g******5
发帖数: 34 | 1 因为自己没什么array的数据，想从oncomine里找点东西。注册了帐号但不知道从哪里
下手。网上的tutorial挺少的。
我想分析某个通路在不同的breast cancer里的差异表达。比如在化疗后通路抑制。或
者通路高就化疗抗性。
望大牛指点迷津。 |
K**4
发帖数: 1015 | 2 向作芯片分析
还是从头学R，bioconductor吧，那上面的解决不了你的问题
【在 g******5 的大作中提到】
: 因为自己没什么array的数据，想从oncomine里找点东西。注册了帐号但不知道从哪里
: 下手。网上的tutorial挺少的。
: 我想分析某个通路在不同的breast cancer里的差异表达。比如在化疗后通路抑制。或
: 者通路高就化疗抗性。
: 望大牛指点迷津。
|
g******5
发帖数: 34 | 3 谢谢。也在下班后自学R。现在是已有低通量的实验数据。想从oncomine里找些支持性
的东西。高年级了，等不到自己sample的array结果了。 |
l**********1
发帖数: 5204 | 4 RE LZ
pls refer
Oncomine data analysis
The relative expression of individual PR target genes in
human breast tumor samples was determined by searching
the Oncomine database (version 4.4, October 2011 data
release, [36]). Individual PR target genes (for example,
RGS2) were queried in The Cancer Genome Atlas
(TCGA) Breast 2 dataset. Oncomine output data was
sorted to isolate ‘cancer versus normal’ associations and
reported (Figure 2A) as the copy number unit expression
values for blood, normal breast and breast carcinoma samples
using box-and-whiskers plots (dots: maximum/minimum,
whiskers: 90/10 percentiles, box: 75/25 percentiles,
line: median of all samples). For each analysis, specific
breast carcinomas specified for each gene
below ignored
cited from
Knutson TP et al. (2012.)
Phosphorylated and sumoylation-deficient progesterone receptors drive
proliferative gene signatures during breast cancer progression.
Breast Cancer Res. 14: R95.
HTTP: //www.ncbi.nlm.nih.gov/pubmed/22697792
【在 g******5 的大作中提到】
: 谢谢。也在下班后自学R。现在是已有低通量的实验数据。想从oncomine里找些支持性
: 的东西。高年级了，等不到自己sample的array结果了。
|
g******5
发帖数: 34 | 5 Thank you a lot. Got the reply from the ID I worship. Will try as soon as
possible. |
g******5
发帖数: 34 | 6 are you a computer program specifically written for bio-related questions or
a real person? |
g******5
发帖数: 34 | 7 I am now reading the . Thank you. |
l**********1
发帖数: 5204 | 8 De rien.
【在 g******5 的大作中提到】
: I am now reading the . Thank you.
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