u****n
发帖数: 12 | | k**a
发帖数: 284 | 2 好像是纯化技术的问题, 他们用酵母表达
luo用e coli
【在 u****n 的大作中提到】
: 哪位牛人给说说？
| a*******o
发帖数: 280 | 3 sounds pretty scary
it is not only the issue of purification, but also glycosylation, folding,
immunogenicity, pharmacokinetics, binding property.
How dare he inject this to human?
【在 k**a 的大作中提到】
: 好像是纯化技术的问题, 他们用酵母表达
: luo用e coli
| H*Q
发帖数: 725 | 4 because endostatin did not work in humans.
【在 u****n 的大作中提到】
: 哪位牛人给说说？
| H*Q
发帖数: 725 | 5 In a Phase II clinical trial of Endostatin forty two patients with
pancreatic endocrine tumors or carcinoid tumors were treated.[3] Of the 40
patients which could be evaluated for a radiologic response, none
experienced partial response to therapy, as defined by World Health
Organization criteria. The conclusion from the trial was that "Treatment
with rhEndostatin did not result in significant tumor regression in patients
with advanced neuroendocrine tumors."
http://en.wikipedia.org/wiki/Endosta | c*u
发帖数: 21 | 6 产品名称: 重组人血管生成抑制素Endostatin | c*u
发帖数: 21 | |
|
