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Postdoc版 - call for reviewers (转载)
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发帖数: 238
1
【 以下文字转载自 Biology 讨论区 】
发信人: gifted (sentosa), 信区: Biology
标 题: call for reviewers (转载)
发信站: BBS 未名空间站 (Wed Apr 5 23:38:57 2017, 美东)
发信人: gifted (sentosa), 信区: EB23
标 题: call for reviewers
发信站: BBS 未名空间站 (Wed Apr 5 21:03:58 2017, 美东)
OAP 旗下 International Journal of Clinical Microbiology,无分非SCI哦,稿件情
况如下:
Title: Transcription regulators MarA, SoxS and Rob and CTX-M beta-lactamase
gene sequences as potential diagnostic biomarker in monitoring and
management of antibiotic treatment
Abstract:
Abstract
Extended Spectrum Beta Lactamases (ESBLs) are resistance enzymes that are
responsible for antibiotic resistance and are produced by the CTX-M beta-
lactamase gene in Gram-negative pathogens, such as antibiotic resistant
Escherichia coli. This study uses a bioinformatic approach in identifying
and understanding gene expression regulation between transcription factors
MarA, SoxS, Rob and blaCTX-M promoter as well as investigating the presence
of a consensus sequence within CTX-M groups to determine possibility of
identifying diagnostic markers. It was found through gene analysis that SoxS
and MarA has a high possibility of regulating several CTX-M genes of
different phylogeny. Therefore there is a possibility in reducing antibiotic
resistant traits or enhance antibiotic treatment efficiency against
antibiotic resistant bacterial pathogens. Furthermore, a consensus sequence
was obtained within CTX-M groups, however the length of the sequence was not
sufficient enough to create an ideal primer to target during polymerase
chain reaction to act as a diagnostic biomarker. Further research needed to
be done to widen the search range surrounding the beta-lactamase gene to
find a consensus sequence relating to the function and expression of
antibiotic resistance. In this study, we have consider the prospect of
possible potential in enhancing antibiotic resistant treatments and
diagnostics as well as measuring its progress and effectiveness in patients.
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进入Postdoc版参与讨论
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Postdoc Opening at Univ Wisconsin-Madison招聘博士后 - 亚利桑那大学医学院
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博士后招聘J1博后求审稿(biosensor,Biomarker,analytical chemistry)
call for reviewer我来发个最近申请H1B的材料清单吧
求审稿Question about applying for postdoc position
上海联合利华招聘美国博士graduate transcript 是不是指研究生阶段的成绩单呢?
相关话题的讨论汇总
话题: antibiotic话题: ctx话题: gene话题: resistant话题: mara