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发帖数: 263 | 1 An new study from nine labs leads to Partial Retraction of a 2009 Science paper, or even more papers will be retracted:
Failure to Confirm XMRV/MLVs in the Blood of Patients with Chronic Fatigue
Syndrome: A Multi-Laboratory Study
Published Online September 22 2011 Science 11 November 2011:
Vol. 334 no. 6057 pp. 814-817 DOI: 10.1126/science.1213841
Abstract
Murine leukemia viruses (MLVs), including xenotropic-MLV–related virus (
XMRV), have been controversially linked to chronic fatigue syndrome (CFS).
To explore this issue in greater depth, we compiled coded replicate samples
of blood from 15 subjects previously reported to be XMRV/MLV–positive (14
with CFS) and from 15 healthy donors previously determined to be negative
for the viruses. These samples were distributed in a blinded fashion to nine
laboratories, which performed assays designed to detect XMRV/MLV nucleic
acid, virus replication, and antibody. Only two laboratories reported
evidence of XMRV/MLVs; however, replicate sample results showed disagreement
, and reactivity was similar among CFS subjects and negative controls. These
results indicate that current assays do not reproducibly detect XMRV/MLV in
blood samples and that blood donor screening is not warranted.
http://www.sciencemag.org/content/334/6057/814.abstract
Partial Retraction
Science 14 October 2011: 176.Published online 22 September 2011
http://www.sciencemag.org/content/334/6053/176.1.full |
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