e***o 发帖数: 344 | 1 版上有几个做这个方向的。能不能简单给讲讲?antibody 无法通过血脑屏障。一直好
奇比如
neurotrophic virus,bacteria 或其他有害的东西入侵大脑后,神经免疫系统如何反应
。曾经看
过一篇文章说neuron 可以fight back.....但主要还是glial cell 负责把?? | n***w 发帖数: 2405 | 2 microglia.
I am not sure about the brain, but in retina, we observed that there is
infiltration of macrophages and other inflammatory cells.
would you please share the paper?
Thanks. | e***o 发帖数: 344 | 3 谢谢!microglia的反应机制应该类似innate immunity吧。不知道他是怎样识别自我和
非自我的。
我说的文章在这里。还有 一篇comments,找不到了。
J Virol. 2005 Oct;79(20):12893-904.
Virus infection switches TLR-3-positive human neurons to become strong
producers of beta interferon.
Préhaud C, Mégret F, Lafage M, Lafon M.
Source | n***w 发帖数: 2405 | 4 YES. We start to work on TLR2,4 in the retina too. lol |
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