k**e
发帖数: 2728 | 1 When giving out answer, it is highly encouraging to also give out your logic
al analysis on how you decide the answer you choose :)
1. The rate of glycogen degradation in skeletal muscles increases several hu
ndred-fold after the onset of contraction compared to the resting state. Thi
s finding reflects enzyme activation by which of the following substances?
A. ADP
B. cAMP
C. CA2+
D. Lactate
E. Glucose-6-phosphate
2. A 64-year-old male hospitalized with severe abdominal pain and hypotensio
n beg |
s**********r
发帖数: 178 | 2 1C Ca2+ activates muscle glycogen phosphorylase
2C pyruvate can not enter the TCA cycle. |
s**********r
发帖数: 178 | 3 第二个好像是nbme的题吧？ 这样会不会干扰模拟题测试的准确性？ |
m***d
发帖数: 441 | 4 以后贴NBME的题的时候在标题注明NBME的题和哪一套吧 |
k**e
发帖数: 2728 | 5 nope! i haven't gone that far to NBME... :) don't worry... and I will not po
st any questions from NBME either. I think if people want to talk about that
, they will set up their own discussion posts with indication...
【在 s**********r 的大作中提到】
: 第二个好像是nbme的题吧？ 这样会不会干扰模拟题测试的准确性？
|
k**e
发帖数: 2728 | 6 nice.. i like your concise thinking.
sometimes i tend to analyze more about the whole situation before leading to
the final conclusion... that kind of waste time though, somehow i still enj
oy it :p
i'll post answer with explanation behind the scene later.
【在 s**********r 的大作中提到】
: 1C Ca2+ activates muscle glycogen phosphorylase
: 2C pyruvate can not enter the TCA cycle.
|
k**e
发帖数: 2728 | 7 Answer:
1. C
Glycogen degradation is coupled with skeletal muscles contraction due to
calcium-mediated myophosphorylase activation. The neurotransmitter
acetylcholine stimulates the contract of muscle, and then causes
depolarization of the muscle cell and release of calcium from the
sarcoplasmic reticulum into the cytosol. Increase calcium in the cytosol
binds troponin C to cause muscle contraction and also activates muscle
glycogen phosphorylase to provide energy for the working muscle.
2. C
hy |
