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全部话题 - 话题: gene
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y****g
发帖数: 36950
1

哈哈哈哈哈哈,你又输了,人类已经意识到保护动物的重要性了,野生孔雀是国家级保
护动物,不可以乱杀。会被大陆公安抓去坐牢的。
另外你不要信口开河孔雀的天敌被人捕杀完了。没有科学依据。还有人因为孔雀毛好看
而养殖孔雀观赏呢,所以人类社会对自然的破坏或者保护并不属于进化论里的天敌范畴。
是你东扯西扯暴露你的无知的,我是在谈论男女有别,男人创造力比女性强。而你跳出
来扯到什么创造力冒险精神让人死的早,还扯什么到什么鸟玩意,我是教育你要多读书
才费心写了这些帖子,你不用谢我了,我这算是对你的人道关怀。
至于蝴蝶我是在告诉你无毒的动物用鲜艳的色彩和图案作为保护色来恐吓敌人的事实。
死的早也是创造力强。死不死和你没关系。哈哈哈
另外,看看人家的论文质疑你的所谓的性择论:
http://www.answersingenesis.org/articles/tj/v15/n2/peacock
Problems with the theory of sexual selection
If future experiments show that there are no preference genes ... 阅读全帖
t******n
发帖数: 2939
2
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purity (purity) 于 (Wed Aug 17 00:41:32 2011, 美东) 提到:
看到一些猪头男一直在网上说女人不如男人,智力创造力不如男人,
说什么几千年历史证明男人才是社会的强者。
女人之所以弱,无非是因为生育和培养下一代花费太多精力,
怀孕生小孩,对女人来说,就像走过一回鬼门关,
照料下一代女人更是付出无数心血。
要是女人的身体结构如男人般强壮,也不用生育照顾孩子,
跟男人一样把时间精力花在事业上,很多男人会哭,
比起脑袋灵敏度,学习能力,很多男人不如女人。
☆─────────────────────────────────────☆
yugong (愚公挖坑) 于 (Wed Aug 17 01:13:48 2011, 美东) 提到:
我觉得你没有弄清楚为什么,你学数理化是为学而学,这样属于专业培训,老师好,人
聪明勤奋,肯定能拿奖。但是容易高分低能。
但是在复杂的社会环境里事业有成需要创造力,也就是要触类旁通,或者为了应用而学
。你觉得自己够聪明,数理化... 阅读全帖
s********n
发帖数: 26222
3
方舟子在此文中说“虫子不吃的, 人能吃吗”是中国人的质疑, 而美国人是不会问这
样的问题的, 这显然是骗人的。见下文和其中引用的文献, 其中不少是美国人的科研

"Comments on the human health impact of Bacillus thuringiensis toxin gene
product in genetically modified crops"
EPA Review Docket Number OPP-00678B
Professor Joe Cummins
Professor Emeritus of Genetics
University of Western Ontario
I have studied the Environment Protection Agency (EPA) document "Bt Plant-
Pesticides Biopesticides Registration Action Document B. HUMAN HEALTH
ASSESSMENT" and comment in the following ... 阅读全帖
T**********e
发帖数: 29576
4
人类基因不能专利, 但是cDNA可以专利。这个决定很让人奇怪。
A victory for genes
Nature Medicine (2013)
he decision has been a long time in coming—so long that Myriad's patents
were due to expire in less than three years. And the 15-year delay has
surely not aided patients who frequently benefit from healthy competition in
the biotech sector or from research on BRCA genes. Yet the decision brings
relief to those of us who reject the idea that an individual or corporation
can own—even for a limited time—human genes and there... 阅读全帖
c*******u
发帖数: 12899
5
来自主题: NextGeneration版 - [合集] 男孩智力真的只遗传母亲吗?
☆─────────────────────────────────────☆
karo (karo) 于 (Fri Mar 4 12:21:45 2011, 美东) 提到:
看到这样一篇文章,不知道有没有道理啊?如果是真的,我太伤心了,因为我们家都是
男宝宝,本来指望聪明的爸爸能把智商遗传给他们,现在我这个笨妈不是要害惨我的宝
宝们了。55
http://zhidao.baidu.com/question/5021375
智商的遗传基因ZT
满有意思的^^
据说决定智商的八对基因全部都是位于X 染色体上面,然后男生是XY,
X 是来自母亲,
Y 是来自父亲。
所以男生的智商全部都是来自母亲的遗传。
然后女生是X X,所以女生的智商是父亲跟母亲各有一半影响。
然后说,因为女生的智商是父亲母亲都有影响,所以会有中和的效应。
所以女生智商的分布会呈现自然分布( normaldistribution ),就是倒钟状,中间最
多,两边较少。
然后男生因为是完全只受一方影响,所以男生智商分布会呈现在偏向在两个极端。
也就是说,男生天才比较多,但是同时,蠢材之中也是男生特别多。
这个故... 阅读全帖
l******a
发帖数: 16364
6
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spectrum805 (spectrum805) 于 (Tue Sep 27 01:20:44 2011, 美东) 提到:
发信人: spectrum805 (spectrum805), 信区: SanDiego
标 题: Re: 加州政府未得人民同意, 通過了一項 SB48 法 律 (转载)
发信站: BBS 未名空间站 (Tue Sep 27 01:18:30 2011, 美东)
这段录像里提到麻省的父母听到老师给二年级的儿子念一本王子和王子结婚的幸福故事。(录影一分钟左右)。如果你们听到孩子的老师给他们念这样的故事会有什么反应吗?
Amazon link of 《王子和王子》一书
http://www.amazon.com/King-Linda-Haan/dp/1582460612/ref=sr_1_1?
我上次也无意中发现孩子的学校里有这本 Bobby叔叔和Jamie叔叔的婚礼的故事书
http://www.amazon.com/Uncle-Bobbys-Wedding-Sarah-B... 阅读全帖
S*********g
发帖数: 24893
7
大盘涨,大盘跌,大盘涨,大盘跌,大盘涨,大盘跌,大盘涨,大盘跌,大盘涨,大盘
跌,大盘涨,大盘跌,大盘涨,大盘跌,大盘涨,大盘跌,。。。
主席温柔地拔教授的阴毛:gene涨,gene跌,gene涨,gene跌,gene涨,gene跌,gene
涨,gene跌,gene涨,gene跌,gene涨,gene跌,gene涨,gene跌,gene涨,gene跌,
gene涨,gene跌,gene涨,gene跌,gene涨,gene跌,。。。
i*****s
发帖数: 4596
8
来自主题: Military版 - 东亚女胸小的原因找到了
http://www.nytimes.com/2013/02/15/science/studying-recent-human

East Asian Physical Traits Linked to 35,000-Year-Old Mutation
By NICHOLAS WADE
Published: February 14, 2013
Gaining a deep insight into human evolution, researchers have identified a
mutation in a critical human gene as the source of several distinctive
traits that make East Asians different from other races.
The traits — thicker hair shafts, more sweat glands, characteristically
identified teeth and smaller breasts — are the re... 阅读全帖
W*****B
发帖数: 4796
9
全世界只有20几个人
An 11-Year-Old Got Most Of Her Genes From Her Dad, And Almost None From Her
Mom
BuzzFeed News Reporter
An 11-year-old girl from the Czech Republic was born with genes that came
almost entirely from her father, instead of half from each parent.
Only about 25 people in the world — all girls — have been reported with
this genetic syndrome, and the Czech girl appears to be the first to have
inherited it without developing cancer.
“Ten to fifteen years ago, we didn’t think this condition w... 阅读全帖
l****r
发帖数: 230
10
来自主题: NextGeneration版 - 男孩智力真的只遗传母亲吗?
http://discovermagazine.com/2005/oct/sex
Last January Harvard University president Lawrence Summers hypothesized that
women may be innately less scientifically inclined than men. Not long after
the ensuing uproar, researchers announced the sequencing of the human X
chromosome. The project was hailed as a great leap forward in decoding the
differences between men and women, at least from a biological perspective.
While it did nothing to calm the maelstrom swirling around Summers, the new
understa... 阅读全帖
p**********u
发帖数: 15479
11
来自主题: Missouri版 - 东亚女胸小的原因找到了 (转载)
【 以下文字转载自 WaterWorld 讨论区 】
发信人: ldy (现在我很害怕,可能时间会炸), 信区: WaterWorld
标 题: 东亚女胸小的原因找到了
发信站: BBS 未名空间站 (Fri Feb 15 11:11:04 2013, 美东)
发信人: inergas (大坏猪), 信区: Military
标 题: 东亚女胸小的原因找到了
发信站: BBS 未名空间站 (Fri Feb 15 09:21:19 2013, 美东)
http://www.nytimes.com/2013/02/15/science/studying-recent-human

East Asian Physical Traits Linked to 35,000-Year-Old Mutation
By NICHOLAS WADE
Published: February 14, 2013
Gaining a deep insight into human evolution, researchers have identified a
mutation in a critic... 阅读全帖
l*y
发帖数: 21010
12
来自主题: Fashion版 - 东亚女胸小的原因找到了
【 以下文字转载自 Military 讨论区 】
发信人: inergas (大坏猪), 信区: Military
标 题: 东亚女胸小的原因找到了
发信站: BBS 未名空间站 (Fri Feb 15 09:21:19 2013, 美东)
http://www.nytimes.com/2013/02/15/science/studying-recent-human

East Asian Physical Traits Linked to 35,000-Year-Old Mutation
By NICHOLAS WADE
Published: February 14, 2013
Gaining a deep insight into human evolution, researchers have identified a
mutation in a critical human gene as the source of several distinctive
traits that make East Asians different from other races.... 阅读全帖
a*******s
发帖数: 117
13
自然发生的跨远距离物种基因转移举例:
病毒基因转移到哺乳动物,包括人类
PNAS(2012)
Ancestral capture of syncytin-Car1, a fusogenic endogenous retroviral
envelope gene involved in placentation and conserved in Carnivora
ABSTRACT
Syncytins are envelope protein genes of retroviral origin that have been
captured for a function in placentation. Two such genes have already
been identified in simians, two distinct, unrelated genes have been
identified in Muridae, and a fifth gene has been identified in the
rabbit. Here, we searched for s... 阅读全帖
l*y
发帖数: 21010
14
来自主题: WaterWorld版 - 东亚女胸小的原因找到了
【 以下文字转载自 Military 讨论区 】
发信人: inergas (大坏猪), 信区: Military
标 题: 东亚女胸小的原因找到了
发信站: BBS 未名空间站 (Fri Feb 15 09:21:19 2013, 美东)
http://www.nytimes.com/2013/02/15/science/studying-recent-human

East Asian Physical Traits Linked to 35,000-Year-Old Mutation
By NICHOLAS WADE
Published: February 14, 2013
Gaining a deep insight into human evolution, researchers have identified a
mutation in a critical human gene as the source of several distinctive
traits that make East Asians different from other races.... 阅读全帖
m**e
发帖数: 857
15
Genetically modified athletes: Forget drugs. There are even suggestions some
Chinese athletes' genes are altered to make them stronger。
By John Naish
PUBLISHED: 19:28 EST, 31 July 2012
Read more: http://www.dailymail.co.uk/news/article-2181873/Genetically-modified-athletes-Forget-drugs-There-suggestions-Chinese-athletes-genes-altered-make-stronger.html#ixzz22eomrirj
The controversy over Chinese swimmer Ye Shiwen’s astonishing gold medal
performance this week is no longer confined to just the sus... 阅读全帖
w*****t
发帖数: 179
16
来自主题: Immigration版 - Review Opportunity in Biosensoring Field
您好,不知道我的背景能否审到这片文章。我曾经审过一些小杂志,希望能够对我争取
这次机会有所帮助。详细的CV和研究背景如下。非常感谢您的考虑。我的工作邮箱:
z****[email protected]
好像CV在这里粘贴很难看,不好意思。前一段时我的CV,后一段我的较详细的研究经历
。如有需要我更详细的背景情况,请跟我发信。
1
CURRICULUM VITAE
Full Name: Zhimin Wang
Address: Allegheny-Singer Research Institute, West Penn Allegheny, Health
System, South Tower, 320 East North Avenue, Pittsburgh, PA 15212-4772
Phone: 412-359-6153 (Office)
412-737-3777 (Cell)
E-mail: z****[email protected] w************[email protected]
EDUCATION
September, 2001- May, 2005 Ph.D., Molecular M... 阅读全帖
w*****t
发帖数: 179
17
来自主题: Immigration版 - 需要reviewer, 微生物方向杂志
hello, thank you for providing the information. Please find my CV below and
my research experience. I have been revewing for over 10 journals for 14
times. My majour of PH.D is microbiology from Wuhan university. I have
published several papers concering virology and bacterial infection. So far
my work also foucse on salivary gland biofilm formation under LL37 and K4s4
treatment. If you need further information, please let me know. My email
address: z****[email protected]
Thank you for your time and c... 阅读全帖
s******y
发帖数: 28562
18
美国高等法院今日裁定,在自然界自然存在的人类基因不能作为专利。
http://news.yahoo.com/court-says-human-genes-cannot-patented-14
Court says human genes cannot be patented
Associated PressBy JESSE J. HOLLAND | Associated Press – 5 mins ago

WASHINGTON (AP) — The Supreme Court ruled Thursday that companies cannot
patent parts of naturally-occurring human genes, a decision with the
potential to profoundly affect the emerging and lucrative medical and
biotechnology industries.
The high court's unanimous judgment reverses three de... 阅读全帖
w***n
发帖数: 4358
19
来自主题: Hubei版 - [合集] 关于热干面
☆─────────────────────────────────────☆
yk7209 (gene) 于 (Sun Aug 1 23:10:52 2010, 美东) 提到:
大家觉得老美会喜欢热干面的口味吗?会不会觉得太干?如果加点肉酱如何?
欢迎建议,谢谢!
☆─────────────────────────────────────☆
somekiss (放开那个姑娘!) 于 (Sun Aug 1 23:12:31 2010, 美东) 提到:
不會,出了武漢都不見得有幾個人喜歡吃。

☆─────────────────────────────────────☆
thelishier (u r my angel) 于 (Sun Aug 1 23:14:16 2010, 美东) 提到:
肯定不喜欢
外地人都需要很久接受,芝麻酱味道非常strong,我都是到大学才开始喜欢吃的
☆─────────────────────────────────────☆
Viaaa (大V) 于 (Sun Aug 1 23:14:37 2010, 美... 阅读全帖
j*p
发帖数: 411
20
本人在wet lab里面做纯数据分析,for NGS data analysis, 简单介绍一些自己接触过
,并且觉得挺有用的工具,说的有点杂,权作抛砖引玉,还请不吝赐教。
Next-Gen sequencing(NGS)和现在正在发展的3rd-gen sequencing将会在生物学研究中
被越来越广泛应用。不管你信不信,反正我信了。一是基于实验成本的降低($1k
whole-genome sequencing is coming),越来越多的实验室可以操作;二是可以提供
相对low throughput experiment多的多的数据和信息,可以看到很多从前看不到的东
西;三是sequencer本身对测序的准确性正在逐渐提高,所以实验固有错误率降低;四
是各种算法的成熟应用,这使得很多由于实验产生的误差在出数据后通过对数据的分析
得以过滤。按照library preparation来分,NGS主要有DNA-seq和RNA-seq
DNA-seq is usually used as ChIP-seq to study transcription factor(TF)-DNA
bi... 阅读全帖
j*p
发帖数: 411
21
本人在wet lab里面做纯数据分析,for NGS data analysis, 简单介绍一些自己接触过
,并且觉得挺有用的工具,说的有点杂,权作抛砖引玉,还请不吝赐教。
Next-Gen sequencing(NGS)和现在正在发展的3rd-gen sequencing将会在生物学研究中
被越来越广泛应用。不管你信不信,反正我信了。一是基于实验成本的降低($1k
whole-genome sequencing is coming),越来越多的实验室可以操作;二是可以提供
相对low throughput experiment多的多的数据和信息,可以看到很多从前看不到的东
西;三是sequencer本身对测序的准确性正在逐渐提高,所以实验固有错误率降低;四
是各种算法的成熟应用,这使得很多由于实验产生的误差在出数据后通过对数据的分析
得以过滤。按照library preparation来分,NGS主要有DNA-seq和RNA-seq
DNA-seq is usually used as ChIP-seq to study transcription factor(TF)-DNA
bi... 阅读全帖
l**********1
发帖数: 5204
22
BGI or others just try
NGS with both blood samples Ye Shiwen and Katie Ledecky
plus below six athletes total 8 athletes
performance profiling”方法,将所有国际上
有名的现役游泳运动员的比赛成绩,进行profiling分析,发现最高分排名(也就是最
“anomalous”的排名)是:
1. Elizabeth Beisel
2. Michael Phelps
3. Rebecca Adlington
4. Ian Thorpe
5. Stephanie Rice
6. Allison Schmitt
while can find proof of her EPOR mutation which is identical to Finnish
cross-country skier Eero Mäntyranta
and also is different to former matchs any DNA samples Ge... 阅读全帖
c********n
发帖数: 225
23
【记录历史】谁重复验证了NgAgo?
项目 结题
date: 2017年8月2日
updated: 2017年8月4日
Note2017080401: added a few notable reviews/summaries
---------------------------------------
- NBT retraction note:
http://www.nature.com/nbt/journal/v34/n7/full/nbt.3547.html#correction2
原文引用
“Retracted online 02 August 2017
We are retracting our study because of the continued inability of the
research community to replicate the key results in Figure 4, using the
protocols provided in our paper. In this figure we report that the
Natro... 阅读全帖
c**i
发帖数: 265
24
来自主题: Biology版 - Nature News: The controversy over NgAgo
http://www.nature.com/news/replications-ridicule-and-a-recluse-the-controversy-over-ngago-gene-editing-intensifies-1.20387
Replications, ridicule and a recluse: the controversy over NgAgo gene-
editing intensifies
As failures to replicate results using the CRISPR alternative stack up, a
quiet scientist stands by his claims.
David Cyranoski
08 August 2016
SHIJIAZHUANG, CHINA
A controversy is escalating over whether a gene-editing technique proposed
as an alternative to the popular CRISPR–Cas9 sys... 阅读全帖
g******t
发帖数: 230
25
http://www.nytimes.com/pages/health/research/index.html
Scientists Link Gene Mutation to Autism Risk
Kevin P. Casey for The New York Times
Teams of scientists working independently have for the first time identified
several gene mutations that they agree sharply increase the chances that a
child will develop autism. They have found further evidence that the risk
increases with the age of the parents, particularly in fathers over age 35.
The gene mutations are extremely rare and together account ... 阅读全帖
L******r
发帖数: 141
26
来自主题: Immigration版 - 怎样写好推荐信 EB1A/B
All the materials were taken from Administrative Decisions (Aliens with Extraordinary Ability/ Outstanding Professors and Researchers). 所以这些话是权威!!!
I downloaded All the AAO decisions for the past three years. I read one by one for a total number of more than 200 decisions. I took good paragraphs from recommendation letters which IOs thought have met criterion of contribution. Because the works were from PDF files, I had to reformat them into word file.
It took me many hours to do the work and I... 阅读全帖
s******y
发帖数: 28562
27
David Venet from the Université Libre de Bruxelles 用胡乱挑选的基因组合
和已经发表的所谓的癌基因的marker 用在未知的病人的数据上,发现胡乱挑选
的基因的准确率比那些所谓的marker 还要好。
文章结尾直接点了几个杂志的名:Cell, Nature Genetics, PNAS, 认为这些杂志
过分鼓吹所谓的 gene marker 的意义。从文章里面的行文来看,估计这些也是
把这个文章据掉的杂志 (lol)
文章最后发表在
PLoS Comput Biol. 2011 Oct;7(10):e1002240. Epub 2011 Oct 20.
http://blog.f1000.com/2012/01/10/random-gene-sets-can-predict-b
Random gene sets can predict breast cancer survival better than cancer-
related signatures
And top-tier journals did not want to pu... 阅读全帖
s******y
发帖数: 28562
28
David Venet from the Université Libre de Bruxelles 用胡乱挑选的基因组合
和已经发表的所谓的癌基因的marker 用在未知的病人的数据上,发现胡乱挑选
的基因的准确率比那些所谓的marker 还要好。
文章结尾直接点了几个杂志的名:Cell, Nature Genetics, PNAS, 认为这些杂志
过分鼓吹所谓的 gene marker 的意义。从文章里面的行文来看,估计这些也是
把这个文章据掉的杂志 (lol)
文章最后发表在
PLoS Comput Biol. 2011 Oct;7(10):e1002240. Epub 2011 Oct 20.
http://blog.f1000.com/2012/01/10/random-gene-sets-can-predict-b
Random gene sets can predict breast cancer survival better than cancer-
related signatures
And top-tier journals did not want to pu... 阅读全帖
C*I
发帖数: 4736
29
相比较而言,石正丽的《Bat origin of human coronaviruses/蝙蝠是人类冠状病毒的
来源》是扎扎实实的抓蝙蝠,解剖蝙蝠,分离病毒,对比DNA,RNA后得出得结论。
请lobbock读一读,说一说,走两步!
http://virologyj.biomedcentral.com/articles/10.1186/s12985-015-0422-1
Review
Open Access
Published: 22 December 2015
Bat origin of human coronaviruses
Ben Hu, Xingyi Ge, Lin-Fa Wang & Zhengli Shi
Virology Journal volume 12, Article number: 221 (2015) Cite this article
Abstract
Bats have been recognized as the natural reservoirs of a large variety of
viruses. Special attention has ... 阅读全帖
d*b
发帖数: 4184
30
来自主题: USANews版 - 里把肉们进来反驳吧
Leftist Lies Destroyed as Scientists Discover the Gene Which Causes Brain
Size and Intelligence
JULY 31, 2013 BY TNO STAFF— IN SCIENCE
Nearly 100 years of leftist lies and deception, which has claimed that
intelligence is not genetic, has been destroyed by the science of genetics.
According to a new study, just published in the University of California Los
Angeles (UCLA) newsroom, scientists have definitively found the genes which
control brain size and intelligence.
Even worse for liberals, ... 阅读全帖
l******a
发帖数: 16364
31
☆─────────────────────────────────────☆
break8811 (池蛙) 于 (Thu Nov 8 15:06:11 2012, 美东) 提到:
我最近才开始了解自闭症。一些不成熟的想法抛出来,请大家指正。
Autistic disorder(严重自闭症)和ASD(autism spectrum disorder,泛自闭症,也包
含Autistic disorder)都是受遗传影响,神经系统发育不全而导致的语言社交能力障碍
。ASD很多症状和汞中毒接近,但后者不是遗传导致的。诊断ASD时都要排除汞中毒的可
能。
ASD和正常小孩之间其实没有明显的界限,本来"正常"就只有统计学意义。很多被诊断
为ASD的小孩的神经发育,只是比较缓慢而已,只要父母有耐心,更大点之后小孩就正
常了。但也有很多ASD小孩的神经系统,如果不人工干预,就永远无法发育正常--其实
即使人工干预,也往往只能做点改善,难以完全正常。
说到这儿,我觉得有必要引入“基因表达”的概念。曾看过一篇报导(对不起原文找不
到了),说某个村庄的风俗,小孩老绑着不让到处跑,导致当地人群的... 阅读全帖
c*******o
发帖数: 27734
32
☆─────────────────────────────────────☆
bixu1 (2-39) 于 (Tue Mar 8 22:52:02 2011, 美东) 提到:
外省的男生女生到了北京的大学里,人生地不熟的,学习压力也大,没有什么朋友,大
家心里都慌里慌张的。唯有北京男生,呼朋唤友,中学同学在学校各系都有。更为可气
的是,外省的漂亮女生到了大三基本上都跟了一个或者几个北京男生做男女朋友,可能
是想找个北京的家庭作依靠,在北京留下发展。包括北京萧条的区比如丰台区,石景山
区和通县的男生,也有所获,找个南方省的女生做朋友。很多北京男生人长得很丑,成
绩也很差,但是也能先得月,捞个漂亮的四川/安徽/江西/湖南/广西/云南//贵州/湖北
/河南的女孩子,有时我看着真好笑,觉得鲜花叉在牛粪上。
现在我才意识到,其实还是地区经济发展不平衡造成的差距,经济落后省份的女生
盲目崇拜北京的男生,包括北京郊区和县里的男生,认为凡是北京地区的男生家庭
都有钱有权。
外省的男生也受到不少北京男生的歧视。就像美国人歧视中国留学生一样。
其实,江浙沪深圳广州的女生基本看不上北京男生,南... 阅读全帖
l**********1
发帖数: 5204
33
来自主题: Biology版 - 请教一个基础问题
only for paralogous
please go to
//www.ncbi.nlm.nih.gov/pubmed/15865991
its page one:
What is paralogy?
Since Darwin, for most biologists (or at least, for evolutionary biologists) homology has
come to mean something like ‘similarity due to common descent’, to distinguish it from
similarity due to convergent evolution. An accurate understanding of the relationships
between living things depends upon correctly identifying homologous characteristics of
an organism from other similarity. A classic ... 阅读全帖
s****l
发帖数: 10462
34
有人愿意讨论这里面提及的测序技术吗?优缺点,可行性,第一手经验等等
这里面谁现在是赢家很清楚,但是可见的将来和更远的将来谁会赢?
http://cen.acs.org/articles/92/i33/Next-Gen-Sequencing-Numbers-
全文拷贝如下
试试看图能不能贴上
/1407973177171.jpg
/1408028636124.jpg
OVER STORY
Next-Gen Sequencing Is A Numbers Game
As technical and cost barriers fall, instrument firms move their systems
into research and clinical markets
By Ann M. Thayer
Department: Business
Keywords: instrumentation, gene sequencing, diagnostics, genomics, cancer
[+]Enlarge
09233-cover-Openercxd_17647969-690
A... 阅读全帖
r******0
发帖数: 357
35
来自主题: Biology版 - 枪手公司的末日
BMC终于在最近做了一件值得尊敬的事情。我敢说下面的狗屎99%都是所谓的个性化生物
“信息”“润色”的畸形怪胎。一般以所谓的Meta分析或者随便下载一套狗屎基因芯片
数据,然后做一些似是而非的烂分析,发一堆垃圾,一篇文章卖给忙于召妓的医生5万
到10万。
1.
Retraction Note Open Access
Retraction Note: Impact of guidewire selection and operator expertise on
radiation exposure in transradial angiography
Jianmin Yang, Ningfu Wang, Xiaoshan Tong, Xianhua Ye, Liang Zhou, Guoxin
Tong, Yun Shen, Shuzheng Lv
Journal of Cardiothoracic Surgery 2015, 10:42 (27 March 2015)
Full text | PDF
2.
Retraction Note Open Access
Retracti... 阅读全帖

发帖数: 1
36
来自主题: Biology版 - GTex portal dataset download
On your computer with web browser
1. go to https://www.gtexportal.org/home/datasets
2. You will be asked to login, so login with your google account
3. open developer console, run
"gapi.auth2.getAuthInstance().currentUser.get().getAuthResponse().id_token"
4. Copy this token
On your Linux command line
5. run the following command to obtain the URL for each of the file, replace
XXX with the token
curl -X GET https://gtexportal.org/rest/v1/admin/file_download?objectPath=
gtex_analysis_pilot_v3/rna_... 阅读全帖

发帖数: 1
37
来自主题: Biology版 - GTex portal dataset download
On your computer with web browser
1. go to https://www.gtexportal.org/home/datasets
2. You will be asked to login, so login with your google account
3. Randomly choose a small file to download (such as "GTEx_Analysis_v7_
Annotations_SubjectPhenotypesDD.xlsx"), this is to trigger the
authentication process
4. open developer console, run
"gapi.auth2.getAuthInstance().currentUser.get().getAuthResponse().id_token"
5. Copy this token
On your Linux command line
6. run the following commands to obtain ... 阅读全帖
f**d
发帖数: 768
38
来自主题: Neuroscience版 - eBook: From computer to brain
这是一本计算神经科学的优秀著作,全文拷贝这里(图和公式缺),有兴趣的同学可以
阅读
如需要,我可以分享PDF文件(--仅供个人学习,无商业用途)
From Computer to Brain
William W. Lytton
From Computer to Brain
Foundations of Computational Neuroscience
Springer
William W. Lytton, M.D.
Associate Professor, State University of New York, Downstato, Brooklyn, NY
Visiting Associate Professor, University of Wisconsin, Madison
Visiting Associate Professor, Polytechnic University, Brooklyn, NY
Staff Neurologist., Kings County Hospital, Brooklyn, NY
In From Computer to Brain: ... 阅读全帖
C*I
发帖数: 4736
39
一直在误导,现在还在误导。 说说明corona virus 不可以从蝙蝠直接传染给人,必须
经过一个中间宿体性的其它动物才能传染给人。所以,病毒发生后,就故意误导全国人
民去海鲜市场找证据,找其它野生动物的麻烦。 而且还是病毒所去找的,找完了还装
模做样化验呀,分离呀什么的。最后把责任全部推给了海鲜市场的动物。可是那种动物
,一直不敢说,说了其它相关已经在人就会去早那种动物监测。 所以压根不说,打马
虎眼。
事实上,早在2013 年,就是这个武汉病毒研究所,已经从来自云南的蝙蝠身上所携带
的corona virus中分离出第一株蝙蝠SARS类似样的冠状病毒的活病毒,其中就包含了类
似于S类型的基因。从而证实这株病毒能够使其接受和SARS病毒相同的受体,并能够感
染人的细胞。对此新发现,武汉病毒所还把它以武汉病毒研究所的英文简称命名“WIV1
”,以彰显这一发现的重要价值和属于自己第一个发现的巨大研究成果。这个成果刊载
于2013年11月的《自然》杂志。
就是说,从云南弄回来的这种蝙蝠所携带的类似于sars的 corona virus, 可以不经过
其它受体/宿体,而直接传染给人。 他们... 阅读全帖
C*I
发帖数: 4736
40
一直在误导,现在还在误导。 说说明corona virus 不可以从蝙蝠直接传染给人,必须
经过一个中间宿体性的其它动物才能传染给人。所以,病毒发生后,就故意误导全国人
民去海鲜市场找证据,找其它野生动物的麻烦。 而且还是病毒所去找的,找完了还装
模做样化验呀,分离呀什么的。最后把责任全部推给了海鲜市场的动物。可是那种动物
,一直不敢说,说了其它相关已经在人就会去早那种动物监测。 所以压根不说,打马
虎眼。
事实上,早在2013 年,就是这个武汉病毒研究所,已经从来自云南的蝙蝠身上所携带
的corona virus中分离出第一株蝙蝠SARS类似样的冠状病毒的活病毒,其中就包含了类
似于S类型的基因。从而证实这株病毒能够使其接受和SARS病毒相同的受体,并能够感
染人的细胞。对此新发现,武汉病毒所还把它以武汉病毒研究所的英文简称命名“WIV1
”,以彰显这一发现的重要价值和属于自己第一个发现的巨大研究成果。这个成果刊载
于2013年11月的《自然》杂志。
就是说,从云南弄回来的这种蝙蝠所携带的类似于sars的 corona virus, 可以不经过
其它受体/宿体,而直接传染给人。 他们... 阅读全帖
C*I
发帖数: 4736
41
Published: 30 October 2013
Isolation and characterization of a bat SARS-like coronavirus that uses the
ACE2 receptor
Xing-Yi Ge, Jia-Lu Li, Xing-Lou Yang, Aleksei A. Chmura, Guangjian Zhu,
Jonathan H. Epstein, Jonna K. Mazet, Ben Hu, Wei Zhang, Cheng Peng, Yu-Ji
Zhang, Chu-Ming Luo, Bing Tan, Ning Wang, Yan Zhu, Gary Crameri, Shu-Yi
Zhang, Lin-Fa Wang, Peter Daszak & Zheng-Li Shi
Nature volume 503, pages535–538(2013)Cite this article
Abstract
The 2002–3 pandemic caused by severe acute respirator... 阅读全帖
s***l
发帖数: 2236
42
☆─────────────────────────────────────☆
iamtheretoo (iamhereiamthere) 于 (Mon Aug 29 15:34:54 2011, 美东) 提到:
听说美国也有gifted school,我们正在准备买房,有朋友劝我们不用考虑学区,因为
以后女儿可以上gifted school。对女儿的智力很有信心,有疑惑:
这种学校是怎么选拔的?也有考试?
是不是不用自己交钱,比私立学校好吗?
听说会有专门的校车接送孩子,是不是就不用考虑离家远近了?
谢谢!!
☆─────────────────────────────────────☆
mitbbser1 (mitbbser) 于 (Mon Aug 29 15:39:26 2011, 美东) 提到:
不要钱, 是公立系统的一部分. 因材施教, 就和智力落后的孩子需要特殊教育一样.
gifted program具体执行因学区而异, 你得自己在当地打听.
☆─────────────────────────────────────☆
winterlake (冬... 阅读全帖
n********n
发帖数: 8336
43
来自主题: TrustInJesus版 - 创造论讲座1-4ZT
送交者: 职老 2015年10月04日19:26:43
(1)俺们知道,无论是进化论还是创造论,在生命这个层面而言,都是依据同样的科学
依据来解释生命的来源。
唯一不同的是,创造论首先强调的是圣经旧约第一部分:创世纪GENESIS,也可以翻译
成:基因生,因为GENE就是指基因,虽然人类一开始并不知道是DNA或者说DNA承载的密
码信息,SIS这个后坠在生物学中指各种“生”,比如ANGIOGENESIS指血管再生--俺是
这个领域的权威和专家,对此不懂的同学,比如D同学,可以提问,嘿嘿。也就是说,
今天的创造论科学家们并非是平空捏造的,首先他们有神的启示,或者说神的话的记载
。因为旧约的第一部份基因生据信最早写于公园前3000千年,也就是现在5千年前,就
人类的文明记载,这个时期绝对不可能是人类自己觉悟出来的,或者说进化来的知识,
甚至那时最原始的科学都尚不存在。以前有人民怀疑这个古代记载,但后来大量的考古
证明,完全证实了这个年代推断,而且只早不晚,因为最近的7000年前的叙利亚泥板有
类似的亚当夏娃的记载。而且这个时期,中国人民的记载也是神的话时期。所以今日的
创造论科学家包括持I... 阅读全帖
P******l
发帖数: 1648
44
来自主题: TrustInJesus版 - 人类的肤色
WHAT COLOR WAS ADAM?
In western countries, nearly every imaginative painting of Adam and Eve
depict two adult Caucasians with fair skin and blue eyes. These images, even
used as Bible illustrations, tend to shape the reader's mental image of the
first man and woman. The Sunday-school origin of the dark races is often
that they were descendants of Adam and Eve who had migrated to a hot climate
where the suntan eventually became an inherited characteristic. These
images and explanations discredit ... 阅读全帖
l*******1
发帖数: 16217
45
看你们这二道贩子文章 不如看底下英文UC伯克利是怎么耍臭不要脸的
专利局都说了张峰的专利在真核生物中有效 是一个separate case
UC 伯克利还在那意淫要所有细胞类型中的专利 你让美国专利局自己抽自己的脸吗
Appeals board clears way for UC Berkeley to receive patent on CRISPR-Cas9
gene editing
By Robert Sanders, Media relations | FEBRUARY 15, 2017
Click to share on Twitter (Opens in new window)181Click to share on Facebook
(Opens in new window)181Click to share on Google+ (Opens in new window)
Click to share on Reddit (Opens in new window)Click to email this to a
friend (Opens in new window)... 阅读全帖

发帖数: 1
46
来自主题: Military版 - 中国生物医学大跃进,米国烂死
HONG KONG -- At 28, Dai Wenyuan quit his job developing artificial
intelligence software for Chinese internet giant Baidu to launch his own
company. It was a smart move: his AI start-up quickly attracted an initial $
4 million investment from Sequoia Capital China in 2015.
Three years later, Dai's company is capturing attention for developing a
medical tool that uses AI to predict whether patients are at risk of
developing diabetes. His company, 4Paradigm, said its accuracy rate was 88%.
Key to ... 阅读全帖
w********2
发帖数: 632
47
来自主题: Military版 - gmo食品最大的问题
Cellular competency (natural transformation) refers to the active uptake of
free (extracellular) DNA across the cell wall and cell membrane(s) using
cellular machinery designed to facilitate the process (Dubnau, 1999; Lorenz
and Wackernagel, 1994). It is a highly regulated physio- logical state that
is often sensitive to environmental cues (Molin and Tolker-Nielsen, 2003).
When the DNA is her- itably incorporated into the recipient’s genome, the
pro- cess is known as transformation.
Bacterial co... 阅读全帖
c*******u
发帖数: 12899
48
来自主题: NextGeneration版 - [合集] [bssd]我的孩子,我的经历
☆─────────────────────────────────────☆
aprilxu (妞妞是个乖宝宝) 于 (Fri Mar 30 00:33:44 2012, 美东) 提到:
我已经很久很久不发帖了,自从我女儿确诊以后,我就再没有心思在网上发帖和回帖了
。这几天看了一些关于残疾孩子和流产的帖子,我忍不住想说几句我自己的经历,也算
是一种倾诉吧。
我女儿快三岁了,又漂亮又聪明,可是,她不会走路,而且永远也不会。她患有SMA (
Spinal Muscular Atrophy) 。这是一种genetic disorder,由于基因缺失身体无
法制造一种蛋白,严重影响她的运动神经元和所控制的肌肉,导致肌张力低下。SMA是
一种罕见病,发病率仅为万分之一,由于我和我老公都是携带者(我们都不知道,也没
有家族史),我们的孩子有四分之一的几率患病,我的女儿很不幸。
但是幸运的是,我的女儿不是最严重的情况。Type 1,也就是最严重的情况,孩子一般
不会活过两岁。我女儿属于type 2,医生没说能活多久,只是告诉我们,最终依靠仪器
,她也许能活到成年,能上college,但是... 阅读全帖
M********s
发帖数: 104
49
来自主题: Immigration版 - NIW 申请推荐信模板
以前网上淘到的一个,
College of _____
Department of __________
XXX ____ Avenue, 7th Floor
(city), (State) (zip) (推荐人地址)
August 12, 2007
U.S. Citizenship & Immigration Services
Nebraska Service Center
850 “S” Street Lincoln, NE 68508
Re: Dr. ____ ___ (your full name)
Dear Sir/Madam,
I strongly support the National Interest Waiver application for ______ ___,
M.D, Ph.D.. Dr. ___ is an extraordinary young scientist who is making
significant contributions to our understanding of ... 阅读全帖
w*****t
发帖数: 179
50
来自主题: Immigration版 - 另一个审稿机会
Thank you for providing the review opportunity, I have been working in the
molecular biology for over 15 years and published some papers in journals
like Journal of Cell Biology, Journal of General Virology et al., . Also I
have reviewed over 20 manuscripts for 10 journals. Hopefully these
experiences will help me to catch this opportunity. If you need further
detail information regarding my qualification, please let me know (zwang1@
wpahs.org). Please find my CV below. Thanks a lot.
Zhimin Wang... 阅读全帖
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