i******e 发帖数: 171 | 1 Toshiyuki Hayakawa,1,2* Takashi Angata,1,2* Amanda L. Lewis,1,3 Tarjei S
. Mikkelsen,6 Nissi M. Varki,1,4 Ajit Varki1,2,5
Recent studies have shown multiple differences between humans and apes i
n sialic acid (Sia) biology, including Siglecs (Sia-recognizing-Ig-super
family lectins). Comparisons with the chimpanzee genome indicate that hu
man SIGLEC11 emerged through human-specific gene conversion by an adjace
nt pseudogene. Conversion involved 5?untranslated sequences and the Sia-
recognition d |
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