h******1
发帖数: 94 | 1 In the manual,
http://www.broadinstitute.org/gsea/doc/GSEAUserGuide.pdf
On the page 7, right above "Phenotype Labels", it says
"The GSEA algorithm does not filter the expression dataset and does not
benefit from your filtering of the expression dataset. During the analysis,
genes that are poorly expressed or that have low variance across the dataset
populate the middle of the ranked gene list and the use of a weighted
statistic ensures that they do not contribute to a positive enrichmen | g********r
发帖数: 8017 | 2 没用过.但你说的这个case不是"low variance across the dataset"吧?很大的
variance呀.
,
dataset
score
easily
【在 h******1 的大作中提到】
: In the manual,
: http://www.broadinstitute.org/gsea/doc/GSEAUserGuide.pdf
: On the page 7, right above "Phenotype Labels", it says
: "The GSEA algorithm does not filter the expression dataset and does not
: benefit from your filtering of the expression dataset. During the analysis,
: genes that are poorly expressed or that have low variance across the dataset
: populate the middle of the ranked gene list and the use of a weighted
: statistic ensures that they do not contribute to a positive enrichmen
| f*********8
发帖数: 165 | 3 what do you mean by "offset in the side of GSEA"? |
|
