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全部话题 - 话题: inhibiting
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s**u
发帖数: 9035
1
发信人: shmu (shmu), 信区: FDU
标 题: 一复旦校友从著名的Lab海归杭州师范大学副教授
发信站: BBS 未名空间站 (Sun Oct 21 09:15:12 2012, 美东)
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
... 阅读全帖
N*********6
发帖数: 2302
2
【 以下文字转载自 Biology 讨论区 】
发信人: Narcissus26 (Jane), 信区: Biology
标 题: 帮师弟寻找一个postdoc 位置,谢谢
发信站: BBS 未名空间站 (Tue Dec 29 08:56:37 2015, 美东)
人在国内,有11篇文章。有兴趣的PI, 请email me ::[email protected]
/* */
谢谢!
1. Kang H, Cao S, Chen T, Jiang Z, Liu Z, Li Z, Xu Q, Lin Q, WeiS. The poor
recovery of neuromyelitis optica spectrum disorder is associated with a
lower level of CXCL12 in the human brain. J Neuroimm, 289:56-61, 2015.(co-
first author)
2. Chen T, Li Z, Jiang Z, Liu Z, Xu Q, Huang D, Lin Q, Wei.S (... 阅读全帖
s**u
发帖数: 9035
3
发信人: shmu (shmu), 信区: FDU
标 题: 一复旦校友从著名的Lab海归杭州师范大学副教授
发信站: BBS 未名空间站 (Sun Oct 21 09:15:12 2012, 美东)
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
... 阅读全帖
s**u
发帖数: 9035
4
发信人: shmu (shmu), 信区: FDU
标 题: 一复旦校友从著名的Lab海归杭州师范大学副教授
发信站: BBS 未名空间站 (Sun Oct 21 09:15:12 2012, 美东)
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
... 阅读全帖
J*****3
发帖数: 4298
5
来自主题: TrustInJesus版 - 信了教就没有离婚,凶杀,吸毒了
http://home.comcast.net/~pobrien48/serial_killers.htm
Serial Killers:
The FBI gave the standard profile of a serial killer, He is a person with
few friends. He became much more religious just before he started murdering
people. After reading all the available studies I could find and studying
all the articles in the newspapers for over 30 years, I find what is most
outstanding is Serial killers were sexually inhibited by their strong
religious upbringing.
Nearly all serial killers are very devou... 阅读全帖
s**u
发帖数: 9035
6
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
Research Associate (助教) at Fudan University
Education
Tufts University
Fudan U... 阅读全帖
s**u
发帖数: 9035
7
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
Research Associate (助教) at Fudan University
Education
Tufts University
Fudan U... 阅读全帖
s**u
发帖数: 9035
8
发信人: shmu (shmu), 信区: FDU
标 题: 一复旦校友从著名的Lab海归杭州师范大学副教授
发信站: BBS 未名空间站 (Sun Oct 21 09:15:12 2012, 美东)
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
... 阅读全帖
s**u
发帖数: 9035
9
发信人: shmu (shmu), 信区: FDU
标 题: 一复旦校友从著名的Lab海归杭州师范大学副教授
发信站: BBS 未名空间站 (Sun Oct 21 09:15:12 2012, 美东)
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
... 阅读全帖
k*****n
发帖数: 417
10
来自主题: Biology版 - 列几个被引用过万的PIs
Their top5 highly cited research papers:
Wei Gu:
Title: Negative control of p53 by Sir2 alpha promotes cell survival under
stress
Times Cited: 822 (from Web of Science)
Title: Deacetylation of p53 modulates its effect on cell growth and
apoptosis
Times Cited: 331 (from Web of Science)
Title: Deubiquitination of p53 by HAUSP is an important pathway for p53
stabilization
Times Cited: 319 (from Web of Science)
Title: Mono-versus polyubiquitination: Differential control of p53 fate by
Mdm2
Times Ci... 阅读全帖
E**********1
发帖数: 73
11

I've checked that paper. Based on my understanding, the paper said ATP
stimulation can temporarily inhibit respiration and reduce mitochondrial
membrane potential, so inhibit mitochondrial Ca2+ uptake. After temporary
inhibition of Ca2+ uptake, ATP is consumed and mitochondrial respiration
resumed and cause mitochondrial Ca2+ boost. And the boost after ATP
stimulation can reflect the ability of cellular respiration.
But this still doesn't solve my problem, which needs to increase cytoplasmic
Ca... 阅读全帖
V***b
发帖数: 3419
12
来自主题: Biology版 - 有没有善使rapamycin的大仙?
The reason that rapamycin inhibits mTorc2 is that long-term treatment with
rapamycin, overnight for example (concentration doesn't matter), inhibits
mTorc2 complex assembly, but rather inhibits its kinase activity directly.
s**u
发帖数: 9035
13
发信人: shmu (shmu), 信区: FDU
标 题: 一复旦校友从著名的Lab海归杭州师范大学副教授
发信站: BBS 未名空间站 (Sun Oct 21 08:28:35 2012, 美东)
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
... 阅读全帖
s**u
发帖数: 9035
14
发信人: shmu (shmu), 信区: FDU
标 题: 一复旦校友从著名的Lab海归杭州师范大学副教授
发信站: BBS 未名空间站 (Sun Oct 21 08:28:35 2012, 美东)
我们有个校友,1998年硕士毕业留校,2001年来美国,2006年Tufts University Ph.D.
2010年海归杭州师范大学副教授。
zhi Lian directly
View Full Profile
Fuzhi Lian's Overview
Current
Associate Professor at Hangzhou Normal University
Past
Scientist III at USDA Human Nutrition Research Center on Aging at
Tufts University
Postdoctoral Associate at USDA Human Nutrition Research Center on
Aging at Tufts University
... 阅读全帖
m**********3
发帖数: 706
15
今天查文献,关键词搜索" survival,retinal neurons". 有一篇文章让我很迷惑。仔
细一看名字和地址,莫非是气功大师的杰作。求鉴定。如果真是,那严大师应该是所有
这些大师,教主里头科研素质最高的了。放在国内都可以PHD毕业了。甚至秒杀大部分
博导.
Int J Neurosci. 2002 Oct;112(10):1209-27.
XY99-5038 promotes long-term survival of cultured retinal neurons.
Yan X, Fong YT, Wolf D, Shen H, Zaharia M, Wang J, Wolf G, Li F, Lee GD, Cao
W.
Source
Institute of Chongqing Traditional Chinese Medicine, Chongqing, Sichuang, P.
R. of China.
Abstract
We have previously reported that XY99-5038, a preparation from a spec... 阅读全帖
g*********3
发帖数: 177
16
Just my opinion/impression:
1) How to define "TCA is inhibited":
Sometimes it is not totally inhibited in that whole TCA Cycle. It has
another name: Truncated TCA cycle.
2) as xhzhou said: the intermediate products in glycolysis can enter into
other pathways---"whatever pathways"---synthesized into "macromolecules".
The "whatever pathways" & "macromolecules" are hot filed, which is more
complex than the textbook. Many of them are not discovered yet and may be
tumor-specific SUCH as the oncometab... 阅读全帖
N*********6
发帖数: 2302
17
人在国内,有11篇文章。有兴趣的PI, 请email me ::[email protected]
/* */
谢谢!
1. Kang H, Cao S, Chen T, Jiang Z, Liu Z, Li Z, Xu Q, Lin Q, WeiS. The poor
recovery of neuromyelitis optica spectrum disorder is associated with a
lower level of CXCL12 in the human brain. J Neuroimm, 289:56-61, 2015.(co-
first author)
2. Chen T, Li Z, Jiang Z, Liu Z, Xu Q, Huang D, Lin Q, Wei.S (2015) Changes
of CXCL12, CXCL14 and PDGF levels in the brain of patients with idiopathic
demyelinating optic neuritis and neuromyeliti... 阅读全帖

发帖数: 1
18
读了一下这篇文章,不喜欢这种研究思路,不能够称之为科学。
该实验室主页上面所挂出来的以下一些文章中,有很多引用率非常的低。
ROCKII inhibition promotes the maturation of human pancreatic beta-like
cells. Nature Communications. 2017 Academic Article GET IT
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates
that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.
Cell Stem Cell. 2017 Academic Article GET IT
A Modular Platform for Differentiation of Human PSCs into All Major
Ectodermal Lineages. Cell Stem Cell. ... 阅读全帖
R*j
发帖数: 248
19
来自主题: Pharmaceutical版 - 请教一段话得意思
举例来说,在drug metabolism中,所谓mechanism-based inhibition (or, suicide
inhibition)就是因为reactive metabolite 和P450 enzyme 形成covalent bond,使
P450失活。而且也有kinetic equation描述这种inhibition.
所以我觉得下面这段话说得不确切啊。这个statement是最近的文献上引的?还是很早
以前的书上的话?

thx

发帖数: 1
20
诺贝尔奖爆露最大丑闻,真相浮出
诺贝尔医学奖项爆露最大丑闻,把奖项给了残害无数生灵,残害人类的日本骗子科学家
。这是人类历史上最悲哀的时刻。我所有的研究都揭示癌症,老年痴呆,糖尿病现阶段
广泛地流行,是日本人几十年孜孜不倦刻意造成的,是一种人造的疾病。他们给亿万的
生灵造成了终生的痛苦,他们应该被送上反人类的法庭去审判,而不是被奖赏。他应该
被逮捕,交代日本人是用什么样的手段伤害全世界无辜的人群的,如何制造癌症,老年
痴呆,糖尿病患者的。如何通过这些人体实验,给医药公司攫取了大量的财富。今年的
获得者是Yoshinori Ohsumi. 查看了一下去年的获得者,竟然也有个日本凶手Satoshi
Omura. 他的研究更是惨不忍睹,他的一生就是罪恶的一生,不知道害死了多少无辜的
人。只有中国的获得者是无辜的,值得敬佩的,以身献身科学的。说到底,如果不是这
些可恨的美国人,日本人传播这些寄生虫,我们的科学家也不用有那么多的牺牲来攻克
这些难题。有一天,我睡在沙发上,发现有人刺进了我的鼻子里,不知道他们往我身上
注射了什么。为什么我知道,因为他们研究的这些东西都用在了我的身上,和我身边的
... 阅读全帖
w*********g
发帖数: 30882
21
平井宪夫揭示日本核电业惊天内幕——素人造核电,豆腐渣工程
作者:蜀中行 更新时间:2011-3-16
设施配管1级技士平井宪夫(1997年1月因癌症逝世)生前的最后吶喊。
/来自中华网社区 club.china.com/
/来自中华网社区 club.china.com/
关于平井宪夫:
1997年1月逝世。设施配管1级技士,核电事故调查国民会议顾问,核电劳工救济中
心代表,北陆电力志贺核电厂停止诉讼原告特别辅佐人,东北电力女川核电停止诉讼原
告特别辅佐人,福岛二号核电厂三号机运转停止诉讼原告证人。「核电劳工救济中心代
表」在他仙逝后,因后继无人关闭
"我不是反核运动家。这20年来,我一直在核电厂工作。社会上有听不完的拥核反
核理论,但我只想在这里告诉大家:「所谓的核电厂是这样一回事。」大部份的人都不
知道核电内部的实际情形。希望大家有耐心把这篇文章读完。所谓核电,跟各位所想的
或许有点出入。在那里,每天都有遭受放射线污染的工人,以及严重的岐视产生。
我的专长,是负责大型化学工场的内部配管施工与维修。快30岁时,日本掀起了一
阵核电建设的... 阅读全帖
s********n
发帖数: 26222
22
方舟子在此文中说“虫子不吃的, 人能吃吗”是中国人的质疑, 而美国人是不会问这
样的问题的, 这显然是骗人的。见下文和其中引用的文献, 其中不少是美国人的科研

"Comments on the human health impact of Bacillus thuringiensis toxin gene
product in genetically modified crops"
EPA Review Docket Number OPP-00678B
Professor Joe Cummins
Professor Emeritus of Genetics
University of Western Ontario
I have studied the Environment Protection Agency (EPA) document "Bt Plant-
Pesticides Biopesticides Registration Action Document B. HUMAN HEALTH
ASSESSMENT" and comment in the following ... 阅读全帖
r********n
发帖数: 7441
23
发信人: conti (conti), 信区: TsinghuaCent
标 题: zz pk饶毅进入第二轮的张旭的背景
发信站: 水木社区 (Sun Aug 28 15:38:09 2011), 站内
如果神经方向就只能上一个候选人,那么张旭入选还真是一点也不出格
发信人: WeiLiao (WeiLiao), 信区: Biology
标 题: 张旭的publications
发信站: BBS 未名空间站 (Sun Aug 28 01:39:20 2011, 美东)
去查了一下,张旭总共发表了90多篇英文文章(不算中文)。回国之后作为联系作者也
有快20篇了。其中有cell, neuron, Journal of neuroscience, PNAS 好多篇。
而且他
1995年就回国了,那个时候国内的环境有多差不用说了吧。这也快20年了。比饶益
2007
年才全职回去多了12年。比起培养的中国学生也多多了,算国内贡献肯定不会小。如果
他一直留在国外,成就未必就比饶差。谁把饶益的文章列一列。国内多少篇,总共多少
篇,培养了多少中国学生?
1. Li KC, Wang F, ... 阅读全帖
K**********n
发帖数: 1197
24

跟这帮自称理科的文科生物wsn实在纠缠不清楚。给丫们上点洋大人自己的说法吧,而
且都是学术圈的,已有reference一堆,其中一份是著名的兰德公司的报告。
另外,美国和澳洲已立法限制使用脑波扫描仪,拿脑波扫描仪扫本国公民已是联邦法的
重罪。不过这个比较难的是你无法证实谁接收了你的脑信号。所以立了法跟没立一个样。
Remote Mind Control Technology

Reprinted from SECRET AND SUPPRESSED: BANNED IDEAS AND HIDDEN
HISTORY, edited by Jim Keith, $12.95, available from
1-800-680-INET.
There had been an ongoing controversy over health effects of electromagnetic
fields (EMF) for years (e.g., extremely low frequency radiation and the
Navy's Project Sea... 阅读全帖

发帖数: 1
25
诺贝尔奖爆露最大丑闻,真相浮出
诺贝尔医学奖项爆露最大丑闻,把奖项给了残害无数生灵,残害人类的日本骗子科学家
。这是人类历史上最悲哀的时刻。我所有的研究都揭示癌症,老年痴呆,糖尿病现阶段
广泛地流行,是日本人几十年孜孜不倦刻意造成的,是一种人造的疾病。他们给亿万的
生灵造成了终生的痛苦,他们应该被送上反人类的法庭去审判,而不是被奖赏。他应该
被逮捕,交代日本人是用什么样的手段伤害全世界无辜的人群的,如何制造癌症,老年
痴呆,糖尿病患者的。如何通过这些人体实验,给医药公司攫取了大量的财富。今年的
获得者是Yoshinori Ohsumi. 查看了一下去年的获得者,竟然也有个日本凶手Satoshi
Omura. 他的研究更是惨不忍睹,他的一生就是罪恶的一生,不知道害死了多少无辜的
人。只有中国的获得者是无辜的,值得敬佩的,以身献身科学的。说到底,如果不是这
些可恨的美国人,日本人传播这些寄生虫,我们的科学家也不用有那么多的牺牲来攻克
这些难题。有一天,我睡在沙发上,发现有人刺进了我的鼻子里,不知道他们往我身上
注射了什么。为什么我知道,因为他们研究的这些东西都用在了我的身上,和我身边的
... 阅读全帖

发帖数: 1
26
07 Nov 2019
Just as the clamor about Biogen’s seeking FDA approval for aducanumab with
one positive Phase 3 trial started to die down, a Chinese company garnered a
regulatory thumbs-up for its drug, also with one Phase 3 trial. On November
2, Shanghai Green Valley Pharmaceuticals announced that China’s National
Medical Product Administration (NMPA) had conditionally approved GV-971, aka
oligomannate, for the treatment of mild to moderate Alzheimer’s disease.
Full approval, expected to come in sp... 阅读全帖
n*********8
发帖数: 1137
27
美国病毒改造监控计划始末:为改造全新病毒 从中国拿走上万件样本?
送交者: 两极的世界[♂★★★声望勋衔13★★★♂] 于 2020-02-29 17:41 已读 469
次 大字阅读 两极的世界的个人频道
“最危险的人造病毒”:病毒学家争相改造病毒研究引发公共安全担忧
2014年10月17日下午,病毒学家Ralph Baric博士没有照例来到他在北卡罗来纳大学教
堂山分校的实验室,他正在为自己女儿周末的婚礼做最后的准备。 此时的他并不知道
,奥巴马政府由于对实验室使用SARS, MERS和流感等病毒,进行功能获得性(gain of
function)改造的研究,对公共健康构成的潜在威胁的担忧,通过白宫科技政策办公室
联合美国卫生与公众服务部发布禁令,宣布中止对类似研究的资金资助[1],并要求相
关领域的研究人员立即停止相关的研究,直到研究项目的风险和收益被美国国家生物安
全科学顾问委员会(NSABB)和美国国家学院国家科学研究委员会(NRC)的专家进行评估后
方可继续[2]。
这其中就有武汉病毒所石正丽博士的研究团队与Ralph Baric博士的合作项目:一个正
在进... 阅读全帖
O******s
发帖数: 59
28
【 以下文字转载自 Biology 讨论区 】
发信人: OldHands (老手), 信区: Biology
标 题: 吐槽一个bioinformatics老板
发信站: BBS 未名空间站 (Fri Sep 12 23:05:54 2014, 美东)
老板自称是做translational bioinformatics的,
其phd也算是正宗machine learning出身的,
但是研究思路上真是不敢恭维,
做完一个database,上线,发个小文章,
再继续做另外一个生物信息database,做个网站,上线,发个文章;
已经拿这种思路申请了两次R01了,结果都没中(中了才怪呢!)
这种研究思路就是打浆糊,除了catalog别人的发现,毫无创新;
最近还要搞drug repurposing,
也是利用前人发的paper,做text mining, 在link到某些drug,
看看能不能把同一类的drug combine起来inhibit一个circuit,
做inhibition modeling,
这种研究思路非常危险,第一,你是假设以前的paper都是正确的;
第二,做m... 阅读全帖

发帖数: 1
29
来自主题: Faculty版 - Jan's lab : 这里有弟子么?

Download pdf published by SfN (Chapter from 'The History of Neuroscience in
Autobiography, Volume 8' edited by Larry R. Squire)
Yuh-Nung Jan's CV
Lily Jan's CV
Yuh-Nung Jan and Lily Jan
Birth
Family History and Growing Up
National Taiwan University
The Hiking Trip to Shitou in the Spring of 1967
Graduate School Application
Graduate Study at Caltech (1968锟974)
Seymour Benzer Lab (1974锟977)
Steve Kuffler锟絪 Lab at H... 阅读全帖
E*********r
发帖数: 4984
30
来自主题: Stock版 - how to lower chlosterol?
I think I am probably the best person to answer this question as one of my
projects at San Francisco General Hospital is to differentiate cholesterol
imbalance. There are two major routes for cholesterol accumulation in the
body.
The first one is through in vivo biosynthesis via a key enzyme called HMGCoA
reductase. Therefore, in order to lower cholesterol based on de novo
systhesis, a drug family called statins, is widely used because it inhibits
this key enzyme. Nowadays, measuring the conc... 阅读全帖
L******r
发帖数: 141
31
来自主题: Immigration版 - 怎样写好推荐信 EB1A/B
All the materials were taken from Administrative Decisions (Aliens with Extraordinary Ability/ Outstanding Professors and Researchers). 所以这些话是权威!!!
I downloaded All the AAO decisions for the past three years. I read one by one for a total number of more than 200 decisions. I took good paragraphs from recommendation letters which IOs thought have met criterion of contribution. Because the works were from PDF files, I had to reformat them into word file.
It took me many hours to do the work and I... 阅读全帖
w*****t
发帖数: 179
32
来自主题: Immigration版 - 另一个审稿机会
Thank you for providing the review opportunity, I have been working in the
molecular biology for over 15 years and published some papers in journals
like Journal of Cell Biology, Journal of General Virology et al., . Also I
have reviewed over 20 manuscripts for 10 journals. Hopefully these
experiences will help me to catch this opportunity. If you need further
detail information regarding my qualification, please let me know (zwang1@
wpahs.org). Please find my CV below. Thanks a lot.
Zhimin Wang... 阅读全帖
F**9
发帖数: 56
33
来自主题: Immigration版 - Review opportunity. Journal: Corrosion Science
Any one interested, please email me.
review opportunity. Journal: Corrosion Science
ABSTRACT:
The possibility of using newly synthesize N,N?-bis(4-hydroxybenzaldehyde)-1
,2-cyclohexan diimine (4-HBC) Schiff base as a corrosion inhibitor of API 5L
steel in 1 M HCl solution was investigated by polarization curves, AC
impedance measurements, current transient and SEM and AFM techniques. It
was shown that the inhibition effectiveness increases with an increase in
the concentration of 4-HBC and a de... 阅读全帖
d****5
发帖数: 202
34
来自主题: Immigration版 - [Gone]推荐审稿
Journal of Biomolecular Structure & Dynamics
TITLE: Understanding the interaction determinants of CAPN1 inhibition by
CAST4 from bovines: insights from molecular modeling
ABSTRACT:
The activated mammalian CAPN-structures, the CAPN/CAST complex in particular
, have become an invaluable target model using the structure-based virtual
screening of drug candidates from discovery phase to development for over-
activated CAPN linked to several diseases such as post-ischemic injury and
cataract formatio... 阅读全帖
i********n
发帖数: 171
35
来自主题: Immigration版 - 审稿 IF 2
8.Xiaoxianggou attenuates atherosclerotic plaque formation in endogenous
high Ang II ApoE-/- mice via the inhibition of miR-203 on the expression of
Ets-2 in endothelial cells
9.Loss of Raf kinase inhibitor protein is associated with malignant
progression in hepatic fibrosis
10.Bio-fabricated silver nanoparticles preferentially targets gram positive
depending on cell surface charge
11.Rosiglitazone elevates sensitization of drug-resistant oral epidermoid
carcinoma cells to vincristine by G2/M-ph... 阅读全帖
f********6
发帖数: 195
36
来自主题: Immigration版 - [gone] 审稿,生物材料方向
TITLE: The comparision of the Wnt signalling pathway inhibitor delivered
electrospun nanoyarn fabricated with two methods for the application of
urethroplasty
Journal of Materials Chemistry B
ABSTRACT:
Urethral stricture is a common disease caused by over-expression of
extracellular matrix from fibroblast. However, the fibroblasts is a main
type of cells for the repair of urethra.Here, we compared two nanoyarn
scaffolds with the characteristics for improving fibroblasts infiltration
but inhibiti... 阅读全帖
i********n
发帖数: 171
37
来自主题: Immigration版 - Reviewer needed Biomedicine
MS 1. Overview on experimental models of interactions between
nanoparticles and the immune system
MS 2. Long non-coding RNA MEG3 inhibits microRNA-125a-5p expression and
induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura
MS 3. BZ-26, Novel GW9662 Derivate, Attenuated Inflammation by Inhibiting
Inflammatory Macrophages Differentiation and Activation
Send your CV and MS # to [email protected]/* */, and please reply here with MS #.
Thanks
i********n
发帖数: 171
38
来自主题: Immigration版 - 生物医学文章13篇找审稿人
请发简历及你想审稿的文章编号,可以多选。
到[email protected]/* */
1. Combination of 2-deoxy D-glucose and metformin for synergistic
inhibition of non-small cell lung cancer: A reactive oxygen species and P-
p38 mediated mechanism
2. MYC gene regulating the occurrence and metastasis of prostate cancer
by STAT signaling pathways
3. Ursolic Acid Mediates Hepatic Protection through enhancing of anti-
aging biomarkers.
4. New insight on using aged garlic extract against toxic impacts of
titanium dioxide... 阅读全帖
G****a
发帖数: 10208
39
来自主题: Missouri版 - zz Amgen to Buy Onyx for $10.4 Billion
Although Amgen is the world’s biggest biotechnology company, the drug maker
has been mostly absent from one of the industry’s biggest and fastest-
growing markets: cancer drugs.
It took a big step to fix that on Sunday, agreeing to buy Onyx
Pharmaceuticals for about $10.4 billion in cash to gain access to the
company’s three anticancer treatments.
Under the terms of Sunday’s deal, Amgen will offer $125 a share in cash
through a tender offer for Onyx’s shares. The transaction is expected to
close... 阅读全帖
d*****n
发帖数: 908
40
来自主题: GunsAndGears版 - 贴一个手枪子弹停止率的具体数据
HANDGUN AMMUNITION:
SELF DEFENSE
Ammunition manufactured in the United States is among the finest in the
world. For intended defensive uses, the gun owner will not go wrong in
selecting ammunition produced by the most widely recognized manufacturers.
These include CCI/Speer, Cor-Bon, Federal, Remington, and Winchester.
Allow no margin for error in protecting one's life. Avoid potentially
unreliable ammunition that is hand loaded, re-loaded, or of dubious quality
foreign manufacture when ch... 阅读全帖
p*********l
发帖数: 26270
41
来自主题: loseweight版 - 减肥可以喝红酒么?
http://www.sparkpeople.com/resource/nutrition_articles.asp?id=5
Alcohol is metabolized differently than other foods and beverages. Under
normal conditions, your body gets its energy from the calories in
carbohydrates, fats and proteins, which are slowly digested and absorbed
within the gastrointestinal system. However, this digestive process changes
when alcohol is present. When you drink alcohol, it gets immediate attention
(because it is viewed by the body as a toxin) and needs no digestion.
O... 阅读全帖
d******0
发帖数: 22800
42
来自主题: Running版 - 今天在expo发现个神物
这个好。。贴贴脚丫子防止水泡应该没啥大不了的。
不过要贴的专业。。这个人说的好像有点道理。
5.0 out of 5 stars You need to know what you are doing..., August 19, 2010
By Headless (USA) - See all my reviews
This review is from: Kinesio Tex Tape, Red, 2 inch x16.4 ft (Health and
Beauty)
I am a CKTP...or Certified Kinesio Taping Practitioner. I am also a sports
med. doctor and treat amateur and professional athletes. I can attest to the
fact that you need a good knowledge of kinesiology and biomechanics to
maximize the effects of this tape. Th... 阅读全帖
b***m
发帖数: 2112
43
来自主题: Running版 - 消炎药有用吗?
最近做功课研究消除疼痛的办法,看到下面这边文章。大意似乎是:
1)炎症是身体对抗伤痛的自然反应,是身体自我修复过程的正常症状;
2)药物消除炎症,同时也抑制了身体的自我修复过程,反而不利于伤痛的恢复;
3)消炎药不能明显提高比赛成绩。
根据这篇文章的说法,我觉得ibuprofen或Advil最大的效果可能是止痛(类似麻醉剂,
消除或削弱大脑对疼痛的感受)。疼痛要求人不要过度使用身体;大脑不觉得疼了,就
会继续正常(其实是超量)使用身体。后果可能是短时间内保持了成绩,但加速了肌肉
撕裂,伤病加重。
我英语不太好,英语好的可以再总结一下。
Ibuprofen and Running
Written by Coach Jeff
As a competitive runner and a coach, I am always striving to find the
perfect balance between recovery and adaptation.
If you’re reading this post, you too have probably come across you... 阅读全帖
f*1
发帖数: 837
44
来自主题: gardening版 - 关于种草的问题
I wouldn't use it. Halts has the active ingredient of Pendimethalin and is
marketed as a Crabgrass pre-emergent preventer. It will also prevent grass
seeds from germination so if you use it when planting grass from seeds, you
won't get any grass!
You may argue that sods are grass that have already germinated, so it wouldn
't be that bad. However, Pendimethalin (as well as many other pre-emergent
herbicides) also has early post-emergent function and it may inhibit
initial root growth, while it... 阅读全帖
p********3
发帖数: 5750
45
以下有文献是讲中药Lead中毒的:我懒得去筛选, 先发这个。 还有很多其他的比如癌
症的, 肾脏毒性的, 单个疾病双盲单盲科研的。我就不一一列举了。
参看50, 51, 70, 73-75.
REFERENCES 1 Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998; 280:1604.
2 Blumenthal M (Ed). The ABC Clinical Guide to Herbs. American Botanical Council/Thieme, New York 2003.
3 Kaptchuk TJ. Acupuncture: theory, efficacy, and practice. Ann Intern Med 2002; 136:374.
4 Farnsworth NR, Akerele O, Bingel AS, et al. Med... 阅读全帖
J*****3
发帖数: 4298
46
http://home.comcast.net/~pobrien48/serial_killers.htm
Serial Killers:
The FBI gave the standard profile of a serial killer, He is a person with
few friends. He became much more religious just before he started murdering
people. After reading all the available studies I could find and studying
all the articles in the newspapers for over 30 years, I find what is most
outstanding is Serial killers were sexually inhibited by their strong
religious upbringing.
Nearly all serial killers are very devou... 阅读全帖
d********h
发帖数: 230
47
来自主题: TrustInJesus版 - Serial Killers vs Christian
http://home.comcast.net/~pobrien48/serial_killers.htm
Serial Killers:
The FBI gave the standard profile of a serial killer, He is a person with
few friends. He became much more religious just before he started murdering
people. After reading all the available studies I could find and studying
all the articles in the newspapers for over 30 years, I find what is most
outstanding is Serial killers were sexually inhibited by their strong
religious upbringing.
Nearly all serial killers are very devou... 阅读全帖
F****n
发帖数: 438
48
来自主题: NKU版 - 几篇期刊文章 (转载)
【 以下文字转载自 Medicalpractice 讨论区 】
发信人: FeiLun (Is Horrible), 信区: Medicalpractice
标 题: 几篇期刊文章
发信站: BBS 未名空间站 (Sat Jul 12 22:36:30 2014, 美东)
那位大侠可以帮组查一下这几篇的全文吗?叩谢。
请发:y******[email protected].
I.
Role of small-conductance calcium-activated potassium channels in atrial
electrophysiology and fibrillation in the dog.
Qi XY1, Diness JG, Brundel BJ, Zhou XB, Naud P, Wu CT, Huang H, Harada M,
Aflaki M, Dobrev D, Grunnet M, Nattel S.
Author information
Abstract
BACKGROUND:
Recent evidence points to functional... 阅读全帖
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