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The number of childhood vaccines administered, either in a single day or
during the first 2 years of life, has no bearing on autism risk, new
research from the Centers for Disease Control and Prevention (CDC) shows.
The case-control study of more than 1000 children showed that there were no
significant differences between those who did and those who did not have an
autism spectrum disorder (ASD) in total antigens from vaccines received by
age 2 years or in the maximum number of antigens received on a single day.
In addition, increasing exposure to antibody-stimulating proteins or
polysaccharides from vaccines from the age of 3 months to 2 years was not
associated with risk of developing an ASD.
"Our study found no relationship with the number of vaccine antigens
received and overall ASD, autistic disorder, or ASD with regression," lead
author Frank DeStefano, MD, MPH, director of the Immunization Safety Office
at the CDC in Atlanta, Georgia, told Medscape Medical News.
The investigators noted in a release that although the current routine
schedule contains more childhood vaccines than were administered a couple
decades ago, "the maximum number of antigens that a child could be exposed
to by 2 years of age in 2013 is 315, compared with several thousand in the
late 1990s."
"Because different types of vaccines contain varying amounts of antigens,
this research acknowledged that merely counting the number of vaccines
received does not adequately account for how different vaccines and vaccine
combinations stimulate the immune system," they add.
The study was published online March 29 in the Journal of Pediatrics. |
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