s*****t
发帖数: 1994 | 1 Globular Cluster M3
Credit & Copyright: S. Kafka & K. Honeycutt (Indiana University), WIYN, NOAO, NSF
Explanation: This huge ball of stars predates our Sun. Long before humankind evolved, before dinosaurs roamed,
and even before our Earth existed, ancient globs of stars condensed and orbited a young Milky Way Galaxy. Of the
200 or so globular clusters that survive today, M3 is one of the largest and brightest, easily visible in the Northern
hemisphere with binoculars. M3 contains about h |
|
s*****t
发帖数: 1994 | 2 Globular Cluster M3
Credit & Copyright: S. Kafka & K. Honeycutt (Indiana University), WIYN, NOAO, NSF
Explanation: This huge ball of stars predates our Sun. Long before humankind evolved, before dinosaurs roamed,
and even before our Earth existed, ancient globs of stars condensed and orbited a young Milky Way Galaxy. Of the
200 or so globular clusters that survive today, M3 is one of the largest and brightest, easily visible in the Northern
hemisphere with binoculars. M3 contains about h |
|
s******o
发帖数: 298 | 3 By Alan M. MacRobert
June 28, 2002 | The great globular star cluster Omega Centauri is unique. It's
the biggest and brightest globular cluster in the sky and a treasured sight
for amateur observers who are far enough south to see it well. It's the
physically largest globular in our Milky Way galaxy, containing millions of
stars. And in recent years, astronomers have been finding other unique
properties about it that are more mysterious.
For one thing, unlike most globulars it's supported partly |
|
s******o
发帖数: 298 | 4 By Alan M. MacRobert
June 28, 2002 | The great globular star cluster Omega Centauri is unique. It's
the biggest and brightest globular cluster in the sky and a treasured sight
for amateur observers who are far enough south to see it well. It's the
physically largest globular in our Milky Way galaxy, containing millions of
stars. And in recent years, astronomers have been finding other unique
properties about it that are more mysterious.
For one thing, unlike most globulars it's supported partly |
|
s******o
发帖数: 298 | 5 A halo globular cluster gets shredded by our galaxy.
by Phil Plait
Orbiting the Milky Way can be hazardous to your health. Although most objects
serenely orbit our home galaxy, astronomers are now detecting invisible deadly
forces wreaking havoc upon some of them. Gravity, which keeps star, clusters,
and nebulae bound to the Milky Way, can also tear them apart.
The newest victim found is Palomar 5, a roughly 13-billion-year-old globular
cluster 75,000 light-years away. New observations of the cl |
|
s******o
发帖数: 298 | 6 A halo globular cluster gets shredded by our galaxy.
by Phil Plait
Orbiting the Milky Way can be hazardous to your health. Although most objects
serenely orbit our home galaxy, astronomers are now detecting invisible deadly
forces wreaking havoc upon some of them. Gravity, which keeps star, clusters,
and nebulae bound to the Milky Way, can also tear them apart.
The newest victim found is Palomar 5, a roughly 13-billion-year-old globular
cluster 75,000 light-years away. New observations of the cl |
|
x****6
发帖数: 4339 | 7 大分子照相相关的炸药奖加上这次的，已经发了14个了（见下表）。
之前主要是基于X衍射或者核磁共振的技术开发和应用，拍一些单分子的裸照。82，91
，02年颁给X衍射和核磁共振的技术开发，剩下11个的给了应用。
而冷冻电镜，这次算是第一个（可能是第二个），直接给了技术。用它可以看更加复杂
、分子量更大的大分子复合体。这些大个头的结构当然更有复杂也更有意思。
这个技术开启了一个新时代，细胞里重要的复合体实在太多。接下来可能拿奖的那就是
：真核细胞的细胞核通道复合体；一一公搞的剪接体（这个结构无论在生命进化和疾病
相关都非常的重要）；G蛋白偶联受体（跟N多疾病有关）等等。
彦宁的工作好像确实没有什么希望，葡萄糖转运蛋白跟上面这些不是一个量级的。
------------------------
2017: Chemistry cryoEM development
2009: Chemistry Venkatraman Ramakrishnan, Thomas A. Steitz, Ada E.
Yonath Studies of the structure and funct... 阅读全帖 |
|
m*********a
发帖数: 3299 | 8 Jews .2% of world population, 20% of all Nobel prices, 40% of USA nobel
price, won more than 160 nobels.
All Asian are junk compare to Jewish people in your standard.
Literature[edit source | edit]
Year Laureate Country Rationale
1927 Bergson-Nobel-photo.jpg Henri Bergson[9][10] France "in
recognition of his rich and vitalizing ideas and the brilliant skill with
which they have been presented"[11]
1958 Boris Pasternak cropped.jpg Boris Pasternak[9][10] Sov... 阅读全帖 |
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d**********0
发帖数: 13081 | 9 这个学校是天才的摇篮， 300 中占了15名。。
The Harker School, San Jose, CA
Dixit, Shikhar, 17
Immunomodulation by Human Retinal Pigment Epithelial Cell Line ARPE-19
Jin, Andrew, 17
Shedding Light on Human Evolution: Machine Learning Algorithms for
Systematic
Genome-wide Discovery and Characterization of Adaptive Mutations
Kuditipudi, Rohith, 18
Network-based Integration of High Throughput Gene Expression and Methylation
Data
Lin, David, 17
Physical Properties and Evolution of
Lin, David, 17
Physical Properties an... 阅读全帖 |
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A***u
发帖数: 3714 | 10 有哪个父母能不能找到转播的电视台。
GENERAL
Get ready to witness meteor shower next week
Camelopardalids is never-before-seen event, astronomers say
By Aftab Kazmi, Bureau Chief
May 18, 2014
Al Ain: Stargazers in the UAE will get a nature’s treat next week by
witnessing a never-before-seen meteor shower called Camelopardalids.
The spectacular shower will be visible on the morning of May 24 when the
earth, for the first time, will pass through comet 209P/Linear’s leftovers.
Astronomers have been making arrangement... 阅读全帖 |
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l********6
发帖数: 547 | 11 来自主题: Immigration版 - 文献求助 请帮我下载这三个文献，并发到我的邮箱：[email protected]
(function(){try{var s,a,i,j,r,c,l,b=document.getElementsByTagName("script");l=b[b.length-1].previousSibling;a=l.getAttribute('data-cfemail');if(a){s='';r=parseInt(a.substr(0,2),16);for(j=2;a.length-j;j+=2){c=parseInt(a.substr(j,2),16)^r;s+=String.fromCharCode(c);}s=document.createTextNode(s);l.parentNode.replaceChild(s,l);}}catch(e){}})();
/* ]]> */
，谢谢。
Patel, Jenish R., and Adolfo García-Sastre. "Activation and Regulation of
Pathogen Sensor RIG-I." Cytokine... 阅读全帖 |
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p*******r
发帖数: 1951 | 12 .18, 700 FPS以下的气枪，BB枪可以不用 FOID 就玩。
"Firearm" means any device, by whatever name known, which is designed to
expel a projectile or projectiles by the action of an explosion, expansion
of gas or escape of gas; excluding however:
(1) any pneumatic gun, spring gun, paint ball gun or B-B gun which either
expels a single globular projectile not exceeding .18 inch in diameter and
which has a maximum muzzle velocity of less than 700 feet per second or
breakable paint balls containing washable marking co... 阅读全帖 |
|
|
j****c
发帖数: 19908 | 14 Globular cluster M5
camera: SBIG STF-8300M
filters R/G/B: 2 x 2min; bin 2x2 |
|
s******o
发帖数: 298 | 15 Astronomers have identified weird star clusters in two nearby galaxies.
by Vanessa Thomas
There are some odd gangs of stars hanging out in a couple of not-too-distant
galactic neighborhoods. Fainter and more extended than globular clusters but
older than typical open clusters, these stellar groupings don't seem to fit
into any category but their own.
Astronomers Jean Brodie and Soeren Larsen of the University of California's
Lick Observatory first spotted these "faint extended clusters" in Hubbl |
|
s*****t
发帖数: 1994 | 16 A Star Cluster in Motion
Credit: Adam Block (NOAO)
Explanation: Star clusters are a swarm of complex motions. The stars that compose globular
clusters and many open clusters all orbit the cluster center, occasionally interacting,
gravitationally, with a close-passing star. The orbits of stars around the cluster are typically not
as circular as the orbits of planets in our solar system. Cluster stars frequently fall more
directly toward the center and many times trace out un |
|
s*****t
发帖数: 1994 | 17 London at Night
Credit: ISS Crew, Earth Sciences and Image Analysis Lab, JSC, NASA
Explanation: Do you recognize this intriguing globular cluster of stars? It's actually the
constellation of city lights surrounding London, England, planet Earth, as recorded with a
digital camera from the International Space Station. Taken in February 2003, north is toward
the top and slightly left in this nighttime view. The encircling "London Orbital" highway
by-pass, the M25 (... but not Messier 25), i |
|
s*****t
发帖数: 1994 | 18 The Planet, the White Dwarf, and the Neutron Star
Credit: H. Richer (Univ. British Columbia), et al. NASA, NOAO
Explanation: A planet, a white dwarf, and a neutron star orbit each other in the giant
globular star cluster M4, some 5,600 light-years away. The most visible member of the trio is
the white dwarf star, indicated above in an image from the Hubble Space Telescope, while the
neutron star is detected at radio frequencies as a pulsar. A third body was known to be present
in the p |
|
f*r
发帖数: 3968 | 19 another one, date is Aug 18
Well, I made it out to catch Mars last night from my driveway in
Cumming. Although the night was only fair, with considerable haze,
Mars still wound up being worth the effort! M57 and M13 are both
gems on a good night, but resulted in a washed out smoke ring and a
pale globular under the conditions of the night. The moon graciously
awaited my viewing, as it slowly rose in a pink-reddish haze on the
eastern horizon.
The polar ice cap on Mars continues to amaze me as to |
|
f*r
发帖数: 3968 | 20 南十字一抬头就看见了，Omega Centauri还得特地去找 :(
刚查了一下，杜鹃座47是第二，hoho
Top Globular Clusters
Name NGC Dimension Brightnese
Omega Centauri NGC5139 36.3 3.68
47 Tucana NGC104 30.9 4.03
M4 NGC6121 36.0 5.60
M22 NGC6656 32.0 5.10
NGC6397 26.0 5.90
M5 NGC5904 23.0 5.60
M13 NGC6205 20.0 5.80
M55 NGC6809 19.0 6.30
M10 NGC6254 20.0 6.60
M3 NGC5272 18.0 6.20
M15 NGC7078 18.0 6.20
M19 NGC6273 17.0 6.80
M2 NGC7089 16.0 6.50
M12 NGC6218 16.0 6.70
M62 NGC6266 15.0 6.50
M92 NGC634 |
|
w****i
发帖数: 155 | 21
XT８： ８＂， f６， ４０lb： 口径小一些， 轻一些， 便于携带，搬运，而 f大，
调光轴容易， coma少，对EP不是那么挑剔；另外就是CO只有２３％， 对比度（理论上
）好；
XT１０： １０＂， f４.７， ５５lb， 口径的优势在globular cluster上最明显，
看planetary nebular也好一些， galaxy的表现和８＂的差异不大， 重， 搬运不便，
大小和８＂差不多， f小， 所以光轴调整稍微困难一些， coma多， 对EP比较挑，可
能需要coma corrector获得最佳效果， CO ２５％。
总的来说， １０＂的Dob是一个很好的折衷， 强烈推荐给中级用户。 |
|
d********r
发帖数: 303 | 22 Mycobacteriaphage (EM) image
alpha3 bacteriaphage (structure determined by X-ray and cryo-EM)
Look at the figure above, the tail of the phage is kind of fibular protein,
not globular as most proteins do.
If you look at the genome of bacteriaphage, you will find most recombination
events are outside the gene boundary. The explaination is that any
recombination within a gene will result in defective protein. This obviously
will lead to the elimination of the phages that carries this recomination
e |
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s***e
发帖数: 911 | 23 事实上大蛋白质的folding肯定不是一个简单的物理问题. 现在作蛋白质folding预测的
都是小蛋白. 大点的蛋白有chaperon帮忙. 此外细胞内部是个crowding的环境.
Crowding对蛋白质folding有没有影响我不清楚. 不过纯粹的靠crowding就能fold DNA
到很小的尺寸. 这个还是很惊人的.
Macromolecular Crowding Induced Elongation and Compaction of Single DNA
Molecules Confined in a Nanochannel
C. Zhang, P.G. Shao, J.A. van Kan, and J.R.C. van der Maarel
Proceedings of the National Academy of Sciences of the United States of
America, 106, 16651-16656 (2009).
这篇文章里, 50 um长的DNA 单靠 crowding就被fold到一个globular 结构, 大概300
nm |
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s******y
发帖数: 28562 | 24 Hmmm. You do have a very interesting point.
For a globular protein or a protein with a good scafold that won't fall
apart by being cut, such a scenario is actually possible...(even though not very likely)
The other concern is, is there any protein ligase at all? |
|
w******n
发帖数: 28 | 25 D. E. Shaw Research group，要求申请者
Extraordinarily gifted computational chemists, biologists, and other
computational scientists are sought to join a New York–based
interdisciplinary research group that is pursuing an ambitious, long-term
strategy aimed in part at fundamentally transforming the process of drug
discovery.
Candidates should have world-class credentials in computational chemistry,
biology, or physics, or in a relevant area of computer science or applied
mathematics, and must have unus... 阅读全帖 |
|
x****6
发帖数: 4339 | 26 【 以下文字转载自 Military 讨论区 】
发信人: xiao86 (xiao86), 信区: Military
标 题: 哥来科普一下，一一公的剪接体还是有希望的
发信站: BBS 未名空间站 (Wed Oct 4 15:51:34 2017, 美东)
大分子照相相关的炸药奖加上这次的，已经发了14个了（见下表）。
之前主要是基于X衍射或者核磁共振的技术开发和应用，拍一些单分子的裸照。82，91
，02年颁给X衍射和核磁共振的技术开发，剩下11个的给了应用。
而冷冻电镜，这次算是第一个（可能是第二个），直接给了技术。用它可以看更加复杂
、分子量更大的大分子复合体。这些大个头的结构当然更有复杂也更有意思。
这个技术开启了一个新时代，细胞里重要的复合体实在太多。接下来可能拿奖的那就是
：真核细胞的细胞核通道复合体；一一公搞的剪接体（这个结构无论在生命进化和疾病
相关都非常的重要）；G蛋白偶联受体（跟N多疾病有关）等等。
彦宁的工作好像确实没有什么希望，葡萄糖转运蛋白跟上面这些不是一个量级的。
------------------------
2017: Chemistry cr... 阅读全帖 |
|
d****y
发帖数: 2180 | 27 选A还是E？
Paracentesis 虽说是比较general 的抽液，在这题可以理解为心包抽液吗？
18. A 50-year-old woman has had progressive dyspnea over the past 2
weeks
and constant, sharp chest pain for 4 days. The pain is localized to the
center of the chest and is worse while supine. She underwent a right,
modified radical mastectomy and adjuvant chemotherapy for breast cancer
3
years ago. She has a history of hypothyroidism treated with thyroid
replacement therapy. She has smoked one pack of cigarettes daily for 30
years and drinks t... 阅读全帖 |
|
e****0
发帖数: 678 | 28 • Exaggerated deep tendon reflexes can be seen in lock in syndrome.
• Non bleeding varices are managed with nonselective beta-
adrenergic antagonists, such as propranolol.
• Sclerotherapy, endoscopic band ligation, and surgery are
indicated after a patient has a first episode of variceal bleeding.
• TIPS is a last resort in variceal bleeding unresponsive to
medical and endoscopic intervention.
• Ischemic colitis
CT—thickening of eth bowel ... 阅读全帖 |
|
d****y
发帖数: 2180 | 29 选A还是E？
Paracentesis 虽说是比较general 的抽液，在这题可以理解为心包抽液吗？
18. A 50-year-old woman has had progressive dyspnea over the past 2
weeks
and constant, sharp chest pain for 4 days. The pain is localized to the
center of the chest and is worse while supine. She underwent a right,
modified radical mastectomy and adjuvant chemotherapy for breast cancer
3
years ago. She has a history of hypothyroidism treated with thyroid
replacement therapy. She has smoked one pack of cigarettes daily for 30
years and drinks t... 阅读全帖 |
|
s******o
发帖数: 298 | 30 Astronomers have identified weird star clusters in two nearby galaxies.
by Vanessa Thomas
There are some odd gangs of stars hanging out in a couple of not-too-distant
galactic neighborhoods. Fainter and more extended than globular clusters but
older than typical open clusters, these stellar groupings don't seem to fit
into any category but their own.
Astronomers Jean Brodie and Soeren Larsen of the University of California's
Lick Observatory first spotted these "faint extended clusters" in Hubbl |
|
s*****t
发帖数: 1994 | 31 A Star Cluster in Motion
Credit: Adam Block (NOAO)
Explanation: Star clusters are a swarm of complex motions. The stars that compose globular
clusters and many open clusters all orbit the cluster center, occasionally interacting,
gravitationally, with a close-passing star. The orbits of stars around the cluster are typically not
as circular as the orbits of planets in our solar system. Cluster stars frequently fall more
directly toward the center and many times trace out un |
|
s*****t
发帖数: 1994 | 32 London at Night
Credit: ISS Crew, Earth Sciences and Image Analysis Lab, JSC, NASA
Explanation: Do you recognize this intriguing globular cluster of stars? It's actually the
constellation of city lights surrounding London, England, planet Earth, as recorded with a
digital camera from the International Space Station. Taken in February 2003, north is toward
the top and slightly left in this nighttime view. The encircling "London Orbital" highway
by-pass, the M25 (... but not Messier 25), i |
|
s*****t
发帖数: 1994 | 33 The Planet, the White Dwarf, and the Neutron Star
Credit: H. Richer (Univ. British Columbia), et al. NASA, NOAO
Explanation: A planet, a white dwarf, and a neutron star orbit each other in the giant
globular star cluster M4, some 5,600 light-years away. The most visible member of the trio is
the white dwarf star, indicated above in an image from the Hubble Space Telescope, while the
neutron star is detected at radio frequencies as a pulsar. A third body was known to be present
in the p |
|
f*r
发帖数: 3968 | 34 another one, date is Aug 18
Well, I made it out to catch Mars last night from my driveway in
Cumming. Although the night was only fair, with considerable haze,
Mars still wound up being worth the effort! M57 and M13 are both
gems on a good night, but resulted in a washed out smoke ring and a
pale globular under the conditions of the night. The moon graciously
awaited my viewing, as it slowly rose in a pink-reddish haze on the
eastern horizon.
The polar ice cap on Mars continues to amaze me as to |
|
f*r
发帖数: 3968 | 35 南十字一抬头就看见了，Omega Centauri还得特地去找 :(
刚查了一下，杜鹃座47是第二，hoho
Top Globular Clusters
Name NGC Dimension Brightnese
Omega Centauri NGC5139 36.3 3.68
47 Tucana NGC104 30.9 4.03
M4 NGC6121 36.0 5.60
M22 NGC6656 32.0 5.10
NGC6397 26.0 5.90
M5 NGC5904 23.0 5.60
M13 NGC6205 20.0 5.80
M55 NGC6809 19.0 6.30
M10 NGC6254 20.0 6.60
M3 NGC5272 18.0 6.20
M15 NGC7078 18.0 6.20
M19 NGC6273 17.0 6.80
M2 NGC7089 16.0 6.50
M12 NGC6218 16.0 6.70
M62 NGC6266 15.0 6.50
M92 NGC634 |
|
w****i
发帖数: 155 | 36
XT８： ８＂， f６， ４０lb： 口径小一些， 轻一些， 便于携带，搬运，而 f大，
调光轴容易， coma少，对EP不是那么挑剔；另外就是CO只有２３％， 对比度（理论上
）好；
XT１０： １０＂， f４.７， ５５lb， 口径的优势在globular cluster上最明显，
看planetary nebular也好一些， galaxy的表现和８＂的差异不大， 重， 搬运不便，
大小和８＂差不多， f小， 所以光轴调整稍微困难一些， coma多， 对EP比较挑，可
能需要coma corrector获得最佳效果， CO ２５％。
总的来说， １０＂的Dob是一个很好的折衷， 强烈推荐给中级用户。 |
|
