l*****g
发帖数: 2087 | 1 中国科学院院士李家洋
生平简介
李家洋（1956.7-）安徽肥西人。植物分子遗传学家，中国科学院院士，研究员。
中国
科学院副院长、党组成员。1982年毕业于安徽农学院（现安徽农业大学），1991年获美国
布兰代斯（Brandeis）大学博士学位，1991—1994年在美国康乃尔大学汤普逊（Boyce
Th
ompson）植物研究所进行博士后研究工作。历任中国科学院遗传研究所所长助理、所长，
遗传与发育生物学研究所所长。
李家洋主要从事植物分子遗传学研究，他利用模式植物拟南芥与重要粮食作物水稻探
索植物生长发育的调控机理。近年来的主要研究工作包括：采用图位法克隆了水稻分蘖控
制基因MOC1，开拓了水稻分蘖控制分子机理研究的新领域；利用水稻脆秆突变体分离了
B
C1基因，阐述了水稻机械强度的控制机理；通过获得的拟南芥胆碱生物合成突变体，初步
明确了胆碱合成与植物温度敏感雄性不育性的关系；通过图位克隆法分离出导致细胞死亡
的基因MOD1，明确了初级代谢途径的缺陷会导致植物细胞凋亡；利用转基因技术，创制出
色氨酸与吲哚乙酸合成量改变的转基因植物，从而提出植物生长素吲哚乙酸生物合成途径
的新模... 阅读全帖 |
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B****2
发帖数: 8892 | 2 我开始还以为与波士顿马拉松有关，故意采取的预防措施。
以后回国归来时，最好别带高压锅。
http://www.usatoday.com/story/travel/flights/2013/05/13/saudi-p
DETROIT — Federal agents arrested a suspicious traveler with an altered
Saudi Arabian passport at Detroit Metro Airport over the weekend after
discovering a pressure cooker in his luggage.
According to a criminal complaint filed Monday in U.S. District Court, the
passenger, Hussain Al Khawahir arrived Friday at the Detroit airport from
Saudi Arabia via Amersterdam. He had a visa and a Saud... 阅读全帖 |
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s*******w
发帖数: 2257 | 3 回应正在生气的孩子的正确方法(中英双语)
来源: karlshen 于 2015-09-04 16:09:27 [档案] [博客] [旧帖] [给我悄悄话] 本文
已被阅读：16482 次 (35241 bytes)
字体：调大/重置/调小 | 加入书签 | 打印 | 所有跟帖 | 加跟贴 | 当前最热讨论主题
When children get upset, the cannot be reached by reasoning. When angry,
they respond only to emotional balm.
当孩子烦躁不安时，讲道理是没有用的。他们生气时，只有情感上的安慰，他们才听得
进去。
Dr. Haim G. Ginott
文/海姆·G·吉诺特
Two young siblings, were playing in the basement. Suddenly a noise of
destruction, followed by shouting and accusations, was heard. Red with anger
, Billy, age ... 阅读全帖 |
|
as
发帖数: 5 | 4
In postgresql user's guide, I found:
ALTER TABLE name1 ADD COLUMN name2 type
or
ALTER TABLE name1 RENAME TO name2 |
|
y**i
发帖数: 18 | 5 I've problems with Oracle Lite SQL*Plus.(WINNT)
SQL> ALTER USER SYSTEM IDENTIFIED BY SYSTEM;
ALTER USER SYSTEM IDENTIFIED BY SYSTEM
*
ERROR at line 1:
OCA-30021: error preparing/executing SQL statement
[POL-5228] syntax error
SQL> CREATE USER TEST IDENTIFIED BY TEST;
CREATE USER TEST IDENTIFIED BY TEST
*
ERROR at line 1:
OCA-30021: error preparing/executing SQL statement
[POL-5228] syntax error
SQL> password
Changing password for SYSTEM
Old password: ******
Operating System error occurred
Passwo |
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a**m
发帖数: 17 | 6 What's in alert log?
Try to start manually;
svrmgrl
connect internal
startup no mount
alter database mount
alter database open
Then see when it hung and fix related problems |
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l***r
发帖数: 459 | 7 Got two simple questions on oracle backup and archive:
1) I try to use backup wizard but it requires oracle management server connection
However, when I try to connect oracle management server, it tells me wrong
host name or status of oracle management server.
I wonder what I should do? I am using OEM.
2) I found I only have spfile for my oracle instance and no init.ora. I use
startup mount, alter database archive and alter database open to change to
archive mode. However, it only archives when |
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l***r
发帖数: 459 | 8
select table_name from user_tables;
alter table drop column ;
alter table add ; |
|
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b****r
发帖数: 113 | 9 mysql version 4.0.20a, on winxp. Innodb type table.
I use "alter table tbl_name drop col_name" to drop a column,
but it failed twice.
From the dos window on XP, the comman "alter table" hang on there for ever.
After reboot the machine, the column is still there,
and data in this column are still fine.
The table has about 20 million rolls. Is the size a prolbem?
Thanks for any help. |
|
B*********L
发帖数: 700 | 10 解决了。
1. Move tempdb files to new location(ramdisk).
USE master;
GO
ALTER DATABASE tempdb
MODIFY FILE (NAME = tempdev, FILENAME = '{new location}\tempdb.mdf');
GO
ALTER DATABASE tempdb
MODIFY FILE (NAME = templog, FILENAME = '{new location}\templog.ldf');
GO
2. after reboot machine, new tempdb files are re-created to the ramdisk. |
|
g***l
发帖数: 18555 | 11 我找到了一个SCRIPT LOGIN的
USE master
GO
IF OBJECT_ID ('sp_hexadecimal') IS NOT NULL
DROP PROCEDURE sp_hexadecimal
GO
CREATE PROCEDURE sp_hexadecimal
@binvalue varbinary(256),
@hexvalue varchar (514) OUTPUT
AS
DECLARE @charvalue varchar (514)
DECLARE @i int
DECLARE @length int
DECLARE @hexstring char(16)
SELECT @charvalue = '0x'
SELECT @i = 1
SELECT @length = DATALENGTH (@binvalue)
SELECT @hexstring = '0123456789ABCDEF'
WHILE (@i <= @length)
BEGIN
DECLARE @tempint int
DECLARE @firstint in... 阅读全帖 |
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g***l
发帖数: 18555 | 12 那不就是个TABLE UPDATE的问题么？TABLE里没有RANK COLUMN给你吧，你如果还要去
ALTER TABLE的话，那你这个SP就很外行了，原则是不让你改TABLE，你弄个TEMP TABLE
，RANK完一个放进去，TABLENAME也做成个COLUMN,然后RANK第二个再放进去，最后一次
性显示出来。如果你去ALTER TABLE的话，RUN两次在同一个TABLE加同样的COLUMN当然
会出错，这种做法也很不专业。 |
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j***a
发帖数: 10844 | 13 alter database close;
alter database dismount; |
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l******y
发帖数: 60 | 14 都是高手！cume_dist()我从来没用过 :-(
tt原来在的tablespace是啥——不会看呀
确认已打开了flashback——正解，确实没打开，但怎么打不开呢？我从dba账户也打不
开，为什么呢？
SQL> select log_mode, flashback_on from v$database;
LOG_MODE FLASHBACK_ON
------------------------ ------------------------------------
NOARCHIVELOG NO
SQL> alter database flashback on;
alter database flashback on
*
ERROR at line 1:
ORA-00439: feature not enabled: Flashback Database |
|
h****p
发帖数: 25 | 15 如果需要使用flashback database ，则用以下命令
1. set parameter db_recovery_file_dest and db_recovery_file_dest_size
2. restart db to mount status
3. alter database archivelog & alter database flashback on
4. open database
如果只是测试flashback drop，则无须归档模式，以及flashback on
仅 enable recyclebin即可
只是recyclebin不支持system表空间对象，即如果你的tt表是sys或者system用户默认
创建的，是不能恢复的。用 show recyclebin命令查看已删除对象 |
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s**m
发帖数: 1564 | 16 This is about extended property.
Here is background: when a table/column is created/altered/dropped, extended
properties are inserted/updated/deleted. also table's/column's extended
property can be updated later (not via alter table/column syntax) using
below system procedures (or raw insert/update/delete scripts):
sp_addextendedproperty
sp_updateextendedproperty
sp_dropextendedproperty
Here is my goal: now when an extended property is created/updated/dropped, I
want to fire a trigge... 阅读全帖 |
|
s*******n
发帖数: 4402 | 17 Column不确定是可以的，有两种办法：
1. 如果非要用SQL一步做到就这样：
比如你的数据一共是n行, 新建一个table: #Table
declare @n int set @n=n, @count int
declare @upd varchar(1000)
set @count=1 开始循环
while(@count<=@n)
begin
set @upd='Alter Table #Table Add Column+convert(varchar(10), '+@count+')
datetime'
exec(@upd) --这个Alter table 好像只能这样自动执行。
set @count=@count + 1
end
这样出现的column 就是 column01, column02, ...
然后再用同样的办法把数据update进去。
2. 或者你可以把行变成列倒过来，在SQL里生成，再换到Excel里面再倒过来。
反正只要能弄出最后的效果就可以。 |
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E******n
发帖数: 641 | 18 ☆─────────────────────────────────────☆
veggie (走位飘忽) 于 (Fri Jul 24 12:48:28 2009, 美东) 提到:
Microsoft alters Laptop Hunters "Lauren" ad after Apple calls to complain
by Laura June, posted Jul 24th 2009 at 12:31PM
In a continuation of the saga that began about ten days ago, Microsoft has
altered one of its Laptop Hunters ads to reflect Apple's recent price
changes. Last we'd heard, Microsoft COO Kevin Turner was boasting that the
ads had been so successful that a rep from Apple had called to |
|
e***y
发帖数: 4472 | 19 Google Chrome Terms of Service
These Terms of Service apply to the executable code version of Google Chrome
. Source code for Google Chrome is available free of charge under open
source software license agreements at http://code.google.com/chromium/terms.html.
1. Your relationship with Google
1.1 Your use of Google’s products, software, services and web sites (
referred to collectively as the “Services” in this document and excluding
any services provided to you by Google under a separate writte... 阅读全帖 |
|
g*****g
发帖数: 34805 | 20 给微软抹粉真是嘛都敢说。
http://www.javaworld.com/javaworld/jw-10-1997/jw-10-lawsuit.htm
Specifically, Microsoft made the choice last week to ship products it claims
are fully Java 1.1 compliant, but which failed to pass the Java 1.1
compatibility tests the company received from Sun in February.
Specifically, Microsoft does not support the Java Native Interfaces (JNI)
or the Remote Method Invocation (RMI), and it has altered the Core Java
class libraries with about 50 methods and 50 fields that are not part... 阅读全帖 |
|
t**r
发帖数: 3428 | 21 (def the-world (ref "hello"))
(def bizarro-world (ref {}))
"Two worlds are better than one"
(= ["Real Jerry" "Bizarro Jerry"]
(do
(dosync
(ref-set the-world {})
(alter the-world assoc :jerry "Real Jerry")
(alter bizarro-world assoc :jerry "Bizarro Jerry")
(vec (map #(:jerry @%) [the-world bizarro-world]))))))
看最后一行。逻辑不难 但是符号太多。 |
|
发帖数: 1 | 22 給臺灣讀者：國立彰化師範大學教授胡瀚平長期抄襲剽竊
劉 正
臺灣教育部領導 暨
國立彰化師範大學校長郭豔光教授（[email protected]/* */）
副校長李清和教授（[email protected]/* */）
副校長陳明飛教授（[email protected]/* */）
國文學系系主任、臺灣文學研究所所長王年雙教授（[email protected]/* */）
您好！
本人是大陸前 武漢大學、中國人民大學、華東師範大學教授、日本國大阪市立大學文
學博士、日本國京都大學博士後研究員。現旅居美國，為美國漢納國際作家協會副會長。
今日在網路上和刊物上驚訝地發現貴大學國文學系暨臺灣文學研究所教授胡瀚平長期抄
襲我的論著，貴所胡瀚平的《易學在西方》一文不加任何說明地全文百分之七十以上全
文抄襲剽竊我的論著。在此，我將貴所胡瀚平的《易學在西方》一文（《國文學志》第
二卷，頁89-103，1998年6月。）全文附上，並附上我的《中國易學預測學》（1991年
，大陸紅旗出版社初版）中的中篇第四章《西方易學史》的145-160頁部... 阅读全帖 |
|
s**u
发帖数: 9035 | 23 Neurological Diseases and Receptor Pharmacology--Post-doctoral position at the NIA
Department of Health and Human Services
National Institutes of Health
National Institute on Aging
The National Institute on Aging (NIA), a major research component of
the National Institutes of Health (NIH) and the Department of Health
and Human Services (DHHS), is recruiting for a postdoctoral research
position in the Receptor Pharmacology Unit of the Laboratory of
N... 阅读全帖 |
|
s******a
发帖数: 472 | 24 http://www.cell.com/molecular-cell/fulltext/S1097-2765(11)00331
Fifty Years after Jacob and Monod: What Are the Unanswered Questions in Molecular Biology?
=====================================================================
Tomorrow's Molecular Biology
Marc W. Kirschner
Harvard University
Today, the term molecular biology has a rather prosaic sound. After all,
there is little in contemporary biology that isn't molecular. It's hard to
remember that 50 years ago, molecular biology was distinctly ... 阅读全帖 |
|
g********0
发帖数: 6201 | 25 Federal Grant Bar for Neurologist
02/29/2012 David Pittman
A former SUNY neurology department chair has been found guilty of
fabricating data in two published papers, four grants applications, and a
submitted manuscript.
A former State University of New York (SUNY) neurobiology department chair
has been banned from conducting federally funded research for a year and
will have his work supervised for another two years. The ban is the result
of an investigation that found he falsified data in two ... 阅读全帖 |
|
f******g
发帖数: 1003 | 26 IDH1(R132H) mutation increases murine haematopoietic progenitors and alters
epigenetics.
Nature, 2012
These alterations are gain-of-function mutations in that they drive the
synthesis of the 'oncometabolite' R-2-hydroxyglutarate (2HG).
These mutants show increased numbers of early haematopoietic rogenitors and
develop splenomegaly and anaemia with extramedullary haematopoiesis.
表型不是特别明显。
是不是可以人为IDH1的突变只是helper mutation呢? |
|
p*****c
发帖数: 20445 | 27 A-D E-K L-P R-Z
Peter Baumann, Ph.D.
HHMI Early Career Scientist
Stowers Institute for Medical Research
Peter Baumann’s research focuses on beginnings and endings: beginnings in
the form of reproduction in unisexual lizards and endings in the form of the
telomeres that protect chromosome tips.
Each time chromosomes are copied, telomeres—specialized stretches of DNA
that extend from the ends of each chromosome—become progressively shorter.
With each cell division, they ero... 阅读全帖 |
|
c********n
发帖数: 67 | 28 The alterations of glycosylation in malignant diseases.
PMID: 23488288
Glycosylation changes on serum glycoproteins in ovarian cancer may
contribute to disease pathogenesis
PMID: 19126966
Alterations in glycosylation as biomarkers for cancer detection
PMID: 20354203
h***[email protected]
Thanks very much for you kindly help. |
|
k****s
发帖数: 1209 | 29 原文在
http://www.skizit.biz/2013/07/21/ecdysone-insect-hormone-an-ind
Ecdysone Insect Hormone Switches on Disease
21 Jul 2013 | ECDYSONE
MORGELLONS:
INSECT HORMONE ECDYSONE TRIGGERS GENETIC CHANGES
TO BUILD NEW HAIR, SKIN, NAILS and CAUSE DISEASES
SkizitGesture-2013
Morgellons is a military grade entomological terror weapon being used to
torture and kill innocent civilians. The medical community has not been
informed about this disease and its complexity keeps it from being properly
identified, ... 阅读全帖 |
|
h********8
发帖数: 49 | 30 索性把我最近看的文献的摘要发出来。有谁看到有趣的做癌症诊断的公司，麻烦告诉我
一声哈。谢谢！
约翰斯•霍普金斯大学Kimmel癌症中心
（文献1， 2012年11月） 不依赖于已知癌症基因组成而检查肿瘤DNA的方法。研究人员
从取自10位结肠癌和乳腺癌患者的血液标本里分离出DNA。然后，他们使用下一代DNA测
序技术读取了血液DNA中的全部基因组。结果显示，癌症患者的血液DNA都出现了染色体
拷贝变化和重排，而10个健康对照组成员的DNA没有异常。
癌症患者血液中来自肿瘤的DNA所占比例从1.4%到47.9%，差异很大。这种新检测法还可
能需要从肿瘤DNA低于0.1%的血液样本中检查出小的、可治愈的肿瘤。只需要做更多的
测序就能克服这些困难。这项实验有望在未来5到10年内用于临床
（文献2，2013年1月）利用常规巴氏检测（Pap test）获得的宫颈分泌物来检测卵巢癌
及子宫内膜癌。在一项初步研究中，研究人员采用这种命名为“PapGene”的测试方法
，依靠全基因组测序癌症特异性突变，检测出了全部24个子宫内膜癌，以及22个卵巢癌
其中的9个，准确率分别为100%和41%... 阅读全帖 |
|
m******g
发帖数: 467 | 31 Nature 14.04.17
稍微了解一下：
1. miRNAs trigger widespread epigenetically activated siRNAs from
transposons in Arabidopsis
easiRNA resemble secondary siRNA
latent mechanism that targets tranposon transcripts
小知识：
1. Sperm RNA carries marks of trauma
Stress alters miRNA expression level in mice
which leads to depressive behavior in later generations
stress on mother, F2 generation of F1 males shows disorder
so does F3
2. Dissecting appetite
The hunger circuits has been mapped in mouse
3. Mouse already... 阅读全帖 |
|
O******e
发帖数: 4845 | 32 我推荐大家都读一下这篇文章：
http://www.pnas.org/content/111/16/5773.full
全文：
By Bruce Alberts, Marc W. Kirschner, Shirley Tilghman, and Harold Varmus
By many measures, the biological and medical sciences are in a golden age.
That fact, which we celebrate, makes it all the more difficult to
acknowledge that the current system contains systemic flaws that are
threatening its future. A central flaw is the long-held assumption that the
enterprise will constantly expand. As a result, there is now a severe
imbalan... 阅读全帖 |
|
s********3
发帖数: 231 | 33 《科学》对STAP手稿的专家评审意见曝光
《科学》对传说中的STAP细胞论文的三名评审专家意见，过去一直被雪藏，今天终于
被曝光。专家对这一研究的评价不高，认为非常全面的描述性研究，如果结果确定，可
能导致发育生物学大厦的颠覆，其实是不相信这种研究结论。因为没有当时的投稿件，
所以没有办法对这些评价进行更深入分析。不过这些资料显然都在某个地方，只是拥有
的人不愿意拿出来。
Retraction Watch readers are of course familiarwith the STAP stem cell saga,
which was punctuated by tragedy last month whenone of the authors of the
two now-retracted papers in Nature committed suicide.
In June, Science‘s news section reported:
Sources in the scientific community confirm that early version... 阅读全帖 |
|
s********6
发帖数: 89 | 34 http://www.amc.edu/PR/PressRelease/04_20_15_drs.html
http://www
Albany Med Announces 2015 Recipients of Albany Prize in Medicine
Albany, N.Y., April 20, 2015—A pair of scientist/inventors who developed
widely used modern research technologies that promise to accelerate medical
discoveries have been announced as the recipients of the Albany Medical
Center Prize in Biomedicine and Biomedical Research for 2015. They are:
Karl Deisseroth, M.D., Ph.D., D.H. Chen Professor, Professor of
Bioengineering... 阅读全帖 |
|
t**m
发帖数: 158 | 35 看一作小姑娘讲的，的确真够拼的啊！
发信人: feimeng (梧桐树，三更雨，不知多少春秋), 信区: TsinghuaCent
标 题: 对话施一公及其团队：世界级难题是如何破解的
发信站: 水木社区 (Mon Aug 24 13:15:21 2015), 站内
8月21日凌晨，一位德国同行的电话，打乱了清华大学生命科学学院院长施一公的工作计
划。这位德国同行，刚刚看到了《科学》在线发表的施一公团队撰写的两篇关于剪接体
结构及其工作机理的研究长文。
这几天，有关施一公的“新闻”不断。6天前的8月18日，他的研究团队刚刚在《自然》
在线发表了一篇研究长文，首次揭示了分辨率高达3.4埃的人体γ-分泌酶的电镜结构，
为理解阿尔茨海默症的发病机理提供了重要基础。翌日，他拟任清华大学副校长的任命
，进入公示期。
然而，这一次，施一公说，这两篇论文带给他的兴奋，超出了过去25年科研生涯的总和
。
21日中午，记者第一时间赶到清华大学，与施一公和他的3名85后团队成员展开了一场对
话。
“不可能完成的任务”
记者：剪接体结构解析被公认是结构生物学领域的终极难题，你们是如何完成这看似“
不可能完... 阅读全帖 |
|
t**m
发帖数: 158 | 36 看一作小姑娘讲的，的确真够拼的啊！
发信人: feimeng (梧桐树，三更雨，不知多少春秋), 信区: TsinghuaCent
标 题: 对话施一公及其团队：世界级难题是如何破解的
发信站: 水木社区 (Mon Aug 24 13:15:21 2015), 站内
8月21日凌晨，一位德国同行的电话，打乱了清华大学生命科学学院院长施一公的工作计
划。这位德国同行，刚刚看到了《科学》在线发表的施一公团队撰写的两篇关于剪接体
结构及其工作机理的研究长文。
这几天，有关施一公的“新闻”不断。6天前的8月18日，他的研究团队刚刚在《自然》
在线发表了一篇研究长文，首次揭示了分辨率高达3.4埃的人体γ-分泌酶的电镜结构，
为理解阿尔茨海默症的发病机理提供了重要基础。翌日，他拟任清华大学副校长的任命
，进入公示期。
然而，这一次，施一公说，这两篇论文带给他的兴奋，超出了过去25年科研生涯的总和
。
21日中午，记者第一时间赶到清华大学，与施一公和他的3名85后团队成员展开了一场对
话。
“不可能完成的任务”
记者：剪接体结构解析被公认是结构生物学领域的终极难题，你们是如何完成这看似“
不可能完... 阅读全帖 |
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发帖数: 1 | 37 1) I have no comments, but Dr. Chou has mentioned he was able to reproduce
it.
2) DNA band and migration are easily alternated by sample ionic strength and
buffer. The reason lies in the mechanism of DNA molecule electrophoresis is
so different from SDS-PAGE. DNA band shift is not a unusual result if DNA
sample denature or conformation is not consistent because DNA molecules
migrates on a electrical filed by the negative charge of its own phosphate
groups of which the charge is easily altered by... 阅读全帖 |
|
发帖数: 1 | 38 无意中看到一个老外写的，用了下面这篇文章里边介绍的使用荧光标签检控mitophagy。
Tools and techniques to measure mitophagy using fluorescence microscopy
DOI: 10.4161/auto.24001
FP-based biosensors for mitophagy
The field of FP engineering is accelerating with a plethora of new variants
described each year. These proteins show differen- tial properties, many of
which may provide useful tools to study mitophagy. For example, FP-based
biosensors such as a pH- sensitive mitochondrial-targeted FP chimera has
been recently developed to m... 阅读全帖 |
|
发帖数: 1 | 39 无意中看到一个老外写的，用了下面这篇文章里边介绍的使用荧光标签检控mitophagy。
Tools and techniques to measure mitophagy using fluorescence microscopy
DOI: 10.4161/auto.24001
FP-based biosensors for mitophagy
The field of FP engineering is accelerating with a plethora of new variants
described each year. These proteins show differen- tial properties, many of
which may provide useful tools to study mitophagy. For example, FP-based
biosensors such as a pH- sensitive mitochondrial-targeted FP chimera has
been recently developed to m... 阅读全帖 |
|
P*****e
发帖数: 25 | 40 今天有空去查了一下CRISPR专利的历史，UCB的专利已经有claim通过了审查（allow）
，只是还没有issue（时间问题）。我在后面列出来了其中一个通过了的claim，同时把
张锋issue了的专利里面的一个claim也列了出来。大家看能避开不？张锋后来的Cpf1看
着能避开UCB的Cas9。
有意思的是发现最早的一篇CRISPR相关专利申请其实是Luciano A. Marraffini（张锋
合作者）在Northwestern University时申请的，priority date Sep 23, 2008，早了
好几年。看看claim，只有interference，还没进化到切割，可惜一个claim也没批，居
然华丽丽的被一堆112给毙了，也就是审查员觉得那专利写的不清不楚，业内普通人士
看着不可能做出claim的结果，连101，102，103都没用上就挂了。西北也是早早的
abandon了，当年连PCT都没申请，可见并不重视。张锋专利里也没有Marraffini，虽然
science文章有他，我猜可能也是他只做真核interference方面的工作吧，张跟他合作
并进... 阅读全帖 |
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a******n
发帖数: 100 | 41 谢谢回复。我现在在研究一个问题：
https://ghr.nlm.nih.gov/gene/SCN8A
Most of these SCN8A gene mutations change a single protein building block (
amino acid) in the Nav1.6 channel. The mutations that cause SCN8A-related
epilepsy with encephalopathy result in altered channels that stay open
longer than usual, which increases the flow of sodium ions into neurons. The
persistently open channels abnormally increase electrical signals, which
can lead to excess activation (excitation) of neurons in the brain. This
incr... 阅读全帖 |
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m*******u
发帖数: 60 | 42 刚投了一片communication （5 pages）。 三个星期就有结果了，
Referee 1:
Importance: B) highly important
Hypotheses Yes/No: Yes
Appropriate Length: Yes
Different Journal:
Recommend Acceptance: A) Yes, without alterations
Referee 2:
Importance: C) important
Hypotheses Yes/No: No
Appropriate Length: No, the manuscript is too long
Different Journal: Submit as full paper to a highly ranked journal
Recommend Acceptance: C) Yes, but only with major alterations
但是副编辑直接给据了， 建议投全文到其他杂志。 不知有没有必要去argue一下啊？
有用吗？ |
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发帖数: 1 | 43 給臺灣讀者：國立彰化師範大學教授胡瀚平長期抄襲剽竊
劉 正
臺灣教育部領導 暨
國立彰化師範大學校長郭豔光教授（[email protected]/* */）
副校長李清和教授（[email protected]/* */）
副校長陳明飛教授（[email protected]/* */）
國文學系系主任、臺灣文學研究所所長王年雙教授（[email protected]/* */）
您好！
本人是大陸前 武漢大學、中國人民大學、華東師範大學教授、日本國大阪市立大學文
學博士、日本國京都大學博士後研究員。現旅居美國，為美國漢納國際作家協會副會長。
今日在網路上和刊物上驚訝地發現貴大學國文學系暨臺灣文學研究所教授胡瀚平長期抄
襲我的論著，貴所胡瀚平的《易學在西方》一文不加任何說明地全文百分之七十以上全
文抄襲剽竊我的論著。在此，我將貴所胡瀚平的《易學在西方》一文（《國文學志》第
二卷，頁89-103，1998年6月。）全文附上，並附上我的《中國易學預測學》（1991年
，大陸紅旗出版社初版）中的中篇第四章《西方易學史》的145-160頁部... 阅读全帖 |
|
发帖数: 1 | 44 給臺灣讀者：國立彰化師範大學教授胡瀚平長期抄襲剽竊
劉 正
臺灣教育部領導 暨
國立彰化師範大學校長郭豔光教授（[email protected]/* */）
副校長李清和教授（[email protected]/* */）
副校長陳明飛教授（[email protected]/* */）
國文學系系主任、臺灣文學研究所所長王年雙教授（[email protected]/* */）
您好！
本人是大陸前 武漢大學、中國人民大學、華東師範大學教授、日本國大阪市立大學文
學博士、日本國京都大學博士後研究員。現旅居美國，為美國漢納國際作家協會副會長。
今日在網路上和刊物上驚訝地發現貴大學國文學系暨臺灣文學研究所教授胡瀚平長期抄
襲我的論著，貴所胡瀚平的《易學在西方》一文不加任何說明地全文百分之七十以上全
文抄襲剽竊我的論著。在此，我將貴所胡瀚平的《易學在西方》一文（《國文學志》第
二卷，頁89-103，1998年6月。）全文附上，並附上我的《中國易學預測學》（1991年
，大陸紅旗出版社初版）中的中篇第四章《西方易學史》的145-160頁部... 阅读全帖 |
|
w********h
发帖数: 12367 | 45 【 以下文字转载自 Biology 讨论区 】
发信人: tfmm (不是mm), 信区: Biology
标 题: 对话施一公及其团队
发信站: BBS 未名空间站 (Mon Aug 24 07:06:02 2015, 美东)
看一作小姑娘讲的，的确真够拼的啊！
发信人: feimeng (梧桐树，三更雨，不知多少春秋), 信区: TsinghuaCent
标 题: 对话施一公及其团队：世界级难题是如何破解的
发信站: 水木社区 (Mon Aug 24 13:15:21 2015), 站内
8月21日凌晨，一位德国同行的电话，打乱了清华大学生命科学学院院长施一公的工作计
划。这位德国同行，刚刚看到了《科学》在线发表的施一公团队撰写的两篇关于剪接体
结构及其工作机理的研究长文。
这几天，有关施一公的“新闻”不断。6天前的8月18日，他的研究团队刚刚在《自然》
在线发表了一篇研究长文，首次揭示了分辨率高达3.4埃的人体γ-分泌酶的电镜结构，
为理解阿尔茨海默症的发病机理提供了重要基础。翌日，他拟任清华大学副校长的任命
，进入公示期。
然而，这一次，施一公说，这两篇论文带给他的兴奋，超... 阅读全帖 |
|
p********m
发帖数: 325 | 46 Tips on Buying an Interview Suit (ZT)
The suit is the vehicle by which you create a first impression, says Norman
Fryman, former CEO of The Grief Companies and current consultant to
Bidermann, manufacturers of tailored men’s clothing. He goes on to explain
that a suit’s silhouette, drape, and color provoke a conscious thought in
the mind of the recruiter of what you are all about.
Let’s face it, a recruiter not only judges your resume and communication
skills, but will be influenced by the visu... 阅读全帖 |
|
f*****y
发帖数: 847 | 47 Isoniazid has some monoamine oxidase inhibitor (MAOI) activity. Isoniazid
can alter metabolism of tyramine-containing foods, leading to reactions
associated with MAOI drugs (diarrhea, flushing, sweating, pounding chest,
dangerous changes in blood pressure, and other symptoms).People taking
isoniazid should avoid tyramine-containing foods.
Isoniazid can also alter metabolism of histamine-containing foods, leading
to headaches, sweating, pounding chest, flushing, diarrhea, low blood
pressure, and |
|
a*******a
发帖数: 1240 | 48 Before embarking on a metaphysical critique of the famed "theory of general
relativity" (GR) amidst the fanfare of the recent observation by LIGO of
gravitational wave, an explorative discussion of mathematics is both helpful
and necessary.
In any theoretical investigations, mathematics plays a pivotal role. The
natural question arising herein is then, what is mathematics? And what kind
of roles can we possibly expect of mathematics in any theoretical enquiries
(i.e., by deductions) or in a prac... 阅读全帖 |
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a*******y
发帖数: 105 | 49 如何一定要用 datastep， 试试看这个
data b(drop=flag flag2); set a;
by id;
if disp='ALTER' then flag=0;
else flag=1;
retain flag2;
flag2=lag(flag)*flag;
if first.id and disp='PRIMARY' then flag2=1;
else if disp='ALTER' then flag2=0;
if last.id and flag2=1 then output;
run; |
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