w********h
发帖数: 12367 | |
b**s
发帖数: 589 | 2 50:50 PLGA, maybe
【在 w********h 的大作中提到】
: ???
|
w********h
发帖数: 12367 | 3 can we get both fair mechainical property and degradation rate?
【在 b**s 的大作中提到】
: 50:50 PLGA, maybe
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b**s
发帖数: 589 | 4 Probably need to try hybrid, just like polymer 共混
Also I got a question for you, Do you think if natural polymer and
synthetic polymer 共混 will be extremly difficult in most cases?
1. The MW of natural polymer normally is much larger than synthetic
polymer's
2. natural polymer normally H2O-philic and the latter phobic
【在 w********h 的大作中提到】
: can we get both fair mechainical property and degradation rate?
|
m***n
发帖数: 266 | 5 我听说有把某些polymer和amino acid共混的.比如polyurethane,硬度和亲/憎水性都是很
容易调节的,也可以做成biodegradable.
【在 b**s 的大作中提到】
: Probably need to try hybrid, just like polymer 共混
: Also I got a question for you, Do you think if natural polymer and
: synthetic polymer 共混 will be extremly difficult in most cases?
: 1. The MW of natural polymer normally is much larger than synthetic
: polymer's
: 2. natural polymer normally H2O-philic and the latter phobic
|
w********h
发帖数: 12367 | 6 don't quite understand your question here.
you mean a particular case or a general one?
natural polymers are not necessarily hydrophilic,
or much higher molecular weight.
PEG, PGA are hydrophilic.
while normal natural rubber (PBD and PIP) is hydrophobic.
there are not many pairs of miscible blends.
【在 b**s 的大作中提到】
: Probably need to try hybrid, just like polymer 共混
: Also I got a question for you, Do you think if natural polymer and
: synthetic polymer 共混 will be extremly difficult in most cases?
: 1. The MW of natural polymer normally is much larger than synthetic
: polymer's
: 2. natural polymer normally H2O-philic and the latter phobic
|
c*w
发帖数: 50 | 7
Not exactly correct. PLA, PLGA and PLGA are hydrophibic, which makes the
implants or drug delivery devices opsonization in vivo. such shortcoming
results in a lot of work on the synthesis of Poly(ethylene glycol)-pLA
copolymers.
【在 w********h 的大作中提到】
: don't quite understand your question here.
: you mean a particular case or a general one?
: natural polymers are not necessarily hydrophilic,
: or much higher molecular weight.
: PEG, PGA are hydrophilic.
: while normal natural rubber (PBD and PIP) is hydrophobic.
: there are not many pairs of miscible blends.
|
b*******n
发帖数: 29 | 8 Why are PLA and PLGA hydrophilic?
I am confused.
【在 w********h 的大作中提到】
: don't quite understand your question here.
: you mean a particular case or a general one?
: natural polymers are not necessarily hydrophilic,
: or much higher molecular weight.
: PEG, PGA are hydrophilic.
: while normal natural rubber (PBD and PIP) is hydrophobic.
: there are not many pairs of miscible blends.
|
m***n
发帖数: 266 | 9 严格说起来，PLA is hydrophobic.
【在 w********h 的大作中提到】
: don't quite understand your question here.
: you mean a particular case or a general one?
: natural polymers are not necessarily hydrophilic,
: or much higher molecular weight.
: PEG, PGA are hydrophilic.
: while normal natural rubber (PBD and PIP) is hydrophobic.
: there are not many pairs of miscible blends.
|
