s****l
发帖数: 10462 | 1 IPO Market Unlocking for 'Omics-related Companies, but It's 'Anything but
Robust'
December 30, 2010
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+EmailPrinter-friendly versionRSS FeedBy Tony Fong
NEW YORK (GenomeWeb News) – For most of 2010, the IPO market froze out the
life science tools and 'omics market, but by the end of the summer, there
were signs that the public markets may be slowly welcoming firms operating
in the space, as a handful of public offerings ended a cold snap.
The IPO market for 'omics firms has been a gri... 阅读全帖 |
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m***T
发帖数: 11058 | 2 想看具体的individual文章们，请follow最下面的link.
NEW YORK (GenomeWeb News) – In a very busy year for news in the 'omics and
molecular diagnostics industries, an article about an acquisition topped the
list of the most-read stories for the year on GenomeWeb Daily News, while
restructurings, lawsuits, and one firm's IPO plans made it into the top 10.
Here are the top 10 for the year:
1) Life Technologies CEO Defends Price for Ion Torrent, Dismisses Illumina's
PCR System
2) Roche Restructuring Plan Includes 4,8... 阅读全帖 |
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s******9
发帖数: 283 | 3 存活下来不容易啊。。。
http://www.genomeweb.com/genomeweb-feature-researchers-weigh-gr
NEW YORK (GenomeWeb News) – When Nicholas Navin's R01 grant to use single-
cell sequencing to study tumor evolution in breast cancer was first funded
in 2012, it was funded at 83 percent of the requested budget.
Because of the sequester, Navin's grant now will be cut a further 6 percent.
In addition, he has only been given funding for the next three months.
"After those three months, I assume that it will continue to be ... 阅读全帖 |
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m***T
发帖数: 11058 | 4 http://www.genomeweb.com//node/1217241?hq_e=el&hq_m=1567445&hq_
NEW YORK (GenomeWeb News) – Thermo Fisher Scientific is acquiring Life
Technologies in a $13.6 billion deal, the firms jointly announced today.
Thermo Fisher was rumored over the past couple of weeks to be in advanced
talks to acquire Life Tech, while private equity firms also had been
reported as working on bids to get a deal done. The transaction signing
comes three months after Life Tech confirmed it had hired Deutsche Bank and
M... 阅读全帖 |
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t*d
发帖数: 1290 | 7 Bill Talman, president of the Federation of Experimental Societies for
Experimental Biology, told GenomeWeb Daily News today that while the
president talked about "the restrictions all of us will have to face as a
result of the budget," certain things, particularly scientific research, are
"paramount in their importance for the country."
"I found it very appealing that the three that he listed had funding for
biomedical research at the front," he said.
"I think this president is committed in bot... 阅读全帖 |
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D******9
发帖数: 2665 | 8 SABiosciences was founded by a Chinese woman.
Qiagen Acquires SABiosciences for $90M
November 10, 2009
By a GenomeWeb staff reporter
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NEW YORK (GenomeWeb News) – Qiagen said yesterday that it has signed a
definite agreement to acquire SABiosciences, a privately-held developer and
manufacturer of disease- and pathway-focused PCR assay panels, for $90
million.
SABiosciences, based in Frederick, Md., employs some 100 workers. Its
primary product ... 阅读全帖 |
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T**N
发帖数: 129 | 9 这是真的么
October 11, 2013
Faulty Antibodies Continue to Enter US and European Markets, Warns Top
Clinical Chemistry Researcher
By Adam Bonislawski
One year after alerting the proteomics community to a Chinese life sciences
company that he said had infiltrated the US and European markets with faulty
antibodies, researcher Nader Rifai told ProteoMonitor this week that the
rogue firm is still at it.
Rifai, director of clinical chemistry at Children's Hospital Boston, first
warned of the faulty antibod... 阅读全帖 |
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m***T
发帖数: 11058 | 10 sequencing市场更热闹了。
http://www.genomeweb.com//node/1396761?utm_source=SilverpopMail
Roche Acquires Nanopore Sequencing Firm Genia Technologies for up to $350M
NEW YORK (GenomeWeb) – Roche said today that it will acquire Genia
Technologies for $125 million in cash and up to $225 million in additional
payments tied to milestones. Once the deal closes, Genia will be integrated
into the Roche Sequencing Unit.
Genia, based in Mountain View, Calif., has been developing a single-molecule
sequencing-by-sy... 阅读全帖 |
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m***T
发帖数: 11058 | 11 USPTO Declares Interference Proceeding to Adjudicate CRISPR Patent Spat
Jan 12, 2016 | a GenomeWeb staff reporter
NEW YORK (GenomeWeb) – The US Patent and Trademark Office yesterday
declared an interference proceeding to settle certain claims related to the
CRISPR patent battle between parties led by the Broad Institute and the
University of California, respectively.
In the interference proceedings, the USPTO will collect, consider, and
compare historical documentary evidence to establish invent... 阅读全帖 |
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b********w
发帖数: 334 | 12 直接面向个人
Tech Details:
- FDA approved Saliva collection kit.
- Agilent SureSelect V5 50MB chip
- 75x on target coverage (after mapping, filtering, and duplicate removal,
130-140x raw throughput)
- 99% Coverage > 1x
- 90% Coverage > 20x
- CLIA certified Illumina sequencing.
Deliverable
- Ownership of your genome
- VCF file (Beta 期间你要原始数据 BAM，我们也可以提供。)
- CLINVAR, CGD summary about your variants
- Traits
- Beta 期间你要原始数据，我们也可以提供。
Public exposure
Genomeweb:
https://www.genomeweb.com/molecular-diagnost... 阅读全帖 |
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发帖数: 1 | 13 Authors retract controversial NgAgo gene-editing study
Nature · 10 hours ago
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Retracted: Controversial study claiming alternative gene editor NgAgo
superior toCRISPR
geneticliteracyproject.org · 20 hours ago
“The data have spoken:” Controversial NgAgo gene editing ...
NgAgo Paper Retracted | GenomeWeb
https://www.genomeweb.com/scan/ngago-paper-retracted16 hours ago
Final Nail Hammered into NgAgo Coffin | The Scientist ...
www.the-scientist.com › The Scientist › The Nutshell16 hours ... 阅读全帖 |
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c****y
发帖数: 101 | 14 http://www.genomeweb.com/print/1446176
世界首例经MALBAC基因组扩增高通量测序进行单基因遗传病筛查的试管婴儿2014年9月
19日在北京大学第三医院出生，标志我国胚胎植入前遗传诊断技术已处于世界领先水平。
本例夫妻，男方为单基因显性遗传病患者，经历了多次手术治疗，非常痛苦。该疾病主
要是因为基因序列上发生了单个碱基的缺失，后代中无论男孩女孩都有二分之一概率患
同样的疾病。夫妻在北医三院生殖中心就诊，期望通过胚胎基因诊断帮他们挑选正常胚
胎，避免让自己的孩子患上同样疾病。
他们通过辅助生殖技术共获得18枚囊胚，医务人员利用显微操作技术获得极少量的细胞
，采用本研究组研发的单细胞基因组MALBAC扩增技术，将这些极少量胚胎细胞中的DNA
均匀扩增上百万倍以满足基因分析的需求，结合PCR技术与高通量测序技术，经过低深
度的测序（平均0.1X），可同时观察到全部染色体数目及结构是否异常，并能实现准确
的、单位点的关键基因检测。研究者从18枚胚胎中挑选出3枚既不包含致病位点又不包
含新发现的突变位点，同时染色体正常的胚胎，选择其中一枚移植到女方子宫内，胚... 阅读全帖 |
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发帖数: 1 | 15 CDC Will Implement Novel Coronavirus Surveillance in ...
NEW YORK – The US Centers for Disease Control and Prevention will begin
implementing surveillance for the novel coronavirus 2019-nCoV, also known as
SARS-CoV-2, at select public health labs. The testing will be piggybacked
onto a pre-existing national influenza surveillance system. Get the full
story with 360Dx Premium
https://www.genomeweb.com/pcr/cdc-will-implement-novel-coronavirus-
surveillance-select-public-health-labs?utm_source=Sail... 阅读全帖 |
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u*****a
发帖数: 6276 | 17 有个犹他州的生物公司，一直在搞有关自闭症的基因测试。也不知道是否有效。下面是
新闻：
Developmental disorders affect about 15 percent of children, and Lineagen
already offers a customized chromosomal microarray test, called FirstStepDx
Plus, as a first-line diagnostic test for their clinical evaluation.
According to the firm, the test has a clinical detection rate of about 30
percent. Microarray-based testing is recommended by the American College of
Medical Genetics and Genomics.
The new test, called NextStepDx Plus, promises to increas... 阅读全帖 |
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s****l
发帖数: 10462 | 18 USA IPO-ed:
PACB, raised $200M
GNOM, raised $54M
GNMK
Filed for IPO:
Atossa Genetics and Fluidigm
Tried to IPO
BG Medicines
IPO gets into the life science and diagnostic space, which I believe is the
hottest area in coming years. The companies with the best shots at being
taken public in the coming years are those in the next-generation sequencing
space, experts said. Next-gen sequencing "is the area of tools where I see
the greatest impact over the last year," Ericson said, "and specifically,
y... 阅读全帖 |
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x*****4
发帖数: 204 | 21 一篇文章被GenomeWeb daily news提到“What’s Worth Reading on the Web”能提吗？
这个能有什么contribution发掘吗？ |
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s****l
发帖数: 10462 | 26 ~~~~~Does this mean 21-century is Bio-century? Obviously no.~~~~~
Report: More Life-Science Jobs Despite Recession; Fewer Patents in Top-10
States
May 05, 2010
Type size: - + Email Printer-friendly version RSS Feed By Alex Philippidis
NEW YORK (GenomeWeb News) — Job creation by US life sciences employers
survived the first year of the recession in 2008, and thrived over most of
the previous two years, according to a new state-of-the-industry study
released last week.
The Battelle/BIO State Biosc |
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m***T
发帖数: 11058 | 28 订阅象biospace和genomeweb等一些网站的mail list，一般每天我都会收到若干这些网
站的一些重要新闻，包括pharma、biotech及clincial方面的新闻都有。如果手机有
data plan，并且能收email的话,能非常及时看到这些。我有一个gmail帐号专门是为订
阅这种news而准备的。 |
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a*****g
发帖数: 543 | 29 It is interesting you mentioned the genetically similarity within cell line
s. Most of these studies would have been done using millions (if not billio
ns )of cells. The bias of sequencing or SNP would lead to identify the most
obvious low hanging fruit, such as KRAS, pten, p53 etc.
Apparently when single-cell level sequencing becomes widely available, iden
tifying subpopulations with genetic or epigenetic characteristics will be i
n a much better position.
http://www.genomeweb.com/sequencing/si... 阅读全帖 |
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t*d
发帖数: 1290 | 32 http://www.genomeweb.com//node/980559?hq_e=el&hq_m=1103092&hq_l
----------------------------------------
A recent study by scientists at Yale University suggests that the actual
cost of sequencing may be much higher than some current estimates indicate
since those figures may not factor in the analysis costs that are necessary
for a successful sequencing project.
In the paper, published in Genome Biology last month, Yale's Mark Gerstein
and colleagues consider costs that weren’t taken into accou... 阅读全帖 |
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t*d
发帖数: 1290 | 33 MONTREAL (GenomeWeb News) – Analyses of data for nearly 1,100 individuals
assessed through phase 1 of the 1000 Genomes Project have uncovered more
than 40 million genetic variants in the human genome, including almost 30
million SNPs not detected previously.
Overall, the researchers identified some 37.9 million SNPs in the dataset,
including 29.7 million new SNPs. In addition, the team tracked down 3.8
million short indels and 14,000 large deletions. McVean noted that this set
represents highly ... 阅读全帖 |
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j****x
发帖数: 1704 | 35 NEW YORK (GenomeWeb News) – Helicos BioSciences filed for Chapter 11 bankru
ptcy protection on Thursday.
The Cambridge, Mass.-based single-molecule sequencing firm filed its petitio
n in US Bankruptcy Court for the District of Massachusetts after years of st
ruggling financially and trying to keep pace in the fast-moving next-generat
ion sequencing space. Under Chapter 11 bankruptcy, Helicos will be afforded
the opportunity to reorganize its operations, and the company said that it c
ontinues to... 阅读全帖 |
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s******9
发帖数: 283 | 36 Single-molecule技术，怎么才能robust...
Helicos Seeks Approval to Sell Assets, IP to Employee to Form New Company
March 11, 2013
NEW YORK (GenomeWeb News) – Helicos BioSciences, currently in Chapter 11
bankruptcy protection, is seeking approval from bankruptcy court to sell its
assets to an employee who plans to form a new company using Helicos'
technology, the company said in a court filing last week.
The US Bankruptcy Court for the District of Massachusetts Eastern Division
will hold a hearing on Heli... 阅读全帖 |
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n*********4
发帖数: 99 | 37 NEW YORK (GenomeWeb News) – The federal budget for fiscal year 2014 that
the Obama Administration released yesterday includes a request for $31.3
billion to fund the National Institutes of Health, which would be an
increase of 1.5 percent over the budget it received in FY 2012, the last
year the government passed a complete budget. In the current fiscal year,
the government is funded under a continuing resolution that provided $30.8
billion for NIH.
The funding proposal in the White House plan d... 阅读全帖 |
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s******9
发帖数: 283 | 39 http://www.genomeweb.com/sequencing/industry-experts-question-c
The group questioning the paper has issues with components of the physics,
enzymology, and chemistry behind the study.
One issue, said Lindsay, is that the study describes using superconducting
materials at the interface of the protein transistor and probes to reduce
signal decay. However, he said, "none of us know of a superconducting
material that works at the same temperature as a polymerase."
Superconducting materials operate at... 阅读全帖 |
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d*********e
发帖数: 52 | 43 NEW YORK (GenomeWeb) – The Stanley Center at the Broad Institute has
received a promise of $650 million from philanthropist Ted Stanley to fund
genomic research of psychiatric disorders in order to eventually identify
and develop molecularly targeted drugs. |
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M*P
发帖数: 6456 | 44 https://www.genomeweb.com/scan/double-blind-review
Currently, the journal follows a single-blind system in which the reviewers
are anonymous, but they know the identities of the authors whose manuscript
they are reviewing. In this new option, the reviewers would remain anonymous
and they would not know whose paper they are reviewing.
Such an approach, proponents say, would eliminate biases based on gender,
institutional affiliation, researcher reputation, and more.
However, Nature notes that oth... 阅读全帖 |
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n******7
发帖数: 12463 | 48 这是今天的一个新闻，Steve Horvath的研究我比较熟悉，之前还做过类似的领域。
这才叫原创的，临床相关的研究。不是随便扯个DL的名号就是。
顺便说个花边新闻，Steve之前读到一篇烂文，忘记是不是那个俄罗斯公司的了，也是
关于aging这块的生物信息分析。他想这块我专业啊，这种烂文是misleading，我得去
评论一下。于是就发了个comment，说这里面这里有问题，那里有问题。结果没多久，
居然收到一封那个公司寄来的律师信，威胁他必须撤销这个comment，哈哈哈
－－－
Life Insurer GWG Acquires Rights to Epigenetic Mortality Predictor Tech
May 05, 2017 | staff reporter
NEW YORK (GenomeWeb) – GWG Holdings, the parent company of life insurance
firm GWG Life, announced today that it has exclusively licensed technology
from... 阅读全帖 |
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