t*******y
发帖数: 4 | 1 办绿卡用
关键词： chemical biology, protein chemistry, heme protein, enzymatic
catalysis, bioinorganic/biophysical chemistry, bio-organic chmistry
已经审过2篇杂志，站内联系，提供cv
大家多帮帮忙！ |
|
|
s*******s
发帖数: 623 | 3 Job ID: GF2012A001
Posting Title: Research Scientist/Research Associate/Electrobiochemist
Brief Introduction of Gate Fuels Inc.:
“Imagination, Innovation, Implementation --- Enabled Technologies for a
Green Clean World”
Gate Fuels Inc. is a research start-up firm based in Blacksburg, VA, with
the goal of developing microbial and cell-free platform technologies that
enable low-cost production of biochemicals, biofuels and electricity. The
first platform is based on industrially-safe Bacillus subt... 阅读全帖 |
|
s*******s
发帖数: 623 | 4 Job ID: GF2012A001
Posting Title: Research Scientist/Research Associate/Electrobiochemist
Brief Introduction of Gate Fuels Inc.:
“Imagination, Innovation, Implementation --- Enabled Technologies for a
Green Clean World”
Gate Fuels Inc. is a research start-up firm based in Blacksburg, VA, with
the goal of developing microbial and cell-free platform technologies that
enable low-cost production of biochemicals, biofuels and electricity. The
first platform is based on industrially-safe Bacillus subt... 阅读全帖 |
|
z*h
发帖数: 773 | 5 Protein engineering and Innovative Biomanufacturing
Our mission is to integrate engineering design principle with biology and
chemistry to solve the most challenging tasks in the sustainability
revolution, such as, terminating the age of crude oil by using renewable
energy, feeding the world with minimum environmental footprints, powering
smart phones by metal-free batteries, etc. We propose to use in vitro
synthetic enzymatic pathways for low-cost biomanufacturing of a lot of
products from biof... 阅读全帖 |
|
P******e
发帖数: 129 | 6 Responsibilities:
The successful candidate will join a dynamic team and be responsible for
analyzing a variety of enzyme containing complex mixtures and characterizing
the enzyme and certain non-enzymatic components.
• Conduct enzymatic screening assays, and reliable determinations
of enzymatic activities in a variety of samples to support new enzyme
discovery;
• Develop and optimize various biochemical assays;
• Demonstrate the ability to correctly analyze and interpr... 阅读全帖 |
|
P******e
发帖数: 129 | 7 If you are interested, please contact me. Thanks,
Responsibilities:
The successful candidate will join a dynamic team and be responsible for
analyzing a variety of enzyme containing complex mixtures and characterizing
the enzyme and certain non-enzymatic components.
• Conduct enzymatic screening assays, and reliable determinations
of enzymatic activities in a variety of samples to support new enzyme
discovery;
• Develop and optimize various biochemical assays;
• Demons... 阅读全帖 |
|
P******e
发帖数: 129 | 8 Responsibilities:
The successful candidate will join a dynamic team and be responsible for
analyzing a variety of enzyme containing complex mixtures and characterizing
the enzyme and certain non-enzymatic components.
• Conduct enzymatic screening assays, and reliable determinations
of enzymatic activities in a variety of samples to support new enzyme
discovery;
• Develop and optimize various biochemical assays;
• Demonstrate the ability to correctly analyze and interpr... 阅读全帖 |
|
|
z*h
发帖数: 773 | 10 Of course 二三流的杂志Editor judge 科学家 is 一流 nor not. It is a silly
system. Give you an example, our paper on conversion of cellulose to starch
was rejected by Nature and Science without review. It will be one of the
most important breakthroughs in the human history.
See the PNAS paper http://www.pnas.org/content/early/2013/04/12/1302420110
Abstract
The global demand for food could double in another 40 y owing to growth in
the population and food consumption per capita. To meet the world’s future
food... 阅读全帖 |
|
f**********r
发帖数: 18251 | 11 【 以下文字转载自 Military 讨论区 】
发信人: wep (买不到鸡蛋了！), 信区: Military
标 题: Re: 林宝红到底是去上海哪个学校赚卖国钱 (转载)
发信站: BBS 未名空间站 (Tue Dec 3 02:21:21 2013, 美东)
上海交大
http://www.pibb.ac.cn/pibbcn/ch/reader/view_abstract.aspx?file_
中文关键词: 普适酶反应速率方程,动力学模型,系统生物学,酶动力学
英文关键词:generic enzymatic rate equation kinetic model systems biology
enzyme kinetics
基金项目:国家重点基础研究发展计划(973)资助项目(2010CB529200, 2007CB914700)
作者 单位 E-mail
徐岷涓 上海交通大学系统生物医学研究院，系统生物医学教育部重点实验室，上
海 200240 m*******[email protected]
朱晓梅 GenMath, Corp.... 阅读全帖 |
|
O**********0
发帖数: 61 | 12 ☆─────────────────────────────────────☆
BHistory (往者的影子) 于 (Fri Sep 9 00:20:11 2011, 美东) 提到:
俺曾认为生命是进化起源的，后来越找越发现进化论像是信仰而非科学结论。可是每有
飞机网友觉着俺如此看待进化论是反科学了。
所以俺本着科学的精神，问个问题，求各位飞机进化论牛人给个科学的答案。
大家知道达尔文进化论是以遗传机制为基础的，第一个有遗传机制的生命怎么来的，当
时根本没有提及。
后人发现这一问题后，就又提出了化学进化论，就是无机分子在某种机制下，自动组合
出了第一个有遗传的生命。此后达尔文进化论似乎可以take care（其实未必，今后再
讨论）。
今天我们先看比第一个有遗传生命的出现简单万亿倍的问题，第一个蛋白质如何化学进化出
现？
先亮亮俺一个愚昧基督徒的愚见：
已知最简单的具有遗传机制的单细胞生命的复杂度已经远远超出人们最初的想象，大概
有400种蛋白质几十万个组成。其中较小的蛋白质大概100个氨基酸，如果在随机热运动
中组成，因为自然界对称的氨基酸不少于40种（20多种氨基酸及... 阅读全帖 |
|
z*h
发帖数: 773 | 13 Abstract
The global demand for food could double in another 40 y owing to growth in
the population and food consumption per capita. To meet the world’s future
food and sustainability needs for biofuels and renewable materials, the
production of starch-rich cereals and cellulose-rich bioenergy plants must
grow substantially while minimizing agriculture’s environmental footprint
and conserving biodiversity. Here we demonstrate one-pot enzymatic
conversion of pretreated biomass to starch through a ... 阅读全帖 |
|
z*h
发帖数: 773 | 14
==> Current power density is still lower than directed methanol fuel cell
but far higher than theoretical power output of microbial fuel cells. The
maximum power density of sugar battery could be increased by 100 folds by
integration of several things together. It is why we never work on microbial
fuel cells.
and bio-active electrode, i.e. conductive bio-enzyme mimic structure or
==> No one claim that sugar biobattery is new. In this paper, we have two
things new:
(1) the first complete oxidati... 阅读全帖 |
|
f**********r
发帖数: 18251 | 15 【 以下文字转载自 Military 讨论区 】
发信人: wep (买不到鸡蛋了！), 信区: Military
标 题: Re: 林宝红到底是去上海哪个学校赚卖国钱 (转载)
发信站: BBS 未名空间站 (Tue Dec 3 02:21:21 2013, 美东)
上海交大
http://www.pibb.ac.cn/pibbcn/ch/reader/view_abstract.aspx?file_
中文关键词: 普适酶反应速率方程,动力学模型,系统生物学,酶动力学
英文关键词:generic enzymatic rate equation kinetic model systems biology
enzyme kinetics
基金项目:国家重点基础研究发展计划(973)资助项目(2010CB529200, 2007CB914700)
作者 单位 E-mail
徐岷涓 上海交通大学系统生物医学研究院，系统生物医学教育部重点实验室，上
海 200240 m*******[email protected]
朱晓梅 GenMath, Corp.... 阅读全帖 |
|
z*h
发帖数: 773 | 16 【 以下文字转载自 ECUST 讨论区 】
发信人: zyh (CH2O), 信区: ECUST
标 题: From nonfood biomass to starch
发信站: BBS 未名空间站 (Mon Apr 15 18:26:35 2013, 美东)
Abstract
The global demand for food could double in another 40 y owing to growth in
the population and food consumption per capita. To meet the world’s future
food and sustainability needs for biofuels and renewable materials, the
production of starch-rich cereals and cellulose-rich bioenergy plants must
grow substantially while minimizing agriculture’s environmenta... 阅读全帖 |
|
z*h
发帖数: 773 | 17 【 以下文字转载自 Chemistry 讨论区 】
发信人: zyh (CH2O), 信区: Chemistry
标 题: From nonfood biomass to starch (转载)
发信站: BBS 未名空间站 (Mon Apr 15 18:28:25 2013, 美东)
发信人: zyh (CH2O), 信区: ECUST
标 题: From nonfood biomass to starch
发信站: BBS 未名空间站 (Mon Apr 15 18:26:35 2013, 美东)
Abstract
The global demand for food could double in another 40 y owing to growth in
the population and food consumption per capita. To meet the world’s future
food and sustainability needs for biofuels and renewable materials, the
production of ... 阅读全帖 |
|
z*h
发帖数: 773 | 18 【 以下文字转载自 ECUST 讨论区 】
发信人: zyh (CH2O), 信区: ECUST
标 题: From nonfood biomass to starch
发信站: BBS 未名空间站 (Mon Apr 15 18:26:35 2013, 美东)
Abstract
The global demand for food could double in another 40 y owing to growth in
the population and food consumption per capita. To meet the world’s future
food and sustainability needs for biofuels and renewable materials, the
production of starch-rich cereals and cellulose-rich bioenergy plants must
grow substantially while minimizing agriculture’s environmenta... 阅读全帖 |
|
b*******t
发帖数: 33714 | 19 ppt直接导出来的，格式有点乱，不过有耐心的话看看还挺有意思的。
==================================
Part 3: Arts and Methods of Kitchen Arts
TOPIC: MEAT
Cooking meat
Cooking meat is all about producing the right texture and flavours.
Texture concerns the structure of meat.
Flavours are all about chemistry –the Maillard reaction.
Components of muscle
Water: 75%
Protein: 18%
Fat: ~4-10%, varies among different types of meat
Carbohydrate: just over 1%
Vitamins, minerals, various organic compounds…
Sliding-filament model of muscle... 阅读全帖 |
|
s***z
发帖数: 631 | 20 请问各位给孩子用CRT的父母，你们用什么护理液？
我们的OD推荐的是 Bausch+Lomb Boston Simplus Multi-Action Solution 和 One
Step Liquid Enzymatic Cleaner （protein remover)。
我们一直在附近的walmart买（没注意到其他地方卖）。但是最近好像他们不在上货了
。于是想看看有没有可替代的护理液。google没有发现有用的结果。
我们每天清洗时是先用盐水冲一遍，然后放入simplus solution，滴一滴enzymatic
cleaner。你们也是类似的吗？ |
|
|
|
|
|
t*******d
发帖数: 2570 | 25 Orig Life Evol Biosph. 2008 Feb;38(1):57-74. Epub 2007 Nov 16.
Lipid-assisted synthesis of RNA-like polymers from mononucleotides.
Rajamani S, Vlassov A, Benner S, Coombs A, Olasagasti F, Deamer D.
Source
Department of Chemistry and Biochemistry, University of California, Santa
Cruz, CA 95064, USA.
Abstract
A fundamental problem in research on the origin of life is the process by
which polymers capable of catalysis and replication were produced on the
early Earth. Here we show that RNA-like poly... 阅读全帖 |
|
t*******d
发帖数: 2570 | 26 Orig Life Evol Biosph. 2008 Feb;38(1):57-74. Epub 2007 Nov 16.
Lipid-assisted synthesis of RNA-like polymers from mononucleotides.
Rajamani S, Vlassov A, Benner S, Coombs A, Olasagasti F, Deamer D.
Source
Department of Chemistry and Biochemistry, University of California, Santa
Cruz, CA 95064, USA.
Abstract
A fundamental problem in research on the origin of life is the process by
which polymers capable of catalysis and replication were produced on the
early Earth. Here we show that RNA-like poly... 阅读全帖 |
|
O**********0
发帖数: 61 | 27 ☆─────────────────────────────────────☆
BHistory (往者的影子) 于 (Fri Sep 9 15:00:23 2011, 美东) 提到:
本帖是热运动组装第一个蛋白质的副贴。原帖：http://www.mitbbs.com/article_t1/TrustInJesus/676133_0_1.html
因为靠热运动组装第一个蛋白质是困难的，所以有观点认为第一个蛋白质是根据某个自
然产生的遗传基因密码(DNA/RNA)组装出来的。这便是热运动组装第一个遗传密码/基因
的理论。
在俺看来，这是先有蛋还是先有鸡的问题。蛋白质好比蛋，基因好比下蛋的鸡。如果自
然界糊出一个蛋很困难，那糊出一个下那个蛋的鸡就更困难。
事实上，每三个DNA碱基对决定一个氨基酸，加上基因的头码三个，尾码三个，对应一
个100个氨基酸长链的遗传密码（306个碱基对），其自然产生的困难程度和自然排列该
特定氨基酸长链的困难程度基本一样（遗传密码更难一点）。且遗传密码翻译为第一个
蛋白质还可能需要翻译和连接氨基酸的机制（类似一些细胞器的功能）。所以自然产生
第一个... 阅读全帖 |
|
n****n
发帖数: 295 | 28 直接联系她吧。她自己写的自我介绍如下：
I am a Ph. D. graduated from Ocean University of China, a highly reputable
university in China. As a Ph. D. trained in microbiology, biochemistry,
molecular biology field, my research focused on investigating one kind of
marine bacterium, Pseudomonas fluorescens, including the screening and
identification of bacterial strains, fermentation, purification and
application of enzyme, recombinant enzyme expression and study of the
enzymatic degradation of bacterial alginate obtai... 阅读全帖 |
|
t**********8
发帖数: 223 | 29 我想买一个enzymatic shearing的kit试试，用来替代sonication，因为我要chip的
complex太大，sonication效果很不好。但实验室另一个postdoc认为enzymatic
shearing会把dna切得太小，会miss掉很多东西，他认为这个方法只适合chromatin
modification。
很纠结，不知道是否值得一试。 |
|
A******y
发帖数: 2041 | 30 In my field, it takes Merck to publish a great paper to correct a mistake
some big bulls made at Harvard/MIT 15 years ago. Half of the isozymes of
the same class do not have enzymatic activity and likely just serving as
binding domains. Even few years ago, some reviewers still want enzymatic
activity from these enzymes to be measured (talking about not keeping up
with the literature). |
|
发帖数: 1 | 31 http://chuansong.me/n/1765488551032
2017年4月13日Science期刊在线发表论文标题为“Nucleic acid detection with
CRISPR-Cas13a/C2c2”的文章，引发了全球公共卫生领域的广泛关注。来自美国哈佛大
学-麻省理工学院布罗德研究所（以下简称布罗德研究所）、麻省理工学院麦戈文脑研
究所、麻省理工学院医学工程与科学研究所、哈佛大学怀斯生物启发工程研究所（Wyss
Institute for Biologically Inspired Engineering）的研究人员，将一种靶向RNA
（而不是DNA）的CRISPR相关酶（即Cas13a）改造为一种快速的、廉价的和高度灵敏的
诊断工具，能够指示最少至一个靶RNA或DNA分子的存在。这种新的工具被称为“
SHERLOCK（Specific High-sensitivity Enzymatic Reporter unLOCKing）”。这种技
术可能有朝一日被用来应对病毒性和细菌性流行病爆发、监控抗生素耐药性和检测癌症。
CRISPR-Cas13a/C2c2系统由... 阅读全帖 |
|
z*h
发帖数: 773 | 32 Surpassing Photosynthesis: High-Efficiency and Scalable CO2 Utilization
Through Artificial Photosynthesis
Plants like solar cells utilize intermittent non-point insolation to
biologically fix CO2 in the form of biomass carbohydrates. However, plant
photosynthesis has pretty low solar energy-to-chemical energy conversion
efficiencies (e.g., ~0.2-0.3%, global average) and consumes a large amount
of water (i.e., at least 500 kg of water per kg of biomass generated). Such
low energy efficiencies ... 阅读全帖 |
|
f**d
发帖数: 768 | 33 这是一本计算神经科学的优秀著作，全文拷贝这里（图和公式缺），有兴趣的同学可以
阅读
如需要，我可以分享PDF文件（－－仅供个人学习，无商业用途）
From Computer to Brain
William W. Lytton
From Computer to Brain
Foundations of Computational Neuroscience
Springer
William W. Lytton, M.D.
Associate Professor, State University of New York, Downstato, Brooklyn, NY
Visiting Associate Professor, University of Wisconsin, Madison
Visiting Associate Professor, Polytechnic University, Brooklyn, NY
Staff Neurologist., Kings County Hospital, Brooklyn, NY
In From Computer to Brain: ... 阅读全帖 |
|
k****z
发帖数: 1863 | 34 Yan, SD, Yan, S-F., Chen, X., Fu, J., Chen, M., Kuppusamy, P., Smith, M.A.,
Perry., G., Godman,G.C., Nawroth, P., Zweier, J.L., and Stern, D. Non-
enzymatically glycated tau in Alzheimer’s disease induces neuronal oxidant
stress resulting in cytokine gene expression and release of amyloid ß-
peptide. Nature Medicine, 1(7):693-699, 1995
Yan SD, Chen X, fu J, Chen M, Zhu H, Roher A, Slattery T, Nagashima M,
Morser J, Migheli A, Nawroth P, Goodmand G, Stern D, and Schmidt AM. RAGE in
Alzheimer... 阅读全帖 |
|
k****z
发帖数: 1863 | 35 他妈怎么把它生出来的？
Yan, SD, Yan, S-F., Chen, X., Fu, J., Chen, M., Kuppusamy, P., Smith, M.A.,
Perry., G., Godman,G.C., Nawroth, P., Zweier, J.L., and Stern, D. Non-
enzymatically glycated tau in Alzheimer’s disease induces neuronal oxidant
stress resulting in cytokine gene expression and release of amyloid ß-
peptide. Nature Medicine, 1(7):693-699, 1995
Yan SD, Chen X, fu J, Chen M, Zhu H, Roher A, Slattery T, Nagashima M,
Morser J, Migheli A, Nawroth P, Goodmand G, Stern D, and Schmidt AM. RAGE ... 阅读全帖 |
|
k****z
发帖数: 1863 | 36 发信人: pangduer (白飞飞), 信区: WaterWorld
标 题: Re: 傅瑾教授：已经把在哥大的学习经历说明和学位证书复印件提
发信站: BBS 未名空间站 (Mon Jul 23 14:03:45 2012, 美东)
对，这篇1997年的nature paper，列在第一位的yan shidu其实是唯一的通讯作者，列
在最后一位的本该是通讯作者的David Stern其实就是当时部门里的大牛。估计情况就
是David Stern是大老板，但是对这个project其实没啥贡献，然后是作为通讯作者的
Yan shidu是小老板，带领Fu Jin等一干人做出来的，才会有这样奇怪的authorship。
这样看来，Fu JIn实质上是真正干活的第一作者，凭这样一篇nature paper获得博士
也就没啥稀奇的了。Fu Jin是1999年拿的博士，1997年的paper正好对景。
凭什么方肘子要看学位证明人家就亮给这个傻逼看啊。他家菊花不是都拒绝出示学位证
明吗？人家Fu Jin教授把学位亮给学校看就好了，气死方教主及其教徒们！
Yan, SD, Yan, S-F., C... 阅读全帖 |
|
k****z
发帖数: 1863 | 37 Yan, SD, Yan, S-F., Chen, X., Fu, J., Chen, M., Kuppusamy, P., Smith, M.A.,
Perry., G., Godman,G.C., Nawroth, P., Zweier, J.L., and Stern, D. Non-
enzymatically glycated tau in Alzheimer’s disease induces neuronal oxidant
stress resulting in cytokine gene expression and release of amyloid ß-
peptide. Nature Medicine, 1(7):693-699, 1995
Yan SD, Chen X, fu J, Chen M, Zhu H, Roher A, Slattery T, Nagashima M,
Morser J, Migheli A, Nawroth P, Goodmand G, Stern D, and Schmidt AM. RAGE in
Alzheimer... 阅读全帖 |
|
J**X
发帖数: 2433 | 38 从福建医学院83年毕业的SD Yan去了美国（哥大？），做了postdoc，
然后在哥大的大老板手下做了小老板，
找了同是福建医学院89年毕业的Fu J做了她的tech./postdoc.
SD Yan的确做得不错，Fu J干活应该也不错，但哥大的博士学位应该是没有的。
连SD Yan都只是说自己是哥大postdoc，Fu J就敢说自己是哥大博士。
区别就在一个在美国，一个在中国。
另外一点就是SD Yan应该在福建科研界有些影响，所以Fu J的问题也可能会不了了之。
下面是一些关于prof. Yan的信息，和她们共同发的文章。
http://www.pharmtox.pharm.ku.edu/index.php?page=content:faculty
Dr. Yan received her M.D. from Fujian Medical University in 1983 and
completed Postdoctoral training at the Physicians & Surgeons College of
Columbia University in New ... 阅读全帖 |
|
d*******3
发帖数: 8598 | 39 发信人: Organoelf (King), 信区: Pharmaceutical
标 题: Re: 邀请业界前辈谈一谈生物制药公司未来20的发展吧
发信站: BBS 未名空间站 (Thu Jan 2 17:49:40 2014, 美东)
水便说说我能想到的技术层面吧。
chemical entity:
小分子药物，集中在癌症、感染、CNS、细菌/病毒等方面，还是有的可做，同时不断有
新的target出来，不断有nature prod出来，但受专利的影响（过期和剩余的chemical
space），大多都是在维持生计。在临床阶段对于试验病人的筛选，以后必将维持下去
。相应的试剂诊断盒业务，大公司为了利润和专利，倾向于自主研发或者收购这些诊断
盒，所以会有大的发展，类似invitrogen的公司。
大分子药物（theraputic toxin），应该在未来有大发展，基于专利和市场的考虑。只
是其价格、稳定性和进入人体的方式，不如小分子方便。至于personalisation，就是
根据病人自身的情况通过克隆和筛选得到最好的个人用药，我觉得需要等待技术上的突
破，降低成本和缩短筛选时间... 阅读全帖 |
|
x****6
发帖数: 4339 | 40 大分子照相相关的炸药奖加上这次的，已经发了14个了（见下表）。
之前主要是基于X衍射或者核磁共振的技术开发和应用，拍一些单分子的裸照。82，91
，02年颁给X衍射和核磁共振的技术开发，剩下11个的给了应用。
而冷冻电镜，这次算是第一个（可能是第二个），直接给了技术。用它可以看更加复杂
、分子量更大的大分子复合体。这些大个头的结构当然更有复杂也更有意思。
这个技术开启了一个新时代，细胞里重要的复合体实在太多。接下来可能拿奖的那就是
：真核细胞的细胞核通道复合体；一一公搞的剪接体（这个结构无论在生命进化和疾病
相关都非常的重要）；G蛋白偶联受体（跟N多疾病有关）等等。
彦宁的工作好像确实没有什么希望，葡萄糖转运蛋白跟上面这些不是一个量级的。
------------------------
2017: Chemistry cryoEM development
2009: Chemistry Venkatraman Ramakrishnan, Thomas A. Steitz, Ada E.
Yonath Studies of the structure and funct... 阅读全帖 |
|
h*****h
发帖数: 264 | 41 http://www.pku.edu.cn/ 头条
http://pkunews.pku.edu.cn/xwzh/2018-07/02/content_303545.htm
2018年7月1日起，北大生物动态光学成像中心主任、北京未来基因诊断高精尖创新中心
主任——谢晓亮正式全职回到母校北大任教，担任北京大学李兆基讲席教授。
谢晓亮
1998年，谢晓亮成为改革开放后哈佛大学聘任的第一位来自中国大陆的终身教授；2009
年，他成为改革开放后第一位哈佛冠名讲席教授的中国大陆学者；他是美国国家科学院
院士、美国国家医学院院士、美国艺术与科学院院士、美国物理化学和生物物理界最高
奖获得者，是获得美国生命医学大奖——阿尔伯尼生物医学奖的第一位华人。
附：谢晓亮教授为北大120周年校庆撰写的纪念文章：
梦想的启航与归程——我和北大的故事
光阴似箭，岁月如梭，历经百廿沧桑，母校北京大学今年迎来120周年华诞。
我生于北大，长于北大，熟悉这里的一草一木，一山一水。从北大幼儿园、北大附小、
北大附中到北京大学，我在北大度过了大部分的学生时光，与北大一起经历了中国的历
史变迁，建立了无法割舍的联系。每次回... 阅读全帖 |
|
|
t**x
发帖数: 20965 | 43 这是这个专家一开始对我们的态度：
Dear Mrs. Yong,
As promised I have now taken the time to have a good look at your Email.
The acylcarnitine profile with elevated levels of the 18:0, 16:0 and 18:1
species with relatively normal levels of the 14:1 species is indeed very
suggestive for CACT or CPT2-deficiency.
Our laboratory here in Amsterdam has extensive expertise in measuring the
activity of CACT and CPT2 as well as other mitochondrial beta-oxidation
enzymes and would be happy to help you with the identificatio... 阅读全帖 |
|
z*h
发帖数: 773 | 44 Q2. What powertrain and fuel will become the dominant transport means in the
future?
A number of scenarios could bridge between renewable primary energy and
transportation energy need (Fig. 1) through four powertrain systems: (i)
ICEs and/or electric hybrids that burn liquid biofuels and compressed
methane, (ii) battery electric vehicles (BEVs) that run on electricity
stored in rechargeable batteries, where electricity can be generated from
sun radiation, tide, geothermal, wind, and nuclear ener... 阅读全帖 |
|
h***z
发帖数: 2 | 45 Atom Biosciences and Pharmaceuticals Co. Ltd (ABP) is a China-US joint
venture biotech company that focuses on the development of new therapeutics
for cancer and metabolic diseases. ABP is located in the Zhenjiang High Tech
Park in Jiangsu Province, China (visit www.atombp.com for details). The
company is seeking a talented and highly motivated scientist to lead its
assay development and lead evaluation program.
The successful candidate will lead a team of scientists to develop and
validate bioc... 阅读全帖 |
|
p*******r
发帖数: 156 | 46 Postdoctoral positions available
A postdoctoral position is available in the Laboratory of Cellular and
Molecular Biology at the National Cancer Institute. A focus of current
studies is understanding the contribution of integrin adhesion complexes,
including focal adhesions and invadopodia, to the control of cancer cell
proliferation and survival. A class of proteins called the Arf GTPase-
activating proteins (Arf GAPs), which regulate the Ras-superfamily proteins
Arfs and integrin adhesions, ... 阅读全帖 |
|
h*****a
发帖数: 1295 | 47 需要的方向:biological/enzymatic upgrading of 1C organic small molecules into
larger fuel molecules.
具体的DOE solicitation是DOE SBIR 18.1 Topic 16b.
https://science.energy.gov/sbir/funding-opportunities/
我这边可以做CO2 reduction，需要合作者能帮忙把还原产物升级。
Phase I的项目。站内联系。
谢谢！ |
|
d****2
发帖数: 6250 | 48
这个HFCS加工和蔗糖加工完全两码事，前者是用enzymatic processing，比蔗糖
健康与否那要看你信啥了？ |
|
|
