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Moderna Inc. said Thursday it expects people who received its two-dose Covid
-19 vaccine to need a booster shot in the fall to keep strong protection
against newer variants of the coronavirus.
The company said its vaccine remains 90% effective against preventing Covid-
19 disease for at least six months, but said it sees a decline in antibody
levels after six months, especially against newer strains of the coronavirus
including the Delta variant. In a Phase 2 study, a third shot of the
original formulation showed robust antibody responses against Covid-19
variants of concern, Moderna said.
Moderna Chief Executive Stéphane Bancel said in an interview Thursday that
the company plans to seek regulatory approval for its booster shots in
September, after it analyzes data from ongoing trials.
He said the boosters are necessary because immunity will continue to wane
over time and some vaccine recipients show a drop in neutralizing antibodies
when exposed to some variants, including Delta.
“We’re playing it safe, not only for Delta but also for what’s coming
after,” he said. “I don’t think the virus is done.” |
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