f*****h
发帖数: 228 | 1 http://www.cell.com/cell-systems/editorial-board
已经和超级大牛并列了,还是featured member of editorial board | b****r
发帖数: 17995 | 2 算文章数量估计真要排最前面
【在 f*****h 的大作中提到】
: http://www.cell.com/cell-systems/editorial-board
: 已经和超级大牛并列了,还是featured member of editorial board
| T*G
发帖数: 600 | 3 就是生物里的富士康，华大的文章大多是吸引眼球的，因为其他地方没他们的资源，或
者人力去做，没法很fair的在现阶段评价华大文章的reliablility, 我个人和SQ实验室
的认识的几个人，都觉得他们paper尤其单细胞测序的文章有很多问题，不可靠，
【在 f*****h 的大作中提到】
: http://www.cell.com/cell-systems/editorial-board
: 已经和超级大牛并列了,还是featured member of editorial board
| p*******i
发帖数: 449 | | w**********k
发帖数: 386 | 5 中国人号称智商天下第一，为毛总是做这种劳动密集型的东西？啥时候咱们也出一个做
个PCR就那炸药奖的家伙？
【在 T*G 的大作中提到】
: 就是生物里的富士康，华大的文章大多是吸引眼球的，因为其他地方没他们的资源，或
: 者人力去做，没法很fair的在现阶段评价华大文章的reliablility, 我个人和SQ实验室
: 的认识的几个人，都觉得他们paper尤其单细胞测序的文章有很多问题，不可靠，
| d**********t
发帖数: 20415 | 6 这行业很多常年发CNS的实验室都是有着资源或者平台优势，很多东西小实验室不是不
会做，而是没有办法做，这点都一样，没必要鄙视华大
当然单细胞测序这玩意儿靠不靠铺就不好说了
【在 T*G 的大作中提到】
: 就是生物里的富士康，华大的文章大多是吸引眼球的，因为其他地方没他们的资源，或
: 者人力去做，没法很fair的在现阶段评价华大文章的reliablility, 我个人和SQ实验室
: 的认识的几个人，都觉得他们paper尤其单细胞测序的文章有很多问题，不可靠，
| f*****h
发帖数: 228 | 7 才知道Zeming Zhang也全职回国了.
【在 f*****h 的大作中提到】
: http://www.cell.com/cell-systems/editorial-board
: 已经和超级大牛并列了,还是featured member of editorial board
| r*****m
发帖数: 3619 | 8 单细胞测序哪里不靠谱？不但是华大，其他国家的测序中心也发表了类似的结论。靶向
治疗的核心是什么？是寻找 driver mutation, 已有的靶向药杀掉敏感癌细胞之后，根
本不会再找到有规律的 driver mutation，如果有的话，早就被找到发表了，不要测序
技术，拿常规遗传学方法也找到了。测序技术只是最后敲响了这个学科的丧钟。
最要命的是根本法预测下一个 driver mutation, 不同的癌细胞有上千个 driver
mutation, 转移到脑子的和转移到肝的癌细胞有不同的 driver mutation
【在 d**********t 的大作中提到】
: 这行业很多常年发CNS的实验室都是有着资源或者平台优势，很多东西小实验室不是不
: 会做，而是没有办法做，这点都一样，没必要鄙视华大
: 当然单细胞测序这玩意儿靠不靠铺就不好说了
| b******y
发帖数: 627 | | f*****h
发帖数: 228 | 10 cell systems,马上要推出的cell子刊
【在 b******y 的大作中提到】
: What journal is this?
| | | w***r
发帖数: 709 | 11 贴个文章过来,听着有些不靠谱
【在 r*****m 的大作中提到】
: 单细胞测序哪里不靠谱？不但是华大，其他国家的测序中心也发表了类似的结论。靶向
: 治疗的核心是什么？是寻找 driver mutation, 已有的靶向药杀掉敏感癌细胞之后，根
: 本不会再找到有规律的 driver mutation，如果有的话，早就被找到发表了，不要测序
: 技术，拿常规遗传学方法也找到了。测序技术只是最后敲响了这个学科的丧钟。
: 最要命的是根本法预测下一个 driver mutation, 不同的癌细胞有上千个 driver
: mutation, 转移到脑子的和转移到肝的癌细胞有不同的 driver mutation
| N******n
发帖数: 3003 | 12 他胡说八道，肯定是做实验的。
我们这边寻找driver mutation,天天研究这些数据。
看到somatic mutation happening everywhere,所以才有点研究。
【在 w***r 的大作中提到】
: 贴个文章过来,听着有些不靠谱
| l***y
发帖数: 638 | 13 不是做这个的，能不能给简单说说driver mutation是怎么找的？
【在 N******n 的大作中提到】
: 他胡说八道，肯定是做实验的。
: 我们这边寻找driver mutation,天天研究这些数据。
: 看到somatic mutation happening everywhere,所以才有点研究。
| r*****m
发帖数: 3619 | 14 http://www.sciencemag.org/content/347/6217/78.abstract
这个文章宣判了你的死刑，就是讲，你脑门当中挨了一枪
【在 N******n 的大作中提到】
: 他胡说八道，肯定是做实验的。
: 我们这边寻找driver mutation,天天研究这些数据。
: 看到somatic mutation happening everywhere,所以才有点研究。
| N******n
发帖数: 3003 | 15 这个我们都知道，要是那么容易，我们不失业了吗？
【在 r*****m 的大作中提到】
: http://www.sciencemag.org/content/347/6217/78.abstract
: 这个文章宣判了你的死刑，就是讲，你脑门当中挨了一枪
| w***r
发帖数: 709 | 16 这篇文章和你说的有个p关系,拿真货来！！
【在 r*****m 的大作中提到】
: http://www.sciencemag.org/content/347/6217/78.abstract
: 这个文章宣判了你的死刑，就是讲，你脑门当中挨了一枪
| w***r
发帖数: 709 | | r*****m
发帖数: 3619 | 18 Results: 46
Select item 25597018
1.
Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated
Genes in Seminomas.
Cutcutache I, Suzuki Y, Tan IB, Ramgopal S, Zhang S, Ramnarayanan K, Gan A,
Lee HH, Tay ST, Ooi A, Ong CK, Bolthouse JT, Lane BR, Anema JG, Kahnoski RJ,
Tan P, Teh BT, Rozen SG.
Eur Urol. 2015 Jan 14. pii: S0302-2838(14)01396-7. doi: 10.1016/j.eururo.
2014.12.040. [Epub ahead of print]
PMID: 25597018 [PubMed - as supplied by publisher] Free Article
Related citations
Select item 25572314
2.
Patient-specific driver gene prediction and risk assessment through
integrated network analysis of cancer omics profiles.
Bertrand D, Chng KR, Sherbaf FG, Kiesel A, Chia BK, Sia YY, Huang SK, Hoon
DS, Liu ET, Hillmer A, Nagarajan N.
Nucleic Acids Res. 2015 Jan 8. pii: gku1393. [Epub ahead of print]
PMID: 25572314 [PubMed - as supplied by publisher] Free Article
Related citations
Select item 25363767
3.
The mutational landscapes of genetic and chemical models of Kras-driven lung
cancer.
Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, Delrosario R,
Jen KY, Gurley KE, Kemp CJ, Fredlund E, Quigley DA, Adams DJ, Balmain A.
Nature. 2015 Jan 22;517(7535):489-92. doi: 10.1038/nature13898. Epub 2014
Nov 2.
PMID: 25363767 [PubMed - indexed for MEDLINE]
Related citations
Select item 25252913
4.
A recurrent activating PLCG1 mutation in cardiac angiosarcomas increases
apoptosis resistance and invasiveness of endothelial cells.
Kunze K, Spieker T, Gamerdinger U, Nau K, Berger J, Dreyer T, Sindermann JR,
Hoffmeier A, Gattenlöhner S, Bräuninger A.
Cancer Res. 2014 Nov 1;74(21):6173-83. doi: 10.1158/0008-5472.CAN-14-1162.
Epub 2014 Sep 24.
PMID: 25252913 [PubMed - indexed for MEDLINE]
Related citations
Select item 25188507
5.
Platform comparison for evaluation of ALK protein immunohistochemical
expression, genomic copy number and hotspot mutation status in
neuroblastomas.
Yan B, Kuick CH, Lim M, Venkataraman K, Tennakoon C, Loh E, Lian D, Leong MY
, Lakshmanan M, Tergaonkar V, Sung WK, Soh SY, Chang KT.
PLoS One. 2014 Sep 4;9(9):e106575. doi: 10.1371/journal.pone.0106575.
eCollection 2014.
PMID: 25188507 [PubMed - in process] Free PMC Article
Related citations
Select item 24913807
6.
Multidriver mutation analysis in pulmonary mucinous adenocarcinoma in Taiwan
Gow CH, Wu SG, Chang YL, Shih JY.
Med Oncol. 2014 Jul;31(7):34. doi: 10.1007/s12032-014-0034-4. Epub 2014 Jun
10.
PMID: 24913807 [PubMed - in process]
Related citations
Select item 24897505
7.
Evolutionary trajectories of hyperdiploid ALL in monozygotic twins.
Bateman CM, Alpar D, Ford AM, Colman SM, Wren D, Morgan M, Kearney L,
Greaves M.
Leukemia. 2015 Jan;29(1):58-65. doi: 10.1038/leu.2014.177. Epub 2014 Jun 4.
PMID: 24897505 [PubMed - in process]
Related citations
Select item 24778153
8.
Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.
Wang L, Shalek AK, Lawrence M, Ding R, Gaublomme JT, Pochet N, Stojanov P,
Sougnez C, Shukla SA, Stevenson KE, Zhang W, Wong J, Sievers QL, MacDonald
BT, Vartanov AR, Goldstein NR, Neuberg D, He X, Lander E, Hacohen N, Regev A
, Getz G, Brown JR, Park H, Wu CJ.
Blood. 2014 Aug 14;124(7):1089-98. doi: 10.1182/blood-2014-01-552067. Epub
2014 Apr 28.
PMID: 24778153 [PubMed - in process]
Related citations
Select item 24747642
9.
Integrated genomic characterization of adrenocortical carcinoma.
Assié G, Letouzé E, Fassnacht M, Jouinot A, Luscap W, Barreau O, Omeiri H,
Rodriguez S, Perlemoine K, René-Corail F, Elarouci N, Sbiera S, Kroiss M,
Allolio B, Waldmann J, Quinkler M, Mannelli M, Mantero F, Papathomas T, De
Krijger R, Tabarin A, Kerlan V, Baudin E, Tissier F, Dousset B, Groussin L,
Amar L, Clauser E, Bertagna X, Ragazzon B, Beuschlein F, Libé R, de Reyniè
s A, Bertherat J.
Nat Genet. 2014 Jun;46(6):607-12. doi: 10.1038/ng.2953. Epub 2014 Apr 20.
PMID: 24747642 [PubMed - indexed for MEDLINE]
Related citations
Select item 24699064
10.
Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by
single-cell sequencing.
Yu C, Yu J, Yao X, Wu WK, Lu Y, Tang S, Li X, Bao L, Li X, Hou Y, Wu R, Jian
M, Chen R, Zhang F, Xu L, Fan F, He J, Liang Q, Wang H, Hu X, He M, Zhang X
, Zheng H, Li Q, Wu H, Chen Y, Yang X, Zhu S, Xu X, Yang H, Wang J, Zhang X,
Sung JJ, Li Y, Wang J.
Cell Res. 2014 Jun;24(6):701-12. doi: 10.1038/cr.2014.43. Epub 2014 Apr 4.
PMID: 24699064 [PubMed - indexed for MEDLINE]
Related citations
Select item 24584070
11.
A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T
cell lymphoma.
Yoo HY, Sung MK, Lee SH, Kim S, Lee H, Park S, Kim SC, Lee B, Rho K, Lee JE,
Cho KH, Kim W, Ju H, Kim J, Kim SJ, Kim WS, Lee S, Ko YH.
Nat Genet. 2014 Apr;46(4):371-5. doi: 10.1038/ng.2916. Epub 2014 Mar 2.
PMID: 24584070 [PubMed - indexed for MEDLINE]
Related citations
Select item 24487277
12.
Genomic architecture and evolution of clear cell renal cell carcinomas
defined by multiregion sequencing.
Gerlinger M, Horswell S, Larkin J, Rowan AJ, Salm MP, Varela I, Fisher R,
McGranahan N, Matthews N, Santos CR, Martinez P, Phillimore B, Begum S,
Rabinowitz A, Spencer-Dene B, Gulati S, Bates PA, Stamp G, Pickering L, Gore
M, Nicol DL, Hazell S, Futreal PA, Stewart A, Swanton C.
Nat Genet. 2014 Mar;46(3):225-33. doi: 10.1038/ng.2891. Epub 2014 Feb 2.
PMID: 24487277 [PubMed - indexed for MEDLINE]
Related citations
Select item 24413735
13.
RAG-mediated recombination is the predominant driver of oncogenic
rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
Papaemmanuil E, Rapado I, Li Y, Potter NE, Wedge DC, Tubio J, Alexandrov LB,
Van Loo P, Cooke SL, Marshall J, Martincorena I, Hinton J, Gundem G, van
Delft FW, Nik-Zainal S, Jones DR, Ramakrishna M, Titley I, Stebbings L,
Leroy C, Menzies A, Gamble J, Robinson B, Mudie L, Raine K, O'Meara S,
Teague JW, Butler AP, Cazzaniga G, Biondi A, Zuna J, Kempski H, Muschen M,
Ford AM, Stratton MR, Greaves M, Campbell PJ.
Nat Genet. 2014 Feb;46(2):116-25. doi: 10.1038/ng.2874. Epub 2014 Jan 12.
PMID: 24413735 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 24373969
14.
FuseFISH: robust detection of transcribed gene fusions in single cells.
Semrau S, Crosetto N, Bienko M, Boni M, Bernasconi P, Chiarle R, van
Oudenaarden A.
Cell Rep. 2014 Jan 16;6(1):18-23. doi: 10.1016/j.celrep.2013.12.002. Epub
2013 Dec 27.
PMID: 24373969 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 24367274
15.
Comprehensive analysis of transcriptome variation uncovers known and novel
driver events in T-cell acute lymphoblastic leukemia.
Atak ZK, Gianfelici V, Hulselmans G, De Keersmaecker K, Devasia AG, Geerdens
E, Mentens N, Chiaretti S, Durinck K, Uyttebroeck A, Vandenberghe P,
Wlodarska I, Cloos J, Foà R, Speleman F, Cools J, Aerts S.
PLoS Genet. 2013;9(12):e1003997. doi: 10.1371/journal.pgen.1003997. Epub
2013 Dec 19.
PMID: 24367274 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 24362818
16.
Integrated genomic analysis identifies recurrent mutations and evolution
patterns driving the initiation and progression of follicular lymphoma.
Okosun J, Bödör C, Wang J, Araf S, Yang CY, Pan C, Boller S,
Cittaro D, Bozek M, Iqbal S, Matthews J, Wrench D, Marzec J, Tawana K, Popov
N, O'Riain C, O'Shea D, Carlotti E, Davies A, Lawrie CH, Matolcsy A,
Calaminici M, Norton A, Byers RJ, Mein C, Stupka E, Lister TA, Lenz G,
Montoto S, Gribben JG, Fan Y, Grosschedl R, Chelala C, Fitzgibbon J.
Nat Genet. 2014 Feb;46(2):176-81. doi: 10.1038/ng.2856. Epub 2013 Dec 22.
PMID: 24362818 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 24297535
17.
Integrative analysis of two cell lines derived from a non-small-lung cancer
patient--a panomics approach.
Mayba O, Gnad F, Peyton M, Zhang F, Walter K, Du P, Huntley MA, Jiang Z, Liu
J, Haverty PM, Gentleman RC, Li R, Minna JD, Li Y, Shames DS, Zhang Z.
Pac Symp Biocomput. 2014:75-86.
PMID: 24297535 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 24123875
18.
Somatic point mutations occurring early in development: a monozygotic twin
study.
Li R, Montpetit A, Rousseau M, Wu SY, Greenwood CM, Spector TD, Pollak M,
Polychronakos C, Richards JB.
J Med Genet. 2014 Jan;51(1):28-34. doi: 10.1136/jmedgenet-2013-101712. Epub
2013 Oct 11.
PMID: 24123875 [PubMed - indexed for MEDLINE]
Related citations
Select item 23799614
19.
Whole-exome sequencing to identify novel somatic mutations in squamous cell
lung cancers.
Zheng CX, Gu ZH, Han B, Zhang RX, Pan CM, Xiang Y, Rong XJ, Chen X, Li QY,
Wan HY.
Int J Oncol. 2013 Sep;43(3):755-64. doi: 10.3892/ijo.2013.1991. Epub 2013
Jun 25.
PMID: 23799614 [PubMed - indexed for MEDLINE]
Related citations
Select item 23733339
20.
Exome sequencing identifies putative drivers of progression of transient
myeloproliferative disorder to AMKL in infants with Down syndrome.
Nikolaev SI, Santoni F, Vannier A, Falconnet E, Giarin E, Basso G, Hoischen
A, Veltman JA, Groet J, Nizetic D, Antonarakis SE.
Blood. 2013 Jul 25;122(4):554-61. doi: 10.1182/blood-2013-03-491936. Epub
2013 Jun 3.
PMID: 23733339 [PubMed - indexed for MEDLINE] Free Article
Related citations
Select item 23704925
21.
Comprehensive genomic characterization of cutaneous malignant melanoma cell
lines derived from metastatic lesions by whole-exome sequencing and SNP
array profiling.
Cifola I, Pietrelli A, Consolandi C, Severgnini M, Mangano E, Russo V, De
Bellis G, Battaglia C.
PLoS One. 2013 May 21;8(5):e63597. doi: 10.1371/journal.pone.0063597. Print
2013.
PMID: 23704925 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 23620403
22.
Clonal evolution, genomic drivers, and effects of therapy in chronic
lymphocytic leukemia.
Ouillette P, Saiya-Cork K, Seymour E, Li C, Shedden K, Malek SN.
Clin Cancer Res. 2013 Jun 1;19(11):2893-904. doi: 10.1158/1078-0432.CCR-13-
0138. Epub 2013 Apr 25.
PMID: 23620403 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 23593033
23.
Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel
driver of hepatocarcinogenesis.
Riordan JD, Keng VW, Tschida BR, Scheetz TE, Bell JB, Podetz-Pedersen KM,
Moser CD, Copeland NG, Jenkins NA, Roberts LR, Largaespada DA, Dupuy AJ.
PLoS Genet. 2013 Apr;9(4):e1003441. doi: 10.1371/journal.pgen.1003441. Epub
2013 Apr 4.
PMID: 23593033 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 23588493
24.
Identification of tumorigenic and therapeutically actionable mutations in
transplantable mouse tumor cells by exome sequencing.
Bhadury J, López MD, Muralidharan SV, Nilsson LM, Nilsson JA.
Oncogenesis. 2013 Apr 15;2:e44. doi: 10.1038/oncsis.2013.8.
PMID: 23588493 [PubMed] Free PMC Article
Related citations
Select item 23471846
25.
Complex tumor genomes inferred from single circulating tumor cells by array-
CGH and next-generation sequencing.
Heitzer E, Auer M, Gasch C, Pichler M, Ulz P, Hoffmann EM, Lax S,
Waldispuehl-Geigl J, Mauermann O, Lackner C, Höfler G, Eisner F, Sill H
, Samonigg H, Pantel K, Riethdorf S, Bauernhofer T, Geigl JB, Speicher MR.
Cancer Res. 2013 May 15;73(10):2965-75. doi: 10.1158/0008-5472.CAN-12-4140.
Epub 2013 Mar 7.
PMID: 23471846 [PubMed - indexed for MEDLINE] Free Article
Related citations
Select item 23450047
26.
Whole-exome sequencing studies of nonfunctioning pituitary adenomas.
Newey PJ, Nesbit MA, Rimmer AJ, Head RA, Gorvin CM, Attar M, Gregory L, Wass
JA, Buck D, Karavitaki N, Grossman AB, McVean G, Ansorge O, Thakker RV.
J Clin Endocrinol Metab. 2013 Apr;98(4):E796-800. doi: 10.1210/jc.2012-4028.
Epub 2013 Feb 28.
PMID: 23450047 [PubMed - indexed for MEDLINE]
Related citations
Select item 23340843
27.
Systematic analysis of somatic mutations in phosphorylation signaling
predicts novel cancer drivers.
Reimand J, Bader GD.
Mol Syst Biol. 2013;9:637. doi: 10.1038/msb.2012.68.
PMID: 23340843 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 23200536
28.
Molecular genetics of AML.
Link DC.
Best Pract Res Clin Haematol. 2012 Dec;25(4):409-14. doi: 10.1016/j.beha.
2012.10.002. Epub 2012 Oct 23. Review.
PMID: 23200536 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 23012583
29.
Integrated analysis of tumor samples sheds light on tumor heterogeneity.
Parisi F, Micsinai M, Strino F, Ariyan S, Narayan D, Bacchiocchi A, Cheng E,
Xu F, Li P, Kluger H, Halaban R, Kluger Y.
Yale J Biol Med. 2012 Sep;85(3):347-61. Epub 2012 Sep 25.
PMID: 23012583 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 22991232
30.
Molecular diagnostics and personalized medicine in oncology: challenges and
opportunities.
Normanno N, Rachiglio AM, Roma C, Fenizia F, Esposito C, Pasquale R, La
Porta ML, Iannaccone A, Micheli F, Santangelo M, Bergantino F, Costantini S,
De Luca A.
J Cell Biochem. 2013 Mar;114(3):514-24. doi: 10.1002/jcb.24401.
PMID: 22991232 [PubMed - indexed for MEDLINE]
Related citations
Select item 22954134
31.
Finding driver pathways in cancer: models and algorithms.
Vandin F, Upfal E, Raphael BJ.
Algorithms Mol Biol. 2012 Sep 6;7(1):23. doi: 10.1186/1748-7188-7-23.
PMID: 22954134 [PubMed] Free PMC Article
Related citations
Select item 22878650
32.
Global mutational profiling of formalin-fixed human colon cancers from a
pathology archive.
Adams MD, Veigl ML, Wang Z, Molyneux N, Sun S, Guda K, Yu X, Markowitz SD,
Willis J.
Mod Pathol. 2012 Dec;25(12):1599-608. doi: 10.1038/modpathol.2012.121. Epub
2012 Aug 10.
PMID: 22878650 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 22813853
33.
Two mechanisms underlying the loss of p16(Ink4a) function are associated
with distinct tumorigenic consequences for WS MEFs escaping from senescence.
Wu X, Jia S, Zhang X, Si X, Tang W, Luo Y.
Mech Ageing Dev. 2012 Aug;133(8):549-55. doi: 10.1016/j.mad.2012.07.002.
Epub 2012 Jul 16.
PMID: 22813853 [PubMed - indexed for MEDLINE]
Related citations
Select item 22649506
34.
Paired tumor and normal whole genome sequencing of metastatic olfactory
neuroblastoma.
Weiss GJ, Liang WS, Izatt T, Arora S, Cherni I, Raju RN, Hostetter G,
Kurdoglu A, Christoforides A, Sinari S, Baker AS, Metpally R, Tembe WD,
Phillips L, Von Hoff DD, Craig DW, Carpten JD.
PLoS One. 2012;7(5):e37029. doi: 10.1371/journal.pone.0037029. Epub 2012 May
23.
PMID: 22649506 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 22386266
35.
Opening Pandora's Box--the new biology of driver mutations and clonal
evolution in cancer as revealed by next generation sequencing.
Ma QC, Ennis CA, Aparicio S.
Curr Opin Genet Dev. 2012 Feb;22(1):3-9. doi: 10.1016/j.gde.2012.01.008.
Epub 2012 Mar 1. Review.
PMID: 22386266 [PubMed - indexed for MEDLINE]
Related citations
Select item 22385957
36.
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative
myeloproliferative neoplasm.
Hou Y, Song L, Zhu P, Zhang B, Tao Y, Xu X, Li F, Wu K, Liang J, Shao D, Wu
H, Ye X, Ye C, Wu R, Jian M, Chen Y, Xie W, Zhang R, Chen L, Liu X, Yao X,
Zheng H, Yu C, Li Q, Gong Z, Mao M, Yang X, Yang L, Li J, Wang W, Lu Z, Gu N
, Laurie G, Bolund L, Kristiansen K, Wang J, Yang H, Li Y, Zhang X, Wang J.
Cell. 2012 Mar 2;148(5):873-85. doi: 10.1016/j.cell.2012.02.028.
PMID: 22385957 [PubMed - indexed for MEDLINE] Free Article
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Select item 22258401
37.
Quantification of subclonal distributions of recurrent genomic aberrations
in paired pre-treatment and relapse samples from patients with B-cell
chronic lymphocytic leukemia.
Knight SJ, Yau C, Clifford R, Timbs AT, Sadighi Akha E, Dréau HM, Burns A,
Ciria C, Oscier DG, Pettitt AR, Dutton S, Holmes CC, Taylor J, Cazier JB,
Schuh A.
Leukemia. 2012 Jul;26(7):1564-75. doi: 10.1038/leu.2012.13. Epub 2012 Jan 19.
PMID: 22258401 [PubMed - indexed for MEDLINE] Free PMC Article
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Select item 22238327
38.
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations,
and are unlikely to exert a driver effect in childhood MDS and JMML.
Hirabayashi S, Flotho C, Moetter J, Heuser M, Hasle H, Gruhn B, Klingebiel T
, Thol F, Schlegelberger B, Baumann I, Strahm B, Stary J, Locatelli F, Zecca
M, Bergstraesser E, Dworzak M, van den Heuvel-Eibrink MM, De Moerloose B,
Ogawa S, Niemeyer CM, Wlodarski MW; European Working Group of MDS in
Childhood.
Blood. 2012 Mar 15;119(11):e96-9. doi: 10.1182/blood-2011-12-395087. Epub
2012 Jan 11.
PMID: 22238327 [PubMed - indexed for MEDLINE] Free Article
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Select item 22237626
39.
Exploiting the mutanome for tumor vaccination.
Castle JC, Kreiter S, Diekmann J, Löwer M, van de Roemer N, de Graaf J,
Selmi A, Diken M, Boegel S, Paret C, Koslowski M, Kuhn AN, Britten CM,
Huber C, Türeci O, Sahin U.
Cancer Res. 2012 Mar 1;72(5):1081-91. doi: 10.1158/0008-5472.CAN-11-3722.
Epub 2012 Jan 11.
PMID: 22237626 [PubMed - indexed for MEDLINE] Free Article
Related citations
Select item 21984974
40.
Temporal dissection of tumorigenesis in primary cancers.
Durinck S, Ho C, Wang NJ, Liao W, Jakkula LR, Collisson EA, Pons J, Chan SW,
Lam ET, Chu C, Park K, Hong SW, Hur JS, Huh N, Neuhaus IM, Yu SS, Grekin RC
, Mauro TM, Cleaver JE, Kwok PY, LeBoit PE, Getz G, Cibulskis K, Aster JC,
Huang H, Purdom E, Li J, Bolund L, Arron ST, Gray JW, Spellman PT, Cho RJ.
Cancer Discov. 2011 Jul;1(2):137-43. doi: 10.1158/2159-8290.CD-11-0028. Epub
2011 Jun 29.
PMID: 21984974 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations
Select item 20975737
41.
Trastuzumab and beyond: sequencing cancer genomes and predicting molecular
networks.
Roukos DH.
Pharmacogenomics J. 2011 Apr;11(2):81-92. doi: 10.1038/tpj.2010.81. Epub
2010 Oct 26. Review.
PMID: 20975737 [PubMed - indexed for MEDLINE]
Related citations
Select item 20725993
42.
Broad copy neutral-loss of heterozygosity regions and rare recurring copy
number abnormalities in normal karyotype-acute myeloid leukemia genomes.
Barresi V, Romano A, Musso N, Capizzi C, Consoli C, Martelli MP, Palumbo G,
Di Raimondo F, Condorelli DF.
Genes Chromosomes Cancer. 2010 Nov;49(11):1014-23. doi: 10.1002/gcc.20810.
PMID: 20725993 [PubMed - indexed for MEDLINE]
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Select item 20014921
43.
Novel clinico-genome network modeling for revolutionizing genotype-phenotype
-based personalized cancer care.
Roukos DH.
Expert Rev Mol Diagn. 2010 Jan;10(1):33-48. doi: 10.1586/erm.09.69. Review.
PMID: 20014921 [PubMed - indexed for MEDLINE]
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Select item 19654296
44.
Cancer-specific high-throughput annotation of somatic mutations:
computational prediction of driver missense mutations.
Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW,
Vogelstein B, Karchin R.
Cancer Res. 2009 Aug 15;69(16):6660-7. doi: 10.1158/0008-5472.CAN-09-1133.
Epub 2009 Aug 4.
PMID: 19654296 [PubMed - indexed for MEDLINE] Free PMC Article
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Select item 19516027
45.
Mutation of FOXL2 in granulosa-cell tumors of the ovary.
Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G,
Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R
, Swenerton KD, Miller D, Clement PB, Crane C, Madore J, Provencher D, Leung
P, DeFazio A, Khattra J, Turashvili G, Zhao Y, Zeng T, Glover JN,
Vanderhyden B, Zhao C, Parkinson CA, Jimenez-Linan M, Bowtell DD, Mes-Masson
AM, Brenton JD, Aparicio SA, Boyd N, Hirst M, Gilks CB, Marra M, Huntsman
DG.
N Engl J Med. 2009 Jun 25;360(26):2719-29. doi: 10.1056/NEJMoa0902542. Epub
2009 Jun 10.
PMID: 19516027 [PubMed - indexed for MEDLINE] Free Article
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Select item 18252861
46.
High-throughput sequence analysis of the tyrosine kinome in acute myeloid
leukemia.
Loriaux MM, Levine RL, Tyner JW, Fröhling S, Scholl C, Stoffregen EP,
Wernig G, Erickson H, Eide CA, Berger R, Bernard OA, Griffin JD, Stone RM,
Lee B, Meyerson M, Heinrich MC, Deininger MW, Gilliland DG, Druker BJ.
Blood. 2008 May 1;111(9):4788-96. doi: 10.1182/blood-2007-07-101394. Epub
2008 Feb 5.
PMID: 18252861 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations | r*****m
发帖数: 3619 | 19 跟着米犹吸毒抽风，不晓得自己拿出文章来证明下一个driver mutation 是什么，叫嚣
着让别人证明。
下一个driver mutation 是哪个？说啊？讲啊？上面这些文章只讲了一件事，那就是没
有下一个 driver mutation | n******7
发帖数: 12463 | 20 这个能给个reference吗？
前段时间听一个报告是说不同的tissue直接的转移是有pattern的
但是没听说过你说的这个
【在 r*****m 的大作中提到】
: 跟着米犹吸毒抽风，不晓得自己拿出文章来证明下一个driver mutation 是什么，叫嚣
: 着让别人证明。
: 下一个driver mutation 是哪个？说啊？讲啊？上面这些文章只讲了一件事，那就是没
: 有下一个 driver mutation
| w***r
发帖数: 709 | 21 一会给你一千个文章让你找
【在 n******7 的大作中提到】
: 这个能给个reference吗？
: 前段时间听一个报告是说不同的tissue直接的转移是有pattern的
: 但是没听说过你说的这个
| n******7
发帖数: 12463 | 22 我发现了。。
那个列表开始我还仔细扫了扫，完全不沾边吗
【在 w***r 的大作中提到】
: 一会给你一千个文章让你找
|
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