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The HIT Center for Life Sciences (HCLS) was founded in 2016, as the first
special academic zone of Harbin Institute of Technology(HIT), which runs its
own graduate program and enjoys unparalleled freedom in research, personnel
employment and financial flexibility within the university. In HCLS,
Principal Investigators (PIs) have gained outstanding achievements on
various disciplines.
Core facilities currently undergoing include: Cryo-Electron Microscopy
Platform, Imaging Platform, Mass Spectrometry Platform, Nuclear Magnetic
Technology Platform, Protein Structure and Biomolecular Interaction Analysis
Platform, Nucleic Acids Analysis Platform, Cell Culture Lab, SPF Laboratory
Animal Room.
HCLS now recruits 3 directors (or vice directors) of core facilities, the
details are as follows:
Director (Vice Director) of
Proteomics Center
Responsibilities
1.Responsible for technical services and daily administrative working of
Mass Spectrometry Platform.
2.Responsible for operation, maintenance and development of mass
spectrometer.
3.Responsible for training work including basic knowledge and principle of
mass spectrometry, sample preparation, data analysis, etc.
4.Familiarity with use, maintenance and development of LTQ Orbitrap Velos, Q
Exactive and other large-scale bio-mass spectrometer, providing high-
quality MS analysis Services to other laboratories at HCLS. Services here
are including molecular weight determination of proteins and peptides,
further analysis and identification, a complex mix of protein samples after
protein identification, protein translational modifications and comparative
quantitative research proteome. As well as the positive development and
improvement of advanced biological mass spectrometry technology, and
effective use of these technologies to basic biological research to help
solve various biological problems.
Qualifications
1.Doctorate degree or above in Analytical Chemistry, Biochemistry, Protein
Chemistry or related areas.
2.Postdoctoral training or experience working in mass spectrum management is
highly preferred.
3.Familiarity with sample preparation and analysis of various mass
spectrometry methods, proficiency in one of the following technical
categories:
1)proteomics: including proteomics methods of intragel enzymolysis,
intrasolution enzymolysis, quantitative proteomics (iTRAQ, SILAC, label free
, etc.), modified proteomics, etc.
2)small molecules: including chromatographic separation and purification, LC
-MS identification of small molecules, quantitative analysis of MRM small
molecules.
3)macromolecules: understanding of the mass spectrometry of polymer and
intact protein, experience in using the technology of ion mobility and H / D
exchange.
Director (Vice Director) of Antibody Center
Responsibilities
1.Responsible for animal immunity, hybridoma cell fusion, antibody screening
by phage antibody library, including panning, primary screening and
identification of monoclonal antibody, etc.
2.Functional analysis of candidate antibody molecules by ELISA and FACS.
3.Responsible for data reorganization and writing experiment report.
Qualifications
1.Doctorate degree or above in Cell Biology, Biochemistry, Immunology or
related areas.
2.More than 2 years’ working experience in construction and screening of
phage antibody library, antibody engineering transformation, humanization,
affinity maturation and other related laboratory work.
3.Working experience in preparation and detection of hybridoma and
monoclonal antibody.
4.Familiarity with antibody screening knowledge and skills, including ELISA,
FACS, etc.
5.Experience in high-throughput screening is highly preferred.
6.Strong communication skill and team cooperation.
Director (Vice Director) of
Imaging Analysis Center
Responsibilities
1.Provide technical support for cell biology and develop equipment and
technology according to the scientific research needs of HCLS.
2.Responsible for daily administrative working of Imaging Analysis Center.
3.Responsible for recruitment and training the technicians of Imaging
Analysis Center.
4.Responsible for regular technical training for researchers and students.
Qualifications
1.Doctorate degree or above in Cell Biology, Optical physics, Microscopy or
related areas.
2.Familiarity with cell biology technology such as confocal microscope and
transmission electron microscope as well as ability to develop equipment and
technology.
3.More than 5 years’ management experience in confocal microscope，
transmission electron microscope and other equipment.
4.Strong communication skill and team cooperation
Compensation and Benefit Package
1.Suitable candidates and final positions will be determined by the actual
ability and level through the review.
2.An internationally competitive salary is provided and determined during
the interview and salary negotiation.
How to apply
Applications as PDF files including a cover letter, a full CV should be sent
to Prof. Zhiwei Huang ([email protected]), and indicate the “ **
application” in the email subject. The application will open until filled.
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