s******a 发帖数: 472 | |
P****d 发帖数: 564 | 2 BLAST indeed (and the Karlin-Altschul statistics behind it).
modern synthesis of evolution
Michaelis-Menten kinetics
genetic mapping
crystallography
PubMed
R
image processing (from gel bands to single molecule imaging)
Looking forward, my personal favorite is network motif analysis. |
y**********n 发帖数: 478 | 3 Wide range of cellular interaction networks analysis
Metabolic pathways, gene regulation and cell cycles analysis based on
Kinetic biochemical models
Flux balance analysis of genome-scale metabolic networks
the concept of Robustness in biological system
comparative genomics based on numerous genome projects |
d*******1 发帖数: 854 | 4 到了,米是常数和R也都成了computational biology的成果了?
【在 P****d 的大作中提到】 : BLAST indeed (and the Karlin-Altschul statistics behind it). : modern synthesis of evolution : Michaelis-Menten kinetics : genetic mapping : crystallography : PubMed : R : image processing (from gel bands to single molecule imaging) : Looking forward, my personal favorite is network motif analysis.
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s******a 发帖数: 472 | 5 The application of M-M kinetics in pathway modeling did provide some new
insights or rediscover system properties.
【在 d*******1 的大作中提到】 : 到了,米是常数和R也都成了computational biology的成果了?
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d********m 发帖数: 3662 | 6 the original work of Michaelis-Menten kinetics was a lot more elegant than
so-called computational biology. |
c*********7 发帖数: 148 | 7 crystallography不能算作computational吧。。。感觉,computational bio还没起来
啊。。 |
P****d 发帖数: 564 | 8 What converts the diffraction patterns to structures, then? :)
【在 c*********7 的大作中提到】 : crystallography不能算作computational吧。。。感觉,computational bio还没起来 : 啊。。
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P****d 发帖数: 564 | 9 Hehe, R is provocative. What I meant to say is that statistics would not
the same without biology (eg RA Fisher)
【在 d*******1 的大作中提到】 : 到了,米是常数和R也都成了computational biology的成果了?
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b******y 发帖数: 627 | 10 computation in crystallography is closer to physics than to biology.
"computational biology" (including "system(s) biology" and "mathematics
biology") is indeed a broad and confusing term. |
s******a 发帖数: 472 | 11 2000年NIH定义
http://www.bisti.nih.gov/docs/compubiodef.pdf
Bioinformatics: Research, development, or application of computational tools
and approaches for expanding the use of biological, medical, behavioral or
health data, including those to acquire, store, organize, archive, analyze,
or visualize such data.
Computational Biology: The development and application of data-analytical
and theoretical methods, mathematical modeling and computational simulation
techniques to the study of biological, behavioral, and social systems. |
s******a 发帖数: 472 | 12 "behavioral" "social"
这个似乎太宽泛了
tools
or
,
simulation
【在 s******a 的大作中提到】 : 2000年NIH定义 : http://www.bisti.nih.gov/docs/compubiodef.pdf : Bioinformatics: Research, development, or application of computational tools : and approaches for expanding the use of biological, medical, behavioral or : health data, including those to acquire, store, organize, archive, analyze, : or visualize such data. : Computational Biology: The development and application of data-analytical : and theoretical methods, mathematical modeling and computational simulation : techniques to the study of biological, behavioral, and social systems.
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s******8 发帖数: 2131 | 13 any groups study the connection between genetics and social behaviors?
【在 s******a 的大作中提到】 : "behavioral" "social" : 这个似乎太宽泛了 : : tools : or : , : simulation
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