t********9
发帖数: 536 | 1 Can anyone please help explain the difference among regulate vs. mediate vs.
modulate? Thanks. |
r***e
发帖数: 10135 | 2 管制，调停，调整？
找本莹莹字典不难理解吧
vs.
【在 t********9 的大作中提到】
: Can anyone please help explain the difference among regulate vs. mediate vs.
: modulate? Thanks.
|
t********9
发帖数: 536 | 3 your explanation is clear wrong, but thanks for your response. I would like
to know their subtle difference used in biology.
【在 r***e 的大作中提到】
: 管制，调停，调整？
: 找本莹莹字典不难理解吧
:
: vs.
|
w********h
发帖数: 12367 | 4 感觉regulate和modulate两个意思差不多，可互换，“调控”，
但我个人在使用时觉得regulate的主语可以是物，而modulate更通常的主语是人。
mediate的意思都是不一样的，“在。。。的帮助下促成”。
like
【在 t********9 的大作中提到】
: your explanation is clear wrong, but thanks for your response. I would like
: to know their subtle difference used in biology.
|
H****N
发帖数: 997 | 5 regulate, 通常指比较大幅度的控制，turn on and off a process; modulate， 在已
有的基础上做调整，幅度比较小；但regulate 和 modulate 没有明确的界限。
mediate则不同，是指协调两个或几个相关的processes。 |
M*P
发帖数: 6456 | 6 regulate: 你KO了基因A，基因B就不反应了，
mediate：你KO了基因A，本来B能影响C，但是现在影响不了了。但是其他因素还能影响
C
modulate：你KO了基因A，基因B本来能影响基因C，现在反应不够强不够快。
vs.
【在 t********9 的大作中提到】
: Can anyone please help explain the difference among regulate vs. mediate vs.
: modulate? Thanks.
|
t********9
发帖数: 536 | 7 Thank you guys very much for the explanation and examples. I know more
about their difference now.
【在 M*P 的大作中提到】
: regulate: 你KO了基因A，基因B就不反应了，
: mediate：你KO了基因A，本来B能影响C，但是现在影响不了了。但是其他因素还能影响
: C
: modulate：你KO了基因A，基因B本来能影响基因C，现在反应不够强不够快。
:
: vs.
|
g*****o
发帖数: 1564 | 8 let me give a try
regulate: mainly in the context of transcription regulation, eg., certain
transcription factor bind to the promoter region of a DNA sequence and
control the rate of the mRNA transcription
modulate: possibly refers to the signaling transduction that certain
signaling molecule (kinase) phosphorylate an amino acid in a downstream
protein and changes its activity
mediate: maybe A -> B -> C, then B mediate the effects from A to C?
vs.
【在 t********9 的大作中提到】
: Can anyone please help explain the difference among regulate vs. mediate vs.
: modulate? Thanks.
|
