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发帖数: 33 | 1 POSITION SUMMARY
A Senior Scientist who will play a key role in new drug characterization and
analysis using LC/MS in research and development. Major responsibilities
include bioanalytical assay development for drug DMPK studies and peptide/
protein and antibody analysis in support of drug candidate selection,
preclinical and IND-enabling studies
ESSENTIAL FUNCTIONS
- Peptide/protein and antibody analysis using Agilent QTOF
- Developing in vitro DMPK assays using SCIEX QTRAP including metabolic
stability, metabolite profiling, structure elucidation, and CYP450
inhibition assays
- Preclinical bioanalytical assays for PK studies to determine drug
concentration in plasma, urine, and different tissues
- PK calculations and interpretation using Phoenix WinNonlin software
- LC/MS instrument maintenance and trouble shooting
EDUCATION/EXPERIENCE REQUIREMENTS
Ph.D in chemistry with more than 7 years pharmaceutical experience using LC/
MS
REQUIRED COMPETENCIES – KNOWLEDGE, SKILLS, ABILITIES
- Expert in Mass Spectrometry for small molecule and protein analysis
- Strong knowledge in DMPK study
- Skillful in bioanalytical assay development
If you feel interested, please contact Sherry via email [email protected]
com.
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