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s******y
发帖数: 28562
1

在我的理解中应该不需要,因为那3个内容在大部分情况下就不应该和authentication
of key biological and/or chemical resources有关。
t********9
发帖数: 536
2
是不是既分开来写 (用小标题,方便Reviewer找到),又融入到Approach中去,这样
最保险。
s******y
发帖数: 28562
3

我的理解是对于1,2,3, 你每写一个具体的specific aim 的时候都必须单独提出来
。所以你在那个12页的正文里其实是每个大段落都必须有Premise, Rigorous, and
other considerations这三个小段落。我觉得Premise其实就是以前的那个Rationale的
等价品, 而Rigorous, and other considerations差不多就是以前的那个pitfall and
alternative resolution 的代替品。这个是我的理解,不知道对不对。希望参加了今
年的review panel 的人来说说。
H****y
发帖数: 2992
4
我有个challenges and alternative strategies了。我还想单列个2号,看能不能写出
来。
我是总的sig, innovation,然后在approach里分具体的aims。这样每个就写一次了。
我觉得这个东西必须pass,但还不是决定别人喜不喜欢的因素,所以不是太担心。

and
j*****r
发帖数: 48
5
I got my summary statement for a June R01 already. There were specific
mentions on the Biological Variables and Rigor requirements in the comments
of the reviewers.
I agree with you that these are not the content that will make a proposal
fundable. But these days the payline is so low, a few points knocked off for
these guidelines could be the difference between funded vs. unfunded.
t********9
发帖数: 536
6
多谢胖老师和高妹!
我写的Proposal 也是总的 significance, innovation, 然后在Approach里列出3个
Aim。 我是想在总的Siginificance里写个总的Scientific Premise,这样比较适合我
的研究工作。对我的 各个Aim,非要写出个Scientific Premise,好像不太合适。
s******y
发帖数: 28562
7
我建议你把challenges and alternative strategies改名为Considerations for
Vigorous and Biological Variants
t********9
发帖数: 536
8
胖老师,我觉得rigorous and other considerations,不应该简单理解成那个pitfall
and alternative resolution的替代品,但可以是其中的一部分,这个pitfall and
alternative resolution, 还应该包括了mechanism 等方面的讨论。

and
H****y
发帖数: 2992
9
谢谢你的指导。
关于这个处在分界线的分数,我是这么看的,不一定对。表面上,有些分数很close,
好像和被funded差不多。事实上,人家想不想fund你,是非常明确的yes and no。很多
就是坏在,看似很近,总觉得有希望,就试了又试,但其实永远都不会中。喜欢你,就
少挑毛病,你就上去了。不喜欢你,总能在一些琐碎的地方找出这个那个的毛病。我原
先老错误的认为,只要我resubmit能把这些毛病解决,分就过线了。但总是“差那么一
点点”。根源在,不是这些小毛病的问题,是人家根本不喜欢啊。

comments
for
s******y
发帖数: 28562
10
可是我觉得第二条:
rigorous experimental design for robust and unbiased results,
这个难道不就是以前的有关mechanism 等方面的讨论么?就是你的实验设计必须把其他
可能的假设以及可能性包含进去的吧?

pitfall
j*****r
发帖数: 48
11
Agreed. If this is the case, it may be best to switch the study section.
H****y
发帖数: 2992
12
来感谢下你吧!好像我们的grant office不懂。他们回信就是说要加多那个文件4. 你
要是不来问,我还真不知道。
A******y
发帖数: 2041
13
来自主题: Faculty版 - 施一公去哈佛挖老师 (转载)
It is not easy to go back. I have no connection with China, I came during
my high school years. I send some application to different schools...
absolutely no reply. Not a big bull in the US, but I have a seat at a NIH
study section. Btw, the NIH study section is not that bad, we don't fully
look at people's publications because there are a lot of bullshit (yes, even
NSC). Do you think that I will give someone a pass on a grant if I cannot
reproduce their results?
Second, a private institute... 阅读全帖
f**********d
发帖数: 4960
14
来自主题: Faculty版 - 帮忙下载一篇论文 (转载)
【 以下文字转载自 Military 讨论区 】
发信人: freelikewind (像风一样自由), 信区: Military
标 题: 帮忙下载一篇论文
发信站: BBS 未名空间站 (Wed Oct 30 15:19:55 2019, 美东)
从ieee下载的
draft图不对
From sample similarity to ensemble similarity:
Probabilistic distance measures in
reproducing kernel Hilbert space
发到harrypotter0601 at gmail.com。谢谢了!
g******t
发帖数: 11249
15
- 与国内年轻PI共勉
【序:对每一位刚刚在清华大学生命科学学院或医学院建立独立实验室的年轻PI(
Principal Investigator),我都会不止一次地忠告:至少要在前三年,你们一定要把
自己当成超级博士后,身先士卒、尽全力地在实验室做研究、做自己的课题,同时训练
培养博士生、实验员和博士后。只要能够重复你们博士生和博士后阶段的辉煌,你们就
不愁在清华拿不到tenure!】
普林斯顿的offer
1997年3月27日下午,在纽约市Memorial Sloan-Kettering Cancer Center的实验
室里,我接到了来自普林斯顿大学分子生物学系教授Tom Silhavy的电话,“Yigong, I
am calling to tell you a piece of good news. Our faculty voted unanimously
to offer you a position, at the level of Assistant Professor.”我喜不自胜,
“Great!” Tom接着说,“We will be happy to discu... 阅读全帖
c*******r
发帖数: 527
16
Marriage is different from sex, more of a goverment-endowed and forced
mutual commitment to each other. It should require some emtional connection,
but not necessary have to. A lot of people got married before they
understood what was going on. People who are not suitable for marriage
should stay out, just like people who don't want kids should not reproduce.
Failed marriages are because of people, not marriage itself. Simple.
k***n
发帖数: 11247
17
来自主题: Family版 - 就是动物都有追求幸福的权利

survival of the fittest. if they're positions at the bottom, means they're
not fit to reproduce. isn't it natural?
k***n
发帖数: 11247
18
不是的,this theory applies everywhere in the world. women can get married/or have children easily if they want. but men have to be successful in order to reproduce.
q*****4
发帖数: 314
19
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单张面值:
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可接受价格(必须明码标价!):
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物品新旧要求:
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邮寄方式要求:
regular mail
买卖双方谁承担邮寄损失(Required if not code only):
付款方式说明:
BOA/paypal
其他补充说明:
On the reverse side of the card it states:
Offer valid through 2/28/11. This offer is valid for one time use on
merchandise only in Coach stores in the US, Canada and Puerto Rico. This
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w*y
发帖数: 606
20
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二手交易风险自负!请自行验证是否合法和一手卡!:
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Offer valid through 2/28/11. This offer is valid for one time use on
merchandise only in Coach stores in the US, Canada and Puerto Rico. This
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w*y
发帖数: 606
21
来自主题: FleaMarket版 - [出售]COACH COUPON $100 OFF $300
up

二手交易风险自负!请自行验证是否合法和一手卡!:
我想卖的物品:
COACH COUPON $100 OFF $300
Offer valid through 2/28/11. This offer is valid for one time use on
merchandise only in Coach stores in the US, Canada and Puerto Rico. This
offer is not valid at Coach Factory Stores, Department Stores, Mohegan Sun
or coach.com. Not valid on merchandise holds, phone orders, web store
pickup or purchase of gift cards. No adjustments on previous purchases.
Cannot be combined with any other offer or discounts. Discount is not
applica... 阅读全帖
d********e
发帖数: 6814
22
大妈群老相好,免费。。。只能店里用,27号截止
否则10个包子。。。
Bonus Certificate excludes BCBGMaxAzria, FitFlop, Folli Follie, Gentle
Souls, Herve Leger, Michael Michael Kors, Nicole Miller Bridal,
Stuart Weitzman, Ugg & Under Armour; ladies' cashmere; cosmetics, fragrances
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Fifth Avenue Swarovski Shop; charity-related merchandise; candy, gourmet,
gift cards, internet orders, phone orders,
restaurants, Beauty Salon, store services, prior purchases or as account
payment. Lord & Tayl... 阅读全帖
h*********g
发帖数: 799
23
RT, 40 purchase required
In store purchase only, valid through 09/25.
Probably can be used to purchase clinique ,estee lauder and so on
Bonus certificate not valid on BCBGMaxAzria, FitFlop, Folli Follie, Gentle
Souls, Herve Leger, Michael Kors Jewelry, Nicole Miller Bridal, Stuart
Weitzman, UGG® Australia & Under Armour; ladies' cashmere; cosmetics,
fragrances & beauty accessories; all fashion watches; Fifth Avenue Swarovski
Shop; charity-related merchandise; candy, gourmet, gift cards, int... 阅读全帖
u*****x
发帖数: 32
24
请仔细阅读以下条款,确定适用:

Type: Domestic Economy Class Companion Certificate* for discounted
travel
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a****u
发帖数: 272
25
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第一个人买Delta机票,可以再花99带上第二个人。买前请仔细阅读T&C。
我发code给你,你paypal,BOA,Chase给我 $100。
有效期01/31/2014
有问题PM。
Terms and Conditions
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Eligible on Delta, Delta Connection carrier and Delta Shuttle flights only (
excludes all other Delta-designated codeshare flights). Companion
certificate is valid for one discounted round-trip Economy Class companion
ticket with the purchase of certain adult round-trip fares on published
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G*****u
发帖数: 1222
26
通过网站redeem
https://www.delta.com/edocviewer/redeem_cert/index.jsp
06/30/2013过期
可同时出售delta里程25K at 1.2c
Domestic Economy Class companion certificate for discounted travel allows
Gold Delta SkyMiles Cardmembers to bring a friend for a $99 Companion Ticket
fee plus $10.80-27.60 in government taxes and fees (depending upon the
itinerary) with the purchase of certain adult round-trip fares on published
routings within the 48 contiguous United States.
Residents of Hawaii and Alaska must originate from... 阅读全帖
G*****u
发帖数: 1222
27
通过网站redeem
https://www.delta.com/edocviewer/redeem_cert/index.jsp
06/30/2013过期
可同时出售delta里程25K at 1.2c
Domestic Economy Class companion certificate for discounted travel allows
Gold Delta SkyMiles Cardmembers to bring a friend for a $99 Companion Ticket
fee plus $10.80-27.60 in government taxes and fees (depending upon the
itinerary) with the purchase of certain adult round-trip fares on published
routings within the 48 contiguous United States.
Residents of Hawaii and Alaska must originate from... 阅读全帖
b****a
发帖数: 460
28
来自主题: FleaMarket版 - [出售]Delta Companion Certificate $99
第一个人买Delta机票,可以再花$99+tax带上第二个人。买前请仔细阅读T&C。
我给发code,你转账到我BOA或者paypal
有效期03/31/2014
Terms and Conditions
Eligibility:
Eligible on Delta, Delta Connection carrier and Delta Shuttle flights only (
excludes all other Delta-designated codeshare flights). Companion
certificate is valid for one discounted round-trip Economy Class companion
ticket with the purchase of certain adult round-trip fares on published
routings within the 48 contiguous United States. Residents of Hawaii and
Alaska must originate... 阅读全帖
b****a
发帖数: 460
29
来自主题: FleaMarket版 - [出售]Delta Companion Certificate $99
第一个人买Delta机票,可以再花$99+tax带上第二个人。买前请仔细阅读T&C。
我给发code,你转账到我BOA或者paypal
有效期03/31/2014
Terms and Conditions
Eligibility:
Eligible on Delta, Delta Connection carrier and Delta Shuttle flights only (
excludes all other Delta-designated codeshare flights). Companion
certificate is valid for one discounted round-trip Economy Class companion
ticket with the purchase of certain adult round-trip fares on published
routings within the 48 contiguous United States. Residents of Hawaii and
Alaska must originate... 阅读全帖
w*****s
发帖数: 2689
30
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一个人订Delta的美国国内航班,另一个人只需要付少量的tax(30左右)就可以买到一
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因为规定必须要skymiles的credit card,所以我可以替你订机票,然后你把所花的钱
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$195)
付款方式: Paypal,BOA
有效期 07/31/2013
联系方式:PM
请仔细阅读 Terms&Conditions:
PLATINUM COMPANION CERTIFICATE
Eligibility:
Eligible on Delta, Delta Connection carrier and Delta Shuttle flights only (
excludes all other Delta-designated codeshare flights). Companion
certificate is valid for one round-trip Economy Class companion ticket with
the purcha... 阅读全帖
w*****s
发帖数: 2689
31
来自主题: FleaMarket版 - [出售] Delta Platinum Companion Certificate
一个人订Delta的美国国内航班,另一个人只需要付少量的tax(30左右)就可以买到一
张同行的机票。
要价: $195
因为规定必须要skymiles的credit card,所以我可以替你订机票,然后你把所花的钱
加上$195 打给我 (如果你自己有skymiles信用卡,我可以把code发给你,你只需要付
$195)
付款方式: Paypal,BOA
有效期 07/31/2013
联系方式:PM
请仔细阅读 Terms&Conditions:
PLATINUM COMPANION CERTIFICATE
Eligibility:
Eligible on Delta, Delta Connection carrier and Delta Shuttle flights only (
excludes all other Delta-designated codeshare flights). Companion
certificate is valid for one round-trip Economy Class companion ticket with
the purcha... 阅读全帖
m*****s
发帖数: 1471
32
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a*****0
发帖数: 86
33
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站内信
prefer Paypal
Detail
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on merchandise only in Coach stores in the continental U.S., Canada, Puerto
Rico, Hawaii and online at coach.com until 11:59PM EST on the last day of
the valid period. This offer is not valid on the purchase of capsule
collection items, the Borough Bag or the Urbane Bag. This offer
is not valid at Coach Factory stores, Coachfactory.com, Coach Herald Square,
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s*********3
发帖数: 573
34
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3月31日过期, 适合春假。
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the purchase of certain adult round-trip fares on published routings within
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s**n
发帖数: 1127
35
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一个人订Delta的美国国内航班,另一个人只需要付 $99+ 少量的tax(30左右)就可以
买到一
张同行的机票。
要价: $100
因为规定必须要skymiles的credit card,所以我可以替你订机票(两人机票),然后
你把所花的钱加上$100 打给我.
付款方式:BOA
有效期 10/31/2014,必须在此日期前完成travel
联系方式:PM
请仔细阅读 Terms&Conditions:
PLATINUM COMPANION CERTIFICATE
Eligibility:
Eligible on Delta, Delta Connection carrier and Delta Shuttle flights only (
excludes all other Delta-designated codeshare flights). Companion
certificate is valid for one round-trip Economy Class companion ticket with
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l********3
发帖数: 45
36
Yamaha YDPS31 Arius Console Piano with Folding Key Cover, 3-Pedal Cabinet
亚马逊2012年购买的,即将搬家打算出售,有意者站内联系或发邮件
luokai1103 .at. gmail.com
http://www.amazon.com/gp/product/B001TQ0CX4/ref=od_aui_detailpages00?ie=UTF8&psc=1
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p******a
发帖数: 1355
37
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我想卖的物品:
lord & Taylor 20 off 40 Bonus Card (Valid only from 5/5/15 to 5/11/15)
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物品新旧要求:
邮寄方式要求:
PDF
买卖双方谁承担邮寄损失(Required if not code only):
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non cc paypal
其他补充说明:
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till gone
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c**i
发帖数: 6973
38
来自主题: Food版 - eel
James Prosek, Mystery Travelers; They spend decades in rivers and lakes,
then cross oceans and spawn in secret. National Geographic, September 2010.
http://ngm.nationalgeographic.com/2010/09/eels/prosek-text
Quote:
(a) American cooking:
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s*******i
发帖数: 1063
39
trust me, you cannot reproduce that
I tried many different recipe, not sure if the banana was different or not,
they are either too sweet (like Jun zhi's recipe), or not rich in banana
flavor.
z***h
发帖数: 405
40
【 以下文字转载自 Overseas 讨论区 】
发信人: Knite (nii), 信区: Overseas
标 题: 上海交通大学世界大学排行榜数据造假的论文 zz
发信站: BBS 未名空间站 (Wed Aug 8 23:35:50 2007)
http://web.wenxuecity.com/BBSView.php?SubID=college&MsgID=36597
笔者近日据悉,世界顶级学术科学计量学术期刊Scientometrics,刊登了关于上海交通
大学世界大学排行榜数据造假的论文。
论文题名为:Irreproducibility of the results of the Shanghai academic
ranking of world universities
论文概要为:I discuss the difficulties that I encountered in reproducing the
results of the Shanghai ranking of world universities. In the Shanghai
ranking,
a******s
发帖数: 4052
41
来自主题: HiFi版 - 山水221 真是不错
时代不同啊。那个山水全模拟电路,声音比较暖。
Technics SA-290 is a solid state amplifier. It was manufactured from 1986 to
unknown.
quartz synthesizer digital tuning, soft touch, phono -tape-CD inputs
Based on an IC output module rated at 50W for only 0.02% THD - with internal
overload protection.
The integrated IC module faithfully reproduces any phono, radio or CD input
with very little noise or distortion
The digital AM / FM tuner has an LED display and easy station tuning and
memory store functions
Speakers can be
V*****n
发帖数: 893
42
my current problem is the IQ3 has a steep roll off at the bass. the effect
of now-you-hear-it and now-you-don't is very evident. it reproduces drum
sometime unnaturally, because only part of the frequency is there. now the
ar94 made me realized the natural sound of a gentle bass roll-off from a
sealed box is not something I can live without (it doesn't have to go very
deep). but I don't know if a sub can blend in easily. also, I wonder if they
will be as natural as true full range speakers.
d******0
发帖数: 22800
43
来自主题: HiFi版 - TF 10不过如此
单元是不是就是driver啊,Three individual armature speaker drivers reproduce
low, mid and high frequencies 。。
一个耳机里是不是有3个单元。。那不就是60到90美元了。
C********n
发帖数: 6682
44
来自主题: HiFi版 - TF 10不过如此
他说的是三个单元加起来2-30
单元本身就不贵

reproduce
o****e
发帖数: 916
45
来自主题: HiFi版 - Okeoke 鼠标不见了
不好意思,好像是有这个问题,2.3.8.3问题严重些,最新的2.3.8.5应该好些。请问你
运行的是最新版本么?能不能详细说一下鼠标消失后,不能出现是怎么触发的?是不是
很容易reproduce?
o****e
发帖数: 916
46
来自主题: HiFi版 - Okeoke 鼠标不见了
不好意思,好像是有这个问题,2.3.8.3问题严重些,最新的2.3.8.5应该好些。请问你
运行的是最新版本么?能不能详细说一下鼠标消失后,不能出现是怎么触发的?是不是
很容易reproduce?
l**v
发帖数: 188
47
I know this is very subjective. However, since it's kind of difficult for me
to test all brands/models, I'm trying to get some recommendations from the
experienced ppls on this board for some "liked by most" models to start with.
Since I'm building from scratch, I'm very open to options. My budget will be
probably 2~3k including speakers, receiver and DAC. I don't have many CDs,
but a lot of APEs, so I can live with my PS3 for CDs for the time being. I
mostly listen to symphonies and vocals. I a... 阅读全帖
m*d
发帖数: 7658
48
来自主题: HiFi版 - 先锋100刀的BS41 90了
你前面给的link,安桥说出问题的比率小于0.3%,很难reproduce,结果还没有fix这个
bug
j*********r
发帖数: 24733
49
跳吧,quote:
The Proline 750's reproduce the sound of musical instruments better than any
other headphone I've ever heard, IMO.
http://www.head-fi.org/t/343241/ultrasone-proline-750-vs-sennhe
D**********s
发帖数: 3139
50
来自主题: HiFi版 - 能推荐一个$400左右的DAC么
音量控制对音质的影响,以前有一篇note写得不错,我找了半天才找到,其实还有用变
压器的方法,不过dac这块最保真的方法就是保持位深和标准输出电平,音量控制交给
前级和功放去管就好了,终究绕不过模拟放大这一关的。
Volume Control Technologies
Newsletter Edition:
July 2009 Issue
With the introduction of Benchmark’s HDR-VC™ (High Dynamic Range
Volume Control), many audio enthusiasts are taking another look at volume
control methods. What are the differences between the different volume
control topologies? Is one sonically superior, and why?
The important qualities to consider with respect to volum... 阅读全帖
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