m**********g
发帖数: 24 | 1 Transcription factor, Nuclear transcription factor 和 Nuclear factor 它们是
同一个东西吗？ 它们是否一定仅表达在细胞核里面？有可能表达在胞浆里吗？
谢谢！ | n***w
发帖数: 2405 | 2 I am not sure about nuclear factor.
I guess transcription factor and nuclear transcription factor are
interchangeable in most cases.
They can be expressed and latent in the cytoplasm and translocate to the
nucleus upon activation, for example, STAT3, NF-kB.
Also they can be nuclear encoded but transported to mitochondria to direct
transcription like Tfam. | j****x
发帖数: 1704 | 3 这个nuclear transcription factor是相对于mitochondrial transcription factor和
cytoplasmic transcription factor而言的，所以显然不能等同于transcription
factor
倒是nuclear factor和nuclear transcription factor广义上应该是一回事
【在 n***w 的大作中提到】
: I am not sure about nuclear factor.
: I guess transcription factor and nuclear transcription factor are
: interchangeable in most cases.
: They can be expressed and latent in the cytoplasm and translocate to the
: nucleus upon activation, for example, STAT3, NF-kB.
: Also they can be nuclear encoded but transported to mitochondria to direct
: transcription like Tfam.
| m**********g
发帖数: 24 | 4 很有帮助， 很受启发！谢谢！
【在 n***w 的大作中提到】
: I am not sure about nuclear factor.
: I guess transcription factor and nuclear transcription factor are
: interchangeable in most cases.
: They can be expressed and latent in the cytoplasm and translocate to the
: nucleus upon activation, for example, STAT3, NF-kB.
: Also they can be nuclear encoded but transported to mitochondria to direct
: transcription like Tfam.
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