A********e
发帖数: 354 | 1 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
c********n
发帖数: 1964 | 2 “Chromosomes can be divided into two types—autosomes, and sex chromosomes. Certain genetic traits are linked to your sex, and are passed on through the sex chromosomes. The autosomes contain the rest of the genetic hereditary information. All act in the same way during cell division. Human cells have 23 pairs of large linear nuclear chromosomes, (22 pairs of autosomes and one pair of sex chromosomes) giving a total of 46 per cell.“
我不是学生物的啦。上文(wikipedia里的)看起来23对chromosomes里边只有一对是sex chromosome w... 阅读全帖 |
|
c*******u
发帖数: 12899 | 3 ☆─────────────────────────────────────☆
karo (karo) 于 (Fri Mar 4 12:21:45 2011, 美东) 提到:
看到这样一篇文章，不知道有没有道理啊？如果是真的，我太伤心了，因为我们家都是
男宝宝，本来指望聪明的爸爸能把智商遗传给他们，现在我这个笨妈不是要害惨我的宝
宝们了。55
http://zhidao.baidu.com/question/5021375
智商的遗传基因ZT
满有意思的^^
据说决定智商的八对基因全部都是位于X 染色体上面，然后男生是XY，
X 是来自母亲，
Y 是来自父亲。
所以男生的智商全部都是来自母亲的遗传。
然后女生是X X，所以女生的智商是父亲跟母亲各有一半影响。
然后说，因为女生的智商是父亲母亲都有影响，所以会有中和的效应。
所以女生智商的分布会呈现自然分布( normaldistribution )，就是倒钟状，中间最
多，两边较少。
然后男生因为是完全只受一方影响，所以男生智商分布会呈现在偏向在两个极端。
也就是说，男生天才比较多，但是同时，蠢材之中也是男生特别多。
这个故... 阅读全帖 |
|
p*******g
发帖数: 2976 | 4 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
O***n
发帖数: 13127 | 5 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
a********k
发帖数: 2273 | 6 花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branches in lamellipodia. Cell. 2008 Sep
5;134(5):828-42. PubMed PMID: 18775315; PubMed Central PMCID: PMC2570342.
Cai L, Makhov AM, Bear JE. F-actin... 阅读全帖 |
|
p*******g
发帖数: 2976 | 7 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
|
d****y
发帖数: 2180 | 8 鱼鳞病英文是：Ichthyosis vulgaris
Ichthyosis vulgaris (also known as "Autosomal dominant ichthyosis,"[1]
and "
Ichthyosis simplex"[1]) is a skin disorder causing dry, scaly skin. It
is
the most common form of ichthyosis,[2]:486 affecting around 1 in 250
people.
[3] For this reason it is known as common ichthyosis. It is usually an
autosomal dominant inherited disease (often associated with filaggrin),
although a rare non-heritable version called acquired ichthyosis exists.
It is generally considered to... 阅读全帖 |
|
w******y
发帖数: 4871 | 9 Febrile seizures
Author
Marvin A Fishman, MD
Section Editor
Douglas R Nordli, Jr, MD
Deputy Editor
Janet L Wilterdink, MD
Last literature review version 19.1: January 2011 | This topic last updated:
February 3, 2011 (More)
INTRODUCTION — Febrile seizures are a common cause of convulsions in young
children. They occur in 2 to 4 percent of children younger than five years
of age, but the incidence is as high as 15 percent in some populations. This
incidence has been attributed to closer living arr... 阅读全帖 |
|
D*********n
发帖数: 279 | 10 http://en.wikipedia.org/wiki/Native_Americans_in_the_United_Sta
Native Americans in the United States
From Wikipedia, the free encyclopedia
Jump to: navigation, search
"American Indian" redirects here. For other indigenous peoples, see
Indigenous peoples of the Americas and other geographic regions. For
Americans from South Asia, see Indian American.
This article may be too long to read and navigate comfortably. Please
consider splitting content into sub-articles and/or condensing it. (January
2... 阅读全帖 |
|
T**********e
发帖数: 29576 | 11 4w-8w年前泥人和人类大量混合交配，现代欧亚人保留了1%以上的泥人基因，以中国北京
汉族人保留了1.4%为世界最多，平均略高于中国南方汉人。最后泥人很可能融入现代人
种继而消失。
How Neanderthal DNA Changed Humans
------
The researchers analyzed genetic variants in 846 people of non-African
heritage, 176 people from sub-Saharan Africa and a 50,000-year-old
Neanderthal.
The clearest indicator that a gene variant came from a Neanderthal was if
the variant appeared in some non-Africans and the Neanderthal, but not in
the sub-Saharan Africans.
Levels of Neanderthal ancestry differ in E... 阅读全帖 |
|
l**********1
发帖数: 5204 | 12 Before NGS 2.0 or 3.0 Illumina platform can read enough longer different
isoforms within Exome sequencing and systems biology aspect,
it is still elusive to answer the linkage between SNP2.0 or 3.0 alternative
splicing with
syndromic disease...
Pls check,
>Although previously described in TS, no CACNA1C mutations have been
reported for
>non-syndromic LQTS. With our functional studies confirming Cav1.2 gain-of-
function as the cellular basis for the CACNA1C mutation-positive patient’s
LQTS pheno... 阅读全帖 |
|
l**********1
发帖数: 5204 | 13 Before NGS 2.0 or 3.0 Illumina platform can read enough longer different
isoforms within Exome sequencing and systems biology aspect,
it is still elusive to answer the linkage between SNP2.0 or 3.0 alternative
splicing with
syndromic disease...
Pls check,
>Although previously described in TS, no CACNA1C mutations have been
reported for
>non-syndromic LQTS. With our functional studies confirming Cav1.2 gain-of-
function as the cellular basis for the CACNA1C mutation-positive patient’s
LQTS pheno... 阅读全帖 |
|
n******7
发帖数: 12463 | 14 不是
这是说，本来女性有两个Ｘ，男性有一个Ｘ，所以女性里面有个Ｘ是没有活性的，来保
证男女都只有一个Ｘ激活
但是这个区域在Ｘ Ｙ染色体上都有，所以不管男女都有两个copy
所以既不需要，实际上也没有失活
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435358/
THE X AND Y CHROMOSOMES
The human sex chromosomes (X and Y) originate from an ancestral homologous
chromosome pair, which during mammalian evolution lost homology due to
progressive degradation of the Y chromosome [1]. The X-chromosome in
placental mammals represents approximately 5% of the haploid genome and the
gene content is almost complet... 阅读全帖 |
|
d****y
发帖数: 2180 | 15 Go see the genetic counselor and run some genetic tests. The counselor
then
will tell you which type of disease your husband has and the chance of
inheritance, you will also discuss If there any ways to hElp you have
healthy
children. Good luck! Btw, if it is x- link disease, then
all your children won't have the disease, the girls will be
carriers, the boys will totally be normal ( from the info you provided,
which indicAte that's a x- link recessive disease .)
if it's the autosoma... 阅读全帖 |
|
d******a
发帖数: 32122 | 16 狐狸和狗没法杂交
相差太大，都不是一个亚科的
能跟狗杂交的，只有狼 澳大利亚野狗 金豺 非洲三色犬（无实例）豺狗（无实例）
都有７８条染色体
从图上可以看出，狗和大灰狼是同一种动物，图上跟他们最近的是郊狼，然后依次是金
豺，埃塞俄比亚狼（应该也是种豺），豺狗和三色犬。
而黑背豺和侧纹豺有７４条，即便杂交，也会类似马（６４）和驴（６２）。
狐狸只有30多条
http://2.bp.blogspot.com/-PV8froOj_7U/TjkUecXRk9I/AAAAAAAACmY/vo18yeLfFpo/s1600/canid_phylogeny.jpg
A List of Number of Chromosomes of Various Organisms
African Wild Dog 78
Alfalfa 16
Algae 148
Amoeba 13
American Badger 32
American Marten 38
American Mink 30
Aulacantha (protozoa) 1600 [highest]
Arabidopsis thaliana 10
B... 阅读全帖 |
|
O*******d
发帖数: 20343 | 17 你显然是生物外行，科盲。难怪那么幼稚。 要攻击进化论，先把进化论的理论搞清楚
了再发言。
1. Archidiacono, N., Storlazzi, C.T., Spalluto, C., Ricco, A.S., Marzella
, R., Rocchi, M. 1998. ‘Evolution of chromosome Y in primates.’ Chromosoma
107:241-246.
2. Britten, R.J. 2002. ‘Divergence between samples of chimpanzee and
human DNA sequences is 5% counting indels.’ Proceedings National Academy
Science 99:13633-13635.
3. Fujiyama, A., Watanabe, H., Toyoda, A., Taylor, T.D., Itoh, T., Tsai,
S.F., Park, H.S., Yaspo, M.L., Lehrach, H., C... 阅读全帖 |
|
K*******i
发帖数: 631 | 18 扯淡，匈奴突厥蒙古一脉相承，都是C系人，司马迁也被匈奴人忽悠了
http://onlinelibrary.wiley.com/doi/10.1002/ajpa.20429/abstract
In the present study, nuclear (autosomal and Y-chromosome short tandem
repeats) and mitochondrial (hypervariable region I) ancient DNA data
previously obtained from a 2,300-year-old Xiongnu population。。。
。。。 This result supports the hypothesis that the succession over time of
different Turkic and Mongolian tribes in the current territory of Mongolia
resulted in cultural rather than genetic exchanges. |
|
K*******i
发帖数: 631 | 19 看文献，在配合我的宝图：
匈奴突厥蒙古一脉相承，所以主体都是C系人，司马迁也被匈奴人忽悠了
http://onlinelibrary.wiley.com/doi/10.1002/ajpa.20429/abstract
In the present study, nuclear (autosomal and Y-chromosome short tandem
repeats) and mitochondrial (hypervariable region I) ancient DNA data
previously obtained from a 2,300-year-old Xiongnu population。。。
。。。 This result supports the hypothesis that the succession over time of
different Turkic and Mongolian tribes in the current territory of Mongolia
resulted in cultural rather than geneti... 阅读全帖 |
|
R*****d
发帖数: 1148 | 20 按照维基上的说法，目前埃及的木乃伊貌似还没有检测出结果，无论是Y还是线粒体：
http://en.wikipedia.org/wiki/List_of_DNA-tested_mummies
我去pubmed和google scholar上用Pharaoh，ancient Egyptian，mummy，Y haplogroup
mitochondria，等等排列组合搜了一下，貌似没有任何实质性的结果。
这里倒是有一篇英文论坛上的文章，两年前发表的，我依稀记得当时国内某论坛也跟风
讨论过。此文宣称图坦卡蒙等人的男性谱系是R1b，但却不是中东走廊-尼罗河下游相对
常见的R1b1a，而是当地较稀薄的R1b1b2。然而作者又说“not yet published
officially”，这就不得而知了。。。
Pharaoh Tutankhamun, Akhenaten and Amenhotep III were R1b
The Egyptians have tested autosomal and Y-DNA markers of three Pharaohs
of the 18th ... 阅读全帖 |
|
V****n
发帖数: 651 | 21 一个金发碧眼的YDNA为N的芬兰人，你会把他当作东亚人吗？
一个YDNA为O3,100%的中国人娶个100%白人女子，然后升个儿子，儿子继续娶个100%的
白人女子，持续10代，第十一代的男性后代直剩下1/1024的中国人基因，尽管他的YDNA
还是O3，你说他是中国人？
23andme基因测试，根据的是比较成千上万的SNP，每一个SNP都跟发生在Y染色体上YDNA
的单个SNP变异一样，不同的是绝大多数发生在autosome上。东亚人之间平均共同拥有
比如10000个SNP，跟尼人一样的有300个，那么东亚人携带3%尼人基因。欧洲和非洲人
群都拥有发生在23对染色体各个位置上的独特的成千上万个SNP变异。
每个人有30亿个碱基对，拷贝出错的频率在千万到亿分之一，也就是说每个人都有几十
个到几百个跟父母完全不同的碱基对变异。所以变异是常态，YDNA和MTDNA被研究的多
，无非是因为发生在性染色体上，是唯一可能被追踪研究的变异而已。而且所谓追踪，
对于一个男性指的是你可以查到300年前10代1024个祖宗里的一个而已，其它1023个除
非你有家谱否则根本无从知晓。亦是说你也一样继承另外... 阅读全帖 |
|
t******e
发帖数: 2504 | 22 人类有23对染色体，除了x/y那对性染色体外，其它22对，叫作常染色体，Autosomal
DNA(atDNA)， 现在对古人做分子人类学研究时，好的实验室都要尽可能的做atDNA。 |
|
n********g
发帖数: 6504 | 23 以下是发现于阿尔泰昆仑附近的西伯利亚的Ust'-Ishim人化石情况：
Neanderthal DNA in modern humans occurs in broken fragments; however, the
Neanderthal DNA in Ust'-Ishim man occurs in clusters, indicating that Ust'-
Ishim man lived in the immediate aftermath of the genetic interchange.[3]
The genomic sequencing of Ust'-Ishim man has led to refinement of the
estimated date of mating between the two hominin species to between 52,000
and 58,000 years ago.[3]
Ust'-Ishim人是智人和尼安德特人混血的后代。生活在混血后不远时期。尼安德特人基
因仍然连续。
Ust'-Ishim man is n... 阅读全帖 |
|
w******a
发帖数: 36 | 24 Yes, it is congenital and familial. Most common called idiopathic or essential
treor.
Cosidering this patientyoung age, and if there is no other causes (trauma,
alcoholic----more likely familial..
In more than half of the cases, essential tremor is inherited as an autosomal
dominant trait, which means that children of an affected individual will have
a 50% chance of also developing the disorder.
While the mainstays of treatment are drugs such as propranolol and primidone,
alternative drugs and s |
|
m********t
发帖数: 1 | 25 家有多囊肾病人,所以对这个比较关心,感觉最近几年多囊肾的研究进展很快,下面是昨
天(Nov.26)在自然上发表的文章.
对这个比较熟悉的请做一下评点.以及对整个多囊肾的治疗的预测.
Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor
roscovitine.
NO Bukanov, LA Smith, KW Klinger, SR Ledbetter, O Ibraghimov-Beskrovnaya
Polycystic kidney diseases (PKDs) are primarily characterized by the growth
of fluid-filled cysts in renal tubules leading to end-stage renal disease.
Mutations in the PKD1 or PKD2 genes lead to autosomal dominant PKD (ADPKD),
a slowly developing a |
|
f******I
发帖数: 769 | 26
it's autosomal recessive as far as genetic inheritance goes, but i think it'
s diagnosed by serum level though,
there are other reasons to have bronchiectasis that is non-infectious, from
cystic fibrosis to ciliary dysmotility to immune deficiency to RA, |
|
g***r
发帖数: 285 | 27
for autosomal dominant polycystic kidney disease, i don't think there is a
cure, most of them end up with end satge renal disease requiring
hemodialysis, you can consider kidney transplant, but you'd have higher risk
of complications comparing to other patients, |
|
n******s
发帖数: 210 | 28 I am not very familiar with this disease, but seems it is autosomal
recessive one.
So as long as your hubby is not carrier at same loci, your child would be OK
.
that's why marriage between blood relatives is prohibited. |
|
w***0
发帖数: 222 | 29 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 30 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 31 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 32 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 33 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 34 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 35 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 36 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 37 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 38 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 39 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
|
w***0
发帖数: 222 | 40 :))
遗传性的diseases, you will see those words, autosomal dominant, recessive, X
- chromsomal, mitochondrial etc. those are inheriable. However, other
diseases like Graves' Disease has genetic prodisposing factor, just like you
said, higher risk but not 遗传性的disease. |
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c**i
发帖数: 6973 | 41 I simply can not understand why Chinese parents from PRC whine.
Somehow I grt the feelings that Chinese parents often regret that they did
not abort their babies who have minor problems.
Can't they just say, "He Ain't Heavy, He's My Brother"?
http://en.wikipedia.org/wiki/He_Ain't_Heavy,_He's_My_
Can't they say I will accept my child no matter what, whether he or she is
gay or something else?
(1) 蒙古斑 Mongolian spot is very common among colored people including
Chinese. Perhaps you yourself, your ... 阅读全帖 |
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t**x
发帖数: 20965 | 42 wiki 上的：
Physical traits
47,XYY boys have an increased growth velocity from early childhood, with an
average final height approximately 7 cm (3") above expected final height.[4]
In Edinburgh, Scotland, eight 47,XYY boys born from 1967–1972 and
identified in a newborn screening program had an average height of 188.1 cm
(6'2") at age 18—their father's average height was 174.1 cm (5'8½"),
their mother's average height was 162.8 cm (5'4").[1][5] The increased gene
dosage of three X/Y chromosome... 阅读全帖 |
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u*****e
发帖数: 606 | 43 NS is an autosomal dominant disease which means if one of the parents carry
it, there is 50% of chance the baby will have the disease. So it is worth to
check the parents first to see if anyone of them carry this mutation. If
they do, then it is wise to give up having their own kid but go to adopt. A
NS kid is really a heavy burden/suffering to parents, family, the whole
society, and most importantly to him/herself. It's a really hard decision
for elder parents like LZ's friend to terminate preg... 阅读全帖 |
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I******e
发帖数: 6478 | 44 http://en.wikipedia.org/wiki/Spinal_muscular_atrophy
Spinal muscular atrophy affects individuals of all races, unlike other well
known autosomal recessive disorders like sickle cell disease and cystic
fibrosis which have significant differences in occurrence rate between races
. The overall incidence of SMA, of all types and across all ethnic groups,
is in the range of 1 per 10,000 individuals; the gene frequency is thus
around 1:100, therefore, approximately one in 50 persons are carriers.[8][9... 阅读全帖 |
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c*********8
发帖数: 125 | 45 Your classmate might have FSHD, facio scapulo humeral muscular dystrophy.
That is the third frequent muscular dystrophy. It is a autosomal dominant
genetic disease, so far there is no effective treatment.The life expectancy
could be normal, but need wheelchair life long.
The numbness in that disease sounds totally different from this case.
Xcontroller should be fine, he is only 33. Unless the situation is worsen
progressively, otherwise he does not need to see a doctor. |
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b*s
发帖数: 82482 | 46 来自主题: LeisureTime版 - 芝麻烧饼 However, a 2010 study[40] found variations in both production of odorous
urine and the ability to detect the odour, but that these were not tightly
related. It is believed most people produce the odorous compounds after
eating asparagus, but only about 22% of the population have the autosomal
genes required to smell them.[41][42][43]
In 2010, the company 23andMe published a genome-wide association study on
whether participants have "ever noticed a peculiar odor when you pee after
eating asparagu... 阅读全帖 |
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V****n
发帖数: 651 | 47 朋友认识一对清华老教授，四处为他们28岁左右的博士女儿找男朋友，不过一直找不到
合适的。
杰出的女性如果没有及时把优秀基因传递下去，实在是很浪费。由于X染色体携带众多
包括影响智力的隐形基因，杰出能力的女性一般都携带相当多双隐形基因，基本上相当
于出生时中了基因彩票（genetic lottery)，而同样能力的男性只需携带单个基因（所
以人数众多）。从传承角度讲，该类女性不论找什么样的老公，如果生儿子，基本上都
很可能同样杰出（当然autosomal的遗传也有影响）。而同样能力的男性则无此奢侈。
历史上杰出男性找了笨老婆几代就毁了基业的事情，实在是多得不能再多。
女性千百年来作为男性附属，基本上默默承担着传宗接代的义务。传统以来她们的价值
往往需要通过嫁个杰出的老公和生个杰出的儿子来表现。近百年来女性争取到了极大的
权利，不再是男人的附属。这当然是应当的，但不幸的是在传递基因这最根本的生物本
性方面，杰出女性却正好走向下坡路。剩女现象的出现，从一开始就跟女性权利和地位
的增加息息相关。从欧美到日本，到四小龙，现在到中国，莫不如此。根本的原因来自
女性本身生物性和社会性的冲突。如果读过... 阅读全帖 |
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t**i
发帖数: 688 | 48 重新整理一下：
Assuming all the facts were true;
Assume this phenotype is Mendelian and determined by an autosomal single
locus.
Assuming HWE.
Denote p = population allele frequency of Double-eyelids, q = 1 - p =
population allele frequency of single eyelid.
Then we have
Pr(Mother is hybrid) = 1;
Pr(GaoShuaiFu is pure recessive) = 1;
Pr(Father is hybrid) = 2pq, Pr(Father is pure Double-eyelid) = p*p
Then Pr(kid is Single-eyelid | Father is hybrid) = 1/4
Pr(kid is Single-eyelid | Father is pure Double)... 阅读全帖 |
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l*h
发帖数: 4124 | 49 45X with SRY translocation onto one of the autosomes, pretty rare.
？” |
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