d*******t
发帖数: 273 | 1 拜谢！
关键词：Drug delivery, anticancer, nanoparticle, polymer, solubilization
email: [email protected]/* */ ,
或者站内联系。
多谢多谢！ |
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r***e
发帖数: 2539 | 2 Expert Rev Anticancer Ther. 2009 Apr;9(4):437-52.
r*********[email protected]
双黄包。 |
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y*****l
发帖数: 5997 | 4 T-DM1 Significantly Improved Progression-Free Survival in Randomized Phase
II Trial
3 hours 20 minutes ago - BIZ via Comtex
BusinessWireImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that
develops targeted antibody-based anticancer products, today announced that
Roche has disclosed positive top-line results from the first randomized
trial assessing trastuzumab emtansine (T-DM1, previously known as
trastuzumab-DM1) in HER2-positive metastatic breast cancer (MBC). T-DM1
consists of Immuno... 阅读全帖 |
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l****1
发帖数: 333 | 5 还有几篇，求帮助。
1.VEGF-C ShRNA inhibits pancreatic cancer growth and lymphangiogenesis in an
orthotopic fluorescent nude mouse model
Y Shi, M Tong, Y Wu, Z Yang, RM Hoffman, Y Zhang, Y Tian, M Qi, Y Lin, ...
Anticancer research 33 (2), 409-417
2.Intraoperative imaging of metastatic lymph nodes using a fluorophore-
conjugated antibody in a her2/neu-expressing orthotopic breast cancer mouse
model
J Wu, R Ma, H Cao, Z Wang, C Jing, Y Sun, Y Zhang, Z Yang, ...
Anticancer research 33 (2), 419-424 |
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发帖数: 1 | 6 楼主，我有兴趣，
Name： Jinsong TAO, Ph.D/Associate Professor
Email：[email protected]/* */
Research：Nanomaterials and nanotechnique application in anticancer
Affiliation/Institution：University of Maryland/South China University of
Technology
Professor Tao works for South China University of Technology (SCUT) in the
Top 1 major-ranked state key laboratory in China, Meanwhile, he is also a
visitor scholar of Materials Sci. and Eng. Dept. of University of Maryland
in USA.
His interests is as the follw... 阅读全帖 |
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l**********1
发帖数: 5204 | 7 ANTICANCER RESEARCH
IF pls refer:
//www.bioxbio.com/if/html/ANTICANCER-RES.html
original hint is from
//biosci.nju.edu.cn/professor.php?prof_id=153&page=2
more let her/him DIY
from link:
//www.medical-journals-links.com/oncology-cancer-biology.php |
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e*r
发帖数: 103 | 8 d*********[email protected]
如果有的话能发到这个邮箱吗？非常感谢！！！
Effect of some anti-inflammatory agents on lysosomal & testicular
hyaluronidases
Kushwah, A., Amma, M.K.P., Sareen, K.N.
Human milk composition: nutrients and bioactive factors.
Ballard O, Morrow AL.
2013
Recent Pat Anticancer Drug Discov. 2013 Jan 11. [Epub ahead of print]
HSP90 Inhibitors: Current Development and Potential in Cancer Therapy.
Sidera K, Patsavoudi E.
Adv Pharmacol. 2012;65:471-517. doi: 10.1016/B978-0-12-397927-8.00015-4.
HSP90 in... 阅读全帖 |
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C*********h
发帖数: 83 | 9 大致读了文章的摘要，应该是cell death领域的同行，做的方向主要还是apoptosis的
下游，呼吸链如何影响apoptosis的，以及cancer specific apoptosis以及ER-
mitochondria contact。
从Grimm的文章来看，他即便不是杰出的科学家，也是一个decent scientist。希望他
Rest in Peace.
如这篇review，citation 139.
The permeability transition pore in cell death.
Apoptosis. 2007 May;12(5):841-55. Review
这篇2011的EMBO J的citation是 81
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform
for apoptosis induction
Apoptosis重要的东西基本都做的差不多了，确实没什么可以做的。大lab都在做
physiology,做各种小鼠模型。Grimm凭一己之力做... 阅读全帖 |
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t***n
发帖数: 121 | 10 1. Curr Pharm Biotechnol. 2015;16(11):966-82.
Title : Process Development Strategies in Plant Molecular Farming.
http://www.ncbi.nlm.nih.gov/pubmed/26343135
3. Curr Protein Pept Sci. 2013 Nov;14(7):568-79.
Title : Heterologous production of peptides in plants: fusion proteins and
beyond.
http://www.ncbi.nlm.nih.gov/pubmed/23968345
4. Expert Opin Drug Deliv. 2015 Apr;12(4):653-67. doi: 10.1517/17425247.2015
.974546. Epub 2014 Oct 28.
Title: Elastin-like polypeptide for improved drug delivery for... 阅读全帖 |
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b*******g
发帖数: 1309 | 11 Carbohydrate-based vaccines are widely used to prevent infectious diseases,
but their use to fight cancer has so far proved problematic. To increase the
chance of success, researchers are pursuing a number of avenues that have a
common goal: enhance carbohydrates’ ability to induce the human immune
system to mount an effective fight against cancer.
Carbohydrates are studded all over the surfaces of human cells, where they
help with essential functions ranging from protein transport and cell-cell... 阅读全帖 |
|
发帖数: 1 | 12 ==
The risk of cancer is increasing significantly nowadays, which is a serious
social and health problem threatening human being. Hence, numerous
scientists continuously endeavor on this imperative issue for conquering the
malignant disease and declining the cancer incidence. Due to over 60% of
currently used anticancer agents are derived from natural sources directly
or indirectly, the discovery and development of new effective and safe
cancer inhibitors from folk medicines still is important r... 阅读全帖 |
|
发帖数: 1 | 13 ==
The risk of cancer is increasing significantly nowadays, which is a serious
social and health problem threatening human being. Hence, numerous
scientists continuously endeavor on this imperative issue for conquering the
malignant disease and declining the cancer incidence. Due to over 60% of
currently used anticancer agents are derived from natural sources directly
or indirectly, the discovery and development of new effective and safe
cancer inhibitors from folk medicines still is important r... 阅读全帖 |
|
yf
发帖数: 272 | 14 http://jop.ascopubs.org/content/early/2013/03/26/JOP.2012.00081
Perspective
Practicing Western Oncology in Shanghai, China: One
Group’s Experience
By David H. Garfield, MD, Harold Brenner, MD, FRCR (Lond), and Lucy Lu, RN
ProMed Cancer Centers–Shanghai, Shanghai, People’s Republic of China
In October 2011, we—David H. Garfield, MD, medical oncologist,
United States; Harold Jacob Brenner, MD, FRCR,
radiation oncologist, Israel; and Lucy Lu, oncology nurse,
Shanghai, China—were part of a group tha... 阅读全帖 |
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s********y
发帖数: 2 | 15 来自主题: Pharmaceutical版 - 关于研究方向 生物本科背景，申请PHD时,有个教授的研究方向如下，请问各位，这个方向对于今后在
制药行业发展有帮助吗？好找工作吗？谢谢啦～～～
(1) Discover novel anticancer compounds from Chinese herbal medicines using
a caspase sensor-based high throughput drug screening platform.
(2) Study the molecular mechanisms of anticancer agents in promoting cell
death using cell and animal models.
(3) Improve the efficacy and bioavailability of the drug candidates by
chemical modification and nanomization. |
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s********y
发帖数: 2 | 16 来自主题: Pharmaceutical版 - 关于研究方向 生物本科背景，申请PHD时,有个教授的研究方向如下，请问各位，这个方向对于今后在
制药行业发展有帮助吗？好找工作吗？谢谢啦～～～
(1) Discover novel anticancer compounds from Chinese herbal medicines using
a caspase sensor-based high throughput drug screening platform.
(2) Study the molecular mechanisms of anticancer agents in promoting cell
death using cell and animal models.
(3) Improve the efficacy and bioavailability of the drug candidates by
chemical modification and nanomization. |
|
发帖数: 1 | 17 ==
The risk of cancer is increasing significantly nowadays, which is a serious
social and health problem threatening human being. Hence, numerous
scientists continuously endeavor on this imperative issue for conquering the
malignant disease and declining the cancer incidence. Due to over 60% of
currently used anticancer agents are derived from natural sources directly
or indirectly, the discovery and development of new effective and safe
cancer inhibitors from folk medicines still is important r... 阅读全帖 |
|
发帖数: 1 | 18 ==
The risk of cancer is increasing significantly nowadays, which is a serious
social and health problem threatening human being. Hence, numerous
scientists continuously endeavor on this imperative issue for conquering the
malignant disease and declining the cancer incidence. Due to over 60% of
currently used anticancer agents are derived from natural sources directly
or indirectly, the discovery and development of new effective and safe
cancer inhibitors from folk medicines still is important r... 阅读全帖 |
|
y*****l
发帖数: 5997 | 19 来自主题: _pennystock版 - SPPI Spectrum Pharmaceuticals Announces ZEVALIN(R) and Belinostat Abstracts to Be
Presented at the American Society of Clinical Oncology Annual Meeting
4 hours 16 minutes ago - BIZ via Comtex
BusinessWireSpectrum Pharmaceuticals (NasdaqGS: SPPI), a biotechnology
company with fully integrated commercial and drug development operations
with a primary focus in oncology, today announced ZEVALIN(R) (ibritumomab
tiuxetan) and Belinostat abstracts will be presented at the 2011 Annual
Meeting of the American... 阅读全帖 |
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i***s
发帖数: 39120 | 20 英国卡迪夫大学医学院研究证实，中国抗肿瘤创新中药养正消积胶囊可有效抑制肿瘤细胞侵袭转移。
对于恶性肿瘤患者而言，最可怕的莫过于肿瘤出现转移扩散，因为这意味着肿瘤病变已经发展到晚期，也是肿瘤治疗失败的重要原因之一。今天在第七届中国肿瘤学术大会上披露，国际权威学术杂志《抗癌研究》（Anticancer Research）刊发了英国卡迪夫大学关于中药抑制肿瘤转移的研究报告，在国际上引起广泛关注。
英国卡迪夫大学医学院研究证实，我国抗肿瘤创新中药养正消积胶囊可有效抑制肿瘤细胞侵袭转移。研究人员指出，在肿瘤细胞的侵袭转移过程中，磷酸肌醇 3－激酶/蛋白激酶 B（PI3K/AKT） 信号通路的过度激活起到了关键作用，养正消积胶囊可以显著干预 PI3K/AKT 通路，从而对乳腺癌、肠癌、前列腺癌、肺癌、胃癌和骨肉瘤等肿瘤细胞的黏附和迁移起到明显抑制作用，有效控制肿瘤的病变发展。
有关专家介绍，恶性肿瘤细胞非常容易从原发病灶上脱落，每克肿瘤组织每天可向血液中释放 300―400万个肿瘤细胞，脱落的肿瘤细胞随血液或淋巴流布全身，一旦条件成熟就会迅速生长，形成转移性病灶。控制肿瘤细胞的侵袭扩散是避免肿瘤恶... 阅读全帖 |
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c****g
发帖数: 37081 | 21 175 small molecules anticancer drugs, 131, are not synthetic drugs, 85, are
natural products or derivatives. |
|
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l*******t
发帖数: 1016 | 23 美国疟疾爆发和癌症死亡率增高相关联
奇怪的是 CDC资料表明1950年到1994年 美国所有各州疟疾病一爆发 癌症病人死亡率
也越高。也就是说癌症病人 因为周围有其他人得了疟疾病就纷纷挂掉了，真是怪哉！
至今无法解释！ 但是得了疟疾的人 以后是不是就不得癌症 却没有资料。似乎一种解
释就是疟虫的蚊子叮咬癌症病人导致其死亡率增加。 Ref: Anticancer Research 2010
；30（4）：1371-1373。 |
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m******x
发帖数: 918 | 24 Email from [email protected]
/* */ to various associates
Sent: 21 October 2014
Dear all,
If anyone is interested how Professors are treated at Imperial College: Here
is my story.
On May 30th ’13 my boss, Prof Martin Wilkins, came into my office together
with his PA and ask me what grants I had. After I enumerated them I was told
that this was not enough and that I had to leave the College within one
year – “max” as he said.
He made it clear that he was acting on behalf of Prof Gavin Screaton, t... 阅读全帖 |
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s***j
发帖数: 52 | 25 推荐楼主一本书，可以解答你为什么得癌症以及如何防癌。
Anticancer: A New Way Of Life - David Servan-Schreiber
也有台湾译本。 |
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s*******i
发帖数: 12559 | 26 http://en.wikipedia.org/wiki/Basil
Health effects
Recently, there has been much research into the health benefits conferred by
the essential oils found in basil. Scientific studies have established that
compounds in basil oil have potent antioxidant, anticancer, antiviral, and
antimicrobial properties.[5][6][7][8] In addition, basil has been shown to
decrease the occurrence of platelet aggregation and experimental thrombus in
mice.[9] It is traditionally used for supplementary treatment of stres... 阅读全帖 |
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e***m
发帖数: 725 | 27 【 以下文字转载自 Chemistry 讨论区 】
发信人: eznwm (易美网络), 信区: Chemistry
标 题: job position: 波士顿北 小型药物公司 有机合成PhD needed
发信站: BBS 未名空间站 (Sat Feb 16 23:20:40 2013, 美东)
有兴趣可以把简历送给我，c*****[email protected]，背景合适我可以帮忙推荐。
公司支持H1B,满一年后支持办绿卡。
这个职位要招fresh PhD或者最多一两年经验。
各位好运。
Title: Scientist I, Oncology Drug Discovery
Responsibilities:
· Design and synthesize small molecule anticancer agents for
discovery programs
· Understand structure-activity-relationship (SAR) using parameters
specific to the project.
· ... 阅读全帖 |
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N*******3
发帖数: 625 | 28 Drinking Beer Might Save Your Brain Cells From Damage
Posted: 29/01/2015 13:26 IST Updated: 29/01/2015 13:26 IST
Love wine for its bouquet of health benefits? Try some beer too. According
to researchers, a beer compound can protect brain cells from damage.
It can also potentially slow the development of disorders such as Alzheimer'
s and Parkinson's diseases.
For this, Jianguo Fang from Lanzhou University's school of chemistry and
colleagues found that one compound found in hops called ... 阅读全帖 |
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d***n
发帖数: 12 | 29 这儿有一篇治疗肝癌的文章，因版权问题，不能贴全文．需要看全文的，请给我信箱留
言．
Anticancer Res 30(12):5145-5151 (2010)
Arabinoxylan Rice Bran (MGN-3) Enhances the Effects of Interventional
Therapies for the Treatment of Hepatocellular Carcinoma: A Three-year
Randomized Clinical Trial.
Background and Aims: This study examined the efficacy of arabinoxylan rice
bran (MGN-3) in conjunction with an interventional therapy (IT) for the
treatment of hepatocellular carcinoma patients. PATIENTS AND METHODS: A
total of sixty-eight patients wit... 阅读全帖 |
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h********n
发帖数: 4079 | 30 如果这个研究是可靠的, 不该只发在Anticancer Res这种档次的期刊上.
我不太相信.
II |
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g*****h
发帖数: 76 | 34 Thanks.
It is in the University. Anticancer drugs and mostly will do mice work. |
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d*****d
发帖数: 3081 | 35 A postdoctoral position is available to work on anticancer drug discovery in
the Department of Chemistry and Biochemistry at University of Wisconsin-
Milwaukee. The research will focus on synthesizing small molecules and
studying their biological properties (interactions with DNA, DNA damage,
cell damage). The lab has access to DNA synthesizer, HPLC, UV-Vis, gel
electrophoresis, Storm 860 and other equipments. NMR, Mass, and other big
equipments can be shared with the department and the campus. |
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m*********r
发帖数: 20 | 36 Technical [B.S.] and postdoctoral positions [Ph.D] are available for persons
interested to work in the area of anticancer drug pharmacology as it
pertains to brain tumors. You should have skills in at least one of the
following; analytical chemistry, cell biology, molecular pharmacology, tumor
models, animal surgery, microdialysis or pharmacokinetics. Send electronic
resume or CV to James M. Gallo at j*********[email protected]
I am posting for my advisor. Best lab I've joined so far... |
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o*********n
发帖数: 14 | 37 Hi there,
I will launch a startup company in May in Wuhan, pursuing anticancer drug R&
D. I am looking for several team members. If interested, you may call me (
414-6282391) for a discussion.
Eric Cheng |
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b**********9
发帖数: 87 | 38 http://www.bio.whu.edu.cn/News_reads.asp?cid=174&id=3053
周 宇
职称职务：研究员
学科专业：生物信息与功能基因组学
研究方向：生物信息学、功能基因组学、RNA组学
实验室位置：生命科学学院6109、6101室
联系电话：027-68756749
Email: [email protected]
/* */
学习经历
1999-09－2003-06 武汉大学 本科 生物学基地班
2003-09－2004-09 武汉大学 硕士 生化与分子生物学
2004-10－2005-07 法国巴黎十一大学 硕士 生物信息与生物统计学
2005-09－2008-12 武汉大学 博士 生化与分子生物学
2005-09－2008-12 法国巴黎十一大学 博士 计算机 (与武汉大学联合培养）
主要工作经历及任职情况
2009-07－2015-05 美国加州大学圣地亚哥分校 博士后
2015-05－至今 武汉大学 研究员
2015-08－至今 武汉大学高等研究院 兼职研究员
主要研究领域及兴趣
近年来发展起来... 阅读全帖 |
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d*******u
发帖数: 5337 | 39 Hi reviewers,
I wish you all have a happy new year.
Please check the following manuscripts to Biomedicine and pharmacotherapy.
If you are interested in reviewing these manuscripts, send your background
and Ms #. Feel free to pass this information to your friends and collogues.
Best regards,
xxxx
Executive editor
Biomedicine and Pharmacotherapy
1. Antiproliferative activity of Corylus avellana L. extracts against
human cancer cell lines
2. Poloxamer Surface modified Trimethyl Chitosan Nano... 阅读全帖 |
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l*****n
发帖数: 204 | 40 Many thanks to: jn74612001 (TCO), lightgreen (四月芽), freefreefree (
ChemIsTry), dianzi2004 (electron), bigbigdeal (bigbigdeal), eveliyi (Eve),
for their help.
Background (cancer research and discovery & development of anticancer drug):
chemistry-->medicinal chemistry-->biochemistry, pharmacology, cell biology.
Publications:
One Nth author science
Conference poster: 6 (3 1st author)
One oral conference presentation
All other papers are in Chinese:
1st author: 4
2nd author: 4
Nth author: 6
One Nth |
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s**********u
发帖数: 1 | 41 looking for review opportunities in the field of Natural Product Chemistry
Discovery of anticancer drug from microorganisms. |
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t****a
发帖数: 439 | 42 Keywords： peptidoglycan extracts
anticancer activity in vitro
Please response only if you are qualified for the topic, with a brief self
introduction and contact information.
Thanks. |
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n******i
发帖数: 374 | 43 您好，希望能把这次机会给我，谢谢了
Yarong Liu
2623 Ellendale Pl.
Los Angeles, CA 90007
(213) 249-2419
y*******[email protected]
www.linkedin.com/pub/yarong-liu/2b/a36/65b/
PUBLICATIONS
1. Yarong Liu, April Tai, Kye-Il Joo and Pin Wang. “Visualization of DC-
SIGN-mediated entry pathway of engineered lentiviral vectors in target cells
” 2013, PLoS One 8(6): e67400.
2. Liang Xiao, Kye-Il Joo, Yarong Liu, Jinxu Fang and Pin Wang. “
Injectable thermo-sensitive hydrogel as an adjuvant: in vivo modulation of
dendritic ... 阅读全帖 |
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w****i
发帖数: 233 | 44 Area: Toxicology; anticancer agents assay; biochemistry.
Note: this manuscript is NOT a typical analytical method or PK paper such as
LC, LC/MS, GC method. It is more related to biochem.
Send me your name, email and brief CV. Thanks. |
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i********n
发帖数: 171 | 45 1.Anti-diabetic and anti-obesitic effects of aqueous extracts of
Yangkyuksanhwa-tang and its two major compositions on db/db mice
2.13-Methyltetradecanoic acid induces bladder cancer cell autophagy via ROS-
mediated PI3K/AKT and MAPK pathways
3.Ticagrelor inhibits oxLDL-induced migration of dendritic cells via miR-145
-5p mediated HSPA14 downregulation resulting in repressed atherogenesis
4.Co-delivery of IL17RB siRNA and doxorubicin by chitosan-based
nanoparticles for enhanced anticancer effica... 阅读全帖 |
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i********n
发帖数: 171 | 46 请发邮件到[email protected]/* */
1. Synthesis and characterization of chitosan–polyvinylpyrrolidone–
bovin serum albumin coated magnetic iron oxide nanoparticles as potential
carrier for delivery of tamoxifen
2. n-vitro and In-silico anticancer potentials of taxoids isolated from
Taxus wallichiana Zucc
3. Homology modeling and virtual screening for inhibitors of lipid kinase
PI(4)K from Plasmodium
4. Evidence for the involvement of nitric oxide in cholestasis-induced
itch associated... 阅读全帖 |
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d*******t
发帖数: 273 | 47 顶，律师建议再多凑几个review，多谢大家帮忙了！ |
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i********n
发帖数: 171 | 48 发你的简历和相应的一下文章编号到： [email protected]/* */, 如果方便也请在这里回复你
想要审稿的编号这次有五篇审稿。
请大家忽略我之前的文章，如果需要审稿，经常关注我在本版的文章，谢谢，不定期有
生物医学的审稿
1. The extracellular region of the HER2 protein affects breast cancer
cells
2. Ghrelin Protects against Palmitic Acid or Lipopolysaccharide-Induced
Hepatocyte Apoptosis through Inhibition of MAPKs/ iNOS and Restoration of
Akt/eNOS Pathways
3. Improvement of ursolic and oleanolic acids’ antitumor activity by
complexation with hydrophilic cyclodextrins
4. Cytopr... 阅读全帖 |
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i********n
发帖数: 171 | 49 有审稿意愿的请发送你的CV到[email protected]/* */并告知你希望审稿的文章编号
请有时间愿意多审几篇的也可以，只要你能保证质量，之前有些审稿人有些敷衍，希望
大家能认真对待。谢谢合作。
1. Comparative assessment of cytotoxic effect of Cuban and Brazilian
propolis in human laryngeal epidermoid carcinoma cells
2. Role of PI3K/AKT/mTOR signaling pathway in ostearthritis by regulating
articular chondrocytes autophagy in rats
3. CREB knockdown inhibits growth and induces apoptosis in human pre-B
acute lymphoblastic leukemia cells through inhibition of prosurvival sig... 阅读全帖 |
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G****a
发帖数: 10208 | 50 Although Amgen is the world’s biggest biotechnology company, the drug maker
has been mostly absent from one of the industry’s biggest and fastest-
growing markets: cancer drugs.
It took a big step to fix that on Sunday, agreeing to buy Onyx
Pharmaceuticals for about $10.4 billion in cash to gain access to the
company’s three anticancer treatments.
Under the terms of Sunday’s deal, Amgen will offer $125 a share in cash
through a tender offer for Onyx’s shares. The transaction is expected to
close... 阅读全帖 |
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