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全部话题 - 话题: malignent
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l*******n
发帖数: 68
1
Steve Jobs suffered from malignant pancreas neuroendocrine tumors which is
different from adenocarcinoma of the pancreas. The prognosis for malignant
pancreas neuroendocrine tumors is very good if the surgery is done early
enough. However, the adenocarcinoma of the pancreas has very poor prognosis
with extremely high mortality rate.
g***r
发帖数: 285
2
来自主题: Medicine版 - 我到底要不要做B超阿

depnds on the size of the polyp, in general, more than 20mm the chance is of
being malignant is high and should be removed,
polyp can be either a benign tumor like adenoma, or cholesterol deposit
which if breaks off might or might not cause inflammation/obstruction,
the malignant potential is quite low if the size is very small,
another interesting fact, though females are more prone to have gallbladder
disease, but during a study of autopsy the prevalence of gallbladder stones/
polyps are equa
c********e
发帖数: 496
3
whenever single nodule is found in the lungs, first thing the doc needs to
do is to compare it with other CXRs. Duration is very important.
Other points:
if the border is clear, if not, invasive.
if calcification around nodule, if yes, malignancy.
if lymphadenopathy, if yes, cancer.
if smoking history +, if family history +.
if there is any endocrinolgoical changes recently, if yes, pancoast tumor.
Many others.
If malignancy is more likely (80-90%), go for thoracotomy.
If not clear cut. do VA
c********e
发帖数: 496
4
来自主题: Medicine版 - 腮腺肿瘤求助
overall,
benign tumor: surgery only
malignancy: surgery plus radio
malignancy plus metastasis: surgery, radio, chemo.
follow up internal depends on the pathology report.
c********e
发帖数: 496
5
来自主题: Medicine版 - 甲状腺手术疑问
The physician is right, for hashimoto's during pregnancy, FT4 and TSH is the
most important parameter to tell whether YOU are OK, while the effect of
the disease on your baby is unpredictable.
50% of thyroid nodule found in the child/baby is malignant, the specificity
of FNA is 80%. Even if it is benign, 10-20% will be transformed into
malignancy in the future, so surgery is indicated.
For the thyroid surgery, it is not an easy one, not that hard either. The
reason is
1. the blood supply is supe
d******e
发帖数: 43
6
大家好!
我妈妈因为左边乳房不舒服,上周3月12日去做了Mammogram和ultrasound,结果出来了
,很不好,现在把结果贴出来,请各位XDJM帮忙看看:
“Color flow and real-time ultrasound were performed on the left breast.
Same day ultrasound perform for evalution of mammographic abnormality
demonstrades a 4.5x 2.4x4.2 cm lobulated solid mss with internal flow within
the left breast 2-3 o'clock.
Conclusion: ACR BI-RADS CATEGORY 4C: MODERATE SUSPICION FOR MALIGNANCY
The lobulated mass with flow in the left breast seen on mammogram and
ultrasound is at a moderated ... 阅读全帖
M****0
发帖数: 877
7
I am not a specialist in this field. I will try to answer some of your
questions.
Based on what you have described,this is most likely TB with supra infection
with other bacteria. Cultures for other bacteria should also be sent which
I believe they did.
Usually we determine the pleural effusion as exudate vs transudate.
Sanguineous purulent pleural effusion is highly indicated exudate, and
infection and malignancy both could cause this type of pleural effusion.
Therefore, ruling out malignancy i... 阅读全帖
M****0
发帖数: 877
8
来自主题: Medicine版 - 请帮忙看看爸爸胃部检查报告
My eyes are really hurting after reading all your reports.
I concern about "ulcerated mass" and the size of the mass. The path report
did not idenify malignant cells but as you know, the biopsy could miss the
cancer tissue. As mentioned in the comment of both endoscopy and CT scan
report, most likely this is cancer, and it causes symptoms. The next step
would be surgery: 1. could relieve symptoms; 2. could further clarify if
this is malignancy or not, and rule out local invasion and mets which w... 阅读全帖
h******g
发帖数: 65
9
来自主题: Medicine版 - 甲状腺问题
第一次在这里发贴, 不知道这样可以不
7月份b超是这样的,大家看看像不像恶性? 甲状腺双侧叶及峡部大小形体正常,被膜光
滑,腺体组织回声欠均匀,稍增粗,甲状腺左叶内见多处大小不等低等回声结节,较大
者位于腺体浅层,大小2.4*1.0cm,边界清晰。右叶中部深面似见0.7*0.4等回声结节,
边界欠清晰,CDFI上述结节周边可采集散在血流信号。左颌下见1.7*0.8淋巴结回声,左
颌下见2.1*0.9淋巴结回声。
8月份在国内另一家做的,想看一下那个大的变大没,没想到不同医院仪器不一样,没
法比较:甲状腺右叶1.79cm,峡部厚0.32cm,左叶厚1.89cm,实质回声增粗欠均,甲状腺
左叶可见中等回声结节,大小约2.36*1.15cm,边界尚清CDFI:期内可见血流信号显示,
左叶可见多个囊状回声及中强回声结节,较大者约1.1*1.0cm,甲状腺弥漫性改变。国内
这两个看着也不一样.
10月份回美国:
US THYROID OR NECK OR SOFT TISSUE
CLINICAL HISTORY: Palpable left thyroid nodule
TECHNIQUE: S... 阅读全帖
e***y
发帖数: 4307
10
来自主题: Medicine版 - 请问甲状腺癌在美国的治疗方法
i dont think blood test can provide differential diagnosis between benign vs
malignant unless medullary thyca is suspected. also biopsy should be
performed, however, depending on the location of the lesion it could be
difficult to biopsy given its size of 3mm. the patient could also choose to
watch and wait given the slow growing nature of thyca. i also saw an
article that says 70 percent of calcified thyroid lesions are malignant.

test
S*******t
发帖数: 3956
11
来自主题: NextGeneration版 - 卵巢手术归来
说的这么怕人。没有确定是恶性的。做了cancer screening,negative.先看ob,再看
specialist. specialist 说 malign 的可能性不大,因为可以动啊。最大可能是
benign 或者
border line malign.但是不管怎样,都要先把囊肿和卵巢全摘了,然后再分析,如果
是良性,就没
了。如果是恶性,所以生殖器官附件啥的都等摘(多吓人啊)。如果是border line,具
体情况具体分
析。
我问是不是一定要摘卵巢啊,他说一定要,以防万一。当然他给了另一个医生的电话,
让约了seek a
second opinion.
我觉得这个也太猛了吧。
s******e
发帖数: 493
12
Bless!
What is a rhabdoid tumor?

A rhabdoid tumor is a rare and highly malignant tumor of childhood, first
described in 1978. These tumors were initially considered an aggressive
variant of Wilms' tumor of the kidney, however, with newer diagnostic
techniques, these tumors are believed to represent a distinct entity. Since
that time, there have been fewer than 50 cases reported, although it is
likely that some cases previously identified as medulloblastoma or as
primitive neuroectodermal tumo... 阅读全帖
J*******0
发帖数: 108
13
今天有点时间,再多讲一点:肿瘤 (tumor)分良性(benign)和恶性(malignant).
Malignant tumor equals to cancer. Benign tumor is very common, and usually
is not fatal unless the tumor grows in unusual places. For example, benign
brain tumors could be fatal. This is because the space within skull is very
limited. When the benign tumor grows bigger and bigger, it will push other
brain parts. So its not the tumor itself kills patient but the "compression
effect" of the tumor causes the trouble.
t**********t
发帖数: 236
14
来自主题: NewYork版 - 9/2-9/6 Banff, Jasper
大致行程计划如下。欢迎建议。找个伴,男生女生都行。
9/2: Transportation
Arrive by air at Calgary in the evening. Get Rental Car. Drive to the town
of Banff.
9/3: Banff
Johnston Canyon
Moraine Lake
Lake Louise
Plain of Six Glaciers
Lake Anges
Crowfoot Glacier
Bow Pass and Peyto Lake Viewpoint
Stay overnight at motel in the area
9/4: Banff+Jasper
Mistaya Canyon
Saskatchewan Crossing and Viewpoint
Columbia Icefield
Sunwapta Falls
Athabasca Falls
Mount Edith Cavell
Stay overnight at motel in the area
9/5: Jasper
Municipalit... 阅读全帖
b******s
发帖数: 5329
15
达拉斯找游伴,8月下旬9月初10天左右游Glacier NP (USA), Banff, Yoho and Jasper
NP(CANADA, 需要加拿大签证)
大致计划,需要细化,可能调整。无法做到面面俱到,主要景点多些时间,一般的,就
到此一游啦。主要看:冰山、湖、动物。
希望成员:3-4人,身体健康。
住:大致两晚camping,一晚酒店这样穿插着。
交通:租车(full-size or SUV。 本人没驾驶过RV,更对山地RV没有把握)
活动:精典景点部分Hiking(根据距离,时间和体力);其他景点看看,发呆,照相;
泡温泉;boating..
吃:看着办。
装备:常规camping装备。不过,可能要带点厚衣服上冰山,另后半夜可能有点冷,所
以睡袋也不能太薄。
Day 1: DFW --> MSO (Missoula MT)--> west entrance, Go-to-the sun-->St Mary
Camping
Day 2: St Mary --> Many Glaciers, Hiking (Grinnell Glacier Trail or Iceberg
L... 阅读全帖
T*********s
发帖数: 20444
16
十天,疯了
第二天走完Grinnell Glacier Trail,所有人都废了。

达拉斯找游伴,8月下旬9月初10天左右游Glacier NP (USA), Banff, Yoho and Jasper
NP(CANADA, 需要加拿大签证)
大致计划,需要细化,可能调整。无法做到面面俱到,主要景点多些时间,一般的,就
到此一游啦。主要看:冰山、湖、动物。
希望成员:3-4人,身体健康。
住:大致两晚camping,一晚酒店这样穿插着。
交通:租车(full-size or SUV。 本人没驾驶过RV,更对山地RV没有把握)
活动:精典景点部分Hiking(根据距离,时间和体力);其他景点看看,发呆,照相;
泡温泉;boating..
吃:看着办。
装备:常规camping装备。不过,可能要带点厚衣服上冰山,另后半夜可能有点冷,所
以睡袋也不能太薄。
Day 1: DFW --> MSO (Missoula MT)--> west entrance, Go-to-the sun-->St Mary
Camping
Day 2: St Mary --> Many Glaciers, ... 阅读全帖
c**y
发帖数: 377
17
来自主题: Outdoors版 - Skin cancer---from WebMD
Skin Cancer
PDQ Treatment Summary for Health Professionals
Written for health care professionals, this review of the two primary skin
cancers (basal cell and squamous cell carcinoma) is thorough and up-to-date,
covering treatment for all stages of the diseases.
PDQ
Basal cell carcinoma is the most common form of skin cancer. The second most
common type of skin malignancy is squamous cell carcinoma. Although these 2
types of skin cancer are the most common of all malignancies, they account for
l
m*******0
发帖数: 27
18
Athabasca River rafting
Malign Lake – boat tour
Medicine Lake
Malign canyon – hiking 5 bridges
今天的主要活动是Athabasca River rafting (Heritage Run- 3 hrs) 。
这是俺们有生以来的第一次 漂流。所以挑了个最容易的,class 2。
即使这样,怕水的老公对这个活动仍颇有微词,偏偏天气又不好,报完到,
刚换好游泳衣,倾盆大雨就浇了下来。回头看看老公,已经是满脸舍命陪
君子的悲壮。两个帅帅的小导游,一个劲安慰大家不要担心,雨太大,
天气太冷的话他们会缩短行程的。
旅游公司的汽车把一群老老少少拉到了漂流的起点,雨已经停了,这就是
山里天气的特点。变幻莫测,后来的几天我们对此有了更深的体会。
换上wet suite,大家被分成两组,一组全是带小孩的,我们这一组是三对夫妇。
我们, 一对老夫妇从英国来,一对年轻夫妇从南边过来。我们的导游叫Steve,
让大家自己选择做哪里,年轻夫妇当仁不让的选了第一排,英国老夫妇选了第
二排,我们坐第三排,导游坐在最后。年轻夫
m*******0
发帖数: 27
19
下午去Malign Lake,事先定了5点钟的boat tour,就是为了去看看久负
盛名的Spirit Island. Malign Lake一整天都笼罩在乌云中,上了船,
四周一片烟雨凄迷。
导游小伙开始了讲解,语调既不跌荡起伏,也不抑扬顿挫,俺开始迷迷
糊糊的打起盹来。刚刚盹着,就被老公用胳膊纣叫醒了,老公说,快听
听,小伙子从名人八卦讲到野生动物保护,信息量很大啊。俺支着耳朵
勉强听了两句,听到他说某个名人,先嫁个老公大她20岁,后嫁个老公
小她20岁。不错啊,俺心里嘀咕一句,又见周公去了。一直到有人开门
到甲板上去,俺才被冷风吹醒。听到导游紧着告诉大家,甲板上最多只
能站8个人,不然船会翻的。扭头一看,老公已经跑到甲板上去了,赶紧
数数甲板上的人数,还好,只有6个。俺一直百思不解,这船也装了几十号
人,咋就这么脆弱呢?
到了Spirit Island,小的让人有些失望,看不出任何特色。也许是因为
天气不好的缘故,看不出那张让它盛名远扬的照片描绘的境界。导游给了
大家十分钟,沿着湖边的一个小路转一圈,拍两张照片,等天 好的时候,
再重游此地吧。
回到岸上已经是6:30pm了,开
h*********r
发帖数: 2844
20
Canadian Rockies 断腿游
(八)Jasper浅尝辄止
Jasper公园很大,trail也很多。我们时间有限,只能挑几个地方看看。一大早,我们
开车上了Jasper Town东面和16号路交接的一条公路。第一站是Maligne Canyon。这个
Canyon和前几天看到的瀑布峡谷比较象,基本上是沿途看河水冲刷形成的峡谷。河水还
是那种带点浑浊淡淡的绿色。峡谷上架着六座桥,从一号到六号桥要3.7公里,也可以
不走trail直接开车到二号桥或者五号桥边的parking lot。整条trail有些上上下下,
但总的比较容易,而且风景也很好,能看见激流,沿山而下的瀑布,地下暗河,溪涧中
的小岛,以及河中间冒出来的泉水。如果早点走,trail上没什么人,效果更好。我们
从一号到五号桥走了个来回,迷迷糊糊的忘了还有六号桥这段路没走,想想也就算了。
接着我们要开车到这段公路的尽头Maligne Lake 处。途中又看见一群big horn sheep
在马路中间散步,看见车过来,不但不怕,还把头凑上来盯着车里望,呵呵。接下来路
过一个景致不错的湖叫Medicine Lake,
h******c
发帖数: 2111
21
来自主题: Travel版 - Banff/Jasper9月初简略游记
和LD两人,在Banff和Jasper待了5天,简略游记如下
Day1:晚上11:30飞抵Calgary机场,过关约半小时,取车,住在离机场10分钟车程的
super8
Day2:在附近超市买东西后直接开往Jasper,住在Maligne Lodge,安顿好后到
Medicine Lake看日落,路上人烟稀少,遇到elk数只。
Day3:清晨6:30,去附近的PYRAMID LAKE拍日出,中午去MT EDITH CAVELL,Tonquin
Valley冰川和湖很美,遇到白马饮水于碧湖。晚上6点半再开回MALIGNE LAKE ROAD,拍
日落,再见elk数只。
Day4:清晨出发,走93A (和93平行,一过检票口200米右拐就是),路上有瀑布和安
静的湖泊。中午时分到达WILCOX PASS TRAIL,走了trail,很带劲儿,走到山顶,狂风
大作,冰雹袭击。附近有Columbia Ice field,朋友建议不去。下午到了BOW LAKE边上
的NUM-TI-JAH客栈,很美的地方,走了TRAIL。继续走,晚上住在Lake Louise Inn
Day5:早上去LAKE M
f******g
发帖数: 1697
22
☆─────────────────────────────────────☆
bachelor1031 (海天飞鸿) 于 h 提到:
加拿大落基山区精彩一周游,详细攻略+100张照片
更多照片请见:
http://goho80.spaces.live.com/
准备工作:
签证和身份问题:有美国签证签加拿大非常简单,也不需要面签,可以把材料寄过去签
。我在美国还是学生签证,已毕业,在实习,OPT F1,美国签证过期,有合法I-20,很
顺利拿到加拿大签证。注意:有合法I-20表格的人,即使美国签证过期,去加拿大,墨
西哥,加勒比地区30天以内,不需要美国签证依然可以回美国(注意:要享受这种政策
上等于没有离开过美国的待遇,要保存原始I-94表,出关的时候不要被收走)。在实习
的同学需要准备工卡和工作证明信。OPT期间可以大胆放心旅行。我回来从5号高速公路
入美国境,非常顺利,没有问我要OPT的工作证明信,只问我在哪儿工作就过了。工卡
也不看。整个过程不到一分钟。没有换I-94。等于说我们并没有离开过美国。
天气:天气是决定旅程满足与否的重要因素。8月17号到23号,落基山区... 阅读全帖
t**********t
发帖数: 236
23
来自主题: Travel版 - 9/2-9/6 Banff, Jasper找伴
大致行程计划如下。欢迎建议。找伴,男生女生都行。
9/2: Transportation
Arrive by air at Calgary in the evening. Get Rental Car. Drive to the town
of Banff.
9/3: Banff
Johnston Canyon
Moraine Lake
Lake Louise
Plain of Six Glaciers
Lake Anges
Crowfoot Glacier
Bow Pass and Peyto Lake Viewpoint
Stay overnight at motel in the area
9/4: Banff+Jasper
Mistaya Canyon
Saskatchewan Crossing and Viewpoint
Columbia Icefield
Sunwapta Falls
Athabasca Falls
Mount Edith Cavell
Stay overnight at motel in the area
9/5: Jasper
Municipality... 阅读全帖
t****z
发帖数: 8931
24
想起来了
去maligne lake
先有太阳的,
走了一会儿忽然乌云密布
下起大雪
我们继续开
前面有4条车印
雪越下越大
前面一辆车掉头了
我们跟着剩下2道车辙开
开了10分钟
那两道车辙突然消失的无影无踪
偶们就很奇怪,也很害怕
大雪弥漫
偶们商量一下
决定掉头
这时路边林子里钻出来一头狼
一个人拖着大尾巴在路上走
我们就慢慢后面跟着
跟了大概有一迈
狼跑到坡下面树林里面去了
这时太阳又出来了
路上雪也化了
偶们又掉头开往maligne lake
R**i
发帖数: 7994
25
来自主题: Travel版 - Canadian Rockies (一)Infomations
此次行程玩的时间一共3天半,只选取最经典的一些经典
POI visited on this trip:
Banff National Park:
Banff Gondola
Banff upper hot spring
Bow Vally Parkway (1A)
Lake Louise
Lake Moraine
Larch Valley
Agnes Tea House
Yoho National Park:
Emerald Lake
Lake O’Hara
Opabin Plateau Circuit
Shoreline Trail
Bow Lake
Peyto Lake/Peyto Glacier
Jasper National Park
Athabasca Glacier
Athabasca Fall
93A:Meeting of the rivers
Mt Edith Cavell
Jasper
Maligne Canyon
Medicine Lake
Maligne Lake
Spirit Island
Miette Hot Spring
h******v
发帖数: 1826
26
来自主题: Travel版 - [八月活动]去Banff玩了
我们去加拿大rocky mountains的Banff玩了.
先在Edmonton去了Elk Island National Park.因为到傍晚了,看到了一大群bison.
后来去Jasper:
Maligne Lake够大,漂亮;
Mt. Edith Cavell ,推荐!
Maligne Canyon, 走trail,小累。
Columbia Icefield的tour,我们赶上了5:30pm倒数地第二班车,这个时间去真是太好
了,只有10个人!
再后来去了Banff:
Sulfur mountain, 坐缆车上去,7分钟,走下来,1个半小时。这是我们走的最长的一
路,还全程往下冲,结果我和LD第二天都腿疼,孩子们则一点事都没有。这一路还是挺
有趣的,拐来拐去的,时不时从缆车下穿过,经常能鸟看一眼Banff全城,树上蓝鸟叫
红松鼠跳。。。
Bow river的raft tour,很平缓,很放松,有点象武夷山的竹筏漂流tour的感觉。
下了船来,小朋友们又在岸边扔了两个小时石头,其乐无穷,似乎比看山看湖有思多了!
Lake Louise, 很漂亮,人很多,湖畔的Fairmont H... 阅读全帖
p*****2
发帖数: 1542
27
来自主题: Travel版 - banff, jasper&yoho初步感受
去lake maligne路上路过的lake medicine挺美的,lake maligne是比较安静,尤其是
环湖那个小trail
lake o'hara是那边一带最美的地方,就去了opabin和oasa两条路就特别特别美了,但
都得靠走。估计那个大环的alpine circut更美吧,只是去的时候太早那条路有雪不推
荐走。emerald要等快日落的时候,湖水很安静。
lake louise就是生活方便吧,没走six galcier那个trail,就走了lake agnes那个,
再上了little beehive去俯瞰了lake louise,就像城堡酒店的游泳池一样,看bow
valley的景色也很壮观。
如果选肯定是Lake Moraine >> lake Louise,去划了一小时船太美了,如果有时间一
定要走一下larch valley那个trail,上面景色很赞!

alaska
看到
b******s
发帖数: 5329
28
Dallas找游伴,8月下旬9月初10天左右游Glacier NP (USA), Banff, Yoho and Jasper
NP(CANADA, 需要加拿大签证)
大致计划,需要细化,可能调整。无法做到面面俱到,主要景点多些时间,一般的,就
到此一游啦。主要看:冰山、湖、动物。
希望成员:3-4人,身体健康。
住:大致两晚camping,一晚酒店这样穿插着。
交通:租车(full-size or SUV。 本人没驾驶过RV,更对山地RV没有把握)
活动:精典景点部分Hiking(根据距离,时间和体力);其他景点看看,发呆,照相;
泡温泉;boating..
吃:看着办。
装备:常规camping装备。不过,可能要带点厚衣服上冰山,另后半夜可能有点冷,所
以睡袋也不能太薄。
Day 1: DFW --> MSO (Missoula MT)--> west entrance, Go-to-the sun-->St Mary
Camping
Day 2: St Mary --> Many Glaciers, Hiking (Grinnell Glacier Trail or Iceber... 阅读全帖
b***n
发帖数: 13455
29
来自主题: Travel版 - Banff, Jasper 行程 finalized
7月底8月初.有行程重合的欢迎联系
Day 1: Fly to YYC, stay in Sheraton
Day 2: Drive to Banff, Cascade Pond, Lake Minnewanka, Two Jack Lake, Sulphur
Mountain, Upper Hot Springs, stay in Best Western
Day 3: Bow Falls, Tunnel Mountain Loop, Vermilion Lake, Bow Valley Pkwy,
Hillside Meadow Johnson Canyon, Castle Mountain, stay in Best Western
Day 4: Lake Louise, Moraine Lake, Fairview Lookout, Yohoo, stay in Fairmont
Banff Springs
Day 5: Natural Bridge, Emerald Lake, Icefield Parkway, Hector Lake, Crowfoot
Glacier,... 阅读全帖
b***n
发帖数: 13455
30
来自主题: Travel版 - 加拿大Banff, Jasper 8日游记(4)
动物
一路上像松鼠这样的小动物遇到很多, 而且是近距离接触。 在去Edith Glacier的路
上遇到了一只熊妈妈带着两个熊宝宝在路边觅食。 一溜车都停在路边狂拍, 但都不敢
走太近, 生怕激怒了熊妈妈, 把我的胖儿子抓去给熊宝宝做晚餐就太悲剧了。
在Maligne Canyon两次遇到鹿群。 鹿子很敏感, 一举起相机它就警觉的抬起头, 随
即退后两步。 在去Maligne Lake的路上遇到的山羊则是毫不害怕, 还把头伸进车里来
东张西望, 反而把领导吓得尖叫, 而两个孩子则兴奋的大叫:“妈妈, 快照相!妈
妈, 快照相!”
b***n
发帖数: 13455
31
来自主题: Travel版 - 加拿大Banff, Jasper 8日游记(5)
行程
第一天中午从PHX 直飞YYC,住Four Points by Sheraton at Calgary Airport. 在大
统华随便买了些吃。
第二天前往Banff, 先去Cascade Pond, 然后是Lake Minnewanka, Two Jack Lake,
Johnson Lake, 围着Johnson Lake走了一圈, 然后是Tunnel Mountain, Gondola上
Sulphur Mountain, Hot Springs, 晚上歇Best Western.
第三天走Bow Valley Parkway, Johnason Canyon, 一直走到Upper Springs. 然后去
Verzillion Lakes, 结果发现这是此行最坑爹的景点,完全是浪费时间。惺惺然的回到
Banff 镇上,参观了Cascade Garden, Bow Falls, 走了镇附近的两个trail, 继续住
Best Western.
第四天一早直奔Lake Moraine. hiking. 中午到Fairmont Lake Louise 去check in,
结... 阅读全帖
d****a
发帖数: 445
32
请问一下,九月初去Banff,晚上5点半到calgary机场,计划当天晚上住在路易斯湖,
开过去来得急吗?
我查google是两个小时的车程,但看攻略上从Banff镇过去就要两个小时。是不是把去
johnston canyon的时间也算上了?另外多问一句,这个峡谷是不是不好玩,我看有人
说比较坑。我们假期一共就三天,还要去Jasper,是不是这个峡谷就可以省了?
有没有谁能热心推荐一些必玩的景点?maligne lake的游船值得一坐吗?maligne峡谷据
说不错。还有那个哥伦比亚冰川,是坐车上去比较好玩,还是在底下hiking?抑或都应
该尝试?
多谢!
y***x
发帖数: 162
33
来自主题: Travel版 - banff 4天怎么安排?
四天去jasper紧一点,也不是不可能
1 banff镇,johnston canyon, lake louise, moraine lake
2 yoho (takakkaw falls, emerald lake), 回头往jasper走, bow lake, peyto lake
, columnbia icefield,中间找个地方住下
3 继续往jasper, athabasca falls, sunwapta falls, 天使冰川,jasper周围几个湖
4 maligne canyon, maligne lake
x**s
发帖数: 822
34
来自主题: Fashion版 - 给来美国下巴长痘痘的mm
慎重哈,看了这个E-mail很吓人那
LISTEN UP FOLKS:
This is something that we should all take seriously – just had a recent
test myself that sent shivers up my spine – or near by – Even doctors are
now saying that there is value in trying “LEMON”
So, a tablespoon of "real lemon" (the concentrate in a bottle) in a glass of
water every morning.
What can it hurt?
A must-read-The surprising benefits of lemon!
I remain perplexed!
================================
Institute of Health Sciences, 819 N. L.L.C. Charles S... 阅读全帖
s****y
发帖数: 364
35
捐献角膜是义举和善事,我开始就同意,也没人否认.是否称得上神圣就是另一回事.但从
医学角度讨论一下是否有副作用也谈不上亵渎(可能除了在姚粉的眼里).就连神也是可
以自由讨论是否存在的不是吗.何况我的讨论不涉及姚贝娜, 只是针对医生的决定.
如果接受器官移植的人用药导致不排斥异体器官,也就会同样的允许了可能不小心移植
来的肿瘤细胞的繁殖.
角膜没有血管,但周围的边缘limbus是可能出现转移的癌症的.而手术中不太可能保证一
个潜在肿瘤细胞的污染都没有吧.
http://www.ncbi.nlm.nih.gov/pubmed/23928951
也发生过癌症患者去世后捐献角膜,后来病理检查剩余组织发现有癌变,导致接受角膜移
植的患者要接受再次角膜移植, 来替换掉第一次移植的有癌变可能的角膜.
http://www.ncbi.nlm.nih.gov/pubmed/18997546
这个文章的第一作者就是深圳的Yao, Xiaoming,很可能就是为姚贝娜摘除角膜的医生姚
晓明.他自己在文章里建议为避免移植角膜导致转移癌症到受者,移植角膜术前应做切片
病理检查. 所以希望他该做的检查都做了吧.接... 阅读全帖
D*****r
发帖数: 6791
36
来自主题: TrustInJesus版 - For the Liberty of Unlicenc'd Printing
A SPEECH OF Mr. JOHN MILTON
For the Liberty of VNLICENC'D PRINTING,
To the PARLAMENT of ENGLAND.
______________________________________________________________
This is true Liberty when free born men
Having to advise the public may speak free,
Which he who can, and will, deserv's high praise,
Who neither can nor will, may hold his peace;
What can be juster in a State then this?
... 阅读全帖
T**********e
发帖数: 29576
37
下面这篇文章对Jobs的胰腺内分泌癌治疗总结的不错,看来死的有点冤。
1. 10-2003 确诊,07-2004终于手术切除,期间Jobs一直在试自己选的diet疗法。扫描发现癌变在扩大才动了手术,这段时间癌转移的多少不可知,但肯定越拖转移的越多。
2.手术后没化疗和放疗。Jobs 2005年演讲说这表明病情乐观,不知是哪个庸医给他灌输的。2004年手术是大面积切除,部分胰腺和胃和小肠,胆和胆管都切除,目的是要消除扩散,但不系统化疗和放疗怎么能最大程度减少扩散威胁?哪个外科大夫这么信自己的手艺?
3.2009年换肝,这在扩散性癌治疗是有争议的,因为换肝后压制免疫反应有可能促进别处癌的生长。也有可能当时肝已经不行了没办法。
这种癌正常治疗大多数可活10年以上,Jobs真该到东岸Hopkins或Harvard找个靠谱的大夫。
Jobs’s Unorthodox Treatment
Some of Apple trailblazer Steve Jobs’s cancer treatment choices, from
alternative therapies to a liver tra... 阅读全帖
h********n
发帖数: 4079
38
来自主题: Biology版 - 求建议: tumor suppressor 基因
各位回帖说得真好啊. 我也乱说一些我的做法.
1. what is the promoter? if you know the promoter, you can guess whether it
is a tissue specific gene.
2. what cell type in pancreas express this gene, epithelial or other?
immuno staining should answer this question.
3. select cell lines based on answer to question 1 and 2
4. take highly malignant cancer cell lines, overexpress this gene by
transient transfection, cell viability assay, tumorigenecity (in vitro and
in vivo) assay and invasion assay should be used. Growth... 阅读全帖
t**m
发帖数: 158
39
http://en.wikipedia.org/wiki/Transmissible_cancer
wiki上说野生环境下目前知道三种可"传染"的癌症
1. Devil facial tumour disease (DFTD)
就是刚才说的熊熊的那个

2. Canine transmissible venereal tumor (CTVT) is sexually transmitted cancer
in dogs. It was experimentally transplanted between dogs in 1876 by M. A.
Novinsky (1841–1914). A single malignant clone of CTVT cells has colonized
dogs worldwide, representing the oldest known malignant cell line in
continuous propagation.
这个可能和lz说的最接近了...
3. Contagious reticulum ce... 阅读全帖
m**********3
发帖数: 706
40
来自主题: Biology版 - 再说说关于刘廷析的二三事
He received his postdoc training from Harvard. And he had some decent
publications. His level should be equal to some AP in the US.
Liu TX, Becker MW, Jelinek J, Wu HS, Deng M, Hsu K, Bloomfield C, Stone R,
Issa J-P, Erba HP, Clarke MF, Look AT. (2006) Deletion del(5q) and
epigenetic suppression of alpha-catenin (CTNNA1) in myeloid malignancy.
Nature Medicine.
Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea
AD, Look AT. (2003) Disruption of FANCD2 function causes con... 阅读全帖
h********n
发帖数: 4079
41
来自主题: Biology版 - 肿瘤生物学研究的逻辑?
some of cancer cells have chromosome instability, including aneuploidy. The
ratio of aneuploid cancer cells in all cancer cells depends on many factors
, such as cancer type, malignancy, etc.
This is a very complex topic. Genomic instability including aneuploidy is
usually harmful to cells including cancer cells. But it does give more
diversity so a small percent of cell might outgrow and become malignant. I
have a manuscript submitted about this topic, whose results are supprising
to us. B... 阅读全帖
h********n
发帖数: 4079
42
来自主题: Biology版 - 肿瘤生物学研究的逻辑?
some of cancer cells have chromosome instability, including aneuploidy. The
ratio of aneuploid cancer cells in all cancer cells depends on many factors
, such as cancer type, malignancy, etc.
This is a very complex topic. Genomic instability including aneuploidy is
usually harmful to cells including cancer cells. But it does give more
diversity so a small percent of cell might outgrow and become malignant. I
have a manuscript submitted about this topic, whose results are supprising
to us. B... 阅读全帖
g****1
发帖数: 261
43
Good job!
http://www.futureoftech.msnbc.msn.com/technology/futureoftech/1
An artificial “brain” built by a 17-year-old whiz kid from Florida is able
to accurately assess tissue samples for signs of breast cancer, providing
more confidence to a minimally invasive procedure.
The cloud-based neural network took top prize in this year’s Google Science
Fair.
“I taught the computer how to diagnose breast cancer,” Brittany Wenger,
the Lakewood Ranch resident, told me today.
“And this is really importan... 阅读全帖
S**********e
发帖数: 1789
44
来自主题: Biology版 - 【想海归求建议】
给你看看我们系刚进来的助理教授
Vanderbilt University School of Medicine
Fingleton, Barbara Mary , Ph.D. Assistant Professor of Cancer Biology
Publications

Barrett, CW, Fingleton, B, Williams, A, Ning, W, Fischer, MA, Washington, MK
, Chaturvedi, R, Wilson, KT, Hiebert, SW, Williams, CS. MTGR1 is required
for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model.
Cancer Res, 71(4), 1302-12, 2011.
Koon, HB, Fingleton, B, Lee, JY, Geyer, JT, Cesarman, E, Parise, RA, Egorin,
MJ, Dezube, BJ... 阅读全帖
l*******1
发帖数: 38
45
other malignancy defects->genomic instability
or
genomic instability -> malignancy?
b*******1
发帖数: 16
46
岗位一:吴虹课题组博士后工作人员 (2名)
主要职责:
1)独立开展科研工作,动手进行体内外实验;
2)协助PI负责实验室研究课题的设计和开展;
3)参与科研基金撰写;
4)协助培养研究生。
招聘条件:
1)品学兼优,身体健康,年龄在40岁以下;
2)近年来在国内外获得分子生物学、细胞生物学、肿瘤遗传学、药理学等相关专业博
士学位;
3)至少具备一项以下领域内的工作经验和文献发表:
a. 独立运用细胞和动物模型进行肿瘤药物的机理研究
b. 在分子生物学和细胞生物学领域有深厚的知识背景;
c. 在蛋白质分析、核酸分析和细胞生长分析等相关技术方面有丰富的经验;
d. 对治疗癌症的药物疗效和安全性评价方面有强烈的兴趣和研究背景 ;
4)有较强的团队合作精神,沟通协调能力强,动手能力强,工作细心,积极主动,能
持之以恒;
聘用待遇:
本职位将为你提供在生物学领域极具竞争力和创造性的工作机会。博士后工作人员薪酬
标准按照北京大学生命科学院和北大-清华生命科学中心相应规定及个人工作经验及能
力确定。
联系方式:
有意者请将本人应聘材料电子文档发至以下联络方式(请在应聘材料及邮件主题上注明
:姓名 ... 阅读全帖
r******g
发帖数: 600
47
不好意思,我问的问题有点儿歧义。
我们可以这么分析
Rituximab 治疗 B cell lymphoma 基本上是神药了~ 这么多年来,genetech挣了不少
钱。 其实机制很简单,就是把病人体内 normal和malignant的B cell全部杀光,
targeting CD20.
Car T 目前最好的trial是 target CD19, 跟CD20机制类似,说到底就是 换汤不换药,
用transduced engineered T cell把CD19+的normal 和malignant B 细胞一起杀掉。目
前 clinical trial主要用于 B cell leukemia.
其实rituximab治疗B cell leukemia的效果很好,你去查一下clinical trial的结果,
naive patient 90% 的有效率~ 但是,pharma也没有很积极的把rituxan推向clinical
trial。原因是“rituxan现在很能挣钱,就让它继续挣,专利15年过期,再用于
leukemia挣钱” 或者“用car 挣钱?“
Car T这几年 副作... 阅读全帖
h********n
发帖数: 4079
48
来自主题: Biology版 - 研究HPV还有前途吗?
Now one of the big challenge is the existing high risk HPV-infected people.
There is no drug to kill HPV so people have to wait for pre-malignancy and/
or malignancy caused by HPV.
t****o
发帖数: 342
49
来自主题: MedicalCareer版 - String的im面经8-15
Woodhull的PD太搞笑了!年轻没家庭压力的小印在完成huge workload这一点上绝对更
有竞争力,这些繁忙program的PD肯定喜欢24/7干活不倒的人。
Howard 三个同时面试太差劲了,难以想象会有这种事情。
看来没有最malignant,只有更malignant。
l*******8
发帖数: 1745
50
来自主题: MedicalCareer版 - 面试记 NYC-Bronx Lebanon
这个医院很malignant,有好的选择就别来了,Lincoln 也很malignant,说老实话,如果
有更好的选择,就别来这里了。
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