F******k 发帖数: 7375 | 1 发信人: cllearjks (cllearjks), 信区: Military
标 题: Re: 剑桥:最原始毒株普遍存在于美国 中国流行的是变异毒株
发信站: BBS 未名空间站 (Fri Apr 10 11:03:31 2020, 美东)
Mutated versions of ‘A’ were seen in Americans reported to have lived in
Wuhan, and a large number of A-type viruses were found in patients from the
US and Australia.
A的突变版本的病毒是在居住在武汉的美国人中发现的,并且大量的A类型病毒在美国和
澳大利亚被发现。
Wuhan’s major virus type, ‘B’, was prevalent in patients from across East
Asia. However, the variant didn’t travel much beyond the region without
further mutations – implying a "founder event" in Wuhan, or “resistance”
against this type of COVID-19 outside East Asia, say researchers.
武汉的主要病毒类型B,在东亚病人中流行。然而,这一种群在没有进一步突变的情况
下没有跨区域流行,暗示了武汉的奠基者事件,或者说,阻力抵挡了这一类型在东亚以
外的地区传播,据研究人员说。
科普一下 the founder effect
The founder effect is a case of genetic drift caused by a small population
with limited numbers of individuals breaking away from a parent population.
The occurrence of retinitis pigmentosa in the British colony on the Tristan
da Cunha islands is an example of the founder effect.
https://zh.wikipedia.org/zh-cn/奠基者效应
The ‘C’ variant is the major European type, found in early patients from
France, Italy, Sweden and England. It is absent from the study’s Chinese
mainland sample, but seen in Singapore, Hong Kong and South Korea.
C种群是欧洲主要类型,在法国,意大利,瑞典和英国的早期病人中被发现。他们在中
国大陆的研究采样中缺失,但是在新加坡,香港和韩国被发现。
这几段上面说明几个问题:
第一,美国人主要流行的A类型,有武汉居住史。
第二,美国的大流行类型,不是从欧洲来的,而是从中国来的。
第三,中共隐瞒了C类型数据。
第四,A类型数据较少的原因,有可能是该类型数据没有被充分采样和上传,并不一定
是A类型在武汉传染的人数少。
最重要的一点:只在武汉才发现有奠基者效应! | y******m 发帖数: 143 | 2 The authors claimed that Node B is derived from A by two mutations: the
synonymous mutation T8782C and the nonsynonymous mutation C28144T changing a
leucine to a serine. However, based on the biochemistry knowledge, serine
is a nonessential amino acid, not stable and more easily mutant to another
Amino acid. leucine is essential amino acid. In another words, it is not
possible to happen this mutation in vivo.
所有的论据来自于一个错误的假设和有限的只取3月早期的数据,就一罐水的破文 | l*********r 发帖数: 695 | 3 美国和世界各国早期只测试有明确接触史和旅行史的病例是不是COVID-19阳性,而且可
以想象,各国对这种所谓的外来输入的“第一例”是一定会测序的。
根据这种人工筛选的样本进行测序,就一定能得到跟旅行一样的进化树
真正的进化树,需要随机采样
早期的数据已经不能用了 |
|