l******e
发帖数: 12192 | 1 non-blocking send/recv + select + multithreading
group
ther |
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c**d
发帖数: 261 | 2 ther are some old posts talk about it |
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i**p
发帖数: 902 | 3 How can I get rid of this virus? I have tried Spybot, Ad Aware and
SpywareBlaster but it keeps coming back. It leaves a shortcut on my desktop
with the name fethard_too and in the C drive it is 124425.exe
Is ther ANY way to get rid of it? Does anybody have any ideas?
Thank you |
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p****t
发帖数: 34 | 4 I need to change my hairstyle.
Is ther any webste to download the free software? |
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j*****y
发帖数: 2 | 5
That's not something important. You see, the OS FreeBSD is an open source
system, programmer in Yahoo can modify the codes to fit ther Site.
FreeBSD is a good OS. But it's not an OS for beginner. It's a the most
UNIX-like one in the *nix searial OS's. If you have not too much experience
in using *nix OS, I suggest you to learn Linux at first. |
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v**n
发帖数: 130 | 6 your goal is to get something different to do, so I would approach it
slightly differently:
0. do your research and find out what are some of ther areas in your company
that may be able to use someone like you. some high profile projects will
do as well.this is the key of your success. once you have one or two area in
mind, then you are ready to move to the next step. - THE MOST IMPORTANT
STEP
1. set up 1-1 with your boss and start with something like "I have been
doing AAA for xxx years.... fee... 阅读全帖 |
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d*****r
发帖数: 2583 | 7 发信人: lazzyman (zzzzzz), 信区: LifeScience
标 题: IF2002 Top201-300
发信站: BBS 水木清华站 (Wed Jun 18 14:39:37 2003), 转信
Rank Abbreviated Journal Title
ISSN
2002 Total Cites
Impact Factor
Immediacy Index
2002 Articles
Cited Half-life
201 PHARMACOL THERAPEUT
0163-7258 5091 5.630 0.419 62 7.1
202 NEUROIMAGE
1053-8119 5752 5.624 0.537 356 3.4
203 GENE THER
0969-7128 7775 5.616 0.541 222 3.6
204 REV PHYSIOL BIOCH P
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y***x
发帖数: 94 | 8 J Pharmacol Exp Ther. 2009 Oct;331(1):265-76. Epub 2009 Jul 23.
Molecular basis for the selectivity of the mammalian bombesin peptide,
neuromedin B, for its receptor.
González N, Nakagawa T, Mantey SA, Sancho V, Uehara H, Katsuno T, Jensen RT.
Digestive Diseases Branch, NIDDK, NIH, Bethesda, MD 20892-1804, USA.
w****[email protected]
thank you so much! |
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a******u
发帖数: 211 | 9 1. Int Arch Allergy Appl Immunol. 1982;68(4):377-81.
Chitin: an immunological adjuvant and a polyclonal B-lymphocyte activator.
Diamantstein T, Klos M, Osawa H, Chen ZC.
2. Arch Immunol Ther Exp (Warsz). 1991;39(1-2):127-32.
Immunoadjuvant properties of chitosan.
Marcinkiewicz J, Polewska A, Knapczyk J.
Please send the papers to e*********[email protected]
Thanks so much!!!! |
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p**i
发帖数: 3525 | 10 这样的例子估计非常多
例如Hh和Cancer的关系:
Cancer Biol Ther. 2004 Feb;3(2):165-6. Epub 2004 Feb 1.
Targeting Sonic Hedgehog: a new way to mow down pancreatic cancer? |
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i***e
发帖数: 1481 | 11 Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic
targets in solid tumors.
Expert Opin Ther Targets. 2010 Sep 1. [Epub ahead of print]
Linger RM, Keating AK, Earp HS, Graham DK.
PMID: 20809868
Please e-mail paper to i*******[email protected]
Thanks a million!!! |
|
n***3
发帖数: 663 | 12 Expert Opin Ther Targets. 2010 Sep;14(9):973-88.
TRPM2 channel properties, functions and therapeutic potentials.
Jiang LH, Yang W, Zou J, Beech DJ.
Please send the paper to e*********[email protected]
Thanks! |
|
g*****i
发帖数: 2537 | 13 Expert Opin Ther Pat. 2010 Feb;20(2):193-212.
Pim kinase inhibitors: a survey of the patent literature.
Morwick T.
Boehringer Ingelheim Pharmaceuticals, Department of Medicinal Chemistry, Inc
., 900 Ridgebury Rd. Ridgefield, CT 06801-0368, USA. t******[email protected]
-ingelheim.com |
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n***3
发帖数: 663 | 14 学校没有这几个journal的access,希望大家帮忙找一下下面的几篇paper:
（PLEASE send the papers to e*********[email protected])
1. Crit Rev Ther Drug Carrier Syst. 1998;15(1):57-88.
The interaction of liposomes with the complement system.
Szebeni J.
2. J Liposome Res. 2008;18(3):195-209.
Liposome-mediated triggering of complement cascade.
Moghimi SM, Hamad I.
3. J Biomed Nanotechnol. 2009 Aug;5(4):364-72.
Complement: alive and kicking nanomedicines.
Andersen AJ, Hashemi SH, Andresen TL, Hunter AC, Moghimi SM.
4. Protein Cell. 201... 阅读全帖 |
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n***3
发帖数: 663 | 15 1. Pharm Res. 2002 Jun;19(6):715-28.
Recent advances in vaccine adjuvants.
Singh M, O'Hagan DT.
2.Drug Discov Today. 2003 Oct 15;8(20):934-43.
Vaccine adjuvants: role and mechanisms of action in vaccine
immunogenicity.
Marciani DJ.
3.Expert Opin Ther Pat. 2010 May;20(5):661-79.
Recent advances in mucosal delivery of vaccines: role of
mucoadhesive/biodegradable polymeric carriers.
Mishra N, Goyal AK, Tiwari S, Paliwal R, Paliwal SR, Vaidya B, Mangal S,
Gupta M, Dube D, Mehta A, Vyas SP.
请把paper发到... 阅读全帖 |
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i***e
发帖数: 1481 | 16 Expert Opin Ther Targets. 2010 Oct;14(10):1073-90.
Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic
targets in solid tumors.
Linger RM, Keating AK, Earp HS, Graham DK.
please email pdf to i*******[email protected]
thanks a lot. |
|
n***3
发帖数: 663 | 17 1. Expert Rev Anticancer Ther. 2008 Apr;8(4):561-72.
Immune cells in colorectal cancer: prognostic relevance and therapeutic
strategies.
Atreya I, Neurath MF.
2.Front Biosci. 2002 Oct 1;7:d2058-71.
HPV innate immunity.
Woodworth CD.
Please send the papers to e*********[email protected]
Thanks ! |
|
n***3
发帖数: 663 | 18 Mol Ther. 2010 Jul;18(7):1379-88. Epub 2010 May 4.
FimH can directly activate human and murine natural killer cells via TLR4.
Mian MF, Lauzon NM, Andrews DW, Lichty BD, Ashkar AA.
Please send the paper to e*********[email protected]
Thanks a lot! |
|
x***o
发帖数: 52 | 19 Expert Rev Cardiovasc Ther. 2008 Jul;6(6):859-72.
Role of postprandial hyperglycemia in cardiovascular disease.
email:
m*********[email protected]
Thanks! |
|
k******2
发帖数: 81 | 20 Targeting autophagy during cancer therapy to improve clinical outcomes.
Levy JM, Thorburn A.
Pharmacol Ther. 2011 Jul;131(1):130-41. Epub 2011 Mar 23.
Please send to k********[email protected]
THANKS. |
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a*****s
发帖数: 838 | 21 Hi, please help, thansk a lot! please email to z*****[email protected]
P. Fender, Gene Ther. Mol. Biol. 8 (2004), p. 85. |
|
y****i
发帖数: 455 | 22 The role of p21 in regulating mammalian regeneration.
Arthur LM, Heber-Katz E.
Stem Cell Res Ther. 2011 Jun 29;2(3):30. [Epub ahead of print]
PMID:21722344[PubMed - as supplied by publisher]
Thanks,
Please email: y****[email protected] |
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j*****d
发帖数: 787 | 23 two friends, ther are neighbors, hehe, have lost $10, 000 BEFORE the collaps
last Friday and Monday. I don't know if they are still in Stocks. |
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j*****d
发帖数: 787 | 24 two friends, ther are neighbors, hehe, have lost $10, 000 BEFORE the collaps
last Friday and Monday. I don't know if they are still in Stocks. |
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a********k
发帖数: 2273 | 25 花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
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g****y
发帖数: 101 | 26 To Carwash: Thank you very much for comment
I can't agree more with you about the low efficiency in infecting the T
cells in vivo with virus. That is why I mentioned the potential problem 4(
AAV载体的靶向问题).
As you suggested, we could modify the virus caspid, for example, mutate the
liver cell recognition sequence and express a chimeric protein combining the
AAV capsid protein and the T cell ligand so that we can increase the
infection efficiency in T cells.
Do you think this approach works?
Here ar... 阅读全帖 |
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a**s
发帖数: 177 | 27 Nat Biotechnol. 2006 Dec;24(12):1558-64
Gene Ther. 2009 Oct;16(10):1189-201.
my email address is: h********[email protected]
thanks. |
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F*Q
发帖数: 3259 | 28 The most impoirtant discoveried are always thought out by several persons at
ther same time? It may not be true.
In my case, I was the first one to report the discovery with solid data.
Somebody may try to scoop it. But the audience of my talk know who are the
first discoverer. None of the senior professors in my field who listened to
my talk and whom I discussed with mentioned anybody else who did this.
soon
it |
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l**********1
发帖数: 5204 | 30 En
温习一下 其十一年前的豪言 啊
中国科学：显著的发展和严峻的挑战
——历史演变和现状比较
于2001年12月4日 1st version
饶毅
本文在简要回顾中国科学史的基础上，介绍一些近年研究的内容，肯定中国
科学令人乐观的进步，并讨论可能的意义。同时也指出，中国优秀论文总量仍不
到世界的百分之一，低于中国经济在世界所占的百分比、也不能适应中国持续发
展的要求。中国科学的规模需要相当程度的扩大、质量有待进一步提高。中国科
技还存在面临许多问题和挑战。
中国科学历史上的优秀例子
一个国家科学研究状况可以近似地由发表论文的情况所反映。以下，本文主
要从生命科学的研究来讨论中国科学的情况，一方面这是我有一定判断力的领域，
另一方面生命科学是科学技术最重要的组成部分之一，可以反映科学主流。讨论
中国论文发表情况前，先谈两个背景：中国科学的历史情况，优秀科学和著名杂
志的关系。
奠定中国生命科学研究是二、三十年代协和医学院生理系林可胜和生化系吴
宪。他们不仅自己研究出色，而且培养和带领了其他研究者。林可胜在胃肠道生
理和神经生理有优秀工作。1942年，他在中国当选为美国科学院外籍院士，是... 阅读全帖 |
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C********4
发帖数: 308 | 31 假如下面的文章都是同一个人发表的。
请问在这个领域算是上等，还是中等，还是比较差的？
＝＝＝＝＝＝＝＝
1.
Metallic gold slows disease progression, reduces cell death and induces
astrogliosis while simultaneously increasing stem cell responses in an EAE
rat model of multiple sclerosis.
Pedersen DS, Fredericia PM, Pedersen MO, Stoltenberg M, Penkowa M, Danscher
G, Rungby J, Larsen A.
Histochem Cell Biol. 2012 Jul 22. [Epub ahead of print]
2.
Metallic silver fragments cause massive tissue loss in the mouse brain.
Locht LJ, Pedersen MØ, Markhol... 阅读全帖 |
|
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S**********e
发帖数: 1789 | 33 给你看看我们系刚进来的助理教授
Vanderbilt University School of Medicine
Fingleton, Barbara Mary , Ph.D. Assistant Professor of Cancer Biology
Publications
Barrett, CW, Fingleton, B, Williams, A, Ning, W, Fischer, MA, Washington, MK
, Chaturvedi, R, Wilson, KT, Hiebert, SW, Williams, CS. MTGR1 is required
for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model.
Cancer Res, 71(4), 1302-12, 2011.
Koon, HB, Fingleton, B, Lee, JY, Geyer, JT, Cesarman, E, Parise, RA, Egorin,
MJ, Dezube, BJ... 阅读全帖 |
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p****n
发帖数: 9263 | 34 Pubmed ID: 19679620
Integr Cancer Ther. 2009 Jun;8(2):123-9.
Feasibility trial of electroacupuncture for aromatase inhibitor--related
arthralgia in breast cancer survivors.
my email: p****[email protected]
奉上蟹黄包感谢 |
|
n***3
发帖数: 663 | 35 1. Expert Opin Ther Targets. 2005 Aug;9(4):753-68.
The insulin-like growth factor-I receptor as a target for cancer therapy.
Baserga R.
2. Cytokine Growth Factor Rev. 2005 Aug-Oct;16(4-5):407-20.
The role of the growth hormone/insulin-like growth factor axis in tumor
growth and progression: Lessons from animal models.
Please send the papers to e*********[email protected]
Thanks so much! |
|
f********h
发帖数: 183 | 36 Can anybody help me find this paper:
Di Giovanni S.
Molecular targets for axon regeneration: focus on the intrinsic pathways.
Expert Opin Ther Targets. 2009 Dec;13(12):1387-98.
If possible, please send a copy to: y****[email protected]
Thanks very much. |
|
m****e
发帖数: 489 | 37 Mol Diagn Ther. 2011 Feb 1;15(1):53-5. doi: 10.2165/11534880-000000000-00000.
Personalized medicine--trends in molecular diagnostics: exponential growth
expected in the next ten years.
Hoggatt J.
Improving the power of diagnostics in the era of targeted therapy and
personalized healthcare.
Walk EE.
Curr Opin Drug Discov Devel. 2010 Mar;13(2):226-34. Review.
Please send to A********[email protected]. Many thanks!! |
|
n***3
发帖数: 663 | 38 Mol Ther. 2013 Jun;21(6):1169-81. doi: 10.1038/mt.2013.55. Epub 2013 Apr 9.
Liposome Delivery of MicroRNA-145 to Mesenchymal Stem Cells Leads to
Immunological Off-target Effects Mediated by RIG-I.
Please send the paper to e*********[email protected]
Thanks so much!!! |
|
T**********1
发帖数: 2406 | 39 When you get from point A to point B, ther was suppose to be something in
between. The missing link is a form of physical that is the hard part.
Yes we humans can use tools, yes we can run and keep balance. But those in
between?
Ac
ph |
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j***s
发帖数: 42 | 40 DEV CELL 12.861
J CLIN INVEST 12.812
PLOS BIOL 12.690
CELL HOST MICROBE 12.609
GENE DEV 12.444
AUTOPHAGY 12.042
NAT STRUCT MOL BIOL 11.902
J CELL BIOL 10.822
SCI TRANSL MED 10.757
CELL RES 10.526
NAT COMMUN 10.015
EMBO J 9.822
P NATL ACAD SCI USA 9.737
CURR BIOL 9.494
PLOS GENET 8.517
PLOS PATHOG 8.136
EMBO MOL MED 7.795
HUM MOL GENET 7.692
SCI SIGNAL 7... 阅读全帖 |
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k****s
发帖数: 1209 | 41 原文在
http://www.skizit.biz/2013/07/21/ecdysone-insect-hormone-an-ind
Ecdysone Insect Hormone Switches on Disease
21 Jul 2013 | ECDYSONE
MORGELLONS:
INSECT HORMONE ECDYSONE TRIGGERS GENETIC CHANGES
TO BUILD NEW HAIR, SKIN, NAILS and CAUSE DISEASES
SkizitGesture-2013
Morgellons is a military grade entomological terror weapon being used to
torture and kill innocent civilians. The medical community has not been
informed about this disease and its complexity keeps it from being properly
identified, ... 阅读全帖 |
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n***3
发帖数: 663 | 42 Expert Opin Ther Targets. 2013 Aug;17(8):863-7. doi: 10.1517/14728222.2013.
816287. Epub 2013 Jul 6.
ADAMTS7: a promising new therapeutic target in coronary heart disease.
Please send the paper to e*********[email protected]
thanks so much! |
|
c**l
发帖数: 121 | 43 非常感谢，email是 l******[email protected]
Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
Deval E, Gasull X, Noël J, Salinas M, Baron A, Diochot S, Lingueglia E.
Pharmacol Ther.2010 Dec;128(3):549-58.
Pharmacology of ASIC channels
Eric Lingueglia,Michel Lazdunski
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling
Volume 2, Issue 4, pages 155–171, July/August 2013 |
|
w*****t
发帖数: 179 | 44 Curr Gene Ther. 2011 Oct;11(5):350-62.
Integrase-defective lentiviral vectors--a stage for nonviral integration
machineries.
Staunstrup NH1, Mikkelsen JG.
Please send my emaill address: w************[email protected]
I appreciate it. |
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s********z
发帖数: 5411 | 45 this is essentially a fast PCR, Right?
the problem is that you have to know what you are looking for and you can't
target many pathogens at the same time.
on ther other hand, NGS offers hypothesis free and precise targeting to
virtually any pathogen.
as
Multiple
to
and |
|
s*****g
发帖数: 87 | 46 Hum Gene Ther. 2001 Oct 10;12(15):1893-905.
Systematic determination of the packaging limit of lentiviral vectors.
Kumar M1, Keller B, Makalou N, Sutton RE.
PMID: 11589831
Please send to [email protected]
(function(){try{var s,a,i,j,r,c,l,b=document.getElementsByTagName("script");l=b[b.length-1].previousSibling;a=l.getAttribute('data-cfemail');if(a){s='';r=parseInt(a.substr(0,2),16);for(j=2;a.length-j;j+=2){c=parseInt(a.substr(j,2),16)^r;s+=String.fromCharCode(c);}s=document.createTextNode(s);l.... 阅读全帖 |
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x**4
发帖数: 112 | 47 http://www.ncbi.nlm.nih.gov/pubmed/24308293
New developments in the use of gene therapy to treat Duchenne muscular
dystrophy.
Jarmin S1, Kymalainen H, Popplewell L, Dickson G.
Expert Opin Biol Ther. 2014 Feb;14(2):209-30. doi: 10.1517/14712598.2014.
866087. Epub 2013 Dec 6.
Thanks |
|
e*********i
发帖数: 33 | 48 PMID: 25482940
Cancer Biol Ther. 2014 Nov 2;15(11):1542-51. doi: 10.4161/15384047.2014.
956599.
Polymorphisms of p53 and MDM2 genes are associated with severe toxicities in
patients with non-small cell lung cancer.
Email:[email protected]
/* */
谢谢！ |
|
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x**4
发帖数: 112 | 50 http://www.ncbi.nlm.nih.gov/pubmed/25944127
Products for the treatment of inflammatory bowel disease: a patent review (
2013 - 2014)
Expert Opin Ther Pat. 2015 Jun;25(6):629-42. doi: 10.1517/13543776.2015.
1041921.
Thanks. |
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