e*r
发帖数: 103 | 1 Can miRNA or amiRNA regulate translation while not interfere with
trancriptional level? |
X***n
发帖数: 366 | 2 最早的说法就是microRNA只repress translation而不改变transcription level啊。
虽然现在说也会影响转录水平。 |
h********n
发帖数: 4079 | 3 as far as I know, miRNA does not interfere with transcriptional level
directly, but indirectly, anything can happen. |
w******a
发帖数: 1527 | 4 我印象中miRNA因为perfect match与否而作用不同，对不？ |
e*r
发帖数: 103 | 5 那也就是说直接检测转录水平，可能不会改变？但是影响翻译？ |
a***e
发帖数: 1010 | 6 In S. Pombe and A. Thaliana, miRNAs are able to induce histone modification
and heterochromatin formation, which eventually inhibit transcription.
However, it is still controversial whether miRNAs translocate into the
nucleus and inhibit trasncription in metazoans.
It is big leap if you can demonstrate this. |
W****C
发帖数: 1937 | 7 还在讨论啊 不是发过ｐａｐｅｒ说８０％是转录水平嘛 |
