r*******u 发帖数: 156 | 1 文章杂志的修稿意见回来了, 可是找不到文献资料全文, 那位同学能帮助一下?
There is an article that should be referenced by Bastarache J et al in J
Crit Care 2010 that shows that AFC is faster in women than in men patients.
This should be added to the reference list. | q****n 发帖数: 5 | 2 J Crit Care. 2010 Aug 3. [Epub ahead of print]
Alveolar fluid clearance is faster in women with acute lung injury compared
to men.
Bastarache JA, Ong T, Matthay MA, Ware LB.
Source
Division of Allergy, Pulmonary and Critical Care Medicine, Department of
Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2650
, USA.
Abstract
PURPOSE:
Studies suggest that there is a sex difference in the development and
outcomes of acute lung injury (ALI). Few studies have directly addressed the
association of sex and alveolar fluid clearance (AFC), a process that is
critical to ALI resolution.
MATERIALS AND METHODS:
To test the hypothesis that female sex is associated with an increased AFC
rate, we measured AFC rates in 150 mechanically ventilated patients with
acute pulmonary edema and a pulmonary edema fluid-to-plasma protein ratio (
EF/PL) diagnostic of low permeability (EF/PL <0.65, n = 69) or high
permeability (EF/PL >/=0.65, n = 81) edema. We measured protein
concentration in serial samples of undiluted EF collected within 6 hours of
intubation and calculated net rate of AFC. In addition, plasma levels of
receptor for advanced glycation end products were measured as a surrogate
marker for alveolar epithelial injury.
RESULTS:
In patients with ALI, women had higher rates of net AFC at 4 hours compared
to men (11.9% per hour vs 4.3% per hour, P = .017) and more women had
maximal rates of AFC. There were no differences in circulating levels of
receptor for advanced glycation end products between men and women.
CONCLUSIONS:
These findings may have significant implications for future ALI studies and
potential therapies.
Published by Elsevier Inc. | r*******u 发帖数: 156 | 3 Thank you very much.
compared
2650
【在 q****n 的大作中提到】 : J Crit Care. 2010 Aug 3. [Epub ahead of print] : Alveolar fluid clearance is faster in women with acute lung injury compared : to men. : Bastarache JA, Ong T, Matthay MA, Ware LB. : Source : Division of Allergy, Pulmonary and Critical Care Medicine, Department of : Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2650 : , USA. : Abstract : PURPOSE:
| r*******u 发帖数: 156 | 4 Bao zi were sent.
【在 r*******u 的大作中提到】 : Thank you very much. : : compared : 2650
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