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发帖数: 63 | 1 Two opening positions of Postdoctoral Research Fellow and Research Assistant
are available in Dr. Ke Yuan’s Lab in the Department of Pediatrics at
Boston Children’s Hospital/Harvard Medical School(www.yuankelab.com). Both
positions utilize cutting-edge interdisciplinary research and aim to
understand abnormal vascular remodeling in pulmonary arterial hypertension (
PAH) and other pulmonary vascular diseases. The Ke lab will dissect the
critical role of pericytes during pulmonary vessel remodeling, by using a
combination of cell-based models of angiogenesis (AJP 2014 PMID: 25447046),
multiple novel inducible transgenic murine models (Circulation 2018 PMID:
30586764, Cir Res 2012 PMID: 23011394), genome sequencing analysis (AJRCCM
2014 PMID: 24702692, AJP 2016 PMID: 27456128), in addition to CRISPR gene
editing toolkits, 3D spheroid models, precision-cut lung slicing technology,
high-resolution deep tissue imaging and single-cell RNA-seq. Our ultimate
goal is to identify potential therapeutic targets that could be exploited
for the development of new drugs capable of preventing abnormal vessel
remodeling and obliteration in PAH.
Boston Children's Hospital is ranked the #1 pediatric hospital in the nation
by U.S. News and World Report. It is home to the world's largest pediatric
research enterprise, the leading recipient of pediatric research funding
from the National Institutes of Health, and the primary pediatric teaching
hospital for Harvard Medical School.
Who are we looking for:
Postdoctoral Research Fellow: Highly motivated Ph.D. with a strong
background in one or more of the following areas Cell/Molecular/
Developmental Biology, Vascular Biology, Immunology, Rodent(mouse/rat)
Genetics, and related biomedical science fields are encouraged to apply. The
candidate must also have enthusiasm, excellent critical thinking skills, a
track-record of productivity as demonstrated by at least one first-author
peer-reviewed publication, an ability to work well both independently and as
part of a team, and proficiency in written and oral English communication.
Prior experience with right ventricular pressure measurements in rodents,
confocal, primary cell culture, bioinformatics (Single-cell sequencing, ChIP
-seq) and data analysis, and CRISPR mediated genome editing would be an
advantage.
Research Assistant: Candidates with Bachelor's or Master's degree in
Biomedical Sciences or related discipline, Animal handling are preferred;
good attention to details, excellent verbal and written communication skills
are prerequisite; experience with rodents, confocal, molecular/cell biology
, bioinformatics would be an advantage.
What will we offer you:
A successful candidate will have the opportunity to lead independent and
cutting-edge research projects with a world-class research facility while
obtaining valuable experience with the relevant technology that prepares
well for future positions in academia or industry. We will also provide a
customizable curriculum, individual career development/support, and
Interdisciplinary and collaborative research community.
To apply, please send 1)a cover letter with a brief statement of research
experience and future proposed interests, 2)a detailed curriculum vitae to:
Ke Yuan, PhD FAHA
Assistant Professor
Department of Pediatrics
Boston Children’s Hospital
300 Longwood Ave
t: 1-617-355-0622
email: [email protected] |
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