p**********g
发帖数: 378 | 1 Approaches for the Development of Antiviral Compounds: The Case of Hepatitis
C Virus
Authors：Raymond F. Schinazi3, Steven J. Coats, Leda C. Bassit, Johan
Lennerstrand, James H. Nettles and Selwyn J. Hurwitz
丛书 Handbook of Experimental Pharmacology
图书 Antiviral Strategies
出版社 Springer Berlin Heidelberg
Year： 2009
Volume 189
页 25-51
ISSN 0171-2004
ISBN 978-3-540-79085-3 (Print) 978-3-540-79086-0 (Online)
Link：http://www.springerlink.com/content/g5w45q467m32u522/
十分感谢！！！ |
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p*******g
发帖数: 2976 | 2 【 以下文字转载自 Biology 讨论区 】
发信人: albertsmwk (.)(.), 信区: Biology
标 题: 第一批“青年千人计划”生物类@publication列表@
发信站: BBS 未名空间站 (Thu Aug 18 15:04:16 2011, 美东)
花了一个小时，深深的鄙视一下自己的无聊行径！！
125 蔡亮 男 1980年11月 复旦大学 生命
科学 2007年12月毕业于[美国]北卡大学 [美国]加州大学旧金山分校 博士后
Cai L, Mostov K. Polarity is destiny. Cell. 2009 Nov 13;139(4):660-2. PubMed
PMID: 19914162; PubMed Central PMCID: PMC2900917.
Cai L, Makhov AM, Schafer DA, Bear JE. Coronin 1B antagonizes cortactin and
remodels Arp2/3-containing actin branche... 阅读全帖 |
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A*******s
发帖数: 9638 | 3 Why so interesting? only 1% Bell's palsy presented with bilateral signs.
What does it tell you?
PCPs, ER Doc and some specialists are still using antiviral treatment for
bell's palsy. Studies showed it is not effective. What is effective?
Steroids if you start it early enough.
It makes sense in this case. Apparently his symptoms started after a unilateral HSV-1 infection. The HSV-1 infection associated autoimmune process explains why the infection was unilateral, but the bell's palsy was bilate... 阅读全帖 |
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i***l
发帖数: 9994 | 4 Avira Antivir or Kaspersky |
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k*******i
发帖数: 383 | 5 one comment:
Katherine36
5 Fans
23 hours ago ( 8:02 AM)
If it is not contagous, how is it spreading? I ask because I am sick with
one thing after another for the last couple years and have been tested for
everything known to doctors and came up negative. All doctors have done is
try to treat the basic symptoms as they do not know whats bringing these
illnesses on. I have been told my body creates too many antibodies that my
immune system works way to good. Antibiotics and antiviral medicines onl... 阅读全帖 |
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M******x
发帖数: 933 | 6 山寨就别说自主研发，或者说清楚到底哪部分是自主的，那部分是别人的。
放狗搜来的结果是
Peramivir is an experimental antiviral drug developed by BioCryst
Pharmaceuticals for the treatment of influenza. It has been authorized for
the emergency use of treatment of certain hospitalized patients with known
or suspected 2009 H1N1 influenza. |
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g***j
发帖数: 40861 | 7 【 以下文字转载自 WaterWorld 讨论区 】
发信人: deer2005 (老鹿), 信区: WaterWorld
标 题: 依博拉病（Ebola virus disease）：真相和热点
发信站: BBS 未名空间站 (Sat Oct 4 13:08:03 2014, 美东)
依博拉病（Ebola virus disease）：真相和热点
博客文章：
http://www.mitbbs.com/pc/pccon.php?id=14439&nid=338895
几天来，由于在德州Dalas发现美国国内首例病例，Ebola成了人们谈论的热点话题，
Ebola相关生化药股也在爆涨中。
Ebola可怕么？它如何传播？如何预防和治疗Ebola？
这里讨论了一些关于Ebola的热点问题：
（一）Ebola的真相
世界卫生组织（WHO）列举的关于Ebola的关键事实：
1. Ebola virus disease (EVD), formerly known as Ebola haemorrhagic
fever, is a severe, often fatal illness in ... 阅读全帖 |
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发帖数: 1 | 8 【Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH D005368
[edit on Wikidata]
Filariasis is a parasitic disease caused by an infection with roundworms of
the Filarioidea type.[1] These are spread by blood-feeding black flies and
mosquitoes. This disease belongs to the group of d... 阅读全帖 |
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发帖数: 1 | 9 12月28日 仔细阅读以下文章
或许这些文章可以告诉你们孩子被伤害病毒的答案。
Astellas Pharma 应该和这些人体实验有莫大的关系！
Founded 2005; 11 years ago
Headquarters 2-5-1, Nihonbashi-Honcho, Chūō-ku, Tokyo 103-8411, Japan
Key people Yoshihiko Katakana
(President and CEO)
Filariasis
From Wikipedia, the free encyclopedia
Filariasis
Life cycle of Wuchereria bancrofti, a parasite that causes filariasis
Classification and external resources
Specialty Infectious disease
ICD-10 B74
ICD-9-CM 125.0-125.9
Patient UK Filariasis
MeSH ... 阅读全帖 |
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w*********r
发帖数: 42116 | 10 去年得了流感，很不舒服，去看医生。医生说是流感，如果想确定，可以作测试79美元
。测试结果是流感。然后告诉我，如果愿意花钱，可以给我开一种缓解症状的药，保险
公司不COVER。我担心药是不是有问题，她给我查了，FDA approved antivirals，比
OTC药灵多了。
花生酱出问题那年，我经常拉肚子，医生查不出原因，就给我送营养师那里去了。 |
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m*****a
发帖数: 2160 | 11 你保险太差，基本的检查和治疗都不报，形同虚设
[在 withoutacar (我决定好好说话了。) 的大作中提到：]
:去年得了流感，很不舒服，去看医生。医生说是流感，如果想确定，可以作测试79美
元。测试结果是流感。然后告诉我，如果愿意花钱，可以给我开一种缓解症状的药，保
险公司不COVER。我担心药是不是有问题，她给我查了，FDA approved antivirals，比
:OTC药灵多了。
:花生酱出问题那年，我经常拉肚子，医生查不出原因，就给我送营养师那里去了。 |
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l**k
发帖数: 45267 | 12 100多的药当然是付得起的，但是大部分人都会嫌贵不买。
She declined the drug, even though her family could afford it.
"It's principle with her," her husband, Frank Holland, told the newspaper. "
She's a very frugal person in general, always has been."
Frank Holland went back to get the medicine, but three days later, on Feb. 4
, his 38-year-old wife died in the hospital from flu-related complications.
Most people with the flu won't even need oseltamivir or two other government
-approved antivirals, as those are recommende... 阅读全帖 |
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发帖数: 1 | 13 1. Hospitals nationwide discarded almost 2,700 kidneys between 2005-14,
according to a 2015 study published in the New England Journal of Medicine.
2, However, some hospitals no longer discard organs donated by patients with
hepatitis C. Thanks to antiviral medication, physicians can transplant the
infected organs into recipients. Infected organ recipients take medication
for eight to 12 weeks after the transplant to remove the virus from their
blood.
3, For one Arizona patient, accepting an inf... 阅读全帖 |
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c**********0
发帖数: 836 | 14 和国内合作现在是高危行业。
A researcher with ties to China was recently escorted out of the National
Microbiology Lab (NML) in Winnipeg amidst an RCMP investigation into what's
being described as a possible "policy breach."
Dr. Xiangguo Qiu, her husband Keding Cheng and an unknown number of her
students from China were removed from Canada's only level-4 lab on July 5,
CBC News has learned. The students didn't speak much English and kept to
themselves in a group.
A Level 4 virology facility is a lab equipped ... 阅读全帖 |
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w*********r
发帖数: 42116 | 15 友情提醒。用自己的ZIP CODE查查，看看哪个店里还有。 |
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v**e
发帖数: 8422 | 17 一般医用口罩就可以了， 不用一定要N95， 那东西带了很不舒服。
不去传染病医院也用不着。 |
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x****u
发帖数: 32 | 18 N95就够用了吧。真要到需要吸附病毒的时候，你也就进医院了 |
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x****u
发帖数: 32 | 19 我家就是买了一部分一般的n95和一部分level 3 surgical，然后囤了大量消毒喷雾和
alcoholic based sanitizer |
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w*********r
发帖数: 42116 | 20 注意卫生，不为了身体健康，防止被大陆老将嘲笑也是好的。 |
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C***S
发帖数: 1159 | 24 要点：罐装病毒导致的感冒占比是10%到30%。这次的不同之处是能攻击下呼吸道。R0在
2左右，感染能力一般。
这次宣传出了大问题，应该一开始就说新型流感，重症可以转化为肺炎。现在直接封城
，简单粗暴，是上了港灿和老酱的当。
Science News
How the new coronavirus stacks up against SARS and MERS
For the third time since around 2003, a coronavirus has jumped from animals
to people
2019-nCoV transmission electron micrograph
A new coronavirus called 2019 novel coronavirus, or 2019-nCoV, (seen here in
a transmission electron micrograph) is spreading in China. It is similar to
both SARS and MERS.
COURTESY: IVDC, C... 阅读全帖 |
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C*I
发帖数: 4736 | 25 有人说，和前些年送到国际病毒中心的菌株/原体是一样的。 如果一样， 问题不就很
简单和明白嘛？ 这因此就能解说通很多怪异的现象和反应了。
中国科学院武汉病毒国家研究所的P-4, P-3实验室：
2004年Sars之后建立的国家级national 病毒研究机构。下辖有P2，P3， P4 三个生物
病毒研究室。其中，P3 研究室是从事各种病毒的收集，保管，和对未完成培养的病毒
和材料的保存，管理，操作与使用。
P4 研究室：
It possesses complete level 4 biosafety protection facilities, management
and personnel system, and has the comprehensive abilities to conduct level 4
detection, isolation and identification, pathogenic characteristic analysis
, research on infection and pathogenic mechanisms, and the v... 阅读全帖 |
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V*****2
发帖数: 7930 | 26 Inhibition of SARS Coronavirus
Infection In Vitro with Clinically
Approved Antiviral Drugs
Emily L.C. Tan,* Eng Eong Ooi,† Chin-Yo Lin,* Hwee Cheng Tan,†
Ai Ee Ling,‡
Bing Lim,* and Lawrence W. Stanton*
自己GOOGLE一下，这文章超过1MB，黏贴不上来。 |
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i****d
发帖数: 724 | 27 这是微信里传的，有误导, 病毒并不比风尘颗粒要小
一般在公众场合防护飞沫，N95就可以了，antiviral的是給医护人员用的是防有毒液体
喷溅的，一般人用不着是overkill
吧： |
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w*********r
发帖数: 42116 | 28 疫情紧张，我很少去中国店、亚洲店，除了COSTCO，我就在公司解除几个大陆人。也不
知道这帮人买没买口罩。 |
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s******d
发帖数: 9806 | 29 口罩是东亚文明的象征。鬼佬不带口罩说明丫没有文化。 |
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i****d
发帖数: 724 | 33 凡是一般人能想到的店，比如walmart,target, homedepot, lowes, cvs, walgreen,
etc. 早就都抢光了 |
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f******t
发帖数: 19544 | 34 屯了一些冷冻食品，德国香肠、墨西哥对虾、比萨等等。 |
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w*********r
发帖数: 42116 | 38 antiviral口罩背后有个表格，能抵抗什么样的病毒，病毒编号最后数字看着像年份，
比如猪流感，A/SWINE/1976/31。就去查了一下，猪流感在美国两次outbreak，一次
Pandemic。outbreak发生在1976、1988，Pandemic在2009。具体多少人感染，死了多少
人倒是不重要。低级ID愿意的话，可以去努力去看看，都是英文，挺难。高级的就不用
关心了，因为有中级的会去把具体信息补充上。
美国应对不外乎是疫苗、药物和治疗，这三样大陆应该也有，大家根据自己的政治立场
，准备材料，在未来的几周内进行斗争。
药物、治疗方法。
绝大多数疾病都有治好的，都有没治好的。有没治好的，是不是就说明好了的是自愈而
不是治愈呢？本来我觉得没什么可讨论的，但我发现大陆人有不同的意见。台湾人、美
国人同意有个人的因素，但也承认治疗的效果，所以他们认为是治愈。
疫苗。
注射了疫苗，有没有副作用，甚至导致接种者死亡，死多少个算大面积死亡？美国死
500个的话，大陆死多少个才能让老将、小将满意？多少老将会有亲朋好友因为接种疫
苗死亡？会不会只有小将接种，老将根本就不接种。
注射了疫苗，... 阅读全帖 |
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w*********r
发帖数: 42116 | 39 这得看你在哪里了。Curad牌子的比较贵，CVS，Walgreens应还有卖。Target自己的品
牌up&up应该是没有了。
没在手边，不知道型号，上面会写着antiviral mask
有一个特殊的absorption layer在内层和外层中间，能吸附virus和mositure。 |
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w*********r
发帖数: 42116 | 40 我在宣布封城之前就告诉军版，美国antiviral的口罩已经短缺了。
老将要得就是在美国造大陆人把口罩买光的舆论。 |
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r**********1
发帖数: 221 | 41 https://www.zerohedge.com/health/man-behind-global-coronavirus-pandemic
His bio (source):
Peng Zhou, Ph.D., researcher, team leader of bat virus infection and
immunity. He successively obtained bachelor's and doctoral degrees from
Henan University (2004) and Wuhan Institute of Virology, Chinese Academy of
Sciences (2010). During his doctorate, he was sent to the Australian Animal
Health Laboratory for study. He then carried out research work at Duke-Nus
Medical College in Australia and Singapore... 阅读全帖 |
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t******r
发帖数: 8600 | 42 Newly developed direct-acting antiviral drugs can cure up to 95 percent of
patients. But the cure comes at a gigantic price. These drugs are
notoriously expensive. Gilead priced its first new hepatitis C drug,
sofosbuvir, at $1,000 per pill, or $84,000 for a three-month course of
treatment.
你个傻逼你一步三谎是吧？！
再说了，那药是cure，懂？ |
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y****z
发帖数: 27 | 43 Thai doctor says new drug combination treated coronavirus patient
From CNN’s Kocha Olarn in Bangkok
Doctors in Thailand say they have successfully treated one Wuhan coronavirus
patient with a combination of antiviral drugs, according to a briefing on
Sunday from the Ministry of Health.
Dr.Kriangsak Atipornwanich, a doctor at Rajavithi Hospital in Bangkok, said
he treated a 71-year-old female patient from China with a combination of
drugs used in HIV and flu treatments. He said the patient had pr... 阅读全帖 |
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l********e
发帖数: 52 | 44 请问哪种antiviral 可以当active control吗？ |
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发帖数: 1 | 45 速度还是可以的吧
April 15
First human infection with new influenza A H1N1 virus detected in California.
April 17
Second human infection with the new influenza A H1N1 virus detected in
California about 130 miles away from first infection, with no known
connection to previous patient.
April 18
First novel 2009 H1N1 flu infections were reported by CDC to the World
Health Organization (WHO) through the U.S. International Health Regulations
Program.
April 21
CDC publicly reported the first two U.S. infection... 阅读全帖 |
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发帖数: 1 | 46 CDC Communication Activities During the 2009 H1N1 Pandemic
The CDC response to the 2009 H1N1 pandemic was led by science and
continually evolved to meet the nation’s needs as events unfolded and as
more information became available. However, a consistent underlying
communications strategy underscored the entire CDC response. The strategy is
based on the emergency risk communications principles of quickly,
proactively and transparently communicating accurate information to the
public and to partn... 阅读全帖 |
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发帖数: 1 | 47 April 15
First human infection with new influenza A H1N1 virus detected in California.
April 17
Second human infection with the new influenza A H1N1 virus detected in
California about 130 miles away from first infection, with no known
connection to previous patient.
April 18
First novel 2009 H1N1 flu infections were reported by CDC to the World
Health Organization (WHO) through the U.S. International Health Regulations
Program.
April 21
CDC publicly reported the first two U.S. infections with th... 阅读全帖 |
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C***S
发帖数: 1159 | 49 Two patients suffering from severe coronavirus pneumonia and hospitalized in
the Cotugno hospital in Naples have been treated with Tocilizumab , a drug
that is usually used in the treatment of rheumatoid arthritis. The first
results are good. In China, Tocilizumab, a drug of choice in the treatment
of cytochemical release syndrome after treatment with CAR-T cells, is
already undergoing clinical trials in 14 hospitals in Wuhan.
The administration, which took place on Saturday and started for the ... 阅读全帖 |
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C***S
发帖数: 1159 | 50 跟我们老中医推荐的单抗比较起来怎么样？老中医一次治俩：
Two patients suffering from severe coronavirus pneumonia and hospitalized in
the Cotugno hospital in Naples have been treated with Tocilizumab , a drug
that is usually used in the treatment of rheumatoid arthritis. The first
results are good. In China, Tocilizumab, a drug of choice in the treatment
of cytochemical release syndrome after treatment with CAR-T cells, is
already undergoing clinical trials in 14 hospitals in Wuhan.
The administration, which took place on S... 阅读全帖 |
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