i*******n 发帖数: 48 | 1 这种情况应该是Necrosis
你最好加Caspase inhibitor block apoptosis,再看PI+有没有变化。
很多时候的death是mixed form.
microarray不能说明什么问题,因为所谓的apoptosis相关的基因不是那么绝对的。
另外一个就是看细胞形态,necrosis能看到细胞破裂。
Good Luck.
necrosis)
necrotic |
|
n*****k 发帖数: 69 | 2 想研究一个蛋白对细胞necrosis 的作用。首先得建立一个细胞necrosis的模型,请问
有哪些常用的方法?
多谢多谢! |
|
n*****k 发帖数: 69 | 3 想研究一个蛋白对细胞necrosis 的作用。首先得建立一个细胞necrosis的模型,请问
有哪些常用的方法?
多谢多谢! |
|
A******d 发帖数: 571 | 4 我的一个细胞系,用药物处理之后annexinV/PI染色作facs,annexinV+/PI+(necrosis)
的增多,但是annexinV+/PI-(apoptosis)的没有变化,可是我的microarray结果显示很
多和apoptosis相关的基因上调了。如果说药物作用时间太长导致apoptotic的necrotic
,那我处理4小时也是同样的结果。
请问,会不会apoptosis 在某些细胞里就会引起细胞膜破裂? |
|
z*****i 发帖数: 28 | 5 降低药物浓度试试。
necrosis)
necrotic |
|
s******a 发帖数: 472 | 6 凋亡晚期不也是双阳性吗?同意LS建议降低浓度
necrosis)
necrotic |
|
s****l 发帖数: 395 | 7 做个activated caspase + PI的flow比较准
necrosis)
necrotic |
|
j******1 发帖数: 1315 | 8 我们用细胞筛选药物,看到细胞G0/G1 arrest,细胞死亡,想做点机理。cell
necrosis最常用的方法有哪些?请大牛指点。 |
|
j******1 发帖数: 1315 | 9 各位大牛除了apoptosis,necrosis和autophagy细胞还有别的死法吗? |
|
b******a 发帖数: 704 | 10 来自主题: Medicalpractice版 - 两个病例 谢谢楼上的老师们。 看见ultrasound就傻眼了。
If it's cystic mass, fine needle aspiration cytology (FNAC) is required
according to my review book.
DDX: fat necrosis of the breast;
breast infection, abscess, mastitis;
Fibrocystic lesion;
Fibroadenomas;
Breast cancer
I also found a review about fat necrosis of the breast :
http://www.ncbi.nlm.nih.gov/pubmed/16198567
Breast. 2006 Jun;15(3):313-8
The aetiological factors includes trauma (21–70%), radiotherapy,
anticoagulation (war farin),cyst aspiration, biopsy,... 阅读全帖 |
|
e****0 发帖数: 678 | 11 • Exaggerated deep tendon reflexes can be seen in lock in syndrome.
• Non bleeding varices are managed with nonselective beta-
adrenergic antagonists, such as propranolol.
• Sclerotherapy, endoscopic band ligation, and surgery are
indicated after a patient has a first episode of variceal bleeding.
• TIPS is a last resort in variceal bleeding unresponsive to
medical and endoscopic intervention.
• Ischemic colitis
CT—thickening of eth bowel ... 阅读全帖 |
|
s****l 发帖数: 395 | 12 cell death以前是三分法,apoptosis,autophagic cell death, necrosis。现在倾向
于两分法,apoptosis vs necrosis。necorsis以前认为不能被调控,不过后来发现在
特定的treatment条件下induce的necroptosis是RIP kinase dependent的。
necroptosis与necrosis的phenotype一样,不过我认为只能算是necrosis中的一种。最
近有个iron-dependent的Ferroptosis发在Cell上,不过我觉得不是特别striking |
|
w***r 发帖数: 709 | 13 我不是NIBS黑。我以前的帖子里说过NIBS的水平在美国完全是top10的。前面的帖子里
已经解释了我所谓“一般”的含义。也是相对于晓东以前工作的水平和影响。
我不是做Necrosis的,只是觉得它的生理作用和已知的凋亡的意义无法相比。也许只在
某些特殊的细胞和条件下,才会有所谓“可调控的”的坏死。另外线粒体的动态变化和
凋亡的关系已经提出过了,我也不认同“又”开辟了Necrosis的一扇大门(如果你指的
是这个方面)。文章做得很漂亮,尤其是这一篇 Mixed Lineage Kinase Domain-like
Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase。
言语有些夸张和不当的地方见谅,以上为个人观点。
欢迎指教 |
|
s*********s 发帖数: 110 | 14 sina上有个comment
NIBS-王晓东实验室发现Necrosis的分子机制 此博文包含图片 (2014-04-12 14:
41:15)[编辑][删除]转载▼
NIBS-王晓东实验室发现Necrosis的分子机制
NIBS-王晓东实验室发现Necrosis的分子机制
在April 10发表的Molecular Cell杂志封面文章中,王晓东实验室描述了MLKL的磷酸化
是如何导致了细胞程序化坏死的分子机制。MLKL的磷酸化使其从单体状态向多聚体状态
的转化。多聚化的MLKL可以结合多种磷脂,从而由细胞质(弥散分布)转移到细胞膜和
细胞器膜上;并在这些膜结构中形成通透性孔道,从而破坏膜的完整性,引起细胞坏死
。这一点有点类似于细胞凋亡中的重要的蛋白Bax和Bak, 在细胞凋亡领域,Bax/Bak在
细胞凋亡过程在线粒体表面聚集,多聚之后形成孔道,从而释放细胞色素C(Cyto C),
诱导细胞凋亡小体,从而激活Caspase3,最后导致细胞凋亡。
这篇文章同时介绍了王晓东实验室还开发了(Epitomics公司)能特异识别人源p-MLKL磷
酸化的单克隆抗体,并证明这一磷酸... 阅读全帖 |
|
s****l 发帖数: 395 | 15 necroptosis只是necrosis的一种(HeLa cell没有RIP3同样可以necrosis),其他的
necrosis好像研究的不多 |
|
S******9 发帖数: 2837 | 16 我最近参考朋友给的uw笔记,自己做了一些,下面是样本,看看如何?
Alcoholic liver disease:
- Alcoholic steatosis (Fatty liver)
- Alcoholic hepatitis( mallory bodies, neut, infiltration, perivent, inflamm
, liver cell necrosis)
- Alcoholic cirrhosis/fibrosis
F atty liver, alcohol hepatitis , and even early fibrosis can all be
potentially reversible if alcohol intake is stopped except late stages of
fibrosis and cirrhosis.
True cirrhosis (with regeneratrve nodules) is irreversible, regardless of
alcohol abstinence
Alcoholic fatty... 阅读全帖 |
|
M*****e 发帖数: 279 | 17 "肌肉中大量产生的肌酸激酶来不及排出,释放到血液中,引起肾小管堵塞,导致急性
肾功能损伤".
应当不是“肌酸激酶”。而是骨骼肌(属横纹肌)损伤后,大量的“肌球蛋白”(
myoglobin)释放到血液中,引起肾小管堵塞,导致急性肾功能损伤。
Reference:
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001505/
A.D.A.M. Medical Encyclopedia.
Rhabdomyolysis
Last reviewed: September 19, 2011.
Rhabdomyolysis is the breakdown of muscle fibers that leads to the release
of muscle fiber contents (myoglobin) into the bloodstream. Myoglobin is
harmful to the kidney and often causes kidney damage.
Causes, incidence, and risk factor... 阅读全帖 |
|
L******k 发帖数: 2945 | 18 看到了这个:
Commando:
(One of the best Commando abilities is Armour Breaker. It basically ignores
physical resistance on enemies)
Gandayaks - Yaschas Massif (010AF+01XAF) - Good Early Peaker, good Strength
boosting passives incl. Armour Breaker. Basically, use as Infusion fodder
for your later monsters.
Chichu - Archylte Steppe - Throw Mog into patch of red flowers near the
Cactuar Waystone on the plains of eternity. When fully leveled has a very
high strength, fast attack animation, Armour Breaker a... 阅读全帖 |
|
h*****o 发帖数: 342 | 19 你说的这些检测都是imaging,在鱼上面好做么?游来游去的,有人专门做鱼的imaging
?你有没有paper推荐?我对imaging这方面挺有兴趣的
中风后神经元的Ca2+会上升,引发glutamate大量释放,进一步打开钙通道,引起细胞
死亡或凋亡。。你这样筛出来的分子类型大概都取决于你image什么分子吧。如果你用
luciferase联接necrosis的基因,你筛出来的药都是和阻断necrosis相关的。你决得这
样能发现新的机理吗? |
|
p*****m 发帖数: 7030 | 20 挺好做的 实际上我说的这几个思路都是被证明可以在活鱼上用的 因为其实你不需要关
心具体的荧光来源 只要采集总信号就行了。比如说有人在circadian gene (per, cyc)
promoter连个luciferase,就能在自由游泳的鱼里看到表达量的周期变化;等等。我站
内msg你一些别的paper吧
后面这个当然存在direct/indirect relation的问题 这些指标
之所以提出来主要是因为容易上量 而不是因为它们能本质性的反映问题,等screen之后
更精细的研究还是需要的。就拿你这个necrosis做例子 筛出来的molecule得看看是通过
溶栓 是通过降低血管内壁细胞脱落,是通过保护neuron还是什么来降低necrosis的
imaging |
|
p*****m 发帖数: 7030 | 21 恩 看behavior也不错 如果看behavior不高通量的话就看necrosis marker的表达也是
不错感觉(怎么感觉也没有什么很好的necrosis specific gene marker? hehe)。 |
|
e****0 发帖数: 678 | 22 • leukemia
ALL AML CLL
child adult elderly
BM lymphoblasts 25%myeloblasts
lab Lymphocyte 5000, mature-appearing cells
• Osgood-schlatters disease
Adolescent male athletes
Traction apophysitis—quadriceps tendon put the traction on the
apophysis of the tibial tubercle where patellar tendon inserts.
A firm mass =heterotopic bone formation
Pain can be reproduced by extending the kne... 阅读全帖 |
|
R*******t 发帖数: 367 | 23 来自主题: Medicalpractice版 - 两个病例 Conclusion of this case:
There is no doubt post-op fluid has component of fat necrosis. The fluid I
drained looks like those from liposuction. In training, we always take cases
with a final diagnosis of A or B. But in real life, A and B can happen
simultaneously, since patients come in without reading a textbook first.
This case is seroma/fat necrosis with superimposed infection. Patient was
put on vanco and has been doing well.
I remember A++ once showed a case with MS and spinal stenosis. The ... 阅读全帖 |
|
b******l 发帖数: 1632 | 24 细胞自己死啊,一种是 apoptosis,另一种是 necrosis,这两种的机理,从大面上来
说,还是研究得比较透了的,虽然现在依然很热门。 |
|
f****r 发帖数: 5118 | 25 这是啥?科普一下?是不是加了点apoptosis/necrosis,细胞就活了? |
|
b******l 发帖数: 1632 | 26 那还是要么 apoptosis,要么 necrosis,看你的处理有多 hash 了。
那倒未必,新陈代谢重要性在于,生命机制是活体代谢,
是一个开放的体系,需要控制进出平衡,你可以控制进,不能控制出,如果你把进
给断了,生命体光出不进,失去代谢平衡,载体就消失,生命就没了。
维持细胞活性,需要培养基,就是为了代谢循环有来源。 |
|
L*****G 发帖数: 12375 | 27 美帝比其他帝国好一点,以身作则,美国人自己也剃毛。
美帝的结局有且只有2个:1。apoptosis.如果Ron Paul 上台的话 2. necrosis. |
|
P********R 发帖数: 1691 | 28 Abstract
The health effects of a Roundup-tolerant genetically modified maize (from 11
% in the diet), cultivated with or without Roundup, and Roundup alone (from
0.1 ppb in water), were studied 2 years in rats. In females, all treated
groups died 2–3 times more than controls, and more rapidly. This difference
was visible in 3 male groups fed GMOs. All results were hormone and sex
dependent, and the pathological profiles were comparable. Females developed
large mammary tumors almost always more o... 阅读全帖 |
|
K**********n 发帖数: 1197 | 29
跟这帮自称理科的文科生物wsn实在纠缠不清楚。给丫们上点洋大人自己的说法吧,而
且都是学术圈的,已有reference一堆,其中一份是著名的兰德公司的报告。
另外,美国和澳洲已立法限制使用脑波扫描仪,拿脑波扫描仪扫本国公民已是联邦法的
重罪。不过这个比较难的是你无法证实谁接收了你的脑信号。所以立了法跟没立一个样。
Remote Mind Control Technology
Reprinted from SECRET AND SUPPRESSED: BANNED IDEAS AND HIDDEN
HISTORY, edited by Jim Keith, $12.95, available from
1-800-680-INET.
There had been an ongoing controversy over health effects of electromagnetic
fields (EMF) for years (e.g., extremely low frequency radiation and the
Navy's Project Sea... 阅读全帖 |
|
y***u 发帖数: 7039 | 30 Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically
modified maize
Food and Chemical Toxicology
Volume 50, Issue 11, November 2012, Pages 4221–4231
Abstract
The health effects of a Roundup-tolerant genetically modified maize (from 11
% in the diet), cultivated with or without Roundup, and Roundup alone (from
0.1 ppb in water), were studied 2 years in rats. In females, all treated
groups died 2–3 times more than controls, and more rapidly. This difference
was vis- ible in... 阅读全帖 |
|
g***j 发帖数: 40861 | 31 【 以下文字转载自 PKU 讨论区 】
发信人: mumu221 (), 信区: PKU
标 题: 复旦大学杭州校友会会长、博士生导师曹明富大量文章抄袭和造假
发信站: BBS 未名空间站 (Wed Sep 14 05:15:38 2016, 美东)
复旦大学杭州校友会会长、博士生导师曹明富大量文章抄袭和造假
http://bbs.tianya.cn/post-free-5558181-1.shtml
复旦大学杭州校友会会长、博士生导师曹明富大量文章抄袭和造假,曹明富作为世界名
校复旦大学的校友,居然出现这么多低劣的抄袭文章,真为复旦大学蒙羞!详情如下:
可以查到曹明富一共34篇文章,其中3篇和生物无关,9篇综述,非第一或者通讯作
者9篇,会议论文1篇,2篇文献搜索不到,剩下10篇论著,居然8篇存在一稿多投或者相
互抄袭:
1. 文章1抄袭1999年《中国兽医学报》11月文章《茶多酚(GTPP)的抗脂质过氧化
作用》
2. 文章2和9为同一文章,一稿两投。
3. 文章6和文章10抄袭1993年《茶叶科学》的文章《茶多酚的生学学作用》
4.文章31,33,34内容相互重复,多处投稿。其... 阅读全帖 |
|
l*****7 发帖数: 8463 | 32 Cancer researcher retracts 19 studies at once
with 23 comments
jcheng
Jin Cheng
A former cancer biologist at the Moffitt Cancer Center in Tampa, Florida has
retracted 19 papers from a single journal.
Jin Cheng, who studies how ovarian cancer develops, withdrew 19 papers from
the Journal of Biological Chemistry originally published over the last 15
years, and corrected another. All of the retractions are for image
manipulation.
For example, here’s the notice for “Activation of phosphatidylinosito... 阅读全帖 |
|
Q*****Y 发帖数: 741 | 33 复旦大学博士,复旦大学杭州校友会会长曹明富大量文章抄袭和造假
http://bbs.tianya.cn/post-free-5558181-1.shtml
复旦大学博士,复旦大学杭州校友会会长曹明富大量文章抄袭和造假,详情如下:
可以查到曹明富一共34篇文章,其中3篇和生物无关,9篇综述,非第一或者通讯作
者9篇,会议论文1篇,2篇文献搜索不到,剩下10篇论著,居然8篇存在一稿多投或者相
互抄袭:
1. 文章1抄袭1999年《中国兽医学报》11月文章《茶多酚(GTPP)的抗脂质过氧化
作用》
2. 文章2和9为同一文章,一稿两投。
3. 文章6和文章10抄袭1993年《茶叶科学》的文章《茶多酚的生学学作用》
4.文章31,33,34内容相互重复,多处投稿。其中,文章34的图8,图9,居然和文
章31的图2A,2B完全一致。
文章目录:
1、茶多酚类复合物对小鼠体内脂质过氧化的影响,《科技通报》,2000,V0L.16
N0.1
抄袭1999年《中国兽医学报》11月文章《茶多酚(GTPP)的抗脂质过氧化作用》
2、Effect ofTumor Necrosis Factor Alpha ... 阅读全帖 |
|
发帖数: 1 | 34 写这么多 你先去把apopsis和necrosis区别弄明白再说??
apopsis 细胞膜不破裂 后被吞噬细胞吞噬 胞内溶酶体不会溢出 病毒也不会溢出 没有
炎症
懂吗???
你写的这些常识就别逼逼了 google一下到处都是
CD8+ CTL怎么杀病毒感染的细胞你都不懂 还什么细胞裂解病毒跑出来感染其他细胞
真是啥也不懂 |
|
发帖数: 1 | 35 英文媒体也报道了
https://apnews.com/Business%20Wire/fe24e251ddb843a9b091561a06f8eead
Clover Initiates Development of Recombinant Subunit-Trimer Vaccine for Wuhan
Coronavirus (2019-nCoV)
CHENGDU, China--(BUSINESS WIRE)--Jan 28, 2020--
Clover Biopharmaceuticals, a global clinical-stage biotechnology company
focused on developing novel and transformative biologic therapies, today
announced that it has initiated development of a recombinant subunit vaccine
for 2019-nCoV, the newly identified coronavirus tha... 阅读全帖 |
|
k*******3 发帖数: 918 | 36 Li Hongzhi is confident his "body protection" Avatar, "my body is about what
he is able to do. You don't practice him regardless of you, you practice a
help in the end "(" Zhuan Falun "and" you go to Hongkong, you go to the
United States, you went to the moon, the sun will never mind, my lawbody can
protect. But not too much, my body is in your practice to your "" Zhuan
method "and so on, in a word, the body of what can be, what place can tube,
but only the disciples. When in July 4, 1998, Falun... 阅读全帖 |
|
发帖数: 1 | 37 In August 2, 2015, Macao Falun Gong leader Lin Yiming, although the Li Zhufo
shot "hair" treatment, eventually died of colon cancer died of illness; in
March 2, 2014, Falun Gong Li Dayong key due to acute necrosis of liver
disease death; in April 2013, was regarded as the obvious effects of
practicing Falun Gong "scientist" Liu Jinghang died of illness in the UK in
November 30, 2012, South Korea; the Falun Dafa Association vice president
Jin Zhenghao in a car accident in Gyeonggi Do, South Korea... 阅读全帖 |
|
m*******6 发帖数: 11762 | 38 When in July 4, 1998, Falun Gong Hainan counseling deputy director general
Chen Yong 8 Falun Gong backbone, travelling from Haikou to Sanya to spread
Falun Gong in the way of the car accident, Chen Yong and other 7 people were
killed and injured Zhang yijun. December 2007 South Korea "Falun Dafa
Association" the backbone of all strong because of traffic accident
sentenced was seriously injured, the rescue invalid death. In March 2, 2014,
Falun Gong an important backbone of Li Dayong because of a... 阅读全帖 |
|
A********e 发帖数: 354 | 39 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时,深深的鄙视一下自己的无聊行径!!
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
S***J 发帖数: 1210 | 40 云老师发了个贴说清华目前的找人标准,很多人不相信。特地调研了一下清华生命学院
最近回去的人的情况,如云老师所说,绝大多数都有2cns,如果只有一篇cns,那基本
上还有>2的子刊。这个不仅仅局限于胖老师经常说的结构生物学,而是所有方向都基本
如此。
当然这些新回去的绝大部分都是千青(有些不是的是因为回去那一年千青还没开始)。
网页上的Title有的是教授,有的是研究员,估计当时还没有统一。但校内一律都是副
教授,也就是相当于这边的AP。我还特地打听了一下,国内的TT制度好像没有Tenured
Associate这一档,清华5年考核通过了就是正经的full professor。
有些老师看不上国内的科研,我就仅列出两位回国后的publication,咱就不说颜宁等
这种Early T的个例了。说两个没太有名气的,还没有评上T的,各位老师可以参考一下
,看看自己有没有别人这么productive。
一. Guangshuo Ou (11年回国,千青)
Select item 25342559
1.CYLD mediates ciliogenesis in multiple organs b... 阅读全帖 |
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x*******a 发帖数: 11067 | 41 http://www.ncbi.nlm.nih.gov/pubmed/22999595
看关于GMO的讨论的时候看到的。本来就讨厌ROUND-UP,这下次更不敢用了。
Abstract
Background
The health effects of a Roundup-tolerant NK603 genetically modified (GM)
maize (from 11% in the diet), cultivated with or without Roundup application
and Roundup alone (from 0.1 ppb of the full pesticide containing glyphosate
and adjuvants) in drinking water, were evaluated for 2 years in rats. This
study constitutes a follow-up investigation of a 90-day feeding study
conducted by Monsanto in ... 阅读全帖 |
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f******I 发帖数: 769 | 42
steroid is for symptomatic relief, the other 4 are so-called disease
modifying antirheumatic drugs,
especially the latter 3 are the newer anti-tumor necrosis factor alpha drugs
that's really been used for varieties of autoimmune disease from rheumatoid
arthritis to inflammatory bowel diseases, they tend to be extremely
expensive and can reactivate certain diseases such as tb, |
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l**x 发帖数: 296 | 43 avascular necrosis of femeral head
一般都是手术治疗,换人工关节。 |
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h**l 发帖数: 7 | 44 非常感谢Myshoestring的回贴。医生在做手术的时候确实用一种溶液检查过盆腔内的
淋巴结,呈阴性,从而认为没有癌细胞扩散至盆腔内的淋巴结。现在已看到病理检查报
告:
This uterine smooth muscle tumor shows diffuse moderate to severe cytologic
atypia. There is a hemorrhage and focal necrosis. In addition, the mitotic
rate is as high as 10/10hpf. Based these parameters, it is classified as an
intermediate grade leiomyosarcoma.
下面是我的大致翻译:
这一子宫平滑肌瘤显示从中度到快速扩散非典型细胞。此外,有出血和病灶坏死。细胞
有丝分裂速率高达10/10hpf. 基于这些参数,这一子宫肌瘤划分为中度平滑肌肉瘤(癌)。
刚见过肿瘤医生,他首先安排CAT扫描,检查肺和别的器官是否被侵入,并建议伤口好
后,做第二次手术,切除子宫颈,卵 |
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b******8 发帖数: 24 | 45 hard to give much suggestion due to the limited information. think about
the 1) ischemic neuropathy causing by the artery stenois in the leg or the
pelvic 2) avascular necrosis in the hip 3) other polyneuropathy.
Demerol usually does not help much in the severe neuropathic pain. for
more suggestions, you may give me more information via this wed email. |
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f******I 发帖数: 769 | 46
ever thought about osteonecrosis, or aseptic necrosis? |
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g*****j 发帖数: 1211 | 47 Total hip replacement is the standard treatment. I have never heard of stem
cell treatment in this situation. As a matter of fact, I have never heard
of any stem cell treatment that has been accepted as a treatment in
situation other than "experiment".
Arthritis of the hip, requiring hip replacement is very common condition. I
doubt her steroid use is the culprit. Long term steroid use can lead to
femur head necrosis, but we are talking about really long term use. |
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l*h 发帖数: 4124 | 48 most cases nonsurgical (enema et.). surgery used for:
suspected necrosis, multiple recurrence, failure to be reduced nonsurgically
etc. |
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l*h 发帖数: 4124 | 49 股骨头坏死: most are avascular necrosis. for this type, the main treatment
is joint replacement. bone transplant is possible in some patients.
股骨头 English: femoral head, femur head, head of femur. Latin: caput
femoris. |
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R****y 发帖数: 411 | 50 What you described doesn't sound like avascular necrosis, ligamentous or
labrum pathology is more likely. X-ray won't help you, MRI is the way to go,
plus if you really have avn, it can be seen earlier on MRI that X-ray.
Certainly hope you don't have it though. Good luck |
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