p*******s
发帖数: 17 | 1 从上个月开始，觉得心跳特别快，有时候晚上歇着的时候自己把脉，起码90-100每分钟
。同时也发现 pipet的时候手抖，下楼梯的时候脚斗，其他也没什么，也不觉得累。一
开始以为是很久没锻炼，out of shape，后来持续了两个星期，就跑去看医生。
做了ECG, 心脏本身没问题，当时医生就怀疑要么是甲状腺有问题，要么是贫血，然后
跑去验血。第二天就确诊为甲亢 （hyperthyroidism). 现在在查到底是哪一种。但是
根据我自己的症状，和眼睛感到不适，我觉得基本上就是Graves' disease了。也终于
科普了一把，原来现在只有极少数的人是因为缺碘而患病的，大部分是因为自身免疫系
统有毛病，开始攻击自己的甲状腺了。
想想也挺郁闷的，家里从来没有人得病，就我一个。算中奖了吧，可是买的彩票从来没
中过。ld也有免疫系统的问题，我们两个加起来，真是可以算是中头奖了。我们也都算
是心地善良的人，为什么就这么倒霉呢？
虽然说人总是要得病的，可这也真不是个时候：我正忙着写论文，赶着春天毕业；我们
也打算尽快要个小孩。现在又要把我身体情况，将要吃的药使否对胎儿安全也考虑在里
面,sigh | c********e
发帖数: 496 | 2 I guess the drug that will decrease WBC is PTU, it is pretty safe, just
monitor your CBC regularly, that's all. | p*******s
发帖数: 17 | 3 Thanks.
I don't know why it's so popular here in the US to do the radioactive iodine
uptake. The whole thing just doesn't sound right to me, although I know
that it has been done for a long long time.
【在 c********e 的大作中提到】
: I guess the drug that will decrease WBC is PTU, it is pretty safe, just
: monitor your CBC regularly, that's all.
| c********e
发帖数: 496 | 4 there are radio-labeled iodine related procedures, one is for Dx, safe. and
the other is for therapy, may cause hypothroidism, I supposed what you were
talking about was the latter, right? | y****i
发帖数: 52 | 5 吃药，得甲亢的复发率很高，所以美国人喜欢用radioactive iodio，也不是不无道理
的。其实那个剂量很小，最大的副作用就是得甲低，终身服用甲状腺素，是非常安全的。
吃药的坏处是，对内脏器官有伤害，如肝脏，等。特别你如果要怀孕，就更要小心。用
放射性碘治疗，6个月到1年就可以怀孕。其实放射性碘治疗挺起来可怕，还是挺安全有
效的。
我有个朋友吃药，结果反复复发，非常痛苦，最后还是做了放射性碘治疗。
【在 p*******s 的大作中提到】
: 从上个月开始，觉得心跳特别快，有时候晚上歇着的时候自己把脉，起码90-100每分钟
: 。同时也发现 pipet的时候手抖，下楼梯的时候脚斗，其他也没什么，也不觉得累。一
: 开始以为是很久没锻炼，out of shape，后来持续了两个星期，就跑去看医生。
: 做了ECG, 心脏本身没问题，当时医生就怀疑要么是甲状腺有问题，要么是贫血，然后
: 跑去验血。第二天就确诊为甲亢 （hyperthyroidism). 现在在查到底是哪一种。但是
: 根据我自己的症状，和眼睛感到不适，我觉得基本上就是Graves' disease了。也终于
: 科普了一把，原来现在只有极少数的人是因为缺碘而患病的，大部分是因为自身免疫系
: 统有毛病，开始攻击自己的甲状腺了。
: 想想也挺郁闷的，家里从来没有人得病，就我一个。算中奖了吧，可是买的彩票从来没
: 中过。ld也有免疫系统的问题，我们两个加起来，真是可以算是中头奖了。我们也都算
| p*******s
发帖数: 17 | 6 What's Dx?
and
were
【在 c********e 的大作中提到】
: there are radio-labeled iodine related procedures, one is for Dx, safe. and
: the other is for therapy, may cause hypothroidism, I supposed what you were
: talking about was the latter, right?
| c********e
发帖数: 496 | | p*******s
发帖数: 17 | 8 I got back my antibody results today, and it shows that my TSI (thyroid
stimulating immunoglobulin) is high, thyroid peroxidase antibody is also
high, and thyroid globulin antibody is slghtly higher than normal.
From what I've read, TSI indicates Graves, and the peroxidase antibody
signifies Hashimito's. So do I have both? Which they say is rare but could
happen, and it's called Hashitoxicosis. My doctor (a really nice doctor, but
too bad not an endocrinologist) and I thought doing a Radioactive
【在 c********e 的大作中提到】
: diagnosis
| c********e
发帖数: 496 | 9 OK, first check the titration of the antibodies, antibody positive only
means nothing.
TSI is more specific than peroxidase antibody.
some symptoms like eye's signs are specific in grave's disease.
You can not have both of hashimoto's and grave's, they are totally different
. For grave's, you simple has hyperthyroidism,but hashimoto's, you has
hyperthyroidism first weeks or months, and then hypothyroidism follows. So
iodine reuptake test will tell you which one is the culprit. | p*******s
发帖数: 17 | 10 Thanks for keeping up with me and be interested in answering my posts.
I know it sounds wierd to have both Grave's and Hashimoto's. But there are
medical researchers who think that a lot of these deseases defined by
symptoms, hormone levels or the pesence of antibodies are actually the same
pathological response or caused by similar mechanisms. So hyper- and hypo-,
or Grave's and Hashimoto's can co-exist in one person, but dominate at
different times. Although severe cases are rare, mild cases a
【在 c********e 的大作中提到】
: OK, first check the titration of the antibodies, antibody positive only
: means nothing.
: TSI is more specific than peroxidase antibody.
: some symptoms like eye's signs are specific in grave's disease.
: You can not have both of hashimoto's and grave's, they are totally different
: . For grave's, you simple has hyperthyroidism,but hashimoto's, you has
: hyperthyroidism first weeks or months, and then hypothyroidism follows. So
: iodine reuptake test will tell you which one is the culprit.
| c********e
发帖数: 496 | 11 This is where the physicians and researchers differ.
physician seldom considers the rare case in the literature as one of the
differentials initially, while researcher does.
In your case, as I said, the antibody is not super specific for the Dx of
Hashimoto's.
You have excessive thyroid hormone in your blood for sure, but why?
For grave's, the thyroid gland cell is stimulated by TSI, producing more
hormone, but for Hashimoto's, the inflammation breaks the thyroid gland
cells and release the horm |
|
