l*******2
发帖数: 1 | 1 你们都看google 新闻呢
说是露露 和 娜娜 这个是意外收获
China’s CRISPR twins might have had their brains inadvertently enhanced
New research suggests that a controversial gene-editing experiment to make
children resistant to HIV may also have enhanced their ability to learn and
form memories. |
l*******2
发帖数: 1 | 2 说把CCR5基因突变掉本来是防御艾滋病 结果没曾想到会然智力发育增强 意外收获 |
w**********g
发帖数: 5486 | |
x********e
发帖数: 35261 | 4 你是千老吗？might这种词都用出来了，这结论能信？
and
【在 l*******2 的大作中提到】
: 你们都看google 新闻呢
: 说是露露 和 娜娜 这个是意外收获
: China’s CRISPR twins might have had their brains inadvertently enhanced
: New research suggests that a controversial gene-editing experiment to make
: children resistant to HIV may also have enhanced their ability to learn and
: form memories.
|
l*******2
发帖数: 1 | 5 真的 今天的google 新闻
The brains of two genetically edited girls born in China last year may have
been changed in ways that enhance cognition and memory, scientists say.
The twins, called Lulu and Nana, reportedly had their genes modified before
birth by a Chinese scientific team using the new editing tool CRISPR. The
goal was to make the girls immune to infection by HIV, the virus that causes
AIDS.
Now, new research shows that the same alteration introduced into the girls’
DNA, deletion of a gene called CCR5, not only makes mice smarter but also
improves human brain recovery after stroke, and could be linked to greater
success in school.
“The answer is likely yes, it did affect their brains,” says Alcino J.
Silva, a neurobiologist at the University of California, Los Angeles, whose
lab uncovered a major new role for the CCR5 gene in memory and the brain’s
ability to form new connections.
“The simplest interpretation is that those mutations will probably have an
impact on cognitive function in the twins,” says Silva. He says the exact
effect on the girls’ cognition is impossible to predict, and “that is why
it should not be done.”
【在 w**********g 的大作中提到】
: 真的假的
|
s********t
发帖数: 199 | |
l*******2
发帖数: 1 | 7 你写discussion部分的时候用不用这个词呢？
【在 x********e 的大作中提到】
: 你是千老吗？might这种词都用出来了，这结论能信？
:
: and
|
l*******2
发帖数: 1 | |
r***i
发帖数: 1 | 9 此帖证实你的确是千老
【在 l*******2 的大作中提到】
: 你写discussion部分的时候用不用这个词呢？
|
w**********g
发帖数: 5486 | 10 这是人类史上标志性重大意义的事件
He made history
[在 lubbock12 (非老非小将) 的大作中提到：]
:真的 今天的google 新闻
:The brains of two genetically edited girls born in China last year may have
been changed in ways that enhance cognition and memory, scientists say.
:The twins, called Lulu and Nana, reportedly had their genes modified before
birth by a Chinese scientific team using the new editing tool CRISPR. The
:goal was to make the girls immune to infection by HIV, the virus that
causes AIDS.
:Now, new research shows that the same alteration introduced into the girls
’ DNA, deletion of a gene called CCR5, not only makes mice smarter but also
:improves human brain recovery after stroke, and could be linked to greater
:success in school.
:“The answer is likely yes, it did affect their brains,” says Alcino J.
:Silva, a neurobiologist at the University of California, Los Angeles, whose
lab uncovered a major new role for the CCR5 gene in memory and the brain’s
ability to form new connections.
:“The simplest interpretation is that those mutations will probably have an
impact on cognitive function in the twins,” says Silva. He says the exact
:.......... |
|
|
x********e
发帖数: 35261 | 11 你想想那两个娃才多大，再想想你读的那篇报道要得出那些结论得做什么实验。动动脑
子。
【在 l*******2 的大作中提到】
: 你写discussion部分的时候用不用这个词呢？
|
l*******2
发帖数: 1 | 12 我早就说过 北有韩春雨 南有贺建奎 都是响当当的好汉
have
before
【在 w**********g 的大作中提到】
: 这是人类史上标志性重大意义的事件
: He made history
: [在 lubbock12 (非老非小将) 的大作中提到：]
: :真的 今天的google 新闻
: :The brains of two genetically edited girls born in China last year may have
: been changed in ways that enhance cognition and memory, scientists say.
: :The twins, called Lulu and Nana, reportedly had their genes modified before
: birth by a Chinese scientific team using the new editing tool CRISPR. The
: :goal was to make the girls immune to infection by HIV, the virus that
: causes AIDS.
|
x*****q
发帖数: 2336 | |
x********e
发帖数: 35261 | 14 那个报道就是挂羊头卖狗肉。说CCR5突变可能有xxx好处。然后蹭基因编辑婴儿的热点
说这两娃有xxx优势。mb这两个娃基因编辑根本就失败了好不好，而且基因编辑的问题
是引入了其他风险。
【在 l*******2 的大作中提到】
: 我早就说过 北有韩春雨 南有贺建奎 都是响当当的好汉
:
: have
: before
|
l*******2
发帖数: 1 | 15 这不是实验 这是case report
【在 x********e 的大作中提到】
: 你想想那两个娃才多大，再想想你读的那篇报道要得出那些结论得做什么实验。动动脑
: 子。
|
x*****q
发帖数: 2336 | 16 下帝
很多惊人的科学发现都是偶然、无心、歪打正着
比如青霉素
【在 x********e 的大作中提到】
: 那个报道就是挂羊头卖狗肉。说CCR5突变可能有xxx好处。然后蹭基因编辑婴儿的热点
: 说这两娃有xxx优势。mb这两个娃基因编辑根本就失败了好不好，而且基因编辑的问题
: 是引入了其他风险。
|
d*****u
发帖数: 17243 | |
s********t
发帖数: 199 | 18 也许就是因为小才能看出来比其他婴儿聪明呗。过几天都能下地跑了可能就显不出来了
。除非三岁就能做奥数了。哈哈哈哈哈
：才多大点啊？这也能看出来大脑发育 |
x****6
发帖数: 4339 | 19 尼玛，在老鼠身上发现可以帮助中风恢复 就说能帮助人类智力。
生物千老真是太low了。 |
s********t
发帖数: 199 | 20 这个文章是MIT的嘛？下面落款MIT TECH REVIEW
：那个报道就是挂羊头卖狗肉。说CCR5突变可能有xxx好处。然后蹭基因编辑婴儿的热点
：说这两娃有xxx优势。mb这两个娃基因编辑根本就失败了好不好，而且基因编辑的问题 |
|
|
l*******2
发帖数: 1 | 21 贺建奎已经甩开老美单独干了，
美国人现在急眼了 怕发现CCR5突变对大脑发育这个重要发现没有自己的位置 纷纷表示
自己在小鼠上已经做出了结果，贺建奎是他们的follower,
还要点儿碧莲吗，
The Chinese team, led by He Jiankui of the Southern University of Science
and Technology in Shenzhen, claimed it used CRISPR to delete CCR5 from human
embryos, some of which were later used to create pregnancies. HIV requires
the CCR5 gene to enter human blood cells.
The experiment has been widely condemned as irresponsible, and He is under
investigation in China. News of the first gene-edited babies also inflamed
speculation about whether CRISPR technology could one day be used to create
super-intelligent humans, perhaps as part of a biotechnology race between
the US and China.
There is no evidence that He actually set out to modify the twins’
intelligence. MIT Technology Review contacted scientists studying the
effects of CCR5 on cognition, and they say the Chinese scientist never
reached out to them, as he did to others from whom he hoped to get
scientific advice or support.
“As far as I know, we never heard from him,” says Miou Zhou, a professor
at the Western University of Health Sciences in California.
Although He never consulted the brain researchers, the Chinese scientist was
certainly aware of the link between CCR5 and cognition. It was first shown
in 2016 by Zhou and Silva, who found that removing the gene from mice
significantly improved their memory. The team had looked at more than 140
different genetic alterations to find which made mice smarter.
Silva says because of his research, he sometimes interacts with figures in
Silicon Valley and elsewhere who have, in his opinion, an unhealthy interest
in designer babies with better brains. That’s why, when the birth of the
twins became public on November 25, Silva says he immediately wondered if it
had been an attempt at this kind of alteration. “I suddenly realized—Oh,
holy shit, they are really serious about this bullshit,” says Silva. “My
reaction was visceral repulsion and sadness.”
During a summit of gene editing scientists that occurred two days later in
Hong Kong, He acknowledged he had known all along about the potential brain
effects from the UCLA research. “I saw that paper, it needs more
independent verification,” He replied when asked about it during a Q&A
session (see video here). He added: “I am against using genome editing for
enhancement.”
Whatever He’s true aims, evidence continues to build that CCR5 plays a
major role in the brain. Today, for example, Silva and a large team from the
US and Israel say they have new proof that CCR5 acts as a suppressor of
memories and synaptic connections.
According to their new report, appearing in the journal Cell, people who
naturally lack CCR5 recover more quickly from strokes. What’s more, people
missing at least one copy of the gene seem to go further in school,
suggesting a possible role in everyday intelligence.
“We are the first to report a function of CCR5 in the human brain, and the
first to report a higher level of education,” says UCLA biologist S. Thomas
Carmichael, who led the new study. He calls the link to educational success
“tantalizing” but says it needs further study.
The discoveries about CCR5 are already being followed up in drug trials on
both stroke patients and people with HIV, who sometimes suffer memory
problems. In those studies, one of which is under way at UCLA, people are
being given an anti-HIV drug, Maraviroc, which chemically blocks CCR5, to
see if it improves their cognition.
Silva says there is a big difference between trying to correct deficits in
such patients and trying to create enhancement. “Cognitive problems are one
of the biggest unmet needs in medicine. We need drugs, but it’s another
thing to take normal people and muck with the DNA or chemistry to improve
them,” he says. “We simply don’t know enough to do it. Nature has struck
a very fine balance.”
Just because we shouldn’t alter normal intelligence doesn’t mean we can’t
. Silva says the genetic manipulations used to make “smart mice” show not
only that it is possible, but that changing CCR5 has particularly big
effects.
“Could it be conceivable that at one point in the future we could increase
the average IQ of the population? I would not be a scientist if I said no.
The work in mice demonstrates the answer may be yes,” he says. “But mice
are not people. We simply don’t know what the consequences will be in
mucking around. We are not ready for it yet.”
【在 x********e 的大作中提到】
: 那个报道就是挂羊头卖狗肉。说CCR5突变可能有xxx好处。然后蹭基因编辑婴儿的热点
: 说这两娃有xxx优势。mb这两个娃基因编辑根本就失败了好不好，而且基因编辑的问题
: 是引入了其他风险。
|
l*******2
发帖数: 1 | 22 你没看出来吗，这是老美在抢credit
【在 x****6 的大作中提到】
: 尼玛，在老鼠身上发现可以帮助中风恢复 就说能帮助人类智力。
: 生物千老真是太low了。
|
x********e
发帖数: 35261 | 23 你仔细看是什么人在哪里用什么做的实验。case个屁啊
【在 l*******2 的大作中提到】
: 这不是实验 这是case report
|
l*******2
发帖数: 1 | 24 那人做临床试验的都可以看成case report, cohort, case-control 这些都是
【在 x********e 的大作中提到】
: 你仔细看是什么人在哪里用什么做的实验。case个屁啊
|
x********e
发帖数: 35261 | 25 问题是贺的婴儿到现在都没有证明编辑成功，一个ucla的千老能远程下结论扯到基因编
辑婴儿？
【在 l*******2 的大作中提到】
: 那人做临床试验的都可以看成case report, cohort, case-control 这些都是
|
xt
发帖数: 17532 | 26 很难说，现在说不定已经学到复变函数了
【在 x********e 的大作中提到】
: 你想想那两个娃才多大，再想想你读的那篇报道要得出那些结论得做什么实验。动动脑
: 子。
|
l*******2
发帖数: 1 | 27 你定义这项科学研究就是用编辑成功和编辑不成功作为标准吗？你还是回家抱孩子去吧
【在 x********e 的大作中提到】
: 问题是贺的婴儿到现在都没有证明编辑成功，一个ucla的千老能远程下结论扯到基因编
: 辑婴儿？
|
x********e
发帖数: 35261 | 28 你抬头看你的标题。老将真的是脑子进屎没法讨论。
【在 l*******2 的大作中提到】
: 你定义这项科学研究就是用编辑成功和编辑不成功作为标准吗？你还是回家抱孩子去吧
|
l*******2
发帖数: 1 | 29 这帖子里老将是谁啊 让我先看看
【在 x********e 的大作中提到】
: 你抬头看你的标题。老将真的是脑子进屎没法讨论。
|
g********0
发帖数: 6201 | 30 如果大脑发育优于常人才真的可怕！
以后穷人还有什么资本和富人竞争？
如果你不幸是个穷人的话，你愿意你的子孙世世代代为奴吗？ |
|
|
l****t
发帖数: 36289 | 31 估计是已经自己能冲奶粉了
【在 d*****u 的大作中提到】
: 才多大点啊？这也能看出来大脑发育
|
b*******8
发帖数: 37364 | 32 其实本来就是国家秘密搞的提高智商实验 伪装成治病
and
★ 发自iPhone App: ChinaWeb 1.1.5
【在 l*******2 的大作中提到】
: 你们都看google 新闻呢
: 说是露露 和 娜娜 这个是意外收获
: China’s CRISPR twins might have had their brains inadvertently enhanced
: New research suggests that a controversial gene-editing experiment to make
: children resistant to HIV may also have enhanced their ability to learn and
: form memories.
|
T***u
发帖数: 1468 | |
c*****e
发帖数: 737 | 34 说失败的都是民科, 没有正经读过生物学博士
【在 x********e 的大作中提到】
: 那个报道就是挂羊头卖狗肉。说CCR5突变可能有xxx好处。然后蹭基因编辑婴儿的热点
: 说这两娃有xxx优势。mb这两个娃基因编辑根本就失败了好不好，而且基因编辑的问题
: 是引入了其他风险。
|
m*********9
发帖数: 56 | 35 这个基因只是跟老年痴呆有点关系，与聪明还差的远。
再说了，这基因也许有别的好作用。什么都不知道就用人做，没事还好，要是残废，小
孩不得恨死父母和这家伙
and
【在 l*******2 的大作中提到】
: 你们都看google 新闻呢
: 说是露露 和 娜娜 这个是意外收获
: China’s CRISPR twins might have had their brains inadvertently enhanced
: New research suggests that a controversial gene-editing experiment to make
: children resistant to HIV may also have enhanced their ability to learn and
: form memories.
|
l******t
发帖数: 55733 | |
C*****l
发帖数: 1 | 37 对，要能看出来真牛鼻，至少要到5-6岁
【在 x********e 的大作中提到】
: 你想想那两个娃才多大，再想想你读的那篇报道要得出那些结论得做什么实验。动动脑
: 子。
|
c*****8
发帖数: 496 | 38 个人感觉不太靠谱，老鼠实验跟人能一样吗，再说智能内在机理十分复杂，并非随便敲
掉一个基因就能增强的，俺反而更担心俩小孩未来的健康风险问题。 |
B*Q
发帖数: 25729 | |
n****O
发帖数: 1 | 40 这是人类史上标志性重大意义的事件
He made history
[在 lubbock12 (非老非小将) 的大作中提到：]
:真的 今天的google 新闻
:The brains of two genetically edited girls born in China last year may have
been changed in ways that enhance cognition and memory, scientists say.
:The twins, called Lulu and Nana, reportedly had their genes modified before
birth by a Chinese scientific team using the new editing tool CRISPR. The
:goal was to make the girls immune to infection by HIV, the virus that
causes AIDS.
:Now, new research shows that the same alteration introduced into the girls
’ DNA, deletion of a gene called CCR5, not only makes mice smarter but also
:improves human brain recovery after stroke, and could be linked to greater
:success in school.
:“The answer is likely yes, it did affect their brains,” says Alcino J.
:Silva, a neurobiologist at the University of California, Los Angeles, whose
lab uncovered a major new role for the CCR5 gene in memory and the brain’s
ability to form new connections.
:“The simplest interpretation is that those mutations will probably have an
impact on cognitive function in the twins,” says Silva. He says the exact
:..........
----------------
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音乐专辑版块:
https://www.reddit.com/r/AlbumCN/
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https://www.reddit.com/r/MovieMultiLang
成人视频版块:
https://www.reddit.com/r/adultVideo/ |
|
|
m*****n
发帖数: 3575 | |
