s**i
发帖数: 4448 | 1 Sounds fishy to me. Unless it was a misdiagnose to begin with.
Metastatic cancer is pretty much a death sentence. |
|
s**i
发帖数: 4448 | 2 I just don't believe that story.
A patient with confirmed metastatic cancer beyond treatment lived for 10
years just on CTM. |
|
g***t
发帖数: 7544 | 3 人说“我邻居当时癌症直接被判死刑了，预期是半年以内，跑了好几个
大医院结论类似。后来只能看中医了，结果多活了将近10年。”你怎么
得出结论是“metastatic cancer”？
你自己补进了太多细节，做出了太多预设。 |
|
w***u
发帖数: 17713 | 4 metastatic solid tumor...
我比较看得开，即使我是个billionaire可能都不看了 -- 如果可以安乐死的话，多出
这痛苦的半年干哈呢？ |
|
s**r
发帖数: 669 | 5 谁知道Metastatic是内因（某些基因突变）还是外因（过度疲劳，压力大）导致内因？ |
|
s**r
发帖数: 669 | 6 也许有少数幸运者属于outlier可以活得长久一些，另外还是那篇论文，提到Despite
advances, 20% to 30% of patients with early breast cancers will experience
relapse with distant metastatic disease.
出现转移的概率应当高于5% |
|
G****e
发帖数: 11198 | 7 【 以下文字转载自 Biology 讨论区 】
发信人: Evangeline4 (Evangeline4), 信区: Biology
标 题: 两篇一模一样的文章(2012, 2015)
发信站: BBS 未名空间站 (Tue Oct 6 13:38:32 2015, 美东)
The microRNA-1246 promotes metastasis in non-small cell lung cancer by
targeting cytoplasmic polyadenylation element-binding protein 4
(Weihua Huang, Huifen Li, and Rongcheng Luo, 2015, Diagnostic Pathology
Journal)
MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic
polyadenylation element-binding protein 4 in hepatocellular carci... 阅读全帖 |
|
h*******r
发帖数: 847 | 8 http://www.ncbi.nlm.nih.gov/m/pubmed/23284890/
CDA-2, a urinary preparation, inhibits lung cancer development through the
suppression of NF-kappaB activation in myeloid cell.
Wang X, et al. PLoS One. 2012.
Show full citation
Abstract
CDA-2 (cell differentiation agent 2), a urinary preparation, has potent anti
- proliferative and pro-apoptotic properties in cancer cells. However, the
mechanisms of tumor inhibitory action of CDA-2 are far from clear, and
especially there was no report on lung canc... 阅读全帖 |
|
l*******1
发帖数: 16217 | 9 CRISPR 这个绝对该得，我刚才查了一下 中国和美国FDA 今年已经批准肺癌试验了，前
面英国的报道过治愈过白血病，
The Chinese trial will enrol patients who have metastatic non-small cell
lung cancer and for whom chemotherapy, radiation therapy and other
treatments have failed. “Treatment options are very limited,” says Lu. “
This technique is of great promise in bringing benefits to patients,
especially the cancer patients whom we treat every day.”
Leukaemia success heralds wave of gene-editing therapies
Lu’s team will extract immune cells called T... 阅读全帖 |
|
发帖数: 1 | 10 11 月13日 终于找到另一股在我家害我的势力
昨天，这些人折腾了一天，白天，晚上皮啦啦，也不知道谁把谁杀了，谁把谁带走了。
反正我先生和孩子被绑架了，就不知道是不是已经遇害了。我本来是打算睡觉的，但他
们头上，地下装电磁波攻击器，让我几乎窒息。虽然我没倒下，但其实他们在我身上扎
的毒针已经蔓延，我能感觉到我的呼吸有窒息的感觉。我想我对他们已经非常仁慈了，
但他们不依不饶地攻击我，欲置我于死地，让我非常生气，特别是肆意伤害我家里的人
，绑架我先生和孩子，而且有许许多多无辜的生命毁于他们之手，有必要把他们曝光。
当然我还没分析这里边是那几个人具体攻击我，伤害我的，但他们显然都是一伙的。鉴
于他们伤害我的头部，胸部 和胃部，我就把这几部分的医生都曝光，受害者慢慢去调
查，追查他们吧。
Cleveland Clinic, Website: my.clevelandclinic.org
Call 855. REFER. 123 or 855.733.3712
Lung Cancer
Results: 57 Doctors
PREV123NEXT
Results per page:
Dav... 阅读全帖 |
|
发帖数: 1 | 11 Cleveland Clinic
From Wikipedia, the free encyclopedia
Geography
Location 9500 Euclid Avenue, Cleveland, Ohio 44195, United States
Organization
Care system Private
Hospital type Academic
Affiliated university
Case Western Reserve University School of Medicine Cleveland Clinic Lerner
College of Medicine
Kent State University College of Podiatric Medicine
Services
Beds 1440
History
Founded 1921
Links
Website www.clevelandclinic.org
Lists Hospitals in the United States
The C... 阅读全帖 |
|
发帖数: 1 | 12 3727 W Wisconsin Ave
Milwaukee, WI 53208
Phone:(757) 652-2346
Summary
Dr. Jun Luo, MD is a family physician in Milwaukee, Wisconsin. He is
currently licensed to practice medicine in Wisconsin. He is affiliated with
Aurora Sinai Medical Center and Wheaton Franciscan Healthcare - St. Francis.
Education & Training
Eastern Virginia Medical SchoolEastern Virginia Medical SchoolResidency
Texas Tech University Health Sciences CenterTexas Tech University Health
Sciences CenterRes... 阅读全帖 |
|
p*******r
发帖数: 156 | 13 Postdoctoral positions available
A postdoctoral position is available in the Laboratory of Cellular and
Molecular Biology at the National Cancer Institute. A focus of current
studies is understanding the contribution of integrin adhesion complexes,
including focal adhesions and invadopodia, to the control of cancer cell
proliferation and survival. A class of proteins called the Arf GTPase-
activating proteins (Arf GAPs), which regulate the Ras-superfamily proteins
Arfs and integrin adhesions, ... 阅读全帖 |
|
p*******r
发帖数: 156 | 14 Postdoctoral positions available
A postdoctoral position is available in the Laboratory of Cellular and
Molecular Biology at the National Cancer Institute. A focus of current
studies is understanding the contribution of integrin adhesion complexes,
including focal adhesions and invadopodia, to the control of cancer cell
proliferation and survival. A class of proteins called the Arf GTPase-
activating proteins (Arf GAPs), which regulate the Ras-superfamily proteins
Arfs and integrin adhesions, ... 阅读全帖 |
|
f******I
发帖数: 769 | 15
really agree with above, it takes a long time to get a donor as far as
transplant is concerned, and if there is metastatic disease, often
transplant will not be considered,
not sure what you meant by tumor cells in blood vessels, not an expert on it
or anything else, but does the patient have cirrhosis and ascites? seems
most of hepatocellular carcinoma from either hep b or c is from chronic,
patient with cirrhosis will have congestion through diseased liver thus
blood flow filtering through li |
|
f******I
发帖数: 769 | 16
pancreatic cancer with metastatic disease in the lungs, just matter of time,
any chemo would be palliative only, i'd say looking into palliative care
and be comfortable and die in peace and dinigity, |
|
f******I
发帖数: 769 | 17
depends on cell type, adenocarcinoma, lymphoma, carcinoid, or leimyosarcoma,
also depends on if it's localized or metastatic, if localized, surgical
resection is always the treatment of choice, |
|
f******I
发帖数: 769 | 18
not much you can do with metastatic liver cancer, palliative care/hospice
maybe the best option |
|
f******I
发帖数: 769 | 19
metastatic cancer is not curable, no matter in china or in america, |
|
t*******n
发帖数: 4445 | 20 //blush 我也就算一业余爱好者。
查了一下文献,目前认为C255能增强化疗对肿瘤组织的抑制,但没有减轻症状和提高长期
存活时间的数据。如果其他药物不成问题的话,能否考虑不用C255（至少揪住医生问其
具体效用是什么，有多大可能）。
C255的北美生产厂家是这么说的:
"The effectiveness of Erbitux in combination with irinotecan is
based on objective response rates. Currently, no data are available that
demonstrate an improvement in disease-related symptoms or increased survival
with Erbitux in combination with irinotecan for the treatment of EGFR-
expressing,metastatic colorectal carcinoma."
http://www.bms.com/cgi-bin/anybi |
|
g***r
发帖数: 285 | 21 probably metastatic disease, can get a PET scan and see if there is
increased uptake, |
|
g***r
发帖数: 285 | 22
sometimes i feel ridiculous that people would believe and follow such
nonsense, then again, when people are sick and desparate, they will believe
anybody who says the disease can be "cured", i guess it's another form of
denial,
this not only happens back in china, but here in the states as well, had a
patient who was diagnosed with breast cancer, instead of seeking medical
help, she went off to some "holistic" medicine guy, 2 yrs later she came
back with metastatic disease in brain and liver, m |
|
l*****O
发帖数: 402 | 23 Sorry, i am not saying she definitely has metastasis. I assume 胃癌晚期 is
terminal stage IV. I guess I am wrong. Maybe according to the definition in
China, she's at stage III which is not metastatic yet. Obviously she
responded really well to chemo therapy but poorly did she tolerate it. Maybe
she should carry on the chemo but at the same time use chinese medicine to
control the side effects and decrease her discomfort from chemo. Just my 2
cents. The ultimate outcome of giving up conventional ca |
|
|
t****o
发帖数: 41 | 25 nodnod，当年检查结果是ER(++),PR(-),Her-2(++++)，这些说明什么哪？我妈说就是说
明她的基因不好，就是很容易长肿瘤的那种体质，是这样嘛？那诊断治疗过程中要注意
什么？
他们约了礼拜六做MRI。
doubt and that is the only suspected area, it is not unreasonable to
consider CT guided biopsy of lumbar spine.
only disease carry the best prognosis among all metastatic breast cancer,
you might expect 5 years and sometimes even longer. Treatment normally
involves bisphosphonate and hor |
|
g*****j
发帖数: 1211 | 26 想请问大家的问题包括以下：
1.这种情况预后会很差么？在网上搜了一下淋巴转移还是很影响预后的，但是不知道具
体到父亲这种情况，就是术后几年以后出现转移，发现得早，这样子的预后具体会有多
乐观还是悲观。
- I am not familiar enough with esophageal cancer. But overall,
metastasis to the lymph node is always bad news. In terms of prognosis,
whether or not metastasis is present matters more than the size of
metastatic tumor.
2.本来想让父母今年到美国来玩的。机票也都买好了，父亲现在还是很想来的。我们也
支持，到这边玩玩心情好一些，也许病情会有转机。（他们以前来过几次，每次也都还
玩得挺开心的）。但是不知道这二个月以后的复查要怎么样。医生说要做个CT看一下。
可是旅游保险好像都不保pre-existing conditions，所以想问问各位知不知道没有保
险做CT大约... 阅读全帖 |
|
f****o
发帖数: 2770 | 27 赶快去割掉啊
non-malignant割掉就没事的
你该不会已经metastatic stage了吧。。。
缺钙还是吃calcium + vitamin D吧 |
|
l*h
发帖数: 4124 | 28 I commented on your earlier message but oh man, this is killing me. When "医
生说很确定是颅咽管瘤", I thought they saw the typical presentations of it
because 颅咽管瘤 is so distinct on MRI scans. 颅咽管瘤 in children have
large cysts in >99% cases whereas infratentorial gliomas rarely show cystic
changes before radiation therapy. 颅咽管瘤 can encroach into the brainstem
but the epicenter is outside the brainstem.
Intracranial choriocarcinomas are very rare. But as HCG was significantly
elevated, it is a real possibil... 阅读全帖 |
|
f****o
发帖数: 2770 | 29 Herceptin
Herceptin (chemical name: trastuzumab) works against HER2-positive breast
cancers by blocking the ability of the cancer cells to receive chemical
signals that tell the cells to grow.
Tykerb
Tykerb (chemical name: lapatinib) works against HER2-positive breast cancers
by blocking certain proteins that can cause uncontrolled cell growth.
Avastin
Avastin (chemical name: bevacizumab) works by blocking the growth of new
blood vessels that cancer cells depend on to grow and function. On Nov. ... 阅读全帖 |
|
l*h
发帖数: 4124 | 30 "未找到原发灶"
was there any reason they were thought as metastatic? why cannot the "
pathologist" do a morphology description? multiple location itself does NOT
equal to metastasis. |
|
l*h
发帖数: 4124 | 31 1. i would have been completely honest with the pt from the beginning, to
explain the options at hand. quite few patients pursue painful treatment
without known benefits.
2. i would have ordered FDG-PET before surgery to look for metastasis.
regional met should be easily seen on CT or ultrasound before surgery. when
there is regional metastasis, there is almost certain also remote metastasis
. there is just some time lag. you cannot assume there is no. i truly don't
trust the so-called "spleen s... 阅读全帖 |
|
l*h
发帖数: 4124 | 32 since it's adenocarcinoma, it appears there was a justification to have
surgery, if it was to reduce tumor burden without much adverse effects on
lung functions.
the pleural invasion itself is sufficient to put it into stage IV, M1a. in
the US, about 40% non-small cell patients are at stage IV at the time of
diagnosis. the 5-yr survival is around 2%.
future treatment depends on various factors. generally speaking, it should
center on improving the quality of life unless the patient him/herself
s... 阅读全帖 |
|
h***f
发帖数: 162 | 33 this is probably a compression fracture. why was a ct not done? why was a
mri not done? ct and mri are definitive diagnostic tests for degenerative
pathologies of the spine.
if it is a compression fracture, one has to find the reason for it:
metastatic tumor? trauma? infectious lytic lesion? osteoporosis? calcium
dysregulation secondary to kidney or other metabolic disease? |
|
I****a
发帖数: 407 | 34 Debating one versus two primary is less important. The biggest enemy is two
spots in the bone. If money is not a huge issue, PET scan will be helpful.If
those two spots in bones are hot on PET, I would approach as if this is
metastatic stage 4 lung cancer. In this case, checking driver mutations such
as EGFR, ALK would be ultra important, targeted therapy really changed the
landscape of the treatment of stage 4 adenocarcinoma of
the lung.
Wish your mother best of the luck.
MeiGuoYongYi |
|
I****a
发帖数: 407 | 35 Debating one versus two primary is less important. The biggest enemy is two
spots in the bone. If money is not a huge issue, PET scan will be helpful.If
those two spots in bones are hot on PET, I would approach as if this is
metastatic stage 4 lung cancer. In this case, checking driver mutations such
as EGFR, ALK would be ultra important, targeted therapy really changed the
landscape of the treatment of stage 4 adenocarcinoma of
the lung.
Wish your mother best of the luck.
MeiGuoYongYi |
|
f****o
发帖数: 2770 | 36 afatinib是针对metastatic non small cell lung cancer
stage 1a吃这个干什么。。。 |
|
h***f
发帖数: 162 | 37 oncology is best at md anderson, memorial sloan kettering, dana farber.
maybe mayo clinic, johns hopkins.
definitely not stanford. if you must stay in california, then ucsf.
although i should add, the prognosis for metastatic ovarian cancer is not
good. |
|
c********p
发帖数: 322 | 38 The only useful thing in your post in bless. Please shut up and do not harm
this PT. Giving diagnosis without supporting proof equals to bullshit.
Lz need to provide more details before anyone can provide actual help. And
Lz should always trust your doctor before you have real proof that he did
something wrong. Mutual trust is the foundation of treatment. Without this,
I don't see why your doctor will refer you to any clinical trial.
Metastatic cancer is very hard if ever possible to treat. TPN ... 阅读全帖 |
|
c********p
发帖数: 322 | 39 The only useful thing in your post in bless. Please shut up and do not harm
this PT. Giving diagnosis without supporting proof equals to bullshit.
Lz need to provide more details before anyone can provide actual help. And
Lz should always trust your doctor before you have real proof that he did
something wrong. Mutual trust is the foundation of treatment. Without this,
I don't see why your doctor will refer you to any clinical trial.
Metastatic cancer is very hard if ever possible to treat. TPN ... 阅读全帖 |
|
l*h
发帖数: 4124 | 40 it is usually unprofessional for doctors to order drugs that are not
available in his own jurisdiction. remember, the vast majority of patients
are regular people. you are putting excessive burden on the patients and
their families if you ask the patients and families to find drugs that are
not available in his jurisdiction by themselves. the stress can be very
detrimental. in addition, the doctors don't know much about the drugs that
are not available in their own jurisdiction. in many countrie... 阅读全帖 |
|
az
发帖数: 16686 | 41 Family's life and death story and hope
http://today.msnbc.msn.com/id/42452205/ns/today-today_health/
Elisa and Nathan Bond’s life seemed perfect. Not long after their fairy-
tale wedding, they had a beautiful baby girl who was growing into a happy
toddler. Outside of a few extra pounds Elisa wanted to shed, she couldn’t
think of a single thing wrong with their lives.
But on Valentine’s Day, the fabric of their existence started to unravel.
Nathan, 38, learned he had Stage 3 colon cancer and only... 阅读全帖 |
|
|
p*******r
发帖数: 156 | 43 Postdoctoral positions available
A postdoctoral position is available in the Laboratory of Cellular and
Molecular Biology at the National Cancer Institute. A focus of current
studies is understanding the contribution of integrin adhesion complexes,
including focal adhesions and invadopodia, to the control of cancer cell
proliferation and survival. A class of proteins called the Arf GTPase-
activating proteins (Arf GAPs), which regulate the Ras-superfamily proteins
Arfs and integrin adhesions, ... 阅读全帖 |
|
S******i
发帖数: 71 | 44 【 以下文字转载自 Biology 讨论区 】
发信人: Suozucai (Zuzu), 信区: Biology
标 题: 南方医科大学中西医结合医院院长罗荣城教授严重剽窃他人论文，发表到diagnostic pathology.
发信站: BBS 未名空间站 (Wed Oct 7 21:14:58 2015, 美东)
南方医科大学中西医结合医院院长罗荣城教授严重剽窃他人论文，发表到diagnostic
pathology.
见过造假的，没见过这么造假的。。。。。。
论文公司的科学家学习学习吧，一本万利
The microRNA-1246 promotes metastasis in non-small cell lung cancer by
targeting cytoplasmic polyadenylation element-binding protein 4 (Weihua
Huang, Huifen Li, and Rongcheng Luo, 2015, Diagnostic Pathology
Journal)
MicroRNA-550a acts as a pr... 阅读全帖 |
|
L****a
发帖数: 572 | 45 2009:
Ben. Bernanke : Green Shoots
Obama : Glimmer of hopes
Roubini : Green shoots turn to brown weeds
Soros : The recovery will look like "an inverted square root sign"
James Rogers (April 2009) : I am short J.P. Morgan !
Geitner : ???
Nassim Taleb : The doctor has shown up and relieved the patient's symptoms
– and transformed the tumour into a metastatic tumour
2010:
Summers : We have a statistical recovery and human recession
..... ?? |
|
S*P
发帖数: 7575 | 46 有：
PROVENGE® (sipuleucel-T) is the first autologous cellular immunotherapy
to receive FDA approval for the treatment of asymptomatic or minimally
symptomatic metastatic castrate resistant prostate cancer. PROVENGE is
designed to induce an immune response against prostate cancer. |
|
S*********g
发帖数: 24893 | 47 IsoRay, Inc. (ISR)
-NYSE MKT Follow
3.30 Up 0.75(29.41%) 4:00PM EDT
After Hours : 3.27 Down 0.03 (0.91%) 4:31PM EDT - Nasdaq Real Time Price
Get the big picture on all your investments.
Sync your Yahoo portfolio now
Prev Close: 2.55
Open: 3.08
Bid: 3.23 x 1900
Ask: 3.24 x 2100
1y Target Est: 1.50
Beta: -2.56
Next Earnings Date: N/A
Day's Range: 2.93 - 3.77
52wk Range: 0.44 - 3.77
Volume: 111,809,792
Avg Vol (3m): 2,946,970
Market Cap: 126.74M
P/E (ttm): N/A... 阅读全帖 |
|
a****a
发帖数: 363 | 48 re!!
IsoRay, Inc. (ISR)
-NYSE MKT Follow
3.30 Up 0.75(29.41%) 4:00PM EDT
After Hours : 3.27 Down 0.03 (0.91%) 4:31PM EDT - Nasdaq Real Time Price
Get the big picture on all your investments.
Sync your Yahoo portfolio now
Prev Close: 2.55
Open: 3.08
Bid: 3.23 x 1900
Ask: 3.24 x 2100
1y Target Est: 1.50
Beta: -2.56
Next Earnings Date: N/A
Day's Range: 2.93 - 3.77
52wk Range: 0.44 - 3.77
Volume: 111,809,792
Avg Vol (3m): 2,946,970
Market Cap: 126.74M
P/E (ttm): ... 阅读全帖 |
|
n****8
发帖数: 294 | 49 Partial Clinical Hold on Ariad (ARIA) Study Lifted: Ariad’s investors
finally had something to cheer about with the FDA lifting a partial clinical
hold on the company’s phase II study of Iclusig in patients with
refractory metastatic and/or unresectable gastrointestinal stromal tumors.
New patients can now be enrolled in this study. Ariad also presented initial
data which indicate Iclusig’s anti-tumor activity in patients with
advanced GIST, particularly in patients with KIT exon 11 mutations. S... 阅读全帖 |
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