z*t
发帖数: 863 | 1 Beutler得奖，Medzhitov会不会有意见？
http://www.sciencedirect.com/science/article/pii/S1074761309002
Ruslan Medzhitov
This year marks the 20th anniversary of a publication (Janeway, 1989) that
in many ways revolutionized our understanding of the immune system. As part
of the proceedings of the Cold Spring Harbor Symposium on Immune Recognition
, the paper authored by the late Charles A. Janeway, Jr. was not a standard
peer-reviewed publication. In fact, Charlie used to refer to it as “the
best paper I've ... 阅读全帖 |
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y******8
发帖数: 1764 | 2 I am well aware of the famous evolution story of fly. However, unless human
or ancient apes could be down-sized by 10 fold and their life-cylces
accelerated by 10 fold, the severe chromosome abnormalities could drive the
species extinct when located in a competition-rich environment like south Africa.
In the lab, we can easily find fly strains with huge chromosome deletion/
duplication/inversion but viable and fertile. If the situation happened even
at 10% extent in human genome, the individual ... 阅读全帖 |
|
A********2
发帖数: 107 | 3 Dog and wolf evolve from the same common ancestor but Dogs have been
domesticated by humans for more than 30000 years so many dogs have
deleterious mutations (including chromosomal rearrangements) and they would
have been couterselected without domestication. Do you mean there are
somatic chromosomal rearrangements in Dogs cells compared to Cats?
against |
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z****1
发帖数: 33 | 5 学了。。。而且忘了。:-)
看了楼上的链接，多谢！但是有的地方看不太明白。。。:-(
1)对于常染色体而言，确实是每一代丢失一半遗传信息，是吧？(yes or no?)
2)对于Y染色体而言，全人类一共就那么几条。是吧？(yes or no?)
3)不理解的是：Y-chromosomal Adam的两个儿子跟Y-chromosomal Adam的Y染色体不同(
A and BT)。。。这是什么意思？难道Y染色体不是在家族里不变的吗？ |
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l**********1
发帖数: 5204 | 6 Still you can try HAC Human artificial chromosome not BAC bacterial artificial chromosome
with that mice gene with labeled YFP knock in HAC
then expressed in Human kidney cells.
please refer:
//www.ncbi.nlm.nih.gov/pubmed/21750534
RE:
>如果你得是一个下游基因，那么多半不表
[回复]
发信人: amysf (kdfa), 信区: Biology
标 题: Re: 请教鼠基因在人细胞的表达
发信站: BBS 未名空间站 (Thu Feb 9 10:03:15 2012, 美东)
...
My gene is about 2500 aa. I used in kidney cells.
----------- |
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s**********t
发帖数: 680 | 7 Journal of Theoretical Biology
Volume 141, Issue 1, 8 November 1989, Pages 117–136
Title: A fractal model of chromosomes and chromosomal DNA replication
Author: Manabu Takahashi
Link:
http://dx.doi.org/10.1016/S0022-5193(89)80012-8
Thank you very much for your help!
Please send it to: b************[email protected]
Thanks!!! |
|
i***r
发帖数: 1035 | 8 举个例子：
数据B：已发表的我们发现的SNPs，大概这样（chromosome，位点，和SNPs，其余省略）
chr1 1240 *** C
chr1 1270 *** T
数据A：最新的测序数据，大概这样（chromosome，序列起点，末点，CIGAR，序列，其
余略）
chr1 1234 1279 * * * 20M5D20M AAAAACCCCCCTTTTTGGGGGAAAAACCCCCTTTTTGGGGG
任务
1)确定A序列包含了B里面的SNP（两个SNPs都在1234-1279的区间，是我要的）
2）进一步根据序列，找出对应位点的base
example 1 是在第6个（1240-1234=6）base上，那么是C
example 2 是在第36个（1270-1234=36）base上，根据CIGAR code，有5个deletion，
股序列应该是：
AAAAACCCCCCTTTTTGGGGG*****AAAAACCCCCTTTTTGGGGG
那么应该是也是T
我现在就是有数据A和B，需要有软件能够：自动比较区间，同时根据CIGAR code找出对
应的base ... 阅读全帖 |
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l**********1
发帖数: 5204 | 9 Re LZ
pls go to
one RNA-seq blog
one topic:
Long noncoding RNAs in pathogenesis
web link:
http://www.rna-seqblog.com/
LncRNAs (pronounced “link”) are long non-coding RNAs that are emerging as
important regulators of gene expression in biological processes and diseases
. In this issue of the Journal of Clinical Investigation, two papers connect
lncRNAs to inherited conditions in humans.
Sylvia B-hring and colleagues at the Experimental and Clinical Research
Center in Berlin found a chromosomal ... 阅读全帖 |
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m******g
发帖数: 467 | 10 Science 14.01.03
新年快乐！P.S. 这周又没有遇到“推荐”的paper。
稍微了解一下：
1. Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction
in the Mouse
另外，
complex and multilayered palindromic structure of the Y chromosome
may facilitate internal pairing of nucleotide bases
2. Break-Induced Replication Repair of Damaged Forks Induces Genomic
Duplications in Human Cells
小知识：
1. A Cascade of Histone Modifications Induces Chromatin Condensation in
Mitosis
2. A Neural Mechanism Underlying Mating Preference... 阅读全帖 |
|
m******g
发帖数: 467 | 11 Science 14.01.03
新年快乐！P.S. 这周又没有遇到“推荐”的paper。
稍微了解一下：
1. Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction
in the Mouse
另外，
complex and multilayered palindromic structure of the Y chromosome
may facilitate internal pairing of nucleotide bases
2. Break-Induced Replication Repair of Damaged Forks Induces Genomic
Duplications in Human Cells
小知识：
1. A Cascade of Histone Modifications Induces Chromatin Condensation in
Mitosis
2. A Neural Mechanism Underlying Mating Preference... 阅读全帖 |
|
m******g
发帖数: 467 | 12 Nature 14.03.06
稍微了解一下：
1. A predictive fitness model for influenza
2. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
a short trinucleotide protospacer adjacent motif (PAM)
3. Cell-autonomous correction of ring chromosomes in human induced
pluripotent stem cells
lost the abnormal chromosome and duplicated the wild-type homologue
through the compensatory uniparental disomy
小知识：
1. Genes make bacteria magnetic
2. Worms bond to reach new heights
towers with up to 1,000 individuals, r... 阅读全帖 |
|
m******g
发帖数: 467 | 13 Science 14.04.04
推荐：
1. Designer Chromosome
Total Synthesis of a Functional Designer Eukaryotic Chromosome
稍微了解一下：
1. Many individual stories for scientists
2. Designer Embryo
Construction of a Vertebrate Embryo from Two Opposing Morphogen Gradients
Nodal and BMP in Zebrafish
小知识：
1. Engineering Larger DNA Structures
Polyhedra Self-Assembled from DNA Tripods and Characterized with 3D DNA-
PAINT |
|
D*a
发帖数: 6830 | 14 “老鼠在这个基因敲除后，端粒长度没有变化，没有其他任何表型。”
“老鼠端粒长度突然短”
你在逗我？？
http://www.cell.com/cell/abstract/S0092-8674%2801%2980006-4
摘要：mTR-/- mice lacked detectable telomerase activity yet were viable for
the six generations analyzed. ...Telomeres were shown to shorten at a rate
of 4.8 +/- 2.4 kb per mTR-/- generation. Cells from the fourth mTR-/-
generation onward pos- sessed chromosome ends lacking detectable telo- mere
repeats, aneuploidy, and chromosomal abnor- malities, including end-to-end
fusions.
这是最原始的文献，
下... 阅读全帖 |
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l*********y
发帖数: 12 | 15 How many pups have you screened? What are the genotypes of the parents? If
the gene is X chromosome linked you will be able to see only one band in
male pups, either wt or floxed, depending on the genotypes of the parental
animals. So first check if your gene is located on X chromosome, and screen
more female pups.
Good luck! |
|
s*****i
发帖数: 315 | 16 请问能否举例一些基因？
微核可能是由lagging chromosome形成的，有丝分裂后期的时候有的chroomosome没能
跟大部队形成新核，于是自己形成了一个微核。
微核内可能有大量dna复制的问题，导致chromosome thripsis
但是微核内的 dsb signal可能跟核内的不同，微核的核膜是否完整也是未知的
★ 发自iPhone App: ChineseWeb 8.7 |
|
d*****3
发帖数: 167 | 17 现在在做试管婴儿。做了染色体胚胎检查。 结果是有一个胚胎、是六号染色体的
第24个点位缺失：
46, XY, del(6)(p24)
用的是NGS的技术做的Comprehensive Chromosome Screening (CCS)。这个点位的缺失
是致病的。 我的理解是如果是整条染色体缺失，是非常容易查出来的。但是越是小段
的缺失，越考验技术。却容易活产。 如果是正常怀孕做绒毛穿刺，这样的缺失能查出
来吗？绒毛或是羊水穿刺是用的CMA技术，这个技术能有多高的resolution?比如一个是
六号染色体的第24个点位缺失是治病的。这个如果是自然怀孕做绒穿能查出吗？NGS是
相对新的科技。 一般大医院还不用。 在产检中用的是Prenatal Chromosomal
Microarray Analysis. 这个技术的resolution 能达到什么程度？能检查出比如六号染
色体的短臂第24个点位缺失吗？
有没有产前诊断（CVS)当中用NGS技术的？NGS的好处是resolution更高还是便宜？ |
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n**e
发帖数: 2026 | 18 【 以下文字转载自 WaterWorld 讨论区 】
发信人: nile (nile), 信区: WaterWorld
标 题: 美国科学促进会《科学》大旗下的转基因谎言
发信站: BBS 未名空间站 (Fri Oct 30 10:18:45 2015, 美东)
今年初，美国科学促进会（AAAS）和皮尤研究中心（Pew Research Center）联合公布
的一项调查显示，88％的科学家认为转基因食品可安全食用，持这一看法的公众只有37
％。报告认为差距如此之大的一个可能原因是，三分之二的公众认为科学家对转基因食
品的健康后果没有清晰认识。这就是真正的原因吗？
根据报告全文，皮尤中心给19，984名科学家发出了调查问卷，3748人（18.8%）完成了
问卷调查。其中生物医学学科背景的科学家占50%。报告没有说明50%的生物医学背景是
否能够代表科学家总体的学科构成。更大问题是在这50%的科学家人群中，有多少人的
工作是与转基因作物的研究有关，以什么样的方式相关。报告没有提供任何信息。
由于这些关键信息缺失，88%的科学家相信转基因安全的说法毫无意义。在一个没有代
表性并且无法排除... 阅读全帖 |
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m****e
发帖数: 489 | 19 Prenat Diagn. 2016 Feb 2. doi: 10.1002/pd.4782. [Epub ahead of print]
Identification of copy number variations associated with congenital heart
disease by chromosomal microarray analysis and next generation sequencing.
Zhu X1, Li J1, Ru T1, Wang Y2, Xu Y1, Yang Y1, Wu X1, Cram DS3, Hu Y1.
Author information
Zhonghua Fu Chan Ke Za Zhi. 2014 Dec;49(12):893-8.
[Clinical value of genome-wide high resolution chromosomal microarray
analysis in etiological study of fetuses with congenital heart defects... 阅读全帖 |
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r******g
发帖数: 600 | 20 我自己从来没试过，我问过我老板完全相同的问题
我记得我老板跟我说，gene A and B 在同一个chromosome上面的话，比较难cross
一般情况下，大家都会放弃，选择cross A 和 C, 比如 C gene是B的receptor，这样可
以解释同样的问题
如果A,B 在chromosome上面距离比较远，有可能 重组 成功，但是 需要一定的工作量
如果A,B的gene位置比较近，举个例子，P38MAPK的alpha, beta （MAPK 11,12,13,14）
。。。。 他们隔得非常近 位于同一个locus，所以 一直没有很好的triple KO, quart
KO model
所以说，crispr很强大呀！ |
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s********9
发帖数: 132 | 21 Thanks for the reply.
But in pratice, if one has to do this. What I can think of are:
1) as you said, hoping the homologous recombination during meiosis.
2) get a B+/- allele in A+/- background? 50% chance it would be on the same
chromosome.
Just don't know what people actually do in reality.
BTW, one pertinent questtion, when one makes transgenic mouse, is it routine
to pinpoint the integration site? (People often cross a transgenic mouse
with a KO mouse or transgenic mouse)
Especially for Cre-... 阅读全帖 |
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s********9
发帖数: 132 | 22 I simply brought this up out of curiosity for discussion. I have NO hands-on
experience with mouse genetics whatsoever.
For double KO. the chance gene A and B on the same chromosome would be 1/20.
People have done so many double KO. I figure this could be a practical issue.
For crossing CRE-transgenic mouse with LoxP mouse to produce tissue-specific
KO.
The chance are also 1/20 the CRE-transgene and your LoxP-cassette being on
the same chromosome.
I don't think it's necessary impossible to achie... 阅读全帖 |
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H****N
发帖数: 997 | 23 You point regarding cre transgene and the floxed gene to be knocked out on
the same chromosome is interesting. This can be a problem in practice.
People don't always map the transgene. However, if you have a hard time
getting the flox/flox;cre mouse, it is likely due to that the transgene and
the gene of interest are closely located on the same chromosome.Of course,
you still need to rule out embryonic lethality first.
same
routine
kinds |
|
w****e
发帖数: 93 | 24 高龄产妇35+。先做了maternity T21 plus正常。觉得不放心，在18周时做了一个羊穿
，自己掏腰包加选了microarray 。 普通的羊穿结果没问题，但是microarray 发现了X
(xp22.33)和Y (Yp11.23)染色体PAR1 (pseudoautosomal) 区
上多了一小块, 大小大约0.31M。X,Y染色体的PAR1是SHOX 基因，这个基因的扩增是引
起矮小症ISS (Idiopathic short stature ) 和LWD (软骨生成障碍）的原因。但正常
身高人的染色体里也会发现有这种扩增。
报告说我本人也有这个染色体增扩，所以这个增扩是遗传我的，不是孩子原生的。我的
情况是，身高不高但也算正常158cm，孩子他爹172cm. 小时候爸妈是说过我有好动症，
腿脚没劲，走走就瘫了，但大了也没有什么大问题，除了人容易疲劳之外，还算健康。
Genetic counselor问了我家族的身高，然后就说我是家族型矮小，说这个孩子以后很
可能个子不高，但也不至于不正常。她还说这个是染色体增扩（Gain) 不是缺失（
deletion), 不是那么糟... 阅读全帖 |
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b******k
发帖数: 2321 | 25 Faculty and Postdoctoral Positions at the Life Sciences Institute, Zhejiang
University
The Institute
The Life Sciences Institute of Zhejiang University (LSI-ZJU) was founded in
2009. Dr. Xin-Hua Feng was appointed as the founding director and Dr. Kun-
Liang Guan as the co-director. Located in the scenic city of Hangzhou, LSI
is now a world’s leading center of biological and biomedical research in
China.
As the first special academic zone of ZJU, LSI runs its own graduate program
and enjoys unpar... 阅读全帖 |
|
a******r
发帖数: 786 | 26 cancer cell 会自己分化成不同的subpopulation， 也会有mitosis non-disjunction.
很多时候养着养着就出现copy number variation， 有的细胞有好几个copy 的
chromosome， 比如说glioma 里有血细胞能长到4-6个 chromosome 7. 但是有的缺保持
2 copy。 |
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K**********n
发帖数: 1197 | 27 学术界珍稀有限的原版外文资料，
Remote Mind Control Technology
Reprinted from SECRET AND SUPPRESSED: BANNED IDEAS AND HIDDEN
HISTORY, edited by Jim Keith, $12.95, available from
1-800-680-INET.
There had been an ongoing controversy over health effects of electromagnetic
fields (EMF) for years (e.g., extremely low frequency radiation and the
Navy's Project Seafarer; emissions of high power lines and video display
terminals; radar and other military and industrial sources of radio
frequencies and micr... 阅读全帖 |
|
w**d
发帖数: 362 | 28 做OB的练习题，有道题很有意思。
Question 7:
Many couples attempt to influence the gender of the child they are trying to
conceive by using special sexual positions, eating special food, or having
intercourse at specific times. None of these are factors in the
determination of the gender of the conceptus. What has research shown about
gender determination?
You selected: There is a 50-50 chance of having a male or a female
Correct
Explanation:
Sex determination occurs at the time of fertilization based ... 阅读全帖 |
|
d***g
发帖数: 9 | 29 很多年轻人到美国都想要申请大学的护士专业，也就是英文所说的Nursing，因为几乎
每个人都说护士可以在美国申请到绿卡，可以赚年薪起薪6万，那为什么有人说简单，
有人说复杂，这其中究竟有什么诀窍呢？
那么下面整个介绍一下在美国做护士的步骤，以及申请绿卡的条件。
这篇文章会介绍几个部分的内容，
包括：
1 申请护士职业移民最基本的条件和优点。
2国内护士专业毕业，人在美国，或人不在美国，如何申请美国大学的护士专业或申请
护士执照考试和如何进行职业规划。
3国内高中毕业，有高中毕业文凭，人在美国，如何申请美国大学的护士专业。
4国内大专或本科毕业（非护士专业），有高中和大学文凭，如何申请美国大学的护士
专业。
5 已经有身份（有绿卡或是美国公民），但是想申请护士专业，如何申请美国大学的护
士专业。
6 通过考试后，取得美国护士执照，通过托福考试后，如何找医院面试谈判，如何找律
师递交移民申请，如何关注职业移民配额，最终申请绿卡。
7 注册护士考试的英文名称和考试内容，那里可以买参考书，网上有哪些资源。
8 申请过程中常见的困难和困扰有那些
9 托福考试的复习与报考准备
10 附录 护士注册... 阅读全帖 |
|
b********e
发帖数: 41 | 30 Now this is a social problem, a girl's son doesn't carry the y part of the
girl's father's sex chromosome, but he does carry some part of the girl's
father's other chromosomes. Then what is a descent?
Who knows. |
|
o*****c
发帖数: 7 | 31 http://www.msnbc.com/news/928246.asp?0cv=HB10
Scientists have discovered that the Y chromosome uses a neat trick to repair
its most crucial genes, a strategy that apparently helps keep it from rotting
away over evolutionary time. The finding is the result of the first
comprehensive and detailed analysis of the genetic code of the Y chromosome,
which is best known for supplying the biological signal to make males rather
than females.
is |
|
s**********t
发帖数: 680 | 32 Journal of Theoretical Biology
Volume 141, Issue 1, 8 November 1989, Pages 117–136
Title: A fractal model of chromosomes and chromosomal DNA replication
Author: Manabu Takahashi
Link:
http://dx.doi.org/10.1016/S0022-5193(89)80012-8
Thank you very much for your help!
Please send it to: b************[email protected]
Thanks!!! |
|
P*********t
发帖数: 4451 | 33 【 以下文字转载自 NewJersey 讨论区 】
发信人: PhuqCaliCat (山里人 Schulanfang), 信区: NewJersey
标 题: Nobel Prize in Medicine
发信站: BBS 未名空间站 (Mon Oct 5 11:25:11 2009, 美东)
From Bloomberg.com:
"...
Their research explored a fundamental question of life: how
chromosomes that carry the genetic code in DNA are copied in
their entirety each time a cell divides. The key is the end of
the chromosome, where caps known as telomeres reside. An enzyme
discovered by the researchers, dubbed telomerase, prevents the
end from be |
|
e****o
发帖数: 268 | 34 Press Release
5 October 2009
The Nobel Assembly at Karolinska Institutet has today decided to award
The Nobel Prize in Physiology or Medicine 2009 jointly to
Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak
for the discovery of
"how chromosomes are protected by telomeres and the enzyme telomerase"
Summary
This year's Nobel Prize in Physiology or Medicine is awarded to three
scientists who have solved a major problem in biology: how the chromosomes
can be copied in a complete way duri |
|
O*******d
发帖数: 20343 | 35 你显然是生物外行，科盲。难怪那么幼稚。 要攻击进化论，先把进化论的理论搞清楚
了再发言。
1. Archidiacono, N., Storlazzi, C.T., Spalluto, C., Ricco, A.S., Marzella
, R., Rocchi, M. 1998. ‘Evolution of chromosome Y in primates.’ Chromosoma
107:241-246.
2. Britten, R.J. 2002. ‘Divergence between samples of chimpanzee and
human DNA sequences is 5% counting indels.’ Proceedings National Academy
Science 99:13633-13635.
3. Fujiyama, A., Watanabe, H., Toyoda, A., Taylor, T.D., Itoh, T., Tsai,
S.F., Park, H.S., Yaspo, M.L., Lehrach, H., C... 阅读全帖 |
|
b**h
发帖数: 293 | 36 【 以下文字转载自 WaterWorld 讨论区 】
发信人: twistberry (twistberry), 信区: WaterWorld
标 题: 言论要公正，不要凡事都怨GCD
发信站: BBS 未名空间站 (Sun Feb 27 01:54:37 2011, 美东)
虽然我对薄陈那一对没有好感，也不认为GCD有多伟大，但是看到有些人因为这一对
在哈佛上学就辱骂GCD，也常看到有些人把很多不相干的事也算在GCD头上，要说三点：
1）这个世界本来就他妈的不公平。
克林顿的女儿先后进过斯坦福，牛津，哥伦比亚，和她老爸没关系？ 克林顿挣的钱每
一分都光明公正？
英国皇室那两崽子做了啥？戴安娜中学成绩全班倒数几名，连基本加减法的心算能力都
没有。儿子的X chromosome都从她那里来的，如果生于普通人家可能找个像样的工作都
不容易。可是英国万民还对他们崇拜爱慕呢！英国皇室的费用，全民分担。
这种不公平在没有GCD执政的地方到处都是，不要看到不公平就说是GCD造成的。
２）中国近一两百年的近代史充满血泪， 民不聊生， 还被称作东亚病夫。
鸦片战争失败赔款割地，中国人饥寒交迫的时... 阅读全帖 |
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a****t
发帖数: 7049 | 38 我上面贴连接了。
Abstract
The prehistoric peopling of East Asia by modern humans remains controversial
with respect to early population migrations. Here, we present a systematic
sampling and genetic screening of an East Asian–specific Y-chromosome
haplogroup (O3-M122) in 2,332 individuals from diverse East Asian
populations. Our results indicate that the O3-M122 lineage is dominant in
East Asian populations, with an average frequency of 44.3%. The
microsatellite data show that the O3-M122 haplotypes in |
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K*******i
发帖数: 631 | 39 扯淡，匈奴突厥蒙古一脉相承，都是C系人，司马迁也被匈奴人忽悠了
http://onlinelibrary.wiley.com/doi/10.1002/ajpa.20429/abstract
In the present study, nuclear (autosomal and Y-chromosome short tandem
repeats) and mitochondrial (hypervariable region I) ancient DNA data
previously obtained from a 2,300-year-old Xiongnu population。。。
。。。 This result supports the hypothesis that the succession over time of
different Turkic and Mongolian tribes in the current territory of Mongolia
resulted in cultural rather than genetic exchanges. |
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K*******i
发帖数: 631 | 40 看文献，在配合我的宝图：
匈奴突厥蒙古一脉相承，所以主体都是C系人，司马迁也被匈奴人忽悠了
http://onlinelibrary.wiley.com/doi/10.1002/ajpa.20429/abstract
In the present study, nuclear (autosomal and Y-chromosome short tandem
repeats) and mitochondrial (hypervariable region I) ancient DNA data
previously obtained from a 2,300-year-old Xiongnu population。。。
。。。 This result supports the hypothesis that the succession over time of
different Turkic and Mongolian tribes in the current territory of Mongolia
resulted in cultural rather than geneti... 阅读全帖 |
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S*******C
发帖数: 7325 | 41 ☆─────────────────────────────────────☆
aptget (apt) 于 (Tue Jul 27 23:27:24 2010, 美东) 提到:
二楼
☆─────────────────────────────────────☆
aptget (apt) 于 (Tue Jul 27 23:39:10 2010, 美东) 提到:
黄的是通用语，绿的也是汉语，其他颜色的不是
修改了一下的新版本：
http://tinyurl.com/23d42vv
附件里是老版本：
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daigaku (๑۩۞۩๑) 于 (Wed Jul 28 00:01:09 2010, 美东) 提到:
你那个“北语”是从哪冒出来的啊
☆─────────────────────────────────────☆
aptget (apt) 于 (Wed Jul 28 00:08:33 2010, 美东) 提到... 阅读全帖 |
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c**i
发帖数: 6973 | 42 Nicholas Wade, Finding on Finding on Dialects Casts New Light on the Origins
of the Japanese People. New York Times, May 4, 2011
http://www.nytimes.com/2011/05/04/world
/asia/04language.html?scp=1&sq=japan%20dialects&st=cse
(Japanese "language is descended from that of the rice-growing farmers who
arrived in Japan from the Korean Peninsula, and not from the hunter-
gatherers who first inhabited the islands some 30,000 years ago")
My comment:
(a)
(i) Jōmon period
http://en.wikipedia.org/wiki/J%C5... 阅读全帖 |
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R*****d
发帖数: 1148 | 45 是的。目前对于长城以南，新石器-青铜时代的中国古人的基因检测，已经有所结果，
虽然并不十分全面。这是2007年发表在Human Genetics上的复旦的论文（就是国内“分
子人类学”爱好者们熟知的金力李辉等人），Y chromosomes of prehistoric people
along the Yangtze River：
http://www.springerlink.com/content/f1234473n7261m8w/
全文可在此处下载，不过这个网站貌似是非官方的，呵呵：
http://comonca.org.cn/lh/Doc/A37.pdf
研究者们检测了中国境内，特别是长江中下游地区，在现有的古人类文化遗址上挖掘到
的，56件分属不同个体的古人类遗骨的Y染色体谱系。附图可以说是对此论文成果的简
洁概括。从图中我们可以看出，位于山西境内的，属于龙山文化范畴，距今约为四千年
的陶寺遗址，其被分析样品全部属于东亚本土的O系，而且均为当今中国密度最高的O3
。对于长江流域的古人类（其实不能叫“古人类”了，应该叫“古人”，他们很可能就
是我们的祖先，你看吴城文化已经位于... 阅读全帖 |
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l*****e
发帖数: 416 | 46 First, you are misleading. Haplogroup Q may be one of the most widely
distributed Y-chromosome lineages in the modern world, it has been found
everywhere except sub-Sahara Africa. It is quite normal to find a little Q
in both Egyptian and Chinese.
Second, the so-called "one proposal of the Egyptian Theory" is wrong. Q1a1,
which is the only Q sub-group prevailing in Han and Hui Chinese, is
restricted to East Asia. Q sub-groups found in North Africa are either Q1a2
or Q1a3. These three sub-groups ... 阅读全帖 |
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w***b
发帖数: 34 | 47 > 还有80%的概率没有混入外姓
This example can not prove or disprove the assumption that 90% of the
descendant is the true descendant. When you live in a village where almost
everyone has the same Y, no matter how high the adultery rate is, you will
have a high percentage of the next generation with the correct Y chromosome.
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M****7
发帖数: 2334 | 48 "Analyses of this individual's DNA showed that the Tianyuan human shared a
common origin with the ancestors of many present-day Asians and Native
Americans."
Just curious: how many types of Y chromosomes an "individual" can have? I am
asking about the "individual' whose DNA was studied in the report.
Thanks for providing knowledge.
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M****7
发帖数: 2334 | 49 "Analyses of this individual's DNA showed that the Tianyuan human shared a
common origin with the ancestors of many present-day Asians and Native
Americans."
Just curious: how many types of Y chromosomes an "individual" can have? I am
asking about the "individual' whose DNA was studied in the report.
Thanks for providing knowledge.
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f*******2
发帖数: 410 | 50 转载：殷墟的线粒体DNA出来了
http://meeting.physanth.org/program/2013/session13/zeng-2013-pr
只是会议论文。写正式文章还是漫长过程
Preliminary Research on Hereditary Features of Yinxu Population
WEN ZENG1,4, JIAWEI LI2, HONGBIN YUE3, HUI ZHOU2,4 and HONG ZHU1,4.
1College of Humanities, Jilin University, 2College of Life Science, Jilin
University, 3Institute of Archaeology, CASS, 4Research Center for Chinese
Frontier Archaeology, Jilin University
Thursday All day, Park Concourse
Yinxu was the capital during the last phase of th... 阅读全帖 |
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