e*****t
发帖数: 642 | 1 seems to have huge debate on this. newbie on stem cells. any comments
welcomed. |
O******e
发帖数: 4845 | 2 几年内是不可能替代的。
【在 e*****t 的大作中提到】
: seems to have huge debate on this. newbie on stem cells. any comments
: welcomed.
|
G******O
发帖数: 189 | 3 现在两者不同的证据越来越多。已经不象几年前那么乐观了。
【在 e*****t 的大作中提到】
: seems to have huge debate on this. newbie on stem cells. any comments
: welcomed.
|
G**d
发帖数: 733 | 4 re
【在 O******e 的大作中提到】
: 几年内是不可能替代的。
|
e*****t
发帖数: 642 | 5 any clinical trials going on? on still on bench?
iPS could lead to cancer. that's deadly.
【在 G******O 的大作中提到】
: 现在两者不同的证据越来越多。已经不象几年前那么乐观了。
|
n*********b
发帖数: 140 | 6 "iPSCs is a cancer without any cancer-causing mutation"-God said. |
e*****t
发帖数: 642 | 7 haha, god is right, epigenetics make them cancer, not mutation.
【在 n*********b 的大作中提到】
: "iPSCs is a cancer without any cancer-causing mutation"-God said.
|
O******e
发帖数: 4845 | 8 这上帝的英语不过关啊，^_^
【在 n*********b 的大作中提到】
: "iPSCs is a cancer without any cancer-causing mutation"-God said.
|
V**F
发帖数: 164 | 9 haha
【在 O******e 的大作中提到】
: 这上帝的英语不过关啊，^_^
|
s*****y
发帖数: 32 | 10 永远也不可能代替的。iPS细胞明显实用一些。但ES细胞毕竟是真正的胚胎干细胞，也
不会像iPS一像有各种epigenetic memory之类。iPS和ES都离临床太遥远。未分化细胞
的致瘤性总是个大问题。转分化倒是挺有希望
【在 e*****t 的大作中提到】
: seems to have huge debate on this. newbie on stem cells. any comments
: welcomed.
|
|
|
O******e
发帖数: 4845 | 11 “永远也不可能”的结论，往往都是错的，呵呵
【在 s*****y 的大作中提到】
: 永远也不可能代替的。iPS细胞明显实用一些。但ES细胞毕竟是真正的胚胎干细胞，也
: 不会像iPS一像有各种epigenetic memory之类。iPS和ES都离临床太遥远。未分化细胞
: 的致瘤性总是个大问题。转分化倒是挺有希望
|
n********k
发帖数: 2818 | 12 well, it might happen to be a right one...thinking about those disease model
using human cells...BTW, what's ES and what's the usage? anyone remind me:)
))...the same questions with iPS?...hype or hope?
【在 O******e 的大作中提到】
: “永远也不可能”的结论，往往都是错的，呵呵
|
y******8
发帖数: 1764 | 13 For iPS, you might get a cell line from the patient with or without known
mutation, and differentiate it into the disease-related tissue.
Then play with it and call it the disease model. The significance is you
might be able to set up hundreds of lines based on iPS techniques.
model
【在 n********k 的大作中提到】
: well, it might happen to be a right one...thinking about those disease model
: using human cells...BTW, what's ES and what's the usage? anyone remind me:)
: ))...the same questions with iPS?...hype or hope?
|
n********k
发帖数: 2818 | 14 Sure, I am with you...I was just reminding onco of those...but still both ES
and iPS for cure are hype, agree? But I am not underestimating the value
of iPS in research etc...It is huge and Shinya definitely deserves Nobel...
【在 y******8 的大作中提到】
: For iPS, you might get a cell line from the patient with or without known
: mutation, and differentiate it into the disease-related tissue.
: Then play with it and call it the disease model. The significance is you
: might be able to set up hundreds of lines based on iPS techniques.
:
: model
|
o**4
发帖数: 35028 | |
p*******r
发帖数: 4048 | 16 Not in the near future. People now find iPS is really not like ES. Some find
it can turn into cancer.
I think many things need to be sorted out in the next few years.
【在 e*****t 的大作中提到】
: seems to have huge debate on this. newbie on stem cells. any comments
: welcomed.
|
p*******r
发帖数: 4048 | 17 Agreed. I think we should differentiate ES or iPS outside of body into a
organ, then transplant it in.
ES
【在 n********k 的大作中提到】
: Sure, I am with you...I was just reminding onco of those...but still both ES
: and iPS for cure are hype, agree? But I am not underestimating the value
: of iPS in research etc...It is huge and Shinya definitely deserves Nobel...
|
p*****m
发帖数: 7030 | 18 河马 你那天不是说讨论feeding/obesity来着？你信箱满了 啥时候聊下？
Agreed. I think we should differentiate ES or iPS outside of body into a
organ, then transplant it in.
ES
【在 p*******r 的大作中提到】
: Agreed. I think we should differentiate ES or iPS outside of body into a
: organ, then transplant it in.
:
: ES
|
n********k
发帖数: 2818 | 19 I c, just message him through his box... maybe I shall shoot him an email
too
【在 p*****m 的大作中提到】
: 河马 你那天不是说讨论feeding/obesity来着？你信箱满了 啥时候聊下？
:
: Agreed. I think we should differentiate ES or iPS outside of body into a
: organ, then transplant it in.
: ES
|
n********k
发帖数: 2818 | 20 This is a dream in near future and it really takes a lot, A LOT...maybe some
simpler organs, say joints, or liver?
【在 p*******r 的大作中提到】
: Agreed. I think we should differentiate ES or iPS outside of body into a
: organ, then transplant it in.
:
: ES
|
|
|
j*b
发帖数: 341 | 21 Do we find anything new using these disease model?
Majority of the paper only claimed that they found similar phenotypes
reported in mouse model.
【在 y******8 的大作中提到】
: For iPS, you might get a cell line from the patient with or without known
: mutation, and differentiate it into the disease-related tissue.
: Then play with it and call it the disease model. The significance is you
: might be able to set up hundreds of lines based on iPS techniques.
:
: model
|
s******s
发帖数: 13035 | 22 因为刚开始做啊。可以做drug screen啊，比mouse model强多了吧
【在 j*b 的大作中提到】
: Do we find anything new using these disease model?
: Majority of the paper only claimed that they found similar phenotypes
: reported in mouse model.
|
j*b
发帖数: 341 | 23 even if they were the same, there are still tons of problems.The in vitro
differentiation is actually not reliable. A lot of variations,people only
report the good but hide the bad.
【在 G******O 的大作中提到】
: 现在两者不同的证据越来越多。已经不象几年前那么乐观了。
|
n********k
发帖数: 2818 | 24 Sure...nothing is perfect..., Could you let me know what would be a better
alternative when studying the majority of human diseases? ...wish we could
go back to Nazi time, do you?
【在 j*b 的大作中提到】
: even if they were the same, there are still tons of problems.The in vitro
: differentiation is actually not reliable. A lot of variations,people only
: report the good but hide the bad.
|
