p*******m
发帖数: 24 | 1 In gain-of-function analysis, a microbiologist can enhance the lethality of
a coronavirus enormously by splicing a particular sequence into its genome
at a main location.
As an alternative of a CGG-CGG (often called “double CGG”) that tells the
protein manufacturing unit to make two arginine amino acids in a row, you’
ll receive equal lethality by splicing any considered one of 35 of the
opposite two-word combos for double arginine.
Though the double CGG is suppressed naturally, the alternative is true in
laboratory work.
When the lab’s Shi Zhengli
and colleagues printed a paper in February 2020 with the virus’s partial
genome, they omitted any point out of the particular sequence that
supercharges the virus or the uncommon double CGG part. But the fingerprint
is well recognized within the knowledge that accompanied the paper. Was it
omitted within the hope that no person would discover this proof of the gain
-of-function origin?
However in a matter of weeks virologists Bruno Coutard
and colleagues printed their discovery of the sequence in CoV-2 and its
novel supercharged website. Double CGG is there; you solely need to look.
They remark of their paper that the protein that held it “could present a
gain-of-function” functionality to the virus, “for environment friendly
spreading” to people.
the viruses advanced quickly as they unfold by the human inhabitants, till
essentially the most contagious kinds dominated. Such early optimization is
unprecedented, and it suggests a protracted interval of adaptation that
predated its public unfold.
https://www.wsj.com/articles/the-science-suggests-a-wuhan-lab-leak-
11622995184 | n***t
发帖数: 126 | | p*******m
发帖数: 24 | 3 这坑早就挖好了，现在人造是没跑了，最后回到中共军方舟山蝙蝠病毒骨架。
蝠奇也好，德堡也好，美国撤梯子走人。
【在 n***t 的大作中提到】
: 五毛也在拼命叫要彻查，这下两边意见统一了。
| m*********9
发帖数: 56 | 4 原始病毒骨架在五毒所
of
the
【在 p*******m 的大作中提到】
: In gain-of-function analysis, a microbiologist can enhance the lethality of
: a coronavirus enormously by splicing a particular sequence into its genome
: at a main location.
: As an alternative of a CGG-CGG (often called “double CGG”) that tells the
: protein manufacturing unit to make two arginine amino acids in a row, you’
: ll receive equal lethality by splicing any considered one of 35 of the
: opposite two-word combos for double arginine.
: Though the double CGG is suppressed naturally, the alternative is true in
: laboratory work.
: When the lab’s Shi Zhengli
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