h*******o
发帖数: 4884 | 1 1) due to the intrinsic difference between rodent Abeta and human Abeta,
rodent Abeta do not form aggregates easily as human abeta.
For more detailed info, check "Charles G. Glabe" or Frank Laferla's paper.
As for NFT, most people in the field now agree that Tau is downstream of
Abeta.
2) Calcium and neurocytotoxicity hypothesis is quite old. It definitely has
its points but not the whole scheme.
3) Abeta is solube. The problem is Abeta oligomer. And the current opinion
is that soluble Abeta ol... 阅读全帖 |
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p*****m
发帖数: 7030 | 2 要我说这个是urban legend，rodent比human还是差得远
而且 从我一个fly person的眼光看来，rodent model对生物学的贡献比线虫和果蝇的零
头都不如 |
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l**********1
发帖数: 5204 | 3 预先打了伏笔了哈 Wo Kao Nature News
Performance enhancement: Superhuman athletes
Enhancements such as doping are illegal in sport — but if all restrictions
were lifted, science could push human performance to new extremes.
Helen Thompson
18 July 2012
Code breaking
Gene doping — enhancing performance by adding or modifying genes — has
been the subject of locker-room gossip for the past ten years. There are
plenty of natural mutations for which to wish. The Finnish cross-country
skier Eero Mäntyrant... 阅读全帖 |
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l**********1
发帖数: 5204 | 4 BGI or others just try
NGS with both blood samples Ye Shiwen and Katie Ledecky
plus below six athletes total 8 athletes
performance profiling”方法，将所有国际上
有名的现役游泳运动员的比赛成绩，进行profiling分析，发现最高分排名（也就是最
“anomalous”的排名）是：
1. Elizabeth Beisel
2. Michael Phelps
3. Rebecca Adlington
4. Ian Thorpe
5. Stephanie Rice
6. Allison Schmitt
while can find proof of her EPOR mutation which is identical to Finnish
cross-country skier Eero Mäntyranta
and also is different to former matchs any DNA samples Ge... 阅读全帖 |
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N*******g
发帖数: 2 | 5 A one-year (with the possibility of one additional year) postdoctoral
fellow position will be available in the laboratory of Dr. Qi Wang in the
Department of Biomedical Engineering at Columbia University in April 2013 to
study neural coding in the somatosensory pathway.
The lab focuses on neural coding and brain-machine interfaces. The
successful candidate should have a Ph.D. degree in the area of Neuroscience,
Biomedical Engineering or a closely related discipline. Applicants with
demon... 阅读全帖 |
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M*****n
发帖数: 16729 | 6 A postdoctoral fellow position is available in the lab of pediatric
nephrology in the Department of Pediatrics and Communicable Diseases at the
University of Michigan, Ann Arbor, MI.
The postdoctoral fellow will be working on projects using in vitro cell
culture and rodent models to study renal glomerular function and related
diseases. The research projects involve the generation of transgenic cell
lines using the CRISPR Cas9 system; generation and maintenance of rodent
models of kidney diseases... 阅读全帖 |
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O**********5
发帖数: 3 | 7 Two positions for Postdoctoral Research Scientists
We are seeking highly qualified and motivated candidates who share a passion
for scientific discovery to join an interactive team.
Post #1: The molecular and cellular mechanisms controlling the balance of
immune response in the mouse brain.
Chronic neuroinflammation is a common feature of the ageing brain and a
variety of neurodegenerative disorders. However, the molecular and cellular
mechanisms underlying the regulation of innate immunity in t... 阅读全帖 |
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m********a
发帖数: 239 | 8 I am thinking about creating a virus that overexpresses a receptor
protein in rodents. Should I use rodent cDNA or human cDNA? Which one is
preferred? |
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m*********n
发帖数: 215 | 9 这么naive的问题。。。这个当然是看你要实验怎么设计啊。。。如果你觉得这个
receptor human和rodent的version 功能有区别的话。。。。两个都做。没区别就
rodent。。。 |
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N*******g
发帖数: 2 | 10 A one-year (with the possibility of one additional year) postdoctoral
fellow position will be available in the laboratory of Dr. Qi Wang in the
Department of Biomedical Engineering at Columbia University in April 2013 to
study neural coding in the somatosensory pathway.
The lab focuses on neural coding and brain-machine interfaces. The
successful candidate should have a Ph.D. degree in the area of Neuroscience,
Biomedical Engineering or a closely related discipline. Applicants with
demon... 阅读全帖 |
|
O**********5
发帖数: 3 | 11 Two positions for Postdoctoral Research Scientists
We are seeking highly qualified and motivated candidates who share a passion
for scientific discovery to join an interactive team.
Post #1: The molecular and cellular mechanisms controlling the balance of
immune response in the mouse brain.
Chronic neuroinflammation is a common feature of the ageing brain and a
variety of neurodegenerative disorders. However, the molecular and cellular
mechanisms underlying the regulation of innate immunity in t... 阅读全帖 |
|
h*h
发帖数: 18873 | 12 看来无所不在啊。
Coyote's deadly attack on cat spurs concern in Torrance neighborhood
Awakened at 4 a.m. Thursday by the family dogs barking, Steven Rime figured
it was one of the usual triggers -- a skunk or opossum or raccoon passing
through the neighborhood on the border of Torrance and Redondo Beach.
"Living in the (Hollywood) Riviera we end up with varmints of all kinds,"
Rimes said. "But my wife looks outside and on our front lawn we have a gray
coyote of about 80 to 100 pounds -- big ears -- eati... 阅读全帖 |
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B**y
发帖数: 824 | 13 有两种理论，一种是人工驯化，一种是自愿。自愿驯化更站得住脚，野猫喜欢到人类聚
居处抓老鼠，人类对猫比较容忍，时间长了，野猫就自动进化成家猫了。
其实狗的驯化也很相似，狼在人类聚居处找人剩下的食物吃，时间长了，就进化成狗了。
Cats have either a mutualistic or commensal relationship with humans. Two
main theories are given about how cats were domesticated. In one, people
deliberately tamed cats in a process of artificial selection, as they were
useful predators of vermin.[34] This has been criticized as implausible,
because the reward for such an effort may have been too little; cats
generally do not carry o... 阅读全帖 |
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D****u
发帖数: 3217 | 14 My house/backyard is totally rodents, reptiles, birds- Free.
My cats killed them all, even flies won't be able to escape. |
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D****u
发帖数: 3217 | 15 No, just kill for fun
they mark their territory with urine no rodents dare to approach. |
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l*****i
发帖数: 20533 | 17 Young trees or trees that are not completely winter-hardy should be
protected, particularly where winters are harsh or where temperatures
fluctuate widely during winter months. Winter trunk wraps are good ideas for
trees where small rodents and other animals depend on tree bark above the
snow line for winter food. There are, however, times when tree wraps can do
more harm .......
http://www.ehow.com/how_5527184_winter-wrap-tree-trunks.html |
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Y****g
发帖数: 662 | 18 警察因口头威胁被迫辞职
http://www.huffingtonpost.com/2012/11/22/cop-quits-assassinate-
Cop Quits After Saying He Would Volunteer To Assassinate Obama
11/22/12 07:21 AM ET EST
redditstumblefark
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Video, Obama Assassination, Cop Obama Assassination, Cop Quits Assassinate
Obama, Obama Assassination Cop, Obama Assassination Police Officer, Police
Officer Obama Assassination, Crime News
Navy Yeoman ... 阅读全帖 |
|
c****i
发帖数: 688 | 19 大民主国尽管降价在国际市场上推销粮食，仍然卖不出去，粮食堆在港口烂掉。
同时，印度2012年营养不良儿童占44%， 人民只吃两顿饭。饥饿指数23%，是全世界三
个饥饿指数正增长的国家。和索马里，刚果并列。
India's grain mountain grows despite push for exports
SINGAPORE/NEW DELHI (Reuters) - India will be unable to consume or export
enough wheat and rice to rein in a record stockpile after another bumper
harvest, a failure that means crops risk rotting in fields instead of being
sold on world markets to cash in on higher prices.
In March, farmers in India will begin to harvest the sixth consecutiv... 阅读全帖 |
|
l*******o
发帖数: 5673 | 20 国内的低智商文科记者又把“Alexei Surov博士”抄了一遍
在反转基因的战场上，经常被引用的一条新闻是俄罗斯科学家的“最新研究结果：转基
因食品有害”，http://www.tech-food.com/kndata/1026/0053268.htm。
这条新闻最早出自Voice of Russia去年4月份的一篇文章，Russia says genetically
modified foods are harmful，http://english.ruvr.ru/2010/04/16/6524765.html 主角是Institute of Ecology and Evolution Russian Academy of Sciences的Alexei Surov博士，他将仓鼠分组饲养，一组吃普通伙食，一组吃普通大豆，一组吃一些转基因大豆，再一组狂吃转基因大豆，然后再观察这些小动物的状况（别怪我没讲清楚，原话就是We did not add anything for one group but the other was fed with soya that contained ... 阅读全帖 |
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b**********a
发帖数: 930 | 21 法国2年喂转基因玉米的动物实验结果，转发越多越好
非常可怕的结果
现在国际通用90天喂养动物
2年喂养转基因玉米的结果
刊物名字 Food and Chemical Toxicology， 2012年9月19日online发表
http://zhiyanle.blog.hexun.com/88547457_d.html
Final review of the Séralini et al. (2012a) publication on a 2-year rodent
feeding study with glyphosate formulations and GM maize NK603 as published
online on 19 September 2012 in Food and Chemical Toxicology
欧盟现在出资300万欧元对这个研究进行更深入工作
国内有些专家对事实做了篡改：一是把欧盟官方文献中的“安全评估”和“风险评估”
的内容砍掉，从而篡改了原文的结论目标和内容;二是把欧盟机构的责任放到法国学者
头上、搞责任篡改;三是故意不提欧盟官方实际上是接受... 阅读全帖 |
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t******r
发帖数: 8600 | 22 这是绝对正确的态度。LZ可以说是无知者无畏吧。
看看LZ的美国爹什么的怎么说吧：
The International Agency for Research on Cancer Exit Disclaimer (IARC), a
component of the World Health Organization, has recently classified
radiofrequency fields as “possibly carcinogenic to humans,” based on
limited evidence from human studies, limited evidence from studies of
radiofrequency energy and cancer in rodents, and weak mechanistic evidence (
from studies of genotoxicity, effects on immune system function, gene and
protein expression, cell si... 阅读全帖 |
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t******r
发帖数: 8600 | 23 尼玛你小学毕业了吗？我的观点就是这事还没有定论。我给了5个机构的看法，三个说
“more research is needed”，你不识字啊？！
The International Agency for Research on Cancer Exit Disclaimer (IARC), a
component of the World Health Organization, has recently classified
radiofrequency fields as “possibly carcinogenic to humans,” based on
limited evidence from human studies, limited evidence from studies of
radiofrequency energy and cancer in rodents, and weak mechanistic evidence (
from studies of genotoxicity, effects on immune system function, gene... 阅读全帖 |
|
a*****y
发帖数: 33185 | 24 http://www.washingtontimes.com/news/2013/aug/6/chellaney-chinas
CHELLANEY: China’s salami-slicing strategy
Beijing works incessantly to redraw political boundaries
By Brahma Chellaney - - Tuesday, August 6, 2013
China’s furtive, incremental encroachments into neighboring countries’
borderlands have emerged as a key destabilizing element in Asia. While China
’s navy and a part of its air force focus on asserting revanchist
territorial and maritime claims in the South China and East China seas, it... 阅读全帖 |
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g***j
发帖数: 40861 | 25 trade name:Innate
品种： Ranger Russet
品质：reduce the formation of black spot bruises by lowering the levels of
certain enzymes in the potatoes. In addition, they are engineered to produce
less acrylamide by lowering the levels of an amino acid called asparagine
and by lowering the levels of reducing-sugars. Acrylamide is a chemical that
can form in some foods during high-temperature cooking, such as frying, and
has been found to be carcinogenic in rodents. |
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x****o
发帖数: 21566 | 26 Even though the two terms intuitively sound as if they should mean the same,
in fact, "Food security" suggests the adequacy of food to society, the
equitable distribution, confirmed supply, fair access, sustained sources,
etc. A "secure supply" of food. To a lesser degree, food security does
acknowledge the importance of food safety as well.
"Food safety" is concerned with safe sources of all foods, freedom from
avoidable chemical and microbial contamination, continuing the appropriate '
cold-... 阅读全帖 |
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f*******y
发帖数: 8358 | 28 https://thinkprogress.org/trump-education-secretary-public-schools-
3eb20d886c49#.xpmwxm2c9
How much could Trump’s education secretary damage public schools? Just look
at Detroit.
Detroit schools help explain Betsy DeVos’ mission.
President-elect Donald Trump and Betsy DeVos shake hands at Trump National
Golf Club Bedminster clubhouse in Bedminster, N.J., Saturday, Nov. 19, 2016.
CREDIT: AP/Carolyn Kaster
President-elect Donald Trump has tapped Betsy DeVos, a philanthropist and a
strong supporte... 阅读全帖 |
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s*********e
发帖数: 5245 | 29 傻逼。脏构不成EVICTION的合法理由.
https://www.landlordology.com/deal-with-hoarder-tenants/
How to Deal with Hoarder Tenants
Last updated on July 30, 2015 by Lucas Hall
33
14
shares
Dealing with Hoarder TenantsFor landlords and property managers, discovering
that you have a hoarder tenant living in one of your properties can be
distressing.
In this article, I will discuss the steps you can take to protect your
property without infringing on your tenant’s rights to reasonable
accommodations.
Hoarding is a Men... 阅读全帖 |
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s*********e
发帖数: 5245 | 30 Depending on their behavior, the hoarding may constitute a non-economic
breach of the lease, which *could* be grounds for eviction. Though landlord
can’t evict a tenant for hoarding, you can evict them for something else.
Check to see if your tenant is in breach of contract for any of the
following reasons:
Directly damaging to the property
Blocking emergency exits
Interfering with ventilation or sprinkler systems
Storing potentially explosive materials
Keeping perishable goods in a manner that ... 阅读全帖 |
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发帖数: 1 | 31 Keeping perishable goods in a manner that could attract mold or rodents
看帖了吗
landlord |
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发帖数: 1 | 32 Seven years after earning tenure at the College of Wooster, Judith C.
Amburgey-Peters is still working a "nonstop, crazy schedule on 6,000
different things." But she is not sure whether the 80 hours a week she
spends leading the chemistry department, advising students, and trying to
squeeze in time for research will ultimately qualify her for promotion to
full professor.
"When I asked a few years back who could help me with my five-year
professional plan, the looks I got back were: What planet a... 阅读全帖 |
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w****e
发帖数: 1883 | 33 老邱吹了好几年牛逼终于露馅了，又懒又笨还不能吃苦，被没受过教育的红脖子彻底比
下去了。人家那才是正儿八经的劳动人民。老邱也就是个rodent而已。 |
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发帖数: 1 | 34 老邱吹了好几年牛逼终于露馅了，又懒又笨还不能吃苦，被没受过教育的红脖子彻底比
下去了。人家那才是正儿八经的劳动人民。老邱也就是个rodent而已。 |
|
发帖数: 1 | 35 【 以下文字转载自 Animals 讨论区 】
发信人: CornucopiaX (VE RI TAS), 信区: Animals
标 题: Caracal 狞猫
发信站: BBS 未名空间站 (Thu May 10 20:27:51 2018, 美东)
狞猫（拉丁学名：Caracal caracal），体型中等，毛发有许多种颜色，栖息在干燥的
旷野，也有其在山区、树丛和沙漠活动的踪迹。
主食鸟类、小兽，以小家族形式在一起，有一定的领地意识，并用尿液标记领地的范围
，狞猫跳跃能力极强，奔跑速度快，能捕捉降落或起飞时的鸟类，主要分布在非洲，西
亚，南亚西北部等地。
The caracal (Caracal caracal) is a medium-sized wild cat native to Africa,
the Middle East, Central Asia, and India. The caracal is characterised by a
robust build, long legs, a short face, long tufted ... 阅读全帖 |
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发帖数: 1 | 36 【 以下文字转载自 Animals 讨论区 】
发信人: CornucopiaX (VE RI TAS), 信区: Animals
标 题: Serval 藪貓
发信站: BBS 未名空间站 (Thu May 10 20:31:20 2018, 美东)
The serval (Leptailurus serval) /ˈsɜːrvəl/ is a wild cat
native to Africa. It is rare in North Africa and the Sahel, but widespread
in sub-Saharan countries except rainforest regions. On the IUCN Red List it
is listed as Least Concern.[1]
It is the sole member of the genus Leptailurus and was first described by
German naturalist Johann Ch... 阅读全帖 |
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S*******l
发帖数: 4637 | 37 提醒过你了。既然你不去看自己引用的文章，我就替你把文章结论贴上来吧：
An extraordinarily large volume of animal data has been compiled to evaluate
the carcinogenic potential of glyphosate. The expected normal biological
variability for spontaneous tumor formation is reflected across this
extensive data set (Tables 20–23). However, no specific neoplasm stands out
as a consequence of glyphosate exposures. While some individual studies may
note an increase in a specific neoplasm at the high dose, the pooled data
fail to identify any... 阅读全帖 |
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m**********n
发帖数: 27535 | 38 The great waves of plague that twice devastated Europe and changed the
course of history had their origins in China, a team of medical geneticists
reported Sunday, as did a third plague outbreak that struck less harmfully
in the 19th century.
最后一段是重点：
The likely origin of the plague in China has nothing to do with its people
or crowded cities, Dr. Achtman said. The bacterium has no interest in people
, whom it slaughters by accident. Its natural hosts are various species of
rodent such as marmo... 阅读全帖 |
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d*****u
发帖数: 17243 | 39 Euarchontoglires (synonymous with Supraprimates) is a clade and a superorder
of mammals, the living members of which belong to one of the five following
groups: rodents, lagomorphs, treeshrews, colugos and primates. |
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发帖数: 1 | 40 The Muroidea are a large superfamily of rodents, including mice, rats, voles
, hamsters, gerbils, and many other relatives.
The muroids are classified in six families, 19 subfamilies, around 280
genera, and at least 1750 species.
要清查一遍，工作量很大。
现在急着下结论，不可能正确。 |
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s******n
发帖数: 518 | 41 【 以下文字转载自 History 讨论区 】
发信人: shaodian (有熊), 信区: History
标 题: 美国生物实验室泄露
发信站: BBS 未名空间站 (Sun Mar 22 15:25:05 2020, 美东)
Google翻译一次只能3900字符。
https://www.usatoday.com/story/news/2015/05/28/biolabs-pathogens-location-
incidents/26587505/
Investigation reveals hundreds of accidents, safety violations and near
misses put people at risk
Alison Young and Nick Penzenstadler, USA TODAY
Vials of bioterror bacteria have gone missing. Lab mice infected with deadly
viruses have escaped, and wild rodents have b... 阅读全帖 |
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D*V
发帖数: 3096 | 42 大民主国尽管降价在国际市场上推销粮食，仍然卖不出去，粮食堆在港口烂掉。
同时，印度2012年营养不良儿童占44%， 人民只吃两顿饭。饥饿指数23%，是全世界三
个饥饿指数正增长的国家。和索马里，刚果并列。
India's grain mountain grows despite push for exports
SINGAPORE/NEW DELHI (Reuters) - India will be unable to consume or export
enough wheat and rice to rein in a record stockpile after another bumper
harvest, a failure that means crops risk rotting in fields instead of being
sold on world markets to cash in on higher prices.
In March, farmers in India will begin to harvest the sixth consecutiv... 阅读全帖 |
|
|
O*****g
发帖数: 1257 | 44 No wonder things are so rotten these days. There is rodent infestation in
the White House. I blame Boosh and global warming. |
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r*s
发帖数: 2555 | 46 Trump, in a statement, said he had no idea whether or not the Enquirer story
is true or not, but denied having anything to do with it.
"I did not know about it, and have not, as yet, read it. I have nothing to
do with the National Enquirer and unlike Lyin’ Ted Cruz I do not surround
myself with political hacks and henchman and then pretend total innocence,"
Trump said. "Ted Cruz’s problem with the National Enquirer is his and his
alone, and while they were right about O.J. Simpson, John Edwards,... 阅读全帖 |
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B********s
发帖数: 2575 | 47 有没有人出来认真讲讲，我想破头皮也想不通什么样的人支持她（修正：仅限于自食其
力，自尊自爱的人）
请支持者说说看，她最大成就是什么，你们为什么支持她？
撇开她的那些丑闻不说，先一个字都不提她干过的坏事。她给人的印象就相当于国内那
种从中学大学开始就立志往上爬的党棍，一辈子追求权力。
如果在国内，我们屁民没有权利反对这种人。
可是，为什么来了美国，你还要支持这样一个权欲熏天的党棍呢？
她讲话，眼睛瞪得像牛一样，分明在说“你们这些傻逼，为什么还要麻烦我老人家亲自
出来拉票？我当总统，是你们屁民的福分，别不识抬举，赶快滚去给我投票” |
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c*******4
发帖数: 1874 | 48 提了700多提案吧，通过了三个，造一条马路，盖一个邮局和一栋砖房 |
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