关已经在人就会去早那种动物监测。 所以压根不说,打马
虎眼。
事实上,早在2013 年,就是这个武汉病毒研究所,已经从来自云南的蝙蝠身上所携带
的corona virus中分离出第一株蝙蝠SARS类似样的冠状病毒的活病毒,其中就包含了类
似于S类型的基因。从而证实这株病毒能够使其接受和SARS病毒相同的受体,并能够感
染人的细胞。对此新发现,武汉病毒所还把它以武汉病毒研究所的英文简称命名“WIV1
”,以彰显这一发现的重要价值和属于自己第一个发现的巨大研究成果。这个成果刊载
于2013年11月的《自然》杂志。
就是说,从云南弄回来的这种蝙蝠所携带的类似于sars的 corona virus, 可以不经过
其它受体/宿体,而直接传染给人。 他们... 阅读全帖
C*I
发帖数: 4736
16
一直在误导,现在还在误导。 说说明corona virus 不可以从蝙蝠直接传染给人,必须
经过一个中间宿体性的其它动物才能传染给人。所以,病毒发生后,就故意误导全国人
民去海鲜市场找证据,找其它野生动物的麻烦。 而且还是病毒所去找的,找完了还装
模做样化验呀,分离呀什么的。最后把责任全部推给了海鲜市场的动物。可是那种动物
,一直不敢说,说了其它相关已经在人就会去早那种动物监测。 所以压根不说,打马
虎眼。
事实上,早在2013 年,就是这个武汉病毒研究所,已经从来自云南的蝙蝠身上所携带
的corona virus中分离出第一株蝙蝠SARS类似样的冠状病毒的活病毒,其中就包含了类
似于S类型的基因。从而证实这株病毒能够使其接受和SARS病毒相同的受体,并能够感
染人的细胞。对此新发现,武汉病毒所还把它以武汉病毒研究所的英文简称命名“WIV1
”,以彰显这一发现的重要价值和属于自己第一个发现的巨大研究成果。这个成果刊载
于2013年11月的《自然》杂志。
就是说,从云南弄回来的这种蝙蝠所携带的类似于sars的 corona virus, 可以不经过
其它受体/宿体,而直接传染给人。 他们... 阅读全帖
C*I
发帖数: 4736
17
Published: 30 October 2013
Isolation and characterization of a bat SARS-like coronavirus that uses the
ACE2 receptor
Xing-Yi Ge, Jia-Lu Li, Xing-Lou Yang, Aleksei A. Chmura, Guangjian Zhu,
Jonathan H. Epstein, Jonna K. Mazet, Ben Hu, Wei Zhang, Cheng Peng, Yu-Ji
Zhang, Chu-Ming Luo, Bing Tan, Ning Wang, Yan Zhu, Gary Crameri, Shu-Yi
Zhang, Lin-Fa Wang, Peter Daszak & Zheng-Li Shi
Nature volume 503, pages535–538(2013)Cite this article
Abstract
The 2002–3 pandemic caused by severe acute respirator... 阅读全帖
W*****B
发帖数: 4796
18
仔细一看这篇还是个华人写的
白人可能大部分还不知道这个情况
CORONAVIRUS
What We Need to Understand About Asymptomatic Carriers if We’re Going to
Beat Coronavirus
ProPublica’s health reporter Caroline Chen explains what the conversation
around asymptomatic coronavirus carriers is missing, and what we need to
understand if we’re going to beat this nefarious virus together.
ProPublica is a nonprofit newsroom that investigates abuses of power. Sign
up to receive our biggest stories as soon as they’re published.
In the early days... 阅读全帖
w******9
发帖数: 1604
19
Submitted
Missel AR, Bai M, Klug WS, Levine AJ, The Affine to Non-affine Transition in
Anisotropic Semiflexible Networks.
Roos WH, Gibbons MM, Arkhipov A, Uetrecht C, Watts NR, Wingfield PT, Steven
AC, Heck AJR, Schulten K, Klug WS, Wuite GJL, Squeezing protein shells: how
continuum elastic models, moleculardynamics simulations and experiments
coalesce at the nanoscale.
Published
Morozov AY, Rudnick J, Bruinsma RF and Klug WS, Assembly and Disassembly of
Deltahedral Viral Shells. In: Stockley, P... 阅读全帖
z*t
发帖数: 863
20
Beutler得奖,Medzhitov会不会有意见?
http://www.sciencedirect.com/science/article/pii/S1074761309002
Ruslan Medzhitov
This year marks the 20th anniversary of a publication (Janeway, 1989) that
in many ways revolutionized our understanding of the immune system. As part
of the proceedings of the Cold Spring Harbor Symposium on Immune Recognition
, the paper authored by the late Charles A. Janeway, Jr. was not a standard
peer-reviewed publication. In fact, Charlie used to refer to it as “the
best paper I've ... 阅读全帖
l*****7
发帖数: 8463
21
It is very simple!!!
WHY the 转基因食品 is unsafe ????
BECAUSE nobody have proven it is safe!!!!!!
1) Vectors (Viral DNA, Viral RNA) carry out the genetic alteration of plants
(addition, deletion, alteration):
Do these vectors also carry additional DNA segments that have proven harms
to human???? In this case, it is a genetic weapon.
2) Infectiousness of the vectors (Viral DNA, Viral RNA) carrying out
genetic alteration:
The more infectious the vectors are, the more likely it will be incorporated
... 阅读全帖
l*****7
发帖数: 8463
22
发信人: luke837 (Optionist---炒变), 信区: Biology
标 题: 转基因食品 are absolutely SAFE ????
发信站: BBS 未名空间站 (Mon Sep 3 14:40:34 2012, 美东)
Anybody who claims 转基因食品 are absolutely SAFE are UNRESPONSIBLE!!!!It is
very simple!!!
WHY the 转基因食品 is unsafe ????
BECAUSE nobody have proven it is safe!!!!!!
1) Vectors (Viral DNA, Viral RNA) carry out the genetic alteration of plants
(addition, deletion, alteration):
Do these vectors also carry additional DNA segments that have proven harms
to human???? In this case, i... 阅读全帖

发帖数: 1
23
来自主题: Military版 - 阿三大嘴PPT,你们也信?
http://theprepared.com/blog/no-the-2019-ncov-genome-doesnt-actually-seem-engineered-from-hiv/
2019-nCoV genome doesn’t really seem engineered from HIV
A group of bioinformaticians at two prestigious universities in Delhi, India
, published a preprint scientific manuscript on the bioRxiv preprint server
Friday has led many to speculate wildly that 2019-nCoV may have been
deliberately engineered using HIV protein sequences.
The paper, entitled “Uncanny similarity of unique inserts in the 2019-nCoV... 阅读全帖
M*V
发帖数: 3205
24
来自主题: Salon版 - 转基因食品
转基因食品
The very simple reason:
WHY the 转基因食品 is unsafe ????
BECAUSE nobody have proven it is safe!!!!!!
1) Vectors (Viral DNA, Viral RNA) carry out the genetic alteration of plants
(addition, deletion, alteration):
Do these vectors also carry additional DNA segments that have proven harms
to human???? In this case, it is a genetic weapon.
2) Infectiousness of the vectors (Viral DNA, Viral RNA) carrying out
genetic alteration:
The more infectious the vectors are, the more likely it will be incorpo... 阅读全帖
p*e
发帖数: 6785
25
来自主题: Joke版 - 男女老少都在讨论色盲裙
https://www.linkedin.com/pulse/thedressthe-viral-phenomenon-why-tai-tran?trk
=tod-home-art-list-large_0
The Virality of #TheDress Explained
Feb 27, 2015 48,757Views 446Likes 127CommentsShare on
LinkedInShare on
FacebookShare on Google PlusShare on Twitter
Virality = (Pathos + Ethos + Logos) x (Timeliness + Relevance)
Virality is the holy grail of marketing and advertising, yet the mechanics
behind it is still fully not understood. Many brands attempt to create viral
content to no a... 阅读全帖
w********2
发帖数: 632
26
来自主题: Military版 - gmo食品最大的问题
HGT involving viruses
Viruses undergo frequent HGT but this is typically re- stricted to gene
exchange between viral genomes present in the same infection. Many viral
genomes have few genes (less than 10), which constrains the number and types
of genes that can be expected to increase or even maintain fitness.
Consequently, viruses with small genomes have been rarely reported to
contain non- virally derived genetic elements (Agranovsky et al., 1991;
Becker, 2000; Khatchikian et al., 1989; Masuta... 阅读全帖
G****e
发帖数: 1912
27
来自主题: Military版 - 千老们来反驳一下?
https://www.theepochtimes.com/scientific-puzzles-surrounding-the-wuhan-novel
-coronavirus_3225405.html
Scientific Puzzles Surrounding the Wuhan Novel Coronavirus
BY YUHONG DONG February 3, 2020 Updated: February 6, 2020FONT BFONT SText
size Print
Analysis
The sudden outbreak of the Wuhan Novel Coronavirus (2019-nCoV) has resulted
in all of China’s Hubei Province and three major cities in Zhejiang
Province being subjected to quarantine. Other nations are anxiously trying
to get their people out o... 阅读全帖
m******i
发帖数: 73
28
http://web.mit.edu/press/2011/antiviral.html
New drug could cure nearly any viral infection
Researchers at MIT’s Lincoln Lab have developed technology that may someday
cure the common cold, influenza and other ailments.
CAMBRIDGE, Mass. — Most bacterial infections can be treated with
antibiotics such as penicillin, discovered decades ago. However, such drugs
are useless against viral infections, including influenza, the common cold,
and deadly hemorrhagic fevers such as Ebola.
Now, in a developm... 阅读全帖
v*****s
发帖数: 20290
29
【 以下文字转载自 Joke 讨论区 】
发信人: mutouhui (mutouhui), 信区: Joke
标 题: Re: 麻省科学家发现病毒克星“天龙”
发信站: BBS 未名空间站 (Sun Nov 13 19:08:54 2011, 美东)
http://web.mit.edu/press/2011/antiviral.html
New drug could cure nearly any viral infection
Researchers at MIT’s Lincoln Lab have developed technology that may someday
cure the common cold, influenza and other ailments.
CAMBRIDGE, Mass. — Most bacterial infections can be treated with
antibiotics such as penicillin, discovered decades ago. However, such drugs
are useless... 阅读全帖
m****a
发帖数: 6
30
来自主题: MedicalCareer版 - 朋友乙肝求助,请了解的好心人支招
hi, I have a friend, male, 40 year old, alcoholic history and with hepatitis
B, liver function test is abnormal ( the case is almost same as your friend
). The doctor in China provide him IFN and his WBC drop to below 500. then
stop it, he only use entacavir, after only three month his viral load start
to decrease and 6 month later his viral load is less than 1000. his Liver
function is normal, he has taken entacavir for almost 3 years, all lab tests
are normal. another case is female 42 years o... 阅读全帖
n**e
发帖数: 2026
31
关于马甲问题。我没有证据证明某ID不是nile的马甲。也没有义务证明某人是nile的马
甲。所以不作任何解释和表态。有人说某ID是nile的马甲,应该谁主张谁举证。本人多
次要求对方出示证据。流氓admin威胁人肉我的email邮箱。但是始终没有拿出任何证明
某ID是nile马甲的证据。这里给一个反证:Dreamer论坛有人证明nile的IP地址与某人
的IP地址不同。
发信人: Dreamer (不要问我从哪里来), 信区: Dreamer
标 题: Re: 我看微镜所言并无不妥 (转载)
发信站: BBS 未名空间站 (Sat Apr 5 00:05:54 2014, 美东)
微镜和你的IP不一样,我相信你是个诚实的人,微镜不是你,尽管我跟你的观点不尽相
同,这也很正常。
本人将在生物版的三个相关辩论转贴过来。请大家看看,某人所说『当初在生物版那么
多人质疑你,指出你逻辑的问题,拿出pubmed原文跟你对质,你就不辩了,开始倒地打
滚说质疑你的人都是网络流氓』是不是真的。欢迎补充。
发信人: nile (nile), 信区: Biology
标 题: Re: 素食给我健康之—... 阅读全帖
s******r
发帖数: 5309
32
来自主题: Military版 - 女疮轮把儿子扔公车底下给废了
大妈疮轮是疮轮里的战斗机。 这儿子再也别想找女朋友,更别提当海军了。有个疮轮
娘还不如死了算了。
‘This is MY son’: Navy vet horrified as mom’s tweet miscasts him as #
HimToo poster boy — and goes viral
Pieter Hanson then and now. (Courtesy of Pieter Hanson)
By Meagan Flynn October 9 at 5:51 AM
Pieter Hanson was in the middle of a marketing exam when his phone started
blowing up, buzzing and buzzing until he was convinced something terrible
had happened. Too anxious to focus, he whizzed through the rest of his test,
handed it in to his Univers... 阅读全帖

发帖数: 1
33
99%那个是华南农业大学弄出来的,
和这篇在武肺爆发前就发表的文章没有任何关联,
人们在对这篇文章进行回顾性分析时,才有了新的发现,和新冠受体结合蛋白97%氨基
酸序列相同,引起我的注意,顺腾摸瓜,找到了这边文章
http://virological.org/t/ncov-2019-spike-protein-receptor-binding-domain-shares-high-amino-acid-identity-with-a-coronavirus-recovered-from-a-pangolin-viral-metagenomic-dataset/362
nCoV-2019 Spike Protein Receptor Binding Domain Shares High Amino Acid
Identity With a Coronavirus Recovered from a Pangolin Viral Metagenomic
Dataset
Novel 2019 coronavirus
nCoV-2019 Evolutionary History
torptube... 阅读全帖

发帖数: 1
34
英文媒体也报道了
https://apnews.com/Business%20Wire/fe24e251ddb843a9b091561a06f8eead
Clover Initiates Development of Recombinant Subunit-Trimer Vaccine for Wuhan
Coronavirus (2019-nCoV)
CHENGDU, China--(BUSINESS WIRE)--Jan 28, 2020--
Clover Biopharmaceuticals, a global clinical-stage biotechnology company
focused on developing novel and transformative biologic therapies, today
announced that it has initiated development of a recombinant subunit vaccine
for 2019-nCoV, the newly identified coronavirus tha... 阅读全帖

发帖数: 1
35
来自主题: JobMarket版 - 【招聘】武汉大学
替人发帖,有兴趣的同志们请直接联系他们
http://www.whu.edu.cn/info/1118/5588.htm
-------------------------------------分割线---------------------------------
----------------
武汉大学面向海内外公开招聘
病毒学国家重点实验室主任的启事
武汉大学是国家教育部直属重点综合性大学,是国家“985工程 ”和“211工程 ”重点
建设高校。病毒学国家重点实验室于2004年批准立项建设,是我国开展病毒学基础理论
与应用基础研究、培养病毒学高层次人才、促进病毒学及其相关领域国际国内科研合作
与学术交流的重要基地,在病毒遗传变异与分子流行病学、病毒与细胞相互作用的分子
机理、病毒的免疫与致病机制和病毒病的防治基础研究等方面取得了一批高水平、原创
性的研究成果。为进一步提高科研水平与学术地位,加快重点实验室和世界一流大学的
建设步伐,经研究,现面向海内外公开招聘病毒学国家重点实验室主任,热忱欢迎海内
外专家学者前来应聘。现将有关事项公告如下:
一、任职条件
1、具有良好的个人品... 阅读全帖
c*******u
发帖数: 12899
36
☆─────────────────────────────────────☆
littlehei (嘿嘿) 于 (Thu Mar 10 19:27:29 2011, 美东) 提到:
上大学新生入学体检的时候第一次检查出来,众目睽睽下几个肝感觉阳性的同学给点名
,被校医区别对待了,甚
至游泳卡也过了好久才拿到。。。当时只觉得无地自容,感觉被歧视了。
//幸好后来好像没有再这么被当众羞辱过。出国的体检,工作以后每年的体检都没有很
多废话。
后来我自己一直很注意这个方面的话题。得知我父亲年轻的时候得过乙肝,家里的孩子
成为乙肝病毒携带者也是
十有八九的事。虽然医学上说这个病毒携带是不可治愈也不可逆转的,还是相信民间偏
方吃了不少中药。小三阳
还是小三阳,姐姐是大三阳的,据说一度变成小三阳,现在不知道。因为美国好像没有
大小三阳的说法。
一直风平浪静的直到怀孕。第一trimester血结果出来以后,产科医生似乎有点紧张。
然后州政府的health
department给我打电话,说要把我登记在案。让我LG去打肝炎预防针,说小孩出生的几
个小时内得打第一针预防
针,期间各种血液体液样... 阅读全帖
m****x
发帖数: 2506
37
来自主题: Fishing版 - 肉忠被恶心了
http://forums.pondboss.com/ubbthreads.php?ubb=showflat&Forum=7&
找到了,看来鱼泛滥的地方容易长虫。 鱼多不是好事
Parasites and Disease
At some time an outbreak of some type of disease or parasite will likely
occur. However, the severity, frequency and duration of these outbreaks can
be reduced by controlling fish stress. Conditions favorable for disease
outbreaks require a host, such as the fish, a disease organism such as a
parasite and a stress such as low dissolved oxygen. Common stress factors
are rough handling, w... 阅读全帖
d*********e
发帖数: 1918
38
Duke Graduate Karen Owen Gives Women the Power to Point
Comments (0) | TrackBacks (0)
Tess Goodwin | October 10, 2010
Staff Reporter
Well-written and hilariously titled, "An Education Beyond The Classroom:
Excelling In The Realm Of Horizontal Academics,” is now the subject of a
media frenzy. Karen Owen, a recent graduate of Duke, made this powerpoint
presentation detailing her sexual conquests while she was a student and
since then, it has gone viral.
Duke University (Courtesy Creative Commons)
... 阅读全帖
g*********d
发帖数: 233
39
Here is some literature I found....
I'm interested in this gene
Thanks!
2'-5'-oligoadenylate synthetase 1 is an enzyme that in humans is encoded
by the OAS1 gene.[1][2]
This gene encodes a member of the 2-5A synthetase family, essential
proteins involved in the innate immune response to viral infection. The
encoded protein is induced by interferons and uses adenosine triphosphate
in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-
oligoadenylates (2-5As). These molecules activate ... 阅读全帖
g*********d
发帖数: 233
40
MicroRNA 和病毒
作者:王磊
上海交通大学生命学院研究生
摘要:
microRNA(miRNA)是真核生物体内一组内源性的 21—25nt 长的非编码蛋白质的短序列
RNA,它们能通过碱基配对的方式与生物体中的 mRNA 分子相结合来参与调节基因的表
达。自 2000 年至今,miRNA 的研究发展的速度极快并且影响的范围也非常的广泛,而
且分别在2002年和2003年度中miRNA入选了Science杂志年度十大科技突破。因此,
miRNA是 RNA 研究的又一个突破,被称为 RNA 的第二次革命。目前的研究已发现
miRNA 参与了很多重要的生命活动过程涵盖了发育、凋亡、代谢、人类疾病以及病毒侵
染等方面。在病毒侵染宿主和宿主抵抗病毒的过程中病毒编码的 miRNAs 和宿主编码的
miRNAs 均发挥了重要的作用。这无疑为病毒的侵染以及宿主抵抗病毒的侵染的研究提
供了新的思路和新的领域。因此,本文的主要目的在于阐述 miRNA 的一些基本概况以
及在病毒中主要的研究方向和进展,最后对这个具有跨时代意义的小分子进行展望。
关键词:miRNA vmiRNA 功能 宿主的 miR... 阅读全帖
g*****n
发帖数: 250
41
来自主题: Biology版 - 接着读乙肝病毒受体论文
I speculated, yesterday, how they picked NTCP as a candidate receptor for
HBV. There is nothing wrong to select a candidate based on knowledge. The
key is to determine whether that is the one you are looking for with
evidence. Let’s see how they tested whether NTCP is the receptor for HBV.
(1) They transfected NTCP into cells, cross-linked the viral proteins,
and ran Western. Again, overexpression, forced linking, all are too
artificial. They should look at the native NTCP protein, but they ... 阅读全帖
B******o
发帖数: 496
42
The vector does look weird. First, what is the promoter for the viral
expression. Usually, if it is MMLV, then the promoter is contained in 5'LTR,
so the viral genome is transcribed from there. Otherwise, people will put a
CMV in front of 5'LTR to express it. Without a promoter, the viral genome
will not be expressed and packaged into virus particles.
Second, I never saw anybody inserted Ori within a viral genome. It is very
weired. Not sure how it will affect your gene expression.
Third, poly A... 阅读全帖
e****0
发帖数: 678
43
来自主题: MedicalCareer版 - [我的CK]儿科
• leukemia
ALL AML CLL
child adult elderly
BM lymphoblasts 25%myeloblasts
lab Lymphocyte 5000, mature-appearing cells
• Osgood-schlatters disease
 Adolescent male athletes
 Traction apophysitis—quadriceps tendon put the traction on the
apophysis of the tibial tubercle where patellar tendon inserts.
 A firm mass =heterotopic bone formation
 Pain can be reproduced by extending the kne... 阅读全帖
t*******o
发帖数: 1464
44
Telaprevir is in a race with a similar drug called boceprevir being
developed by Merck & Co (MRK.N).
Data from two more Phase III trials of telaprevir, including results in
patients who failed with previous treatment, is expected in the third
quarter. The first boceprevir late-stage data will be released later this
year.
======================================
http://www.reuters.com/article/idCNN2520494620100525?rpc=44
A hepatitis C treatment being developed by Vertex Pharmaceuticals Inc (VRTX.
O... 阅读全帖
a*******s
发帖数: 117
45
来自主题: Military版 - 厦大中专院长夏宁邵所发表论文
以下为部分论文。 若有错误,欢迎指正。
夏宁邵所在领域还是偏应用,非基础研究。 亮点是2010年的一篇柳叶刀。
2012年度:
Quantitative hepatitis B core antibody level may help predict treatment
response in chronic hepatitis B patients.
Yuan Q, Song LW, Liu CJ, Li Z, Liu PG, Huang CH, Yan Y, Ge SX, Wang YB, Peng
CY, Zhang J, Kao JH, Chen DS, Chen PJ, Xia NS.
Gut. 2012 Jun 14. [Epub ahead of print] No abstract available.
影响因子: 10.614
Hepatitis E virus: neutralizing sites, diagnosis, and protective immunity.
Zhang J, Li SW, Wu T, Zhao Q, Ng MH, Xia NS.
... 阅读全帖
W*****B
发帖数: 4796
46
当时情况很复杂。黑犹太人率先挑衅,呛声高中白学生,和印第安人。高中生们回应。
印第安老头又跑过来瞎掺合。最后乱套了。
当事白人学生叫Nick sandman,只是站着啥都没做。结果成了众矢之的。
Fuller Picture Emerges of Viral Video Between Native American Man and
Catholic Students
A fuller and more complicated picture emerged on Sunday of the videotaped
encounter between a Native American man and a throng of high school boys
wearing “Make America Great Again” gear outside the Lincoln Memorial in
Washington.
Interviews and additional video footage suggest that an explosive
convergence of ra... 阅读全帖
W*****B
发帖数: 4796
47
印第安老头出来化解矛盾,还把鼓几乎敲到人家学生脸上
Kentucky student seen in viral confrontation with Native American speaks out
The Kentucky high school student seen in a viral video standing-face-to-face
with a Native American protester at a Washington rally spoke out for the
first time Sunday evening, claiming in a statement that he and his
classmates were taunted by a group of African-American protesters and saying
that he and his family had received death threats.
Nick Sandmann, a junior at Covington Catholic High S... 阅读全帖

发帖数: 1
48
Although serum specimens from our case patient were repeatedly negative for
2019-nCoV, viral RNA has been detected in blood in severely ill patients in
China.4 However, extrapulmonary detection of viral RNA does not necessarily
mean that infectious virus is present, and the clinical significance of the
detection of viral RNA outside the respiratory tract is unknown at this time
.

发帖数: 1
49
我找了找,新冠是和一种马来亚穿山甲冠状病毒氨基酸序列97%相同,没找到华南农大
的论文
不过五毒所基本可以洗白了
nCoV-2019 Spike Protein Receptor Binding Domain Shares High Amino Acid
Identity With a Coronavirus Recovered from a Pangolin Viral Metagenomic
Dataset
Novel 2019 coronavirus
nCoV-2019 Evolutionary History
Jan 30
1 / 7
Jan 30
1d ago
torptube
2
7d
An outbreak of respiratory illness caused by a novel coronavirus (nCoV-2019,
NC_045512.2 43) first identified in Wuhan China has resulted in over seven
thousand confirmed cases. So far, the nCoV-20... 阅读全帖

发帖数: 1
50
她提出了一个观点就是control room, 核心思想是如果新冠是自然突变的,而且是这么
明显的突变,那么它会马上启动damage control自毁机制的,不会在自然界中存活长久
她还说美国科学家那篇说新冠是自然起源的文章是受美国政府指使的
https://www.dimsumdaily.hk/czech-molecular-biologist-dr-sona-pekova-explains
-in-layman-terms-that-covid-19-virus-originates-from-a-lab-in-u-s-and-not-
china/
30th March 2020 – (Prague) A Czech molecular biologist, Dr. Soňa Peková
explained in detail why she believed that the novel coronavirus originated
from the laboratory in the U.S. and not in China. She also tried to dis... 阅读全帖
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