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全部话题 - 话题: recurrence
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d*w
发帖数: 384
1
where was the pathology read? i don't trust pathology reports from China,
even the biggest hospitals, much. someone wanted me to have a look of his
case, and the path report said predominantly solid, but the only picture on
the report was predominantly micropapillary to me. i asked the blocks to be
sent to a pathologist i work with, and it was confirmed as predominantly
micropapillary. it was from one of the biggest hospitals.
your mom's case is a little difficult to give a consensus recommendat... 阅读全帖
D*******y
发帖数: 189
2
Thanks again for your helpful reply.
1. does she have access to low dose CTI will say no. if yes, then it makes
observation 
more comfortable.
I am going to say yes though I don't know what dose is regarded as low dose
for CT. She does have access to a hospital with lousy doctors but with 5
different CT machines, all brand new. The oncologist here the US recommended
ct every 6 to 8 weeks but everybody in China thinks it is excessive and
wanted to do it every 6 months.
2. her age, we already... 阅读全帖
g*******e
发帖数: 64
3
来自主题: NextGeneration版 - 向备受堵奶困扰的mm超级强烈推荐!!
感谢楼主分享这个方法,尤其是这个原理,反正我原来不知道。
另外,shuangseyun你堵奶都到了乳腺炎的地步了,卵磷脂肯定没用了,毕竟是营养品
,不是药。
Lecithin has been recommended to combat recurrent plugged ducts. The usual
recommended dosage for recurrent plugged ducts is 3600-4800 mg lecithin per
day, or 1 capsule (1200 milligram) 3-4 times per day. After a week or two
with no blockage, mom can reduce the dosage by one capsule. If there is no
blockage within another 2 weeks she can reduce it again by one. Mom may need
to continue taking 1-2 capsules per day if s... 阅读全帖
w******y
发帖数: 4871
4
来自主题: NextGeneration版 - 悲催求祝福,不到一天背靠背两次ER
this is what those "smart" people usually do.
Let me give you an example why I do not think patient should seek medical
advice here.
A patient's post on online forum: I have allergies, nose congestion, always
got sinus infection, headache, but no wheezing now, and currently i am on
Dulera and albuterol. what should I do.
reply from A: you dont have wheezing, try to not to use Dulera
reply from B: you need to see your doctor
reply from C: try some vitamin D.
reply from D,E,F: blah, blah, blah,
I ... 阅读全帖
w******y
发帖数: 4871
5
Chapter 11: the infant and toddler with wheezing.
AuthorsRobison RG, et al. Show all Journal
Allergy Asthma Proc. 2012 May-Jun;33 Suppl 1:S36-8. doi: 10.2500/aap.2012.33
.3543.
Affiliation
Division of Allergy-Immunology, Department of Medicine, Northwestern
University Feinberg School of Medicine, Chicago, Illinois, USA.
Abstract
Recurrent wheezing is common in young infants and toddlers with 27% of all
children having at least one wheezing episode by the age of 9 years. The
initial wheezing epis... 阅读全帖
w******y
发帖数: 4871
6
治疗上一般都会用到inhaled albuterol , inhaled steroid。
Respiratory syncytial virus and asthma: speed-dating or long-term
relationship?
Authors
Piedimonte G.
Journal
Curr Opin Pediatr. 2013 Jun;25(3):344-9. doi: 10.1097/MOP.0b013e328360bd2e.
Affiliation
The Cleveland Clinic Pediatric Institute and Children's Hospital, Cleveland,
Ohio, USA.
Abstract
PURPOSE OF REVIEW: Respiratory syncytial virus (RSV) is the most common
respiratory pathogen in infants and young children worldwide. Furthermore,
epidemiologi... 阅读全帖
a*****g
发帖数: 19398
7
Common Core losing support of Tennessee teachers, survey finds
By Joey Garrison [[email protected]
(function(){try{var s,a,i,j,r,c,l,b=document.getElementsByTagName("script");l=b[b.length-1].previousSibling;a=l.getAttribute('data-cfemail');if(a){s='';r=parseInt(a.substr(0,2),16);for(j=2;a.length-j;j+=2){c=parseInt(a.substr(j,2),16)^r;s+=String.fromCharCode(c);}s=document.createTextNode(s);l.parentNode.replaceChild(s,l);}}catch(e){}})();
/* ]]> */
]
Support for Common Core among Tennessee teach... 阅读全帖
C*****5
发帖数: 8812
8
来自主题: Stock版 - [BSSD] GTX1080是业余GPU
image处理主要以convolutional network为基础,speech和股价都可以看作time
series数据,所以recurrent network比较流行。
Deep learning在金融界的应用我了解不多,不过很多用recurrent network,尤其是
LSTM做股票预测的,一搜有好多论文呢,github有很多source code可以参考。
高频的散户没搞头,要拼硬件,中长期的可以搞搞作参考,估计效果比看KDJ/MACD也好
不了多少。
Deep Learning和传统machine learning比的优势,我个人认为,是比较不要求domain
knowledge。传统machine learning都要hand crafted features,要数学功底好才行,
deep learning 只要有大量数据,建好model扔给机器算就好了(当然构建和调试model
也是很需要功力的)。我懂得也有限,暂时没想过用这个赚钱。有空了可以写个model
玩一玩。
P********6
发帖数: 709
9
Dynavax Announces Acceptance of Two Data Abstracts for SD-101 in Combination
with KEYTRUDA® for Presentation at the 2018 Ameri
2018-03-15 10:30:02.354 GMT
Dynavax Announces Acceptance of Two Data Abstracts for SD-101 in Combination
with KEYTRUDA® for Presentation at the 2018 American Association for
Cancer Research (AACR) Annual Meeting
Data from Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
(HNSCC)
Durability Data in... 阅读全帖
g*2
发帖数: 658
10
这个要慎入。有问题,查个关键词,看看。
SPECIFIC INJURIES
Hip injuries
Overview and approach — Hip injuries are less common in runners than
injuries to the lower extremity and they can be difficult to diagnose.
Nevertheless, during jogging, the hip joint is subjected to loads up to
eight times body weight and both acute and chronic injuries can occur [55].
In runners, the differential diagnosis of hip pain includes gluteus medius
tendinopathy, piriformis syndrome, stress fracture of the femoral neck,
labral tear, a... 阅读全帖
k****a
发帖数: 4944
11
主要是保Medical方面的,
谢谢你的意见!
Trip Protection
A B
Trip Interruption Trip Interruption
$5,000 max. $5,000 max.
Baggage Loss Baggage Loss
$250 max. (secondary) $250 (secondary)
Medical
Medical Limit Medical Limit
$50,000 (+$0) (s... 阅读全帖
n**e
发帖数: 2026
12
来自主题: WaterWorld版 - 抑郁症有妄想表现吗?
张纯如精神障碍的正式诊断是抑郁症。根据美国精神病诊断权威标准DSM-5(附件1),
抑郁症是没有妄想表现的。也就是说,如果一个人被诊断为抑郁症,就不应该有妄想表
现。如果一个人有妄想表现,就不应该诊断为抑郁症。
那么确诊为抑郁症的病人是否可以出现妄想呢?回答是肯定的。但是,当一个抑郁症病
人出现妄想症状,原来的“抑郁症”就不再适用于病人。这种情况下就要改变诊断为“
精神病性抑郁症”。这种病人往往同时会出现幻觉症状。相应的治疗和保护措施也要作
出改变。相关学术依据见附件2。
有些人说张纯如有精神病。所谓的日本右翼极端势力对她不断发出暴力威胁其实是她的
妄想。起码从医生给她的正式诊断来看,张纯如没有妄想症状。
附件1 :Criteria for Major Depressive Episode: DSM-5
A. Five (or more) of the following symptoms have been present during the
same 2-week period and represent a change from previous functioning; a... 阅读全帖
n**e
发帖数: 2026
13
来自主题: WaterWorld版 - 澄清关于抑郁症的几个术语问题
抑郁症(Major Depressive Disorder)与精神病性抑郁 (Psychotic depression)与燥郁
症(Bipolar disorder)均为独立的疾病实体,相互之间没有概念从属关系。张纯如的
诊断最初是抑郁症(Major Depressive Disorder),后来有医生诊断燥郁症(Bipolar
disorder)。这两个疾病都没有妄想表现。
1. 抑郁症是独立的疾病实体。 Clinical depression goes by many names --
depression, "the blues," biological depression, major depression.
http://psychcentral.com/disorders/depression/
关于抑郁症的诊断标准。附录1 :DSM-4 Criteria for Major Depressive Disorder (
MDD) ,与附录2:DSM-5 Criteria for Major Depressive Episode, 在具体内容上没
有不同。都没有妄想表现。... 阅读全帖
d****o
发帖数: 32610
14
As of 2015 FMT for recurrent C. difficile infections can be done without
mandatory donor and stool screening if performed by a patient at home,
whereas FMT performed by a physician for recurrent C. difficile infections (
or other indications) cannot be performed without an IND.[51]
P******o
发帖数: 3428
15
拉肚子比较复杂。。
http://blog.trupanionpetinsurance.com/tag/pre-existing/#axzz1Go
Pre-existing conditions are commonly excluded in pet health insurance plans,
and are described as any illness which first occurs prior to the pet’s
policy inception date. An injury or recurrence of an injury can also be
considered a pre-existing condition.
http://www.buzzle.com/articles/pet-insurance-for-pre-existing-c
Pet Insurance for Curable Pre Existing Conditions
Dog and cat insurance for pre existing conditions is al... 阅读全帖
N******t
发帖数: 16051
16
来自主题: pets版 - 关于男猫的尿道堵塞
assuming这些死因和尿堵是independently occur的话,不应该改变活下来的猫里面尿
堵的概率阿
根据wikipedia上面cite的这篇文章:"Evaluation of the effect of a long-term
trap-neuter-return and adoption program on a free-roaming cat population",
野猫的平均年龄是4.7岁
根据我刚大致扫了一眼的一篇比较recent的review:“Recent Concepts in Feline
Lower Urinary Tract Disease”,lower urinary tract disease高发年龄为2-6岁
所以感觉长寿以及更多的medical care不能完全解释发病率
我的没有数据不负责任的point是,家猫发病率很大程度上是人为因素造成的,不见得
是猫自然选择进化的结果
至于具体是哪些人为因素,摘抄一下那篇review里面的几段话在下面
总结一下就是:
尿道疾病高发年龄是2-6岁;1岁以下和10岁以上罕见
其中非堵型的尿道疾病在男猫... 阅读全帖
c****t
发帖数: 19049
17
来自主题: SciFiction版 - 云图 英文版
LETTERS FROM ZEDELGHEM
CHATEAU ZEDELGHEM,
NEERBEKE,
WEST VLAANDEREN
29TH-VI-1993
Sixsmith,
Dreamt I stood in a china shop so crowded from floor to far-off ceiling with
shelves of
porcelain antiquities etc. that moving a muscle would cause several to fall
and smash to bits.
Exactly what happened, but instead of a crashing noise, an august chord rang
out, half-cello,
half-celeste, D major (?), held for four beats. My wrist knocked a Ming vase
affair off its
pedestal—E-flat, whole string section, g... 阅读全帖
b********g
发帖数: 2156
18
来自主题: TrustInJesus版 - 我觉得神的设计是最完美的
看到后面的那个链接,终于明白你在说什么了。
我还以为你很专业呢,你怎么也不研究一下就人云亦云呀。
vagus nerve 到 aortic arch 那里分叉,分出一条recurrent laryngeal nerve,正好
在主气管的下端,由下往上,控制颈部肌肉。有什么问题吗?
你贴的那个文章一开头就错了,什么绕过心脏,明明是在主动脉那里分出的支神经,你
最好量量看有多长,再决定是不是绕了弯路,可别把vagas nerve也一块儿量进去了。
我估计你贴的文章里就把vagas nerve也当recurrent laryngeal nerve算了。
另外,这文章说是美国教授的文章翻译过去的,我找了半天没找到原文,你能找到吗?
我想看一下。
b**x
发帖数: 3451
19
那个,我统计也不行的。我知道一个两个变量的例子,我说说,你觉得有没有灵感吧。
是做某种病毒的recurrence的。想看看感染时的年纪和性别是不是对recurrence frequ
ency有关系。这个好像就是两个变量的。如果考虑你的control和A+B这两个组,就确实
是两个变量。所以,用two-way也确实有道理。
你用one-way和two-way有什么区别么?如果two-way的结果不好,你可以考虑跟学校里统
计学的老师啥的联系,咨询一下。如果结果没什么区别,觉得可以考虑用two-way。
T**********e
发帖数: 29576
20
下面这篇文章对Jobs的胰腺内分泌癌治疗总结的不错,看来死的有点冤。
1. 10-2003 确诊,07-2004终于手术切除,期间Jobs一直在试自己选的diet疗法。扫描发现癌变在扩大才动了手术,这段时间癌转移的多少不可知,但肯定越拖转移的越多。
2.手术后没化疗和放疗。Jobs 2005年演讲说这表明病情乐观,不知是哪个庸医给他灌输的。2004年手术是大面积切除,部分胰腺和胃和小肠,胆和胆管都切除,目的是要消除扩散,但不系统化疗和放疗怎么能最大程度减少扩散威胁?哪个外科大夫这么信自己的手艺?
3.2009年换肝,这在扩散性癌治疗是有争议的,因为换肝后压制免疫反应有可能促进别处癌的生长。也有可能当时肝已经不行了没办法。
这种癌正常治疗大多数可活10年以上,Jobs真该到东岸Hopkins或Harvard找个靠谱的大夫。
Jobs’s Unorthodox Treatment
Some of Apple trailblazer Steve Jobs’s cancer treatment choices, from
alternative therapies to a liver tra... 阅读全帖
w**z
发帖数: 8232
21
https://aws.amazon.com/message/5467D2/?utm_content=buffere5a1e&utm_medium=
social&utm_source=linkedin.com&utm_campaign=bufferSummary of the Amazon
DynamoDB Service Disruption and Related Impacts in the US-East Region
Early Sunday morning, September 20, we had a DynamoDB service event in the
US-East Region that impacted DynamoDB customers in US-East, as well as some
other services in the region. The following are some additional details on
the root cause, subsequent impact to other AWS services t... 阅读全帖
c*****e
发帖数: 3226
22
来自主题: Programming版 - Re: [BSSD] GTX1080是业余GPU (转载)
【 以下文字转载自 Stock 讨论区 】
发信人: CRH1235 (江左没狼), 信区: Stock
标 题: Re: [BSSD] GTX1080是业余GPU
发信站: BBS 未名空间站 (Thu Sep 1 16:40:33 2016, 美东)
image处理主要以convolutional network为基础,speech和股价都可以看作time
series数据,所以recurrent network比较流行。
Deep learning在金融界的应用我了解不多,不过很多用recurrent network,尤其是
LSTM做股票预测的,一搜有好多论文呢,github有很多source code可以参考。
高频的散户没搞头,要拼硬件,中长期的可以搞搞作参考,估计效果比看KDJ/MACD也好
不了多少。
Deep Learning和传统machine learning比的优势,我个人认为,是比较不要求domain
knowledge。传统machine learning都要hand crafted features,要数学功底好才行,
deep learning 只要... 阅读全帖
c*****e
发帖数: 3226
23
来自主题: Programming版 - Re: [BSSD] GTX1080是业余GPU (转载)
这个讲的很好:
A convolutional network is basically a standard neural network that's been
extended across space using shared weights. A recurrent neural network is
basically a standard neural network that's been extended across time by
having edges which feed into the next time step instead of into the next
layer in the same time step. There's a kind of similarity between the two
but it's pretty abstract (easier to see if you unroll the recurrent neural
network)
Intuitively, we can see that CNNs are id... 阅读全帖
l**********1
发帖数: 5204
24
Oui
please refer Network-based genome-wide association studies (NWAS)
for identifying prognostic gene signatures to predict cancer recurrence.
report on
//www.cse.buffalo.edu/ACM-BCB2010/
by
Ying-Wooi Wan, Swetha Bose, James Denvir, and Nancy Lan Guo
Title:
A Novel Network Model for Molecular Prognosis
Abstracts:
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes
and functional pathways in biomarker identification. This study presents a novel ne... 阅读全帖
l**********1
发帖数: 5204
25
Oui
please refer Network-based genome-wide association studies (NWAS)
for identifying prognostic gene signatures to predict cancer recurrence.
report on
//www.cse.buffalo.edu/ACM-BCB2010/
by
Ying-Wooi Wan, Swetha Bose, James Denvir, and Nancy Lan Guo
Title:
A Novel Network Model for Molecular Prognosis
Abstracts:
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes
and functional pathways in biomarker identification. This study presents a novel ne... 阅读全帖
D******9
发帖数: 2665
26
突变五花八样, 大多数蛋白在细胞里, 又没有酶活性。 健康人早点测个序, 假如有
这些突
变,早点做个肠镜才是真的。
Comprehensive molecular characterization of human colon and rectal cancer.
Cancer Genome Atlas Network.
Abstract
To characterize somatic alterations in colorectal carcinoma, we conducted a
genome-scale analysis of 276 samples, analysing exome sequence, DNA copy
number, promoter methylation and messenger RNA and microRNA expression. A
subset of these samples (97) underwent low-depth-of-coverage whole-genome
sequencing. In total, 16% of co... 阅读全帖
u*********1
发帖数: 2518
27
如果你不是做技术开发,就直接的PCR+sanger sequencing
尤其因为你的样本不多,而且只做一个基因(当然一个基因或许有multiple的exon)
如果你要做比如3000个sample,同时做40个基因,那这个方法肯定就不行了,
最先进的办法请看:
Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism
Spectrum Disorders
http://www.sciencemag.org/content/338/6114/1619.abstract
当然未来whole exome测序的成本变得非常非常低的时候,这方法估计也要淘汰
btw,上面的science paper测了几千个样本的44个基因,最后也就发现6个recurrent
de novo mutated gene,也只能解释1%的sporadic ASD,所以我觉得disease genetics
还是任重道远
H*g
发帖数: 2333
28
来自主题: Biology版 - proposal abstract
I took a glance at what you have here. I could only contribute my thoughts
regarding of the proposal, but not about oncology.
1. The logic flow of the first 4 sentences in the Abstract is terrible. How
about saying something like (maybe wrong in science and need to be better
rephrased) "Colon cancer is the second most common cause of death from
cancer in the United States. One of factors that contribute to this high
severity is due to its high rate of recurrence. As the source of cancer
recurren... 阅读全帖
u**6
发帖数: 8
29
来自主题: MedicalCareer版 - need help, question of CK form 2
Thanks again,
But one more question about #3,
If she is acute pyelonephritis only not recurrent, you are right tx:
blood culture and iv antibiotics .
But this case:Her history” she has vesicoureteral reflux and a history of
recurrent urinary tract infections”, do we need to take a CT scan and
Ultrasound first?
S******9
发帖数: 2837
30
来自主题: MedicalCareer版 - CK NBME 4 Block1 Q1
1. 15y girl had recurrent candidal infections of the skin and nucous
membranes since childhood, 2 years Hx of type 1 DM and 1y Hx of autoimmune
thyroiditis.
Which of the following is the most likelymechanism of her recurrent candidal
infections?
A. Autoimmune destruction of the thymus
B. Blunting of the inflammatory response from complement deficiency
C. deficiency in anticandidal Ab
D. Impaired cell-mediated immunity
E. inability of macrophage to present candidal antigen
I thought this girl has... 阅读全帖
f****i
发帖数: 129
31
来自主题: MedicalCareer版 - CK NBME form 2 question
34.
A 57-year-old woman is brought to the emergency
department because of
abdominal pain for 12 hours. Over the past 3 hours,
the pain has become
severe and generalized. Over the past month, she has
had mild upper
abdominal discomfort that is relieved by eating. She
has a history of
recurrent migraines treated with sumatriptan as
needed. Her temperature
is 38.2 C (100.8 F), blood pressure is 170/95 mm Hg,
and pulse is
110/min. Abdominal examination shows mild distention;
there is marked
rigidity... 阅读全帖
l*******d
发帖数: 449
32
The greatest concern with SLNB is the potential of a false negative result,
which could increase the potential for axillary recurrence. However, despite
the approximately 5 to 10 percent false negative rate with SLNB found in
studies in which completion ALND has been done, several series suggest that
axillary recurrence rates are low after a negative SLNB alone in early stage
breast cancer (range 0 to 4.5 percent) [17-27].
http://www.uptodate.com/contents/sentinel-lymph-node-biopsy-for
y******7
发帖数: 17
33
来自主题: Nursing版 - 请教Med/Surg常用药物名字!
The following is what I collected when I was a student doing capstone in a
local hospital. Not sure if it is useful.
Lidocaine topical is a amide-type local anesthetic. for production of
topical anesthesia, relief of pain associated with postherpetic neuralgia,
reduction of gagging during dental procedures, prevention and control of
urethral pain, anesthetic lubricant for endotracheal intubation, and relief
of hemorrhoidal pain.
Polyethylene glycol(Miralax) is a nonabsorbed solution used to trea... 阅读全帖
l******i
发帖数: 1404
34
你说的很对,这是一类问题。
但是没法用一元linear recurrence的解法(通过给特征多项式求根得到recurrence form)
Hint:
Functions defined on n-grids can also be studied with PDE.
Given: f(m,n)=f(m-2,n)+f(m-1,n)+f(m-1,n-1)+f(m,n-2)+f(m,n-1);
=> f(m+2,n+2)=f(m,n+1)+f(m+1,n+2)+f(m+1,n+1)+f(m+2,n)+f(m+2,n+1);
f_x(m,n) = f(m+1,n)-f(m,n)
f_y(m,n) = f(m,n+1)-f(m,n)
f_xy(m,n) = f(m+1,n+1)-f(m,n+1)-f(m+1,n)+f(m,n)
f_xx(m,n) = f(m+2,n)-2*f(m+1,n)+f(m,n)
f_xxy(m,n) = f(m+2,n+1)-2*f(m+1,n+1)+f(m,n+1)-f(m+2,n)+2*f(m+1,n)-f(m,n)
f_yy(m,n) = f(m,n+2)-2... 阅读全帖
i******t
发帖数: 370
35
来自主题: Quant版 - 问个面世题
Actually there is no magic about martingale.
If you are interested, here is the other solution mentioned in the previous
post. Essentially we want to solve recurrence relation:
p(k)=1/2*p(k+2)+1/2*p(k-1), with p(a)=1, p(-b)=0
The characteristic equation of this recurrence relation is x=1/2 * x^3 + 1/2
. Roots are x1=1, x2=(sqrt(5)-1)/2, x3=(-sqrt(5)-1)/2. General solution is p
(n)=w1*x1^n+w2*x2^n+w3*x3^n+w0. You will need to solve w_i, and make p(n) in
[0, 1].
Comparing this to the martingale ap... 阅读全帖
I***e
发帖数: 1136
36
来自主题: Science版 - 淋雨的概率
I forgot what it was called. But the content says:
If a Markov chain is recurrent and irreducible and have finite
states, then the limiting measure will be the stationary measure
no matter what initial measure you choose. ( Recurrent means with
probability one the Markov chain will revisit its starting point.
Irreducible means you can reach any state from any other state
if you wait long enough. )
It is contained in the Markov chain chapter of Richard Durrett's
book.
Thanks, all.
Icare
R*****n
发帖数: 8658
37
来自主题: Science版 - Re: Help in Markov Chain
好象没怎么说清楚:
有穷MC,既不可能只有非常返(transient),也不可能有NULL RECURRENT.
SO,if the chain is irreducible and finite, then all the states can only be
positive recurrent.
c**d
发帖数: 104
38
来自主题: Statistics版 - 工作上的问题, 急需大虾指点!
Wang, M.C., Chang, S.H. 1999. Nonparametric Estimation of
a Recurrent Survival Function. Journal of the American
Statistical Association 94:146{153.
or search "Nonparametric Estimation with Recurrent Event Data"

past
Y******Y
发帖数: 8753
39
来自主题: Statistics版 - repeated event survival data
包子please!
recurrent event model,比较多人用的有几个
1) Anderson-Gill的counting process model,假设recurrent event之间是独立的
2) PWP(Prentice-William-Peterson) model: 这个分两种,一个是gap time model,
一个是total time model
3) WLW (Wei-Lin-Weissfield) model,这个是marginal model
SAS的proc phreg就可以fit这三个model,只要你把data准备成符合sas的counting
process格式。
具体code看这里
http://www.ats.ucla.edu/stat/sas/faq/survival_repeated_events.h
a*i
发帖数: 1652
40
来自主题: MedicalDevice版 - Corrective and Preventive Action (CAPA)
http://en.wikipedia.org/wiki/Corrective_and_preventive_action
Corrective and preventive action (CAPA, also called corrective action /
preventive action) is a concept within good manufacturing practice (GMP).
CAPA focuses on the systematic investigation of discrepancies (failures and/
or deviations) in an attempt to prevent their recurrence (for corrective
action) or to prevent occurrence (for preventive action). To ensure that
corrective and preventive actions are effective, the systematic
inves... 阅读全帖
yf
发帖数: 272
41
来自主题: Medicalpractice版 - 求助-乳腺癌术后治疗方案和营养
Your mother has stage IIIA(T3N0M0) ER positive/PR positive/HER2 positive
Invasive ductal carcinoma. There is discrepancy regarding the PR status and
Ki 67 percentage. Ki 67 is usually not so reliable. PR status is considered
positive in the second hospital pathology but negative in the first hospital
pathology. Anyway the cancer is high risk, your mother needs chemotherapy,
radiation therapy, 1 year of trastuzumab(Herceptin), and at least 5 years of
aromatase inhibitor. Every part of the treatme... 阅读全帖
c***z
发帖数: 6348
42
来自主题: DataSciences版 - [Data Science Project] Location data quality
终于完成了project。
Summary of Findings. Overall we were able to verify the hypothesis regarding
partner quality and location recurrence; we were also able to design a fast
mechanism to classify partners by data quality based on location recurrence
; finally we were able to identify and correct for errors in hand labeling.
The engineers will take over implementation, even though I would like to do
it myself on Scala + Spark...
m***r
发帖数: 359
43
来自主题: DataSciences版 - 机器学习日报2015年2月楼
机器学习日报 2015-02-12
@好东西传送门 出品, 过刊见
http://ml.memect.com
订阅:给 [email protected]
/* */ 发封空信, 标题: 订阅机器学习日报
更好看的HTML版
http://ml.memect.com/archive/2015-02-12/short.html
1) 【特征工程系列文章】 by @爱可可-爱生活
关键词:经验总结, 算法, Python, 博客, 集成学习, 特征工程
[文章]《Selecting good features》特征工程系列文章:Part1.单变量选取 [1]
Part2.线性模型和正则化 [2] Part3.随机森林 [3] Part4.稳定性选择法、递归特征排
除法(RFE)及综合比较 [4] 内容很赞,还有Python代码示例,强烈推荐!
[1] http://blog.datadive.net/selecting-good-features-part-i-univariate-selection/
[2] http://blog.datadive.net/selectin... 阅读全帖
m***r
发帖数: 359
44
来自主题: DataSciences版 - 大数据日报 2015年2月楼
机器学习日报 2015-02-19
@好东西传送门 出品, 过刊见
http://ml.memect.com
订阅:给 [email protected]
/* */ 发封空信, 标题: 订阅机器学习日报
更好看的HTML版
http://ml.memect.com/archive/2015-02-19/short.html
1) 【百度Deep Speech讨论会视频】 by @黄浩XJU
关键词:深度学习, Andrew Ng, 行业动态
昨天百度Deep Speech讨论会视频 Andrew Ng ‏ @AndrewYNg Starting right
now! Presentation on Deep Speech breakthrough on deep learning+speech.
Livestream [1]
[1] https://freeflowapp.com/v/2ajfgt
2) 【SearchOnMath:数学搜索引擎】 by @网路冷眼
【SearchOnMath:数学搜索引擎】 [1] SearchOnMath 旨在让学生和研究者... 阅读全帖
t*******o
发帖数: 1464
45
来自主题: _pennystock版 - EXEL 和 BMY 分道扬镳了
怎么解读?我怎么感觉是 BMY把EXEL抛弃了,是吧?
关键句: Given the recent progress of BMS' wholly-owned oncology pipeline and
positive data generated by XL184, Exelixis and BMS were not able to align
on the scope
http://www.streetinsider.com/Press+Releases/Exelixis+Regains+Full+Rights+to+Develop+and+Commercialize+XL184/5744353.html
Exelixis Regains Full Rights to Develop and Commercialize XL184
1:15a ET June 21, 2010 (Business Wire)
Exelixis, Inc. (Nasdaq:EXEL) today announced that it has regained full
rights to develo... 阅读全帖
D**R
发帖数: 371
46
来自主题: _pennystock版 - CVM
How about this one?
CVM
VIENNA, Va.--(BUSINESS WIRE)-- The following letter is being released by CEL
-SCI Corporation (NYSE AMEX: CVM) to its shareholders:
Dear Fellow Shareholders:
At the end of last year we were excited to report that we started our
pivotal Phase III trial for Multikine® in advanced primary head and neck
cancer. This study is designed to demonstrate that our novel approach to
the treatment of cancer is efficacious. If it is, as we believe the study
will show, we will be ab... 阅读全帖
D**R
发帖数: 371
47
来自主题: _pennystock版 - CVM
How about this one?
CVM
VIENNA, Va.--(BUSINESS WIRE)-- The following letter is being released by CEL
-SCI Corporation (NYSE AMEX: CVM) to its shareholders:
Dear Fellow Shareholders:
At the end of last year we were excited to report that we started our
pivotal Phase III trial for Multikine® in advanced primary head and neck
cancer. This study is designed to demonstrate that our novel approach to
the treatment of cancer is efficacious. If it is, as we believe the study
will show, we will be ab... 阅读全帖
m****g
发帖数: 530
48
FRANKLIN LAKES, N.J., July 30 /PRNewswire-FirstCall/ -- A new analysis finds
that women in New Jersey who
take the breast cancer drug tamoxifen in conjunction with certain popular
antidepressants may be at a higher
risk for a breast cancer recurrence. Women taking tamoxifen along with
certain SSRIs have a 2-fold increased
risk of breast cancer recurrence compared to women not taking these drugs
together.
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