c*****t
发帖数: 1084 | 1 question 1 pretty much answers itself. if the proteolytic frag
functions at the transcription level it may occupy its own
promoter binding region (most likely enhancer region) to prevent
transcription complex binding or it can function as dominant
negative to bind an essential, specific positive regulator for
its transcription. if it functions at the post transcription
level several differnt pathways may be involved such as
translationl inhibition, degradation of the protein, degradation
of the |
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