s****l
发帖数: 10462 | 1 IPO Market Unlocking for 'Omics-related Companies, but It's 'Anything but
Robust'
December 30, 2010
Type size:
-
+EmailPrinter-friendly versionRSS FeedBy Tony Fong
NEW YORK (GenomeWeb News) – For most of 2010, the IPO market froze out the
life science tools and 'omics market, but by the end of the summer, there
were signs that the public markets may be slowly welcoming firms operating
in the space, as a handful of public offerings ended a cold snap.
The IPO market for 'omics firms has been a gri... 阅读全帖 |
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p**********1
发帖数: 1458 | 2 I don't quite understand his argument.
This is because for community
card sequences c1 and c2, the probability c1 is the first sequence and c2 is
the second sequence is the same as the probability that c2 is the first
sequence and c1 is the second sequence.
how about the case where sequence c1=c2? for instance, P1 has AA, P2 has KK,
flop A72r. with replacement, we can have c1=c2={K K}, without replacement,
we cannot. furthermore, without replacement, if c1={K X}, then c2=/={K K}
with probability... 阅读全帖 |
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A*******g
发帖数: 607 | 3 PWM 1khz 只是专利的第一项：
http://www.freepatentsonline.com/y2011/0164069.html
What is claimed is:
1. An electronic device, comprising: a display panel comprising a plurality
of pixels; a light source comprising a plurality of light emitting diode (
LED) strings adapted to generate light to illuminate the plurality of pixels
; and display control logic adapted to sequentially activate and deactivate
each LED string of the plurality of LED strings at a frequency of
approximately at least 1 kHz.
2. The el... 阅读全帖 |
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A*******g
发帖数: 607 | 4 PWM 1khz 只是专利的第一项：
http://www.freepatentsonline.com/y2011/0164069.html
What is claimed is:
1. An electronic device, comprising: a display panel comprising a plurality
of pixels; a light source comprising a plurality of light emitting diode (
LED) strings adapted to generate light to illuminate the plurality of pixels
; and display control logic adapted to sequentially activate and deactivate
each LED string of the plurality of LED strings at a frequency of
approximately at least 1 kHz.
2. The el... 阅读全帖 |
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p*****r
发帖数: 2 | 5 那我就不提TCP了，就说sequence巴：
I'm calculating the QoS-delay variation(jitter):
I think for a transport Protocol for Real-Time Applications, like
audio/video, the sequence of data should be considered when
you calculate jitter. for example:
sender sends data out with sequence 0, 1, ...9.
Receiver A may receive the data with sequence 0,1,...9 while
Receiver B may receive the data with sequence 1,...9, 0.
Suppose the arrival interval time of the data is the same,
then, without considering the sequence, th |
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m*c
发帖数: 74 | 6 【 以下文字转载自 JobHunting 讨论区 】
【 原文由 mac 所发表 】
The program should monitor a possibly infinite stream of characters
from the keyboard (standard input). If it detects the sequence "aaa" it
outputs a "0". If it detects the sequence "aba" it outputs a "1".
DO NOT detect sequences within sequences. The program should exit
cleanly when it detects an End Of Input. For example:
The following sequence aababaaabaaa would produce the
following result: 100
While the following sequence aaaba |
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z***h
发帖数: 998 | 7 draft sequence is easier and cheaper to get than the finished sequence, it
has lower sequence coverage and contains lots of unclosed gaps.
Basically, if you already get a organism's finished sequences, to sequence its
related species might only need to be draft oriented. For example,
C.elegans vs. C.briggsae. Thus, draft sequences is widely used in comparative
genomics. |
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l****u
发帖数: 46 | 8 http://www.ncbi.nlm.nih.gov/sra
Sequence Read Archive (SRA) and Trace Archive repositories have been
discontinued
Due to budget constraints, NCBI will be discontinuing its Sequence Read
Archive (SRA) and Trace Archive repositories for high-throughput sequence
data. Closure of the databases will occur in phases. SRA and Trace will stop
accepting some types of submissions in the coming weeks, and all
submissions within the next 12 months. Over the next several months, NCBI
will be working with sta... 阅读全帖 |
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j*****d
发帖数: 787 | 9 http://the-scientist.com/2011/09/20/plant-rnas-found-in-mammals
+Plant RNAs Found in Mammals
MicroRNAs from plants accumulate in mammalian blood and tissues, where they
can regulate gene expression.
By Cristina Luiggi | September 20, 2011
11 Comments Link thisStumbleTweet thisDreamstime.com, Rewat
WannasukMicroRNAs from common plant crops such as rice and cabbage can be
found in the blood and tissues of humans and other plant-eating mammals,
according to a study published today in Cell Research.... 阅读全帖 |
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h**********r
发帖数: 671 | 10 必须是pESC系列。
当时我还问大家要不要加kozak序列，也没说出个所以然来。后来我终于等到了客服的
答复。下面就是：
The GAL1 and GAL10 yeast promoters from the pESC-Leu vector have the FLAG or
the MYC epitopes in the two MCS of the vector. Both include ATG codons at
the 5’ end of the FLAG and the MYC epitopes. If you clone into the Bgl II
or the Xho I site in frame with the ATG of the epitope tag, you will have
the start codon, kozak sequence and should get good expression of your N-
tagged protein. If you need the epitope tag at the C-terminal, ... 阅读全帖 |
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m******p
发帖数: 67 | 11 I have genomic DNA samples of about 1000 diabetic patients. We are
interested in examining the sequence variations of a gene in these samples.
But we are not good at this and have 2 questions.
1) Can we do that by traditional Sanger sequencing? This is very doable.
We first PCR the fragment of interest, and then do sequencing. But the
problem is that Sanger sequencing cannot distinguish paternal and maternal
alleles, that is, we cannot tell whether a variation is homozygous or
heterozygous, u... 阅读全帖 |
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n******7
发帖数: 12463 | 13 你自己看最近的publication。pacbio的东西多年没关注了，这个nano pore应该是他们
最直接的竞争者。
http://biorxiv.org/content/early/2015/01/06/013490
We describe software developed to make use of these data as existing
packages were incapable of assembling long reads at such high error rate (~
35% error).
Some runs have produced upwards of 490 Mb of sequencing data per flow cell
over a 48 hour period. All together, we generated a total of 120x coverage
of the genome with an average read length of 5473bp but with a long tail
extendin... 阅读全帖 |
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c**********n
发帖数: 177 | 15 德国组那个trial里面有13个病人，8个像你说的切了以后没有relapse，但是5个是切了
以后有relapse而且relapse越来越频繁。而且文中提到standard treatment已经对这五
人无效了。至于什么是standard treatment我自己脑补是chemo，checkpoint试了吧，
不然也不会上这个clinical trial。clinical trial风险还是挺大的，可以参看下2013
年关于MAGE A3的Car T clinical trial。参与实验的直接死于Car T off target引起
的cardiovascular failure。
http://stm.sciencemag.org/content/5/197/197ra103.short
至于classII还是classI response谁占主导，我觉得比较难说。文章里是哪个实验得出
CD4 还是CD8 占主要response我没看到（读的不够仔细）。不过可以肯定的是，没有
CD8绝对不行，参看那个去世的病人。去世的这个病人的癌细胞是完全失去了beta2M
production... 阅读全帖 |
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w********i
发帖数: 389 | 16 我的背景非常mathc这个职位，无奈网投如石沉大海。跪求内退，大大的包子。
Job Description - Bioinformatics Scientist/Engineer with Next Generation
Sequencing (036877)
Job Description
Bioinformatics Scientist/Engineer with Next Generation Sequencing
Bioinformatics Scientist / Engineer with Next Generation Sequencing – (
Briarcliff Manor, NY)
Your challenge:
Lend your experience and knowledge to help expand our clinical
bioinformatics team in order to help improve healthcare solutions for
patients and medical staff.
Your responsibi... 阅读全帖 |
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l**i
发帖数: 8144 | 17 简单地讲 就是谋事在人 成事在天
认为社会发展沿着某个预定方向发展的理论 都是傻逼理论
--------------------------------------
Anthropic principle
From Wikipedia, the free encyclopedia
In astrophysics and cosmology, the anthropic principle is the philosophical
argument that observations of the physical Universe must be compatible with
the conscious life that observes it. Some proponents of the argument reason
that it explains why the Universe has the age and the fundamental physical
constants necessary to accommodate conscious life. As a ... 阅读全帖 |
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T**********e
发帖数: 29576 | 18 人类基因不能专利， 但是cDNA可以专利。这个决定很让人奇怪。
A victory for genes
Nature Medicine (2013)
he decision has been a long time in coming—so long that Myriad's patents
were due to expire in less than three years. And the 15-year delay has
surely not aided patients who frequently benefit from healthy competition in
the biotech sector or from research on BRCA genes. Yet the decision brings
relief to those of us who reject the idea that an individual or corporation
can own—even for a limited time—human genes and there... 阅读全帖 |
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发帖数: 1 | 19 https://www.nature.com/articles/d41586-020-00364-2
Did pangolins spread the China coronavirus to people?
Genetic sequences of viruses isolated from the scaly animals are 99% similar
to that of the circulating virus — but the work is yet to be formally
published.
Researchers in Guangzhou, China, have suggested that pangolins — long-
snouted, ant-eating mammals often used in traditional Chinese medicine —
are the probable animal source of the coronavirus outbreak that has infected
more than 30,000... 阅读全帖 |
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c****3
发帖数: 10787 | 20 Researchers who have examined the genomes of two coronavirus infections in
Washington State say the similarities between the cases suggest that the
virus may have been spreading in the state for weeks.
Washington had the United States’ first confirmed case of coronavirus,
announced by the Centers for Disease Control and Prevention on Jan. 20.
Based on an analysis of the virus’s genetic sequence, another case that
surfaced in the state and was announced on Friday probably was descended
from that ... 阅读全帖 |
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M*P
发帖数: 6456 | 21 A postdoctoral position is available in the research group of Dr. Ivan
Ovcharenko at the National Institutes of Health (NIH). Our current research
projects include computational studies of epigenetic and sequence-based
mechanisms of gene regulation. We are developing computational approaches to
decipher the regulatory landscape of the human genome. By combining next
generation sequencing data with a large body of experimental enhancer
characterization, our computational approaches target transcr... 阅读全帖 |
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n*******w
发帖数: 687 | 22 跑了随机1000个元素的例子，取值范围为0-99。结果不对。
问题可能在于，得到一个sequence在hashmap里会残留下一些entry，导致接下来处理重
复元素出错。
比如残留的entry里有两个sequence [0 10] [6 12]。hashmap里会存在4个entry [0,11
] [10, 11] [6,7] [12 7]。如果下一个元素是11。合并两个sequence，得到长度为19
的sequence。其实不存在。
问题在于[12,7]是以12结尾的长度为7的序列。而以后访问的时候并不知道，把它当做
12开始长度为7的序列。而残留的entry里有很多这样的sequence，导致整个结果不对。 |
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p*****2
发帖数: 21240 | 23 一个String有sub string 和 sub sequence.
sub string大家都知道，sub sequence就是可以不连续的sub string。
比如abc, ab, bc 都是substring, 而ac不是。但是，ac也是sub sequence。
现在给两个String， s和t
那么在s里选取一个substring， 在t里选取一个sub sequence，使得他们相等。
问可以选取多少种组合。sub string , sub sequence 内容相等不要紧，只要有字符的
位置不同就认为是不同的string。
比如
s: "aa"
t: "aa"
ans: 5 |
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r***m
发帖数: 13 | 24 There is a sequence {a1, a2, a3, a4, ..... aN}. A run is the maximal
strictly increasing or strictly decreasing continuous part of the sequence.
Eg. If we have a sequence {1,2,3,4,7,6,5,2,3,4,1,2} We have 5 possible runs
{1,2,3,4,7}, {7,6,5,2}, {2,3,4}, {4,1} and {1,2}.
Given four numbers N, M, K, L. Count the number of possible sequences of N
numbers that has exactly M runs, each of the number in the sequence is less
than or equal to K and difference between the adjacent numbers is less than
eq... 阅读全帖 |
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l***i
发帖数: 1309 | 25 treat the sequence as a string and use KMP to match. You have to cut the
famous sequence at some point. Usually it is not a problem as most sequences
are increasing so you know you can stop when the last integer in your
sequence is smaller than the last one in the prefix of a famous sequence.
oeis is a website to do this search quite efficiently, not sure how they
implemented it. |
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S***w
发帖数: 1014 | 26 前面30分钟抓着问了我过去的经历，
做了一个小题目。
然后扔出这个大题 要求O(n)
且输出排序
我先用suffix array, 说不好
然后用hashmap, o(n), 但是输出不排行
恶心的地方，
输入不是string,是流
输出要排序
O(N)
最可气的是 找不到他想要的算法 不让写代码，
最后5分钟,找到他想要的答案，来不及了
好苦啊 为啥大家店面就那几道题，给我这么难的一个
This problem pertains to the field of bioinformatics, but it does not
require any specialized biological knowledge. All DNA is composed of
sequences of four "letters" of nucleotides, whose abbreviations are A, C, G,
and T, strung together, for example: "AAGATCCGTC". A typical chromosome (a
very long ... 阅读全帖 |
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S***w
发帖数: 1014 | 27 前面30分钟抓着问了我过去的经历，
做了一个小题目。
然后扔出这个大题 要求O(n)
且输出排序
我先用suffix array, 说不好
然后用hashmap, o(n), 但是输出不排行
恶心的地方，
输入不是string,是流
输出要排序
O(N)
最可气的是 找不到他想要的算法 不让写代码，
最后5分钟,找到他想要的答案，来不及了
好苦啊 为啥大家店面就那几道题，给我这么难的一个
This problem pertains to the field of bioinformatics, but it does not
require any specialized biological knowledge. All DNA is composed of
sequences of four "letters" of nucleotides, whose abbreviations are A, C, G,
and T, strung together, for example: "AAGATCCGTC". A typical chromosome (a
very long ... 阅读全帖 |
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s********o
发帖数: 493 | 28 抛砖引玉. 这题其实不算新题
一上来直接code，找小偷问题，有n个房间，其中一个房间有小偷。早上我们
可以打开一个房间的门看小偷在不在里面，晚上小偷会向左边或者右边的房间走。
现在给你一个开门的sequence，你输出这个sequence能不能保证找到小偷。
比如：如果只有三个房间那么如果打开房间的sequence是{1，1}那么一定会找到小偷。
因为如果小偷在中间那么第一天就会被找到，如果小偷在两边那么第二天一定回来
到中间也会被找到。房间数为n，sequence长度为k
跟着我开始brute force假设小偷在某个房间然后dfs所有路径，大概是O(n*n^k)。
考官说好，如果考虑cut branch呢？跟着我就说可以拿一个n*k的matrix跟着根据
sequence来cut branch，reduce到O(n*n*k)。他说有没有可能同时从所有房间
开始呢？我说可以跟着直接在那个n*kmatrix上做一个类似dp的东西。跟着reduce 到
O(n*k)。他说有没有可能把space reduce呢？我说可以我只要O(n)的space
跟着他就让我再写一个叫nextRow的f... 阅读全帖 |
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j****0
发帖数: 55 | 29 The Oral Pathogen Genome Sequence Database (ORALGEN) at Los Alamos National
Laboratory is seeking highly motivated graduate research assistants (GRA) or
visiting Scholar to work on our bioinformatics team to perform sequence
analysis and annotation. Our focus is on oral pathogen genomes and the
upcoming oral community metagenome sequence data. The work will involve
running sequence analysis software, analyzing genes by DNA/protein sequence,
and genomic structure, mining various gene annotation |
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d***n
发帖数: 12 | 30 寻找Genomics方面的专家
我们也想借未鸣空间的宝地，公开求贤，寻找Genomics方面的专家，共同创业。
专业方向:
Next Gen DNA sequencing
Roche 454 Genome Sequencer FLX Standard and FLX Titanium
Solexa technology
Applied Biosystems SOLiD
Whole Genome Analysis
PCR Amplicon Sequencing
Metagenomics
Transcriptomics
Small RNA Analysis
Epigenetics
Genome sequencing and re-sequencing
ABI 3730xl, 3130xl
Amersham MegaBACE 4000 and 1000
文库构建
cDNA libraries (including standard cDNA library, large insert cDNA library,
normalized cDNA library and subtracted c |
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n****x
发帖数: 11 | 31 Probe Design Scientist Position – R&D
Advanced Cell Diagnostics, Inc. (ACD) is a leader in the field of molecular
pathology and tissue-based diagnostics. Our core RNAscope® technology is
the world’s first multiplex fluorescent and chromogenic in situ
hybridization platform capable of detecting and quantifying RNA biomarkers
in situ at single molecule sensitivity. RNAscope is an ideal platform for
developing next-generation tissue-based molecular diagnostics. We are
committed to continued inn... 阅读全帖 |
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j*x
发帖数: 30 | 32 Responsibilities:
• Testing and understanding of the established NGS sequencing
pipelines, such as RNA-Seq pipeline and Deep-sequencing mutation pipeline;
• Providing support for the NGS analysis of whole SMAB group;
• Understanding of the algorithms used in the standard software and
building new pipelines;
• Working with the modeling persons to develop software interfaces
for their developed algorithms.
Advantages of this position: The candidate will work clo... 阅读全帖 |
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b*******m
发帖数: 3 | 33 Hiring unit:
Garmire Group (PI starting 09/01/2012, the postdoc position available 09/01
or later) )
University of Hawaii Cancer Research Center
Job description:
Located on the beautiful sea shore of Honolulu, Hawaii, overlooking the
Pacific Ocean, the University of Hawaii Cancer Center (UHCC) is one of only
66 research organizations in the country designated by the National Cancer
Institute. Its mission is to focus on key cancers that impact the multi-
ethic population of Hawaii, as well as wor... 阅读全帖 |
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g****d
发帖数: 238 | 34 【 以下文字转载自 Biology 讨论区 】
发信人: gifted (sentosa), 信区: Biology
标 题: call for reviewers (转载)
发信站: BBS 未名空间站 (Wed Apr 5 23:38:57 2017, 美东)
发信人: gifted (sentosa), 信区: EB23
标 题: call for reviewers
发信站: BBS 未名空间站 (Wed Apr 5 21:03:58 2017, 美东)
OAP 旗下 International Journal of Clinical Microbiology，无分非SCI哦，稿件情
况如下：
Title: Transcription regulators MarA, SoxS and Rob and CTX-M beta-lactamase
gene sequences as potential diagnostic biomarker in monitoring and
management of antibiotic treatment
Abstract:
Abs... 阅读全帖 |
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g****d
发帖数: 238 | 35 【 以下文字转载自 EB23 讨论区 】
发信人: gifted (sentosa), 信区: EB23
标 题: call for reviewers
发信站: BBS 未名空间站 (Wed Apr 5 21:03:58 2017, 美东)
OAP 旗下 International Journal of Clinical Microbiology，无分非SCI哦，稿件情
况如下：
Title: Transcription regulators MarA, SoxS and Rob and CTX-M beta-lactamase
gene sequences as potential diagnostic biomarker in monitoring and
management of antibiotic treatment
Abstract:
Abstract
Extended Spectrum Beta Lactamases (ESBLs) are resistance enzymes that are
responsible for antibiotic resista... 阅读全帖 |
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l******n
发帖数: 520 | 36 最近实在太多人跟我要PL。。。也很多人跟我要review。。。
(一)PL
PL涉及太多个人信息，删除这些个人信息后我觉得实在没什么借鉴意义。我是如何写PL
，在前贴也有讲过。现将我的PL中大家可能参考的部分贴上来（主要是开头和结尾几个
段落），至于中间部分，我觉得真的需要自己根据自己的研究项目好好写，多写，多改
，找不同的人帮看，提意见，别的没有什么好办法。
（二）review
这个比较容易攒，大家也很下功夫。但是我的原则是我不会找研究领域跟稿件差别大的
reviewer。而且我接的稿子非常少，希望大家理解。
最后祝大家好运！
Feb 23, 2011
RE: I-140 Immigrant Petition for Alien of Extraordinary Ability
Petitioner/Beneficiary: Dr. Pig Monkey, PhD
Classification Sought: 203(b)(1)(A)
Dear Immigration Officer,
... 阅读全帖 |
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g****d
发帖数: 238 | 37 OAP 旗下 International Journal of Clinical Microbiology，无分非SCI哦，稿件情
况如下：
Title: Transcription regulators MarA, SoxS and Rob and CTX-M beta-lactamase
gene sequences as potential diagnostic biomarker in monitoring and
management of antibiotic treatment
Abstract:
Abstract
Extended Spectrum Beta Lactamases (ESBLs) are resistance enzymes that are
responsible for antibiotic resistance and are produced by the CTX-M beta-
lactamase gene in Gram-negative pathogens, such as antibiotic resistant
Escherichia ... 阅读全帖 |
|
n******2
发帖数: 11 | 38 大费城地区的兄弟姐妹请看过来，儿童医院临床分子诊断室招人作whole exome
sequencing data analysis (more specifically, variant analysis-to find the
underlying pathogenic mutation out of thousands of sequence variants in
patient's exome). No bioinformatics background required.
欢迎直接网上申请:
https://www.chop.edu.apply2jobs.com/ProfExt/index.cfm?fuseaction=mExternal.
showJob&RID=30613
Requisition #: 13-30613
Job Title: Whole Exome Sequencing Data Analyst (The Children's Hospital
of Philadelphia)
City: Philadelphia
State: ... 阅读全帖 |
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m***n
发帖数: 337 | 39 we have a senior scientist openning for bioinformatics and below is the job
description and if you are interested and you could forward your resume to
me at m******[email protected]
POSITION SUMMARY
Intrexon is currently seeking to fill a Senior Scientist, Bioinformatics
position within the Cell Systems Informatics group, in San Diego. The senior
scientist will be responsible to for developing and performing state-of-the
-art bioinformatics analyses, implementing novel applications and workflows
in se... 阅读全帖 |
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j****n
发帖数: 4358 | 40 【 以下文字转载自 JobHunting 讨论区 】
发信人: Solow (Solow), 信区: JobHunting
标 题: L家第一轮店面 被烙印黑了
发信站: BBS 未名空间站 (Mon Feb 23 16:58:15 2015, 美东)
前面30分钟抓着问了我过去的经历，
做了一个小题目。
然后扔出这个大题 要求O(n)
且输出排序
我先用suffix array, 说不好
然后用hashmap, o(n), 但是输出不排行
恶心的地方，
输入不是string,是流
输出要排序
O(N)
最可气的是 找不到他想要的算法 不让写代码，
最后5分钟,找到他想要的答案，来不及了
好苦啊 为啥大家店面就那几道题，给我这么难的一个
This problem pertains to the field of bioinformatics, but it does not
require any specialized biological knowledge. All DNA is composed of
sequences of four "letters" of nucl... 阅读全帖 |
|
g*********r
发帖数: 1443 | 41 对你的问题的细节不清楚。
如果你有一个genome的sequence，想知道这个genome和哪个species最接近，你需要的是几个fish的sequence，和reptile，bird， mamal的sequence。可以做whole
genome alignment。Bowtie似乎更适合multiple sequence向已知reference的mapping。
如果你有的是一段sequence，直接blast就是了。 |
|
a*****g
发帖数: 19398 | 42 Deep Learning Isn’t a Dangerous Magic Genie. It’s Just Math
Deep learning is rapidly ‘eating’ artificial intelligence. But let’s not
mistake this ascendant form of artificial intelligence for anything more
than it really is. The famous author Arthur C. Clarke wrote, “Any
sufficiently advanced technology is indistinguishable from magic.” And deep
learning is certainly an advanced technology—it can identify objects and
faces in photos, recognize spoken words, translate from one language to
another... 阅读全帖 |
|
|
p****r
发帖数: 9164 | 44 The following is copy&paste from the blog I posted before. Hopefully no
copyright issue.
Running it twice is great for risk-reverse. I really do not mind the
extra 1$ rake since I only do it a few times a day at most. Guess it is
worth more in NL 200 and NL 400. Unless you have unlimited BR(over 200bi),
this is great way to reduce variance. When you look at these high risk game
(Poker, stock etc) , EV is not the only thing you should consider, reducing
variance is very important as well... 阅读全帖 |
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p****r
发帖数: 9164 | 45 It is the same.
This is from the blog a of Ph.d student @ CMU CS, studying AI and
game theory in poker.
" In the previous examples we assumed the cards were dealt with
replacement; but in reality they are not. Does this change anything? It isn'
t obvious at all, but it turns out that your expected payoff is the same in
both settings.
Let P be the size of the pot.
Let p be the probability P1 wins the first hand.
Let w be the probability P1 wins the second hand given he wins the ... 阅读全帖 |
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M*****e
发帖数: 11621 | 46 为了你严谨的学术态度，我又写了一遍，但我语言组织能力差，看上去似乎更长了……
主要是在C_n <-> B_n 这段，为了和前面的可以无缝连接，我把它反过来写了，原帖
的方向描述更简单些。
A_n = {n pairs of parentheses in the Catalan sense}
B_n = {321-avoiding permutations in S_n}
C_n = {n-integer sequence with c_1 = 1, and 1 <= c_i <= c_{i-1} + 1 for i>=
2}
A_n <-> C_n: take any t in A_n, and reconstruct it according to the order of
“)”, from left to right. The corresponding element in C_n is built by the
number of components c_i at each stage. For example, ()(()) is
reconstructed as ()... 阅读全帖 |
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d***n
发帖数: 12 | 47 寻找Genomics方面的专家
我们也想借未鸣空间的宝地，公开求贤，寻找Genomics方面的专家，共同创业。
专业方向:
Next Gen DNA sequencing
Roche 454 Genome Sequencer FLX Standard and FLX Titanium
Solexa technology
Applied Biosystems SOLiD
Whole Genome Analysis
PCR Amplicon Sequencing
Metagenomics
Transcriptomics
Small RNA Analysis
Epigenetics
Genome sequencing and re-sequencing
ABI 3730xl, 3130xl
Amersham MegaBACE 4000 and 1000
文库构建
cDNA libraries (including standard cDNA library, large insert cDNA library,
normalized cDNA library and subtracted c |
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d***n
发帖数: 12 | 48 寻找Genomics方面的专家
我们也想借未鸣空间的宝地，公开求贤，寻找Genomics方面的专家，共同创业。
专业方向:
Next Gen DNA sequencing
Roche 454 Genome Sequencer FLX Standard and FLX Titanium
Solexa technology
Applied Biosystems SOLiD
Whole Genome Analysis
PCR Amplicon Sequencing
Metagenomics
Transcriptomics
Small RNA Analysis
Epigenetics
Genome sequencing and re-sequencing
ABI 3730xl, 3130xl
Amersham MegaBACE 4000 and 1000
文库构建
cDNA libraries (including standard cDNA library, large insert cDNA library,
normalized cDNA library and subtracted c |
|
w*****n
发帖数: 353 | 49 1.
A binary gap within a positive integer N is any maximal sequence of
consecutive zeros that is surrounded by ones at both ends in the binary
representation of N.
For example, number 9 has binary representation 1001 and contains a binary
gap of length 2. The number 529 has binary representation 1000010001) and
contains two binary gaps: one of length 4 and one of length 3. The number 20
has binary representation 10100 and contains one binary gap of length 1.
The number 15 has binary representati... 阅读全帖 |
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c**m
发帖数: 30 | 50 要处理些数据，用map,set,recursion搞搞，结果有点慢。有没有好的algorithm?
Data can be quite large.
Given a list of sequences, each of which is a combination of ids, group the
sequences that share at least one id into a single sequence composed of all
the unique ids.
For example, say sequences are people's names, group people who share first
and/or last name.
ie.
John Smith
Paul Smith
John Hunt
Paula Foster
Kelly Foster
Chapman Kelly
would give two new sequences:
John Smith Paul Hunt
Paula Foster Kelly Chapman |
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