w****y
发帖数: 2952 | 1 有啊.他只列了几篇.
Jun Lu, Shangqin Guo, Benjamin L. Ebert, Hao Zhang, Xiao Peng, Jocelyn Bosco
, Jennifer Pretz, Rita Schlanger, Judy H. Wang, Raymond H. Mak, David M.
Dombkowski, Frederic I. Preffer, David T. Scadden and Todd R. Golub.
microRNA-mediated control of of cell fate in megakaryocyte-erythrocyte
progenitors. Developmental Cell, 14(6):843-53, 2008
Zejuan Li, Jun Lu (co-first author), Miao Sun, Shuangli Mi, Hao Zhang, Roger
T. Luo, Zhijian Qian, Mary Beth Neilly, Yungui Wang, Jie Jin, Yanming ... 阅读全帖 |
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K**********n
发帖数: 1197 | 2
跟这帮自称理科的文科生物wsn实在纠缠不清楚。给丫们上点洋大人自己的说法吧，而
且都是学术圈的，已有reference一堆，其中一份是著名的兰德公司的报告。
另外，美国和澳洲已立法限制使用脑波扫描仪，拿脑波扫描仪扫本国公民已是联邦法的
重罪。不过这个比较难的是你无法证实谁接收了你的脑信号。所以立了法跟没立一个样。
Remote Mind Control Technology
Reprinted from SECRET AND SUPPRESSED: BANNED IDEAS AND HIDDEN
HISTORY, edited by Jim Keith, $12.95, available from
1-800-680-INET.
There had been an ongoing controversy over health effects of electromagnetic
fields (EMF) for years (e.g., extremely low frequency radiation and the
Navy's Project Sea... 阅读全帖 |
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u**c
发帖数: 17972 | 3 Search Results
News
USS Ronald Reagan Sailors to Refile Suit For Fukushima Radiation Poisoning
San Diego Free Press 21 hours ago
By Brandon Baker / EcoNews After U.S. Navy sailors on the USS ... in Japan
for four days, many returned to the U.S. with thyroid cancer, ...
More than 70 Radiation-Stricken U.S. Sailors Sue Fukushima Plant Operator
AllGov- 2 hours ago
Fukushima Meltdown?
American Free Press- 5 hours ago
More news for cancer us sailor fukushima
US sailors claim cancer from helping at F... 阅读全帖 |
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d*b
发帖数: 21830 | 4 也是徐州人，小时候还跟爹一起在东北闯荡过一段时间。当年行骗的借口也是得了白血
病。
苏北的问题其实跟台湾的问题的根源是同一个：丫的普遍认为人能骗你们，是因为人比
你聪明，苏北这个地方的人从老到小根本没有道德不道德那种概念。外国语学校的学生
水平很高么？英语倒是不错，但学习上除了英语还真没看出有什么出跳的地方。
这种集中化的外国语学校为什么出现在相对不发达的常州本身就是个疑问。而且医学上
根本没有大面积高比例的induced leukemia的报道，要知道leukemia不是中毒，需要
DNA double strand break后才能发生。是基因突变引起的。
反正，徐州人，常州人，都得白血病死光了最好。 |
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发帖数: 1 | 5 Yarmouth Port, Massachusetts
From Wikipedia, the free encyclopedia
Yarmouth Port, Massachusetts
Census-designated place
Boardwalk at Bass Hole
Location in Barnstable County and the state ofMassachusetts.
Coordinates: 41°42′17″N 70°13′15″WCoordinates: 41°42′17″N 70°13′
15″W
Country United States
State Massachusetts
County Barnstable
Town Yarmouth
Area
• Total 6.47 sq mi (16.76 km2)
• Land 6.04 sq mi (15.65 km2)
• Water 0.43 sq mi (1.11 km2)
Elevation 52 f... 阅读全帖 |
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T******o
发帖数: 136 | 6 none of u folks hit the real question here: the real question is NOT what
percent of leukemia kids had luxury upgrades in their homes, BUT what
percent of homes with a luxury upgrade had a leukemia kid. compare that
number to the homes without a luxury upgrade |
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发帖数: 1 | 7 在网上发现了一个圣诞节商店，商店的建筑很有特色，而且遍布全美国，大概有70多个
店铺，以后大家买圣诞节用品可以去那里，似乎各州都有。我们这里和麻州的地址是：
CHRISTMAS TREE SHOP AUGUSTA, GA, 239 ROBERT C. DANIEL JR. PARKWAY,
AUGUSTA EXCHANGE, AUGUSTA, GA 30909, 706.738.0570, CHRISTMAS TREE SHOP
, MAGNOLIA PARK, 1117 WOODRUFF ROAD, GREENVILLE, SC 29607. 864. 297.
3667
CHRISTMAS TREE SHOPS NATICK, 1298 WORCESTER ST. ROUTE 9, SHERWOOD
PLAZA, NATICK, MA 01760, 508.655.9800
CHRISTMAS TREE SHOPS SOMERVILLE, 177 MIDDLESEX AVENUE, ASSEMBLY SQUARE
... 阅读全帖 |
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S*******n
发帖数: 10009 | 8 解决了？
再说了这么吵的车能天天开吗？
http://www.cancer.org/cancer/cancercauses/othercarcinogens/poll
Lung cancer
Lung cancer is the major cancer thought to be linked to diesel exhaust.
Several studies of workers exposed to diesel exhaust have shown small but
significant increases in risk of lung cancer. Men with the heaviest and most
prolonged exposures, such as railroad workers, heavy equipment operators,
miners, and truck drivers, have been found to have higher lung cancer death
rates than unexposed workers. A... 阅读全帖 |
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f**s
发帖数: 18 | 9 Based on the numbers you gave, your father is very near an acute leukemia.
MDS is a very complicated disease, even experts in WHO could not reach a
consensus on the classification. Go to talk with a hematologist/oncologist
first before you borrow bone marrow smear from China. If you want a good
guideline for therapy, bone marrow smear may not be enough. Unfortunately,
neither MDS nor transformed acute leukemia has good response to even most
advanced therapy.
原始粒细胞 myeloblast
早幼粒细胞 promyelocyte
中 |
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f******I
发帖数: 769 | 10
myelodysplastic syndrome with refractory anemia is often primary due to
chromosomal abnormalities, rarely it's secondary and when it is, it's often
from chemo or radiation treatment from previous leukemia/lymphoma,
the only cure i know of would be bone marrow transplant with a matched HLA
donor, it has risk to progress to acute leukemia, and is often refractory to
commonly used chemos,
sounds like he is also hypercoagulable, |
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w**********9
发帖数: 242 | 11 for chronic myeloid leukemia, most cases can be cured with STI-571 (Gleevec).
for acute granulocyte leukemia, it is curable with vitamine A.
others will be treated best with bone marrow transplantation |
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m*********t
发帖数: 858 | 12 恩了解。。。。。看来是很不乐观啊。。。。非常非常感谢您提供这么多信息。有时候
在想要是当初听她的话学医就好了，现在也不会什么都不知道，再次感谢！
first I'd like to let you know my level of involvement with leukemia
patients so you can think about whom else you should seek advice from.
i am not involved in bone marrow transplant or general management of
leukemia patients. i am involved in the management of patients with brain /
spinal cord infiltration, and other patients requiring neurological care.
in general, the remission rates are very high for adult ALL patient |
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c**i
发帖数: 6973 | 13 Peter Landers, New Breast Cancer Drug Found Deep in the Sea. Wall Street
Journal, Jan. 4, 2010.
http://online.wsj.com/article/SB1000142405274870411150457605977
("A study found it [Halaven] extended the life of patients with advanced
breast cancer by about two-and-1/2 months, to 13 months")
My comment:
(a) Eisai Co., Ltd. エーザイ株式会社
(a public company; headquarters Tokyo; established in 1941 by Toyoji NAITO
内藤 豊次 as Nohon Eisai Co., Ltd. 日本衛材（衛生材料の略。具体的には絆創膏
や包帯の事))
ja.wikipedia.org
(b) eribulin
htt... 阅读全帖 |
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T****O
发帖数: 407 | 14 A reminder: Gleevac is for a specific type of chronic myeloid leukemia (CML)
. It's of no use for other types of leukemia. |
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l*****y
发帖数: 5737 | 17 ☆─────────────────────────────────────☆
jck (浮萍妈妈) 于 (Wed Feb 20 13:59:02 2008) 提到:
我父亲在被诊断为Myelodysplastic syndrome。现在正在用Amifostine，也考虑用
vidaza。看了网上文章，Amifostine好象还实验阶段。我们对Amifostine的疗效怀疑。
我父身体很弱，反应很大。我想把他的骨髓细胞检验报告翻译到英文好在美找专家问问
。可是我用了好几个小时才翻了几个字，还不确定。请各位能者帮着翻一下，哪怕一个
词也好。谢谢了！
原始粒细胞 15 0-1.0
早幼粒细胞 2 0-2.5
中性中幼粒细胞 18.5 3.2-13.5
中性晚幼粒细胞 17 5.0-20.0
中性杆状核粒细胞 21 8.5-25.0
中性分叶核粒细胞 5 6.1-20.0
嗜酸性中幼幼粒细胞 0-1.1
嗜酸性晚幼粒细胞... 阅读全帖 |
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f****o
发帖数: 2770 | 18 chronic lymphocytic leukemia does not require treatment
until it become acute leukemia...
monitor for symptoms such as night sweat, fever, weight loss
should be followed up with a hematologist regularly |
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h**********8
发帖数: 650 | 19 Mutagenesis lead to around 20 % M2 Leukemia
But I do not think stem cell can easily cure Leukemia since cancer cell
proliferate too fast.....
？！ |
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t**h
发帖数: 91 | 20 Save 4- year-old Leukemia girl，Zhangyuxin , whose father is migrant worker
in China ,Yunnan province ,has worked as housing estate Security.her
father
earns 1500RMB per month ,raise four people family ,now the poor family hit
Young cute girl by Leukemia in end of Nov.2011
Please save the girl!
donation page （in Simple Chinese）
https://love.alipay.com/donate/enter.htm?name=2012011617092041001
老天，终于搞定照片了，小佩服一下自己！ |
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t*******r
发帖数: 22634 | 23 EQ is essential for facing life vs death events。
在 non-fiction 里面，一个很重要的概念是认可 inevitable 的
存在。正因为 inevitable 的存在，所以有 properly respond
inevitable 的重要性。
这个就是为啥娃那本 Leukemia 的书，花了整整一章谈论一个
小孩对她的 close friend's death on the similar but not
identical disease（different type of Leukemia) 的
response。娃还特地建议俺读那一章。 |
|
t*******r
发帖数: 22634 | 24 EQ is essential for facing life vs death events。
在 non-fiction 里面，一个很重要的概念是认可 inevitable 的
存在。正因为 inevitable 的存在，所以有 properly respond
inevitable 的重要性。
这个就是为啥娃那本 Leukemia 的书，花了整整一章谈论一个
小孩对她的 close friend's death on the similar but not
identical disease（different type of Leukemia) 的
response。娃还特地建议俺读那一章。 |
|
f******g
发帖数: 1003 | 25 楼主转移阵地了，好贴。
我也部分同意楼主，一些恶霸提出的概念确实有问题，导致不少人送死。
楼主列出的这几个领域，我不是全部了解，所以只说说我知道的。
我知道的好像p53的inhibitor在肿瘤方面没有什么作用。但是有一点很奇怪，在很多肿
瘤细胞里面,p53的突变率很高，而且小鼠模型里面，p53敲除确实可以导致各种肿瘤。
只能说肿瘤发生发展太复杂了。，不是一两个基因能说明问题的。
关于肿瘤干细胞，sean morrison在一篇nature文章中已经证明在某些tumor中(黑色素
瘤)，肿瘤干细胞是不存在的。
关于个性化治疗，我觉得这个还是很有发展前途的。最近有几篇高档次的文章表明在
myeloid leukemia病人中Dnmt3a中，有一个点突变频发，并且小鼠模型证明了这一点，
这样可能就找到了一个可能的myeloid leukemia致病因素，在对病人诊断筛选的时候，
这个突变可以作为一个指标来分类病人，这个应该就是个性化治疗。至于下一步的药物
选择，这就需要结构生物学的帮助了，看看时候这个突变引起Dnmt3a结构的变化，是否
能够找到靶点等等。
华大提出的肿瘤异质性这个概念一直... 阅读全帖 |
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w**********l
发帖数: 8501 | 26 【 以下文字转载自 Military 讨论区 】
发信人: babywhenugon (若林), 信区: Military
标 题: 纽约时报：50名核电站工人是日本最后的希望
发信站: BBS 未名空间站 (Tue Mar 15 22:12:55 2011, 美东)
Last Defense at Troubled Reactors: 50 Japanese Workers
By KEITH BRADSHER and HIROKO TABUCHI
A small crew of technicians, braving radiation and fire, became the only
people remaining at the Fukushima Daiichi Nuclear Power Station on Tuesday
— and perhaps Japan’s last chance of preventing a broader nuclear
catastrophe.
They crawl through labyrinths of equipment in... 阅读全帖 |
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E**********r
发帖数: 2743 | 27 Ariad +9%, reports commercial availability of Iclusig for adult CML patients
Jan 17 2014, 08:25
Ariad Pharmaceuticals (ARIA) +9% premarket after announcing the commercial
availability of Iclusig for adult patients with refractory chronic myeloid
leukemia and Philadelphia-chromosome positive acute lymphoblastic leukemia
in the U.S.
ARIA has begun shipping Iclusig to Biologics, its exclusive specialty
pharmacy, which is now filling prescriptions from physicians and
distributing the cancer medicine... 阅读全帖 |
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m******c
发帖数: 1202 | 28 Ever since Ariad Pharmaceuticals’ Ponatinib treatment for leukemia was
given the green light by American regulator, the FDA, industry majors have
been sniffing around. As its shares changed hands at $6.50, valuing the
Massachusetts-based company at around £800m, dealers heard whispers
from across the Pond that at least three international pharma groups
including US giant Eli Lilly have made ‘friendly approaches’ to the Ariad
board and are prepared to pay up to $20 a share in cash to gain co... 阅读全帖 |
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t*****A
发帖数: 311 | 29 朋友们请帮助一下这个有需要的朋友，求扩散求转发。
http://www.youcaring.com/medical-fundraiser/help-yili-fighting-
Yili is a young and vibrate young lady from Northern China. She came to US
on 2006 to embrace a new life. With many years of hard work, she obtained
her degree in lab science from Quincy College this year, 2013. Due to her
excellences in her studies, she was offered an internship and later a full
time position at St. Elizabeth Medical Center. She was the only student from
her graduating class who was offered... 阅读全帖 |
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y***n
发帖数: 6764 | 30 上次有人问出处，这里呢, 自己看吧，数据触目惊心。
http://www.examiner.com/article/concord-superfund-site-settleme
...
In particular, a Mass Department of Public Health analysis of cancer rates
from 2003-2007 in the town of Concord shows there were 28.5 percent more
women who developed kidney and renal pelvic cancer in Concord than was
expected. There also were 39.5 percent more women who developed breast
cancer, 96.1 percent more who developed multiple myeloma, 68.9 percent more
who developed ovarian cancer, 9.8 percen... 阅读全帖 |
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r****p
发帖数: 1949 | 31 生病是隐私，没必要拿出来大肆炒作。我尊重病人，但觉得拿病情作商业炒作比较
cheap，"连人家白血病的事都不放过"的恰恰是COLTS球队自己。题外话，Bill Walsh的
独生子死于leukemia，最后Bill Walsh自己也死于leukemia。 |
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R*****t
发帖数: 2115 | 32 《大年初一当跑步观众》（ 2-10-2013）
以往企鹅先生拍摄的跑步比赛，企鹅太太都是跑步者，而今天早晨企鹅太太第一次作为
观众参与Rhythm and Blues 5K （5公里） and Half Marathon （半程马拉松，21.1
公里）。这次跑步比赛的收入捐给以下4个非盈利/慈善公益机构：
（1） APHON ：for “Children with cancer and blood disorders and their
families receive the highest quality care”；
（2） San José Clinic：“to provide quality healthcare and education to
those with limited access to such services in an environment which respects
the dignity of each person”)；
（3） Legacy Community Health Services：“to le... 阅读全帖 |
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s*****e
发帖数: 970 | 33 It can cure one kind of leukemia (become manageable). There're dozens of
other leukemia out there. But it's nevertheless a remarkable achievement. |
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s**********p
发帖数: 17 | 34 Under Chen Zhu, the Shanghai Institute of Hematology at Rui-Jin
Hospital has become one of China's leading research groups.
Leukemia is the sixth deadliest cancer; it is especially ravaging
among the young. Chen Zhu, a member of the Chinese Academy of Sciences
and director of the Shanghai Institute of Hematology, has made
substantial headway in leukemia cell research and molecular biology.
He and his fellow researchers have published eight findings from their
work and have won the Kettering and |
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g********d
发帖数: 4174 | 35 白血病有很多种，砒霜成功的例子是治疗ACUTE PROMYELOCYTIC LEUKEMIA（APL），这
确实是中药里少有的几个成功的例子，和青蒿素一样是伟大的发现。但是不知道砒霜完
胜的结论是怎么来的，治疗NEWLY DIAGNOSED APL的STANDARD THERAPY不是砒霜，而是
ATRA+anthracycline-based chemotherapy,我猜ATRA就是所谓的全反式维甲酸吧，我只
看到一个中国的随机对照实验显示在这种情况下砒霜优于ATRA，
我还看到有其他数据表明砒霜不如ATRA+anthracycline-based chemotherapy，显然砒
霜更好的证据不足，要不然的的话，砒霜就是STANDARD THERAPY了 。砒霜只是在APL经
standard therapy治疗复发后是最好的选择，所以它是ATRA+anthracycline-based
chemotherapy的一个补充。（Miguel A. Sanz, Treatment of Acute Promyelocytic
Leukemia, Hematology, 2006）。
... 阅读全帖 |
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A*********R
发帖数: 11847 | 36 Thanks much for all the info.
They are very helpful for future reference.
My vet gave Leukemia shot for two of my kittens...I heard from my shelter
that this shot is only 40% effective and they can still have leukemia
afterwards.
vaccine |
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D*****t
发帖数: 1303 | 37 FIV/FeLV combo应该就能查出是否有leukemia了，我家猫就查了个FIV/FeLV
如果indoor养，或者家里没有得leukemia的猫，没必要打vac |
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A*********R
发帖数: 11847 | 38 Leukemia 好像就是白血病: Leukemia virus causes immune suppression, and
development of cancerous disease. There's no treatment. 好像是针对outdoor的
，但indoor 如果expose to 带病体的猫也会染上的。有了就没得治了，但好像听谁谁
说过，疫苗也不是100%有效的，说即使打了疫苗遇上带病体还会感染。 所以最安全就
是不要接触带病体了。
但愿你家两娃都没反应。
多多昨天晚上拉稀了，今天早晨起来明显精神不好，昨晚也没有照例上床要摸，也没挨
着我睡。 早知道这样也就和蜜咪一样，一次打一针好了。
喂了点酸奶，娃还喜欢吃。昨天晚上睡觉那个愧疚阿，为了省几个臭银子害得两娃在
carrier里呆了近两个小时。老妈俺有本事该和IRS斗，让IRS把俺缴的税给吐回来。 |
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t******g
发帖数: 3641 | 39 加个问题：那种"blood disease kind of leukemia"血检能检出来吗？那个不是FeLV是
吗？paltelet low是不是基本也可以排除这种leukemia？ |
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b******s
发帖数: 5365 | 40 Low platelet can not rule out the possibility of leukemia. However, other
virus infection can also cause low platelet counts.
是吗？paltelet low是不是基本也可以排除这种leukemia？
我不能让咪宝就这么死了，她还吃饭吃的很好，还会给自己洗脸，舔毛。我搂着她，她
还会把脑袋 |
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t******g
发帖数: 3641 | 41 【10.28 最后一诊归来】
今日见的是这里最大的牛，嗯，人非常非常的nice
捏把捏把了一下咪宝，量体温啥的，一切正常。他说，如果咪宝是来wellness check，
那么他会说她一切健康。
连Toxo都不是，血检表明，她曾经expose过，有抗体了，但是现在不是Toxo。
不是leukemia，不是FIP，也不是dry FIP。因为这些病，虽然有up and down，但是只
是病的轻还是病的重，不会像咪宝这样完全看不出问题来。
他还捏了咪宝的关节，没有任何组织发炎什么的。眼睛什么的都很好。
他能想到的，一个小可能是soft tissue发炎，没看出来。不过这个可能很小，两个vet
，7张xray都没看出来，而咪宝又那么痛苦，不可能是小发炎了。另一个他能想到的可
能就是calicivirus，疫苗（FVRCP）的反应。他说，很少的小猫打针两周内会有这个反
应。如果下次打针两周内出现同样的症状，则可以证实这个问题了，那么以后她就不能
打三联疫苗了，或者换成nasal的。
一次比一次消息好。开始是leukemia，然后是FIP，然后是FIP或者Toxo，最后这次连
Toxo都不是，可... 阅读全帖 |
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N*****y
发帖数: 2959 | 42 很多有心的宠友可能已经或多或少的知道了小小年糕的事情，私下里收到不少消息表示
关心。谢谢你们记挂，也谢谢你们照顾我们的情绪和隐私。
其实挣扎了很久不知道是不是应该发这个帖子，不过本着对家咪认真负责的态度，还是
说一下。向自己表个决心，给大家提个醒。再集思广益一下，看看有没有病友什么的。
没有写主题，因为这样不好搜索。说真的，大家看过就看过，不想再被提起此事，真的
很心痛。以后，我们只想和家咪过正常喵的生活。
以下纯文字叙述，不加任何的感情色彩。请看官有点心理准备。
先说小小年糕吧。。。
是的，她们已经去了彩虹桥。
小黑走的很突然，当时并没有查出病因。
小黄后来确诊是FELV+ 引起的贫血。
因为feline leukemia virus（FELV）是会通过母婴传播的，而小小年糕从出生开始就
没有见过年糕和cereal以外的猫。所以，年糕这个最大的嫌疑喵，需要重新检查。
话说年糕当年被捡回来之后我们是带她验过felv的，因为这个virus也会通过唾液传播
给别的猫（一般是猫猫打架撕咬的时候）。所以没有确认年糕negative之前，我们是不
会将她和cereal放在一起生活的。
和vet说... 阅读全帖 |
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m*******u
发帖数: 6052 | 43 我家三只因为经常出去玩，所以每年都去打rabies, 就是狂犬疫苗吧？
然后vet说因为他们会抓鸟和兔子等，容易传染 leukemia，所以又推荐打了这个（去年
没打），而且得打两次。但是我回来之后查了查，发现他的话很误导，leukemia主要是
猫之间传染的，特别是家猫和野猫。我想问的是，这个对经常出门的猫，有必要年年打
么？
还有，今天vet不再，只有护士在，她说根据vet留的单子，还需要打FVRCP,叫什么
distemper, 我去查了一下，是个三合一的 Feline Viral Rhinotracheitis,
Calicivirus, Panleukopenia，基本就是比气管炎，某种严重的养胃炎，以及猫瘟。去
年是跟rabies一起打的。不知道今年为什么分开了。
总计每猫挨了四针，每猫各花费75刀。 |
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R******0
发帖数: 6158 | 44 我家indoor猫三只，都是每年打rabies，隔三年打一次FVRCP（只有第一年和第二年是
连续两年打），专门找的副作用小的non-adjuvanted vaccine，平均每针每猫二十多刀。
leukemia的不了解，一般indoor肯定是不需要，经常往外跑可能接触别的猫的话还是谨
慎一些吧，不过leukemia的疫苗不像前面两种那样有效，就是打了也仍然可能会感染。
。。 |
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T*******e
发帖数: 4928 | 45 要小心。我家二宝在打完feline leukemia的第一轮预防针后一周
突然后腿瘸了，连litter box都要我抱它进，根本不能跳高。就是趴着不动，
后腿很疼的样子。
到医院一通检验，花了六百多刀，说是可能摔伤了，炎症发烧。开了止疼药和消炎药
。后来养了一个月好了。但是我再也没有让二宝打feline leukemia第二轮预防针。因
为我怀疑有问题，但是也不能确定。 |
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j*****e
发帖数: 564 | 46 BIggest bless!!!
Recently we made a donation to the Leukemia @Lymphoma Society. They have a
phone number
1-800-955-4572 for patient services, research updates, and educational
materials and more. The website is http://www.leukemia-lymphoma.org/hm_lls. I don't know if the
information there is of any help...
Hope that your sister can recover soon. |
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l**********n
发帖数: 240 | 47 Josef Martin Penninger
Most significant scientific contributions:
Our basic approach is to genetically manipulate and change genes in mice and
to
determine the effects of these mutations in development of the whole
organism and in
diseases. From these mutations we are trying to establish basic principles
of
development and basic mechanisms of disease pathogenesis. My laboratory
focuses on
heart diseases, autoimmune diseases and cancers, and bone diseases. On all
the listed
contributions below I ... 阅读全帖 |
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c**i
发帖数: 6973 | 48 Peter Landers, New Breast Cancer Drug Found Deep in the Sea. Wall Street
Journal, Jan. 4, 2010.
http://online.wsj.com/article/SB1000142405274870411150457605977
("A study found it [Halaven] extended the life of patients with advanced
breast cancer by about two-and-1/2 months, to 13 months")
My comment:
(a) Eisai Co., Ltd. エーザイ株式会社
(a public company; headquarters Tokyo; established in 1941 by Toyoji NAITO
内藤 豊次 as Nohon Eisai Co., Ltd. 日本衛材（衛生材料の略。具体的には絆創膏
や包帯の事))
ja.wikipedia.org
(b) eribulin
htt... 阅读全帖 |
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s*****h
发帖数: 7 | 49 Title: Donor KIR Genes 2DL5A, 2DS1 and 3DS1 Are Associated with a Reduced
Rate of Leukemia Relapse After HLA-Identical Sibling Stem Cell
Transplantation for Acute Myeloid Leukemia but Not Other Hematologic
Malignancies
Publication date and journal issue: "Biology of Blood and Marrow
Transplantation" Volume 16, Issue 9 , Pages 1257-1264, September 2010
PMID: 20302958
Please send the file to s********[email protected]. Thanks a million. |
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h*****t
发帖数: 103 | 50 为什么非要是突变呢？
CSC也是属于Cancer的吧？或者是良性的？一旦生长上面出现无法控制的情况，就变成
恶的了？另外，良性的肿瘤有没有tumor stem cell，原来遇见过子宫肌瘤，西瓜那样
大，里面是否也存在tumor stem cell呢？
CSC现在争论是否已经达成一致了？还是Cancer Initiating Cell?
不过从Leukemia来看，CSC应该是存在的，尽管不如HSC具有那样明确的hierarcy；对于
实体肿瘤，很多认为CSC也是存在的，尤其是今年Cell上发表Barret食管癌相关的那
篇paper也提示存在这么一个状态；而从lymphoma的研究来看，CSC好像还没有明确的找到，一方面可能因为lymphoma本身分类比较复杂，HL里面有人认为其中的小细胞可能是CSC，但也有人认为
患者体内CD20+的细胞为HL的CSC；而对于NHL，可能发展到leukemia的时候，会有CSC，
若只停留在lymphoma的状态，好像也还没有CSC的报道。其他器官如breast、prostate
、liver、brain等似乎都有很多CSC的报道。
但是有人质疑C... 阅读全帖 |
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