b*****h
发帖数: 783 | |
f**********g
发帖数: 2252 | 2 BIAO le 20%!
【在 b*****h 的大作中提到】
: 看看最后的反应，有没有surprise。。呵呵
|
y****8
发帖数: 421 | |
f**********g
发帖数: 2252 | 4 Arena reports Phase 1 results of drug candidate for narcolepsy with
cataplexy
Friday 10/22/2010 9:50 AM ET - Datamonitor
Related Companies
Symbol Last %Chg
ARNA 1.76 20.55%
As of 11:05 AM ET 10/22/10
Arena Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, has
announced results from a Phase 1 clinical trial of APD916, a drug candidate
discovered by Arena that targets the histamine H3 receptor for the
treatment of narcolepsy with cataplexy.
The randomized, double-blind and placebo-controlled trial evaluated the
safety, tolerability and pharmacokinetics of 1mg, 3mg and 5mg single doses
of APD916. The trial evaluated 24 healthy volunteers in three cohorts of
eight participants each, six randomized to APD916 and two to placebo. APD916
demonstrated dose-proportional pharmacokinetic exposure over the tested
dose range. The terminal half-life was approximately 50 hours.
Dose-limiting central nervous system adverse events occurred at the 5mg dose
, including insomnia, abnormal dreams and a nightmare. Adverse events of
insomnia, nausea, headache, parosmia, alterations in perception of body
temperature, abnormal dreams and visual and tactile hallucinations were
commonly reported at the 3mg and 5mg doses, and adverse events of insomnia
were commonly reported at the 1mg dose.
All adverse events in the trial were mild or moderate in nature. No serious
adverse events were reported nor were there any significant safety issues
with respect to vital signs, electrocardiography or laboratory testing.
William Shanahan, senior vice president and chief medical officer of Arena,
said: "APD916 is a highly potent compound, and we believe that exposures of
1mg or less could be sufficient for the intended patient population. We are
currently evaluating next steps for this program."
http://www.datamonitor.com
Republication or redistribution, including by framing or similar means,
is expressly prohibited without prior written consent. Datamonitor shall
not be liable for errors or delays in the content, or for any actions
taken in reliance thereon |
f**********g
发帖数: 2252 | 5 Sell on news. Do not jumped in now. |
b*****h
发帖数: 783 | 6 not the news,,, just for speculation of FDA decision.
【在 f**********g 的大作中提到】
: Sell on news. Do not jumped in now.
|
y****8
发帖数: 421 | |
f**********g
发帖数: 2252 | 8 When is the FDA?
【在 b*****h 的大作中提到】
: not the news,,, just for speculation of FDA decision.
|
b*****h
发帖数: 783 | 9 今天。
【在 f**********g 的大作中提到】
: When is the FDA?
|
b*****h
发帖数: 783 | 10 要真approve就是10x，像以前的vnda |
|
|
y****8
发帖数: 421 | 11 今天FDA啊,那就真的是赌博了.如果不过呢?会跌到多少?
【在 b*****h 的大作中提到】
: 要真approve就是10x，像以前的vnda
|
b*****h
发帖数: 783 | 12 看CRL怎么说吧，估计1刀以下了。
【在 y****8 的大作中提到】
: 今天FDA啊,那就真的是赌博了.如果不过呢?会跌到多少?
|
y****8
发帖数: 421 | 13 Okay,thanks...
【在 b*****h 的大作中提到】
: 看CRL怎么说吧，估计1刀以下了。
|
f**********g
发帖数: 2252 | 14 Do u think what chance arna will pass FDA. 60%, 80%?
【在 b*****h 的大作中提到】
: 要真approve就是10x，像以前的vnda
|
r******2
发帖数: 754 | |
b*****h
发帖数: 783 | 16 基本没希望。
【在 f**********g 的大作中提到】
: Do u think what chance arna will pass FDA. 60%, 80%?
|
r******2
发帖数: 754 | |
f**********g
发帖数: 2252 | 18 Bottom fishing below 1?
【在 b*****h 的大作中提到】
: 基本没希望。
|
w*******d
发帖数: 3714 | 19 0.1%
过了起码值10块，50%值4块，10%值2块，我的理解。。。
【在 f**********g 的大作中提到】
: Do u think what chance arna will pass FDA. 60%, 80%?
|
r******2
发帖数: 754 | 20 估计到不了。
看今天FDA的CRL了。如果只是说需要更多的数据的话，估计就上去了。
如果说就是不行，效果/风险不行的话，估计就下1了。
前者的可能性比较大。可以买点投机一把。我买了1000股
【在 f**********g 的大作中提到】
: Bottom fishing below 1?
|
|
|
f**********g
发帖数: 2252 | 21 Ok. It's lottery now.
How much if it does not pass?
【在 w*******d 的大作中提到】
: 0.1%
: 过了起码值10块，50%值4块，10%值2块，我的理解。。。
|
w*******d
发帖数: 3714 | 22 俺觉得现在这个价就是不过但还能resubmission的公道价。。。
【在 f**********g 的大作中提到】
: Ok. It's lottery now.
: How much if it does not pass?
|
r******2
发帖数: 754 | 23 对头。
【在 w*******d 的大作中提到】
: 俺觉得现在这个价就是不过但还能resubmission的公道价。。。
|
f**********g
发帖数: 2252 | 24 thanks. I already bot some before your post. Very risk, high risk, high
return. Will send u big bonus if win the lottery. I can stand the lost.
【在 r******2 的大作中提到】
: 估计到不了。
: 看今天FDA的CRL了。如果只是说需要更多的数据的话，估计就上去了。
: 如果说就是不行，效果/风险不行的话，估计就下1了。
: 前者的可能性比较大。可以买点投机一把。我买了1000股
|
r******2
发帖数: 754 | 25 呵呵。我是半月前买的。一直没卖，前些日子赚了２０％都没卖。今天又有２０％了。
算了，就当没了。
肯定不会批。不时赌ＬＯＴＴＥＲＹ。而是长期投资。如果跌到１以下，我ＡＤ ＭＯＲＥ
【在 f**********g 的大作中提到】
: thanks. I already bot some before your post. Very risk, high risk, high
: return. Will send u big bonus if win the lottery. I can stand the lost.
|
f**********g
发帖数: 2252 | 26 It's ok if it takes only a small percent of money. Do not all in. Thanks.
ＯＲＥ
【在 r******2 的大作中提到】
: 呵呵。我是半月前买的。一直没卖，前些日子赚了２０％都没卖。今天又有２０％了。
: 算了，就当没了。
: 肯定不会批。不时赌ＬＯＴＴＥＲＹ。而是长期投资。如果跌到１以下，我ＡＤ ＭＯＲＥ
|
r******2
发帖数: 754 | 27 o, forget to tell you. I sell $2 call to collect premium.
So I am OK, if it down. If it above 2, that is OK. I make more (40%).
Thanks.
【在 f**********g 的大作中提到】
: It's ok if it takes only a small percent of money. Do not all in. Thanks.
:
: ＯＲＥ
|
v**********m
发帖数: 5516 | 28 那些给FDA写信的小散真有趣，跟国内的民科有得一拼。 |
f**********g
发帖数: 2252 | 29 I heard a lecture bofore to use options to hedge stocks. Very good. I need
learn how to play options in the future.
There are lots of calls $2, $1.5, $3, $2.5, and $1 now.
Nov 10
0.85
1,551 1.40
1,276 0
0 0.00 |
